Synthesis of glycaro-1,5-lactams and tetrahydrotetrazolopyridine-5- carboxylates: Inhibitors of β-D-glucuronidase and α-L-iduronidase

Helvetica Chimica Acta

Volumn 89, Issue 4, 2006, Pages 635-666

  Pabba, Jagadish ^a   Rempel, Brian P ^b   Withers, Stephen G ^b   Vasella, Andrea ^a  

^a ETH ZURICH   (Switzerland)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME INHIBITION; ENZYMES; ESTERIFICATION; REACTION KINETICS; REDUCTION; SAPONIFICATION;

DIHYDROXYLATION; GLYCARO-1,5-LACTAMS; L-IDURONIDASES; TETRAHYDROTETRAZOLOPYRIDINE;

CARBOHYDRATES;

1 ETHYL 6 METHYL 4,5 DI O BENZYL 2,3 DIDEOXY LEVO THREO HEX 2 ENARATE; 1,6 DIMETHYL 4,5 DI O BENZYL 2,3 DIDEOXY LEVO THREO HEX 2 ENARATE; 4 AMINO 4,5 DIDEOXY LEVO ARABINARO 1,4 LACTAM; 4 METHYL 2,3 DI O BENZYL LEVO THREURONATE; 6 ETHYL 5 AMINO 2,3 DI O BENZYL 5 DEOXY DEXTRO GLUCARATE 1,5 LACTAM; 6 METHYL 5 AMINO 2,3 DI O BENZYL 5 DEOXY DEXTRO GALACTARATE 1,5 LACTAM; 6 METHYL 5 AMINO 2,3 DI O BENZYL 5 DEOXY LEVO IDARATE 1,5 LACTAM; 6 SODIUM 5 AMINO 5 DEOXY DEXTRO GALACTARATE 1,5 LACTAM; 6 SODIUM 5 AMINO 5 DEOXY LEVO ALTRARATE 1,5 LACTAM; 6 SODIUM 5 AMINO 5 DEOXY LEVO IDARATE 1,5 LACTAM; BETA GLUCURONIDASE; CARBOXYLIC ACID DERIVATIVE; LACTAM DERIVATIVE; LEVO IDURONIDASE; SODIUM 5,6,7,8 TETRAHYDRO 6,7,8 TRIHYDROXYTETRAZOLO[1,2 A]PYRIDINE 5 CARBOXYLATE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; COW; DEPROTECTION REACTION; DIHYDROXYLATION; DRUG INHIBITION; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TRANSFORMATION; ENZYME INHIBITION; ESTERIFICATION; HYDROGENOLYSIS; LACTONIZATION; LIVER; NONHUMAN; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; REDUCTION; SAPONIFICATION;

EID: 33646258986     PISSN: 0018019X     EISSN: None     Source Type: Journal    
DOI: 10.1002/hlca.200690066     Document Type: Article

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