-
1
-
-
0033543992
-
High-capacity adenoviral vectors for gene transfer and somatic gene therapy
-
Kochanek S. High-capacity adenoviral vectors for gene transfer and somatic gene therapy. Hum Gene Ther 1999; 10: 2451-2459.
-
(1999)
Hum Gene Ther
, vol.10
, pp. 2451-2459
-
-
Kochanek, S.1
-
2
-
-
13144283616
-
An adenoviral vector deleted for all viral coding sequences results in enhanced safety and extended expression of a leptin transgene
-
Morsy MA, Gu M, Motzel S, et al. An adenoviral vector deleted for all viral coding sequences results in enhanced safety and extended expression of a leptin transgene. Proc Natl Acad Sci USA 1998; 95: 7866-7871.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 7866-7871
-
-
Morsy, M.A.1
Gu, M.2
Motzel, S.3
-
3
-
-
0031916435
-
Genomic DNA transfer with a high-capacity adenovirus vector results in improved in vivo gene expression and decreased toxicity
-
Schiedner GMN, Parks RJ, Wu Y, et al. Genomic DNA transfer with a high-capacity adenovirus vector results in improved in vivo gene expression and decreased toxicity. Nat Genet 1998; 18:180-183.
-
(1998)
Nat Genet
, vol.18
, pp. 180-183
-
-
Schiedner, G.M.N.1
Parks, R.J.2
Wu, Y.3
-
4
-
-
12944317288
-
Sustained high-level expression of full-length human factor VIII and restoration of clotting activity in hemophilic mice using a minimal adenovirus vector
-
Balagué C Zhou J, Dai Y, et al. Sustained high-level expression of full-length human factor VIII and restoration of clotting activity in hemophilic mice using a minimal adenovirus vector. Blood 2000; 95:820-828.
-
(2000)
Blood
, vol.95
, pp. 820-828
-
-
Balagué, C.1
Zhou, J.2
Dai, Y.3
-
5
-
-
14344276590
-
An improved helper-dependent adenoviral vector allows persistent gene expression after intramuscular delivery and overcomes preexisting immunity to adenovirus
-
Maione D, Della Rocca C, Giannetti P, et al. An improved helper-dependent adenoviral vector allows persistent gene expression after intramuscular delivery and overcomes preexisting immunity to adenovirus. Proc Natl Acad Sci USA 2001; 98: 5986-5991.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 5986-5991
-
-
Maione, D.1
Della Rocca, C.2
Giannetti, P.3
-
6
-
-
0036592086
-
A new adenoviral helper-dependent vector results in long-term therapeutic levels of human coagulation factor IX at low doses in vivo
-
Ehrhardt A, Kay MA. A new adenoviral helper-dependent vector results in long-term therapeutic levels of human coagulation factor IX at low doses in vivo. Blood 2002; 99: 3923-3930.
-
(2002)
Blood
, vol.99
, pp. 3923-3930
-
-
Ehrhardt, A.1
Kay, M.A.2
-
7
-
-
0037566365
-
Long-term stable expression of human apolipoprotein A-I mediated by helper-dependent adenovirus gene transfer inhibits atherosclerosis progression and remodels atherosclerotic plaques in a mouse model of familial hypercholesterolemia
-
Belalcazar LM, Merched A, Carr B, et al. Long-term stable expression of human apolipoprotein A-I mediated by helper-dependent adenovirus gene transfer inhibits atherosclerosis progression and remodels atherosclerotic plaques in a mouse model of familial hypercholesterolemia. Circulation 2003; 107: 2726-2732.
-
(2003)
Circulation
, vol.107
, pp. 2726-2732
-
-
Belalcazar, L.M.1
Merched, A.2
Carr, B.3
-
8
-
-
0038344798
-
Prolonged dystrophin expression and functional correction of mdx mouse muscle following gene transfer with a helper-dependent (gutted) adenovirus-encoding murine dystrophin
-
Gilbert R, Dudley RW, Liu AB, Petrof BJ, Nalbantoglu J, Karpati G. Prolonged dystrophin expression and functional correction of mdx mouse muscle following gene transfer with a helper-dependent (gutted) adenovirus-encoding murine dystrophin. Hum Mol Genet 2003; 12: 1287-1299.
-
(2003)
Hum Mol Genet
, vol.12
, pp. 1287-1299
-
-
Gilbert, R.1
Dudley, R.W.2
Liu, A.B.3
Petrof, B.J.4
Nalbantoglu, J.5
Karpati, G.6
-
9
-
-
0036172199
-
Superior tissue-specific expression from tyrosinase and prostate-specific antigen promoters/enhancers in helper-dependent compared with first-generation adenoviral vectors
-
Shi CX, Hitt M, Ng P, Graham FL. Superior tissue-specific expression from tyrosinase and prostate-specific antigen promoters/enhancers in helper-dependent compared with first-generation adenoviral vectors. Hum Gene Ther 2002; 13: 211-224.
-
(2002)
Hum Gene Ther
, vol.13
, pp. 211-224
-
-
Shi, C.X.1
Hitt, M.2
Ng, P.3
Graham, F.L.4
-
10
-
-
0032506791
-
High doses of a helper-dependent adenoviral vector yield supraphysiological levels of alpha1 -antitrypsin with negligible toxicity
-
Morral N Parks RJ, Zhou H, et al. High doses of a helper-dependent adenoviral vector yield supraphysiological levels of alpha1 -antitrypsin with negligible toxicity. Hum Gene Ther 1998; 9:2709-2716.
-
(1998)
Hum Gene Ther
, vol.9
, pp. 2709-2716
-
-
Morral, N.1
Parks, R.J.2
Zhou, H.3
-
11
-
-
0034152718
-
Toxicity associated with repeated administration of first-generation adenovirus vectors does not occur with a helper-dependent vector
-
O'Neal WK, Zhou H, Morral N, et al. Toxicity associated with repeated administration of first-generation adenovirus vectors does not occur with a helper-dependent vector. Mol Med 2000; 6: 179-195.
-
(2000)
Mol Med
, vol.6
, pp. 179-195
-
-
O'Neal, W.K.1
Zhou, H.2
Morral, N.3
-
12
-
-
0742307422
-
Acute toxicity after high-dose systemic injection of helper-dependent adenoviral vectors into nonhuman primates
-
Brunetti-Pierri N, Palmer DJ, Beaudet AL, Carey KD, Finegold M, Ng P. Acute toxicity after high-dose systemic injection of helper-dependent adenoviral vectors into nonhuman primates. Hum Gene Ther 2004; 15: 35-46.
-
(2004)
Hum Gene Ther
, vol.15
, pp. 35-46
-
-
Brunetti-Pierri, N.1
Palmer, D.J.2
Beaudet, A.L.3
Carey, K.D.4
Finegold, M.5
Ng, P.6
-
13
-
-
0030462599
-
A helper-dependent adenovirus vector system: Removal of helper virus by Cre-mediated excision of the viral packaging signal
-
Parks RJ, Chen L, Anton M, Sankar U, Rudnicki MA, Graham FL. A helper-dependent adenovirus vector system: removal of helper virus by Cre-mediated excision of the viral packaging signal. Proc Natl Acad Sci USA 1996; 93: 13565-13570.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 13565-13570
-
-
Parks, R.J.1
Chen, L.2
Anton, M.3
Sankar, U.4
Rudnicki, M.A.5
Graham, F.L.6
-
14
-
-
0030900511
-
A helper-dependent system for adenovirus vector production helps define a lower limit for efficient DNA packaging
-
Parks RJ, Graham FL. A helper-dependent system for adenovirus vector production helps define a lower limit for efficient DNA packaging. J Virol 1997; 71: 3293-3298.
-
(1997)
J Virol
, vol.71
, pp. 3293-3298
-
-
Parks, R.J.1
Graham, F.L.2
-
15
-
-
4644305734
-
The human SCGB2A2 (mammaglobin-1) promoter/enhancer in a helper-dependent adenovirus vector directs high levels of transgene expression in mammary carcinoma cells but not normal non-mammary cells
-
Shi C-X, Long MA, Liu L, Graham FL, Gauldie J, Hitt M. The human SCGB2A2 (mammaglobin-1) promoter/enhancer in a helper-dependent adenovirus vector directs high levels of transgene expression in mammary carcinoma cells but not normal non-mammary cells. Mol Ther 2004; 10: 758-767.
-
(2004)
Mol Ther
, vol.10
, pp. 758-767
-
-
Shi, C.-X.1
Long, M.A.2
Liu, L.3
Graham, F.L.4
Gauldie, J.5
Hitt, M.6
-
16
-
-
0035831605
-
System for efficient helper-dependent minimal adenovirus construction and rescue
-
Hillgenberg M, Schnieders F, Loser P, Strauss M. System for efficient helper-dependent minimal adenovirus construction and rescue. Hum Gene Ther 2001; 12: 643-657.
-
(2001)
Hum Gene Ther
, vol.12
, pp. 643-657
-
-
Hillgenberg, M.1
Schnieders, F.2
Loser, P.3
Strauss, M.4
-
17
-
-
0036171875
-
Generation of helper-dependent adenoviral vectors by homologous recombination
-
Toietta G, Pastore L, Cerullo V, Finegold M, Beaudet AL, Lee B. Generation of helper-dependent adenoviral vectors by homologous recombination. Mol Ther 2002; 5: 204-210.
-
(2002)
Mol Ther
, vol.5
, pp. 204-210
-
-
Toietta, G.1
Pastore, L.2
Cerullo, V.3
Finegold, M.4
Beaudet, A.L.5
Lee, B.6
-
19
-
-
12944315064
-
Optimization of the helper-dependent adenovirus system for production and potency in vivo
-
Sandig V, Youil R, Bett AJ, et al. Optimization of the helper-dependent adenovirus system for production and potency in vivo. Proc Natl Acad Sci U S A 2000; 97: 1002-1007.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 1002-1007
-
-
Sandig, V.1
Youil, R.2
Bett, A.J.3
-
20
-
-
0017710978
-
Characteristics of a human cell line transformed by DNA from human adenovirus type 5
-
Graham FL, Smiley J, Russell WC, Nairn R. Characteristics of a human cell line transformed by DNA from human adenovirus type 5. J Gen Virol 1977; 36: 59-74.
-
(1977)
J Gen Virol
, vol.36
, pp. 59-74
-
-
Graham, F.L.1
Smiley, J.2
Russell, W.C.3
Nairn, R.4
-
21
-
-
0030426525
-
Production and characterization of human 293 cell lines expressing the site-specific recombinase Cre
-
Chen L, Anton M, Graham FL. Production and characterization of human 293 cell lines expressing the site-specific recombinase Cre. Somat Cell Mol Genet 1996; 22: 477-488.
-
(1996)
Somat Cell Mol Genet
, vol.22
, pp. 477-488
-
-
Chen, L.1
Anton, M.2
Graham, F.L.3
-
22
-
-
0029086344
-
Intratumoral injection of an adenovirus expressing interleukin 2 induces regression and immunity in a murine breast cancer model
-
Addison CL, Braciak T, Ralston R, Muller WJ, Gauldie J, Graham FL. Intratumoral injection of an adenovirus expressing interleukin 2 induces regression and immunity in a murine breast cancer model. Proc Natl Acad Sci U S A 1995; 92: 8522-8526.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 8522-8526
-
-
Addison, C.L.1
Braciak, T.2
Ralston, R.3
Muller, W.J.4
Gauldie, J.5
Graham, F.L.6
-
23
-
-
0035988782
-
Preparation of helper-dependent adenoviral vectors
-
Ng P, Parks RJ, Graham FL. Preparation of helper-dependent adenoviral vectors. Methods Mol Med 2002; 69: 371-388.
-
(2002)
Methods Mol Med
, vol.69
, pp. 371-388
-
-
Ng, P.1
Parks, R.J.2
Graham, F.L.3
-
24
-
-
0015847039
-
A new technique for the assay of infectivity of human adenovirus 5 DNA
-
Graham FL, van der Eb AJ. A new technique for the assay of infectivity of human adenovirus 5 DNA. Virology 1973; 52: 456-467.
-
(1973)
Virology
, vol.52
, pp. 456-467
-
-
Graham, F.L.1
van der Eb, A.J.2
-
25
-
-
0032827780
-
Use of helper-dependent adenoviral vectors of alternative serotypes permits repeat vector administration
-
Parks R, Evelegh C, Graham F. Use of helper-dependent adenoviral vectors of alternative serotypes permits repeat vector administration. Gene Ther 1999; 6: 1565-1573.
-
(1999)
Gene Ther
, vol.6
, pp. 1565-1573
-
-
Parks, R.1
Evelegh, C.2
Graham, F.3
-
26
-
-
0036223698
-
Cre levels limit packaging signal excision efficiency in the Cre/loxP helper-dependent adenoviral vector system
-
Ng P, Evelegh C, Cummings D, Graham FL. Cre levels limit packaging signal excision efficiency in the Cre/loxP helper-dependent adenoviral vector system. J Virol 2002; 76: 4181-4189.
-
(2002)
J Virol
, vol.76
, pp. 4181-4189
-
-
Ng, P.1
Evelegh, C.2
Cummings, D.3
Graham, F.L.4
-
27
-
-
0026587657
-
Induction of mammary tumors by expression of polyomavirus middle T oncogene: A transgenic mouse model for metastatic disease
-
Guy CT, Cardiff RD, Muller WJ. Induction of mammary tumors by expression of polyomavirus middle T oncogene: a transgenic mouse model for metastatic disease. Mol Cell Biol 1992; 12: 954-961.
-
(1992)
Mol Cell Biol
, vol.12
, pp. 954-961
-
-
Guy, C.T.1
Cardiff, R.D.2
Muller, W.J.3
-
28
-
-
0034650401
-
Prostate-specific antigen promoter/enhancer driven gene therapy for prostate cancer: Construction and testing of a tissue-specific adenovirus vector
-
Latham JP, Searle PF, Mautner V, James ND. Prostate-specific antigen promoter/enhancer driven gene therapy for prostate cancer: construction and testing of a tissue-specific adenovirus vector. Cancer Res 2000; 60: 334-341.
-
(2000)
Cancer Res
, vol.60
, pp. 334-341
-
-
Latham, J.P.1
Searle, P.F.2
Mautner, V.3
James, N.D.4
-
29
-
-
0033541593
-
Augmentation of melanoma-specific gene expression using a tandem melanocyte-specific enhancer results in increased cytotoxicity of the purine nucleoside phosphorylase gene in melanoma
-
Park BJ, Brown CK, Hu Y, et al. Augmentation of melanoma-specific gene expression using a tandem melanocyte-specific enhancer results in increased cytotoxicity of the purine nucleoside phosphorylase gene in melanoma. Hum Gene Ther 1999; 10: 889-898.
-
(1999)
Hum Gene Ther
, vol.10
, pp. 889-898
-
-
Park, B.J.1
Brown, C.K.2
Hu, Y.3
-
30
-
-
0029730701
-
Transcriptional targeting of recombinant adenoviruses to human and murine melanoma cells
-
Siders WM, Halloran PJ, Fenton RG. Transcriptional targeting of recombinant adenoviruses to human and murine melanoma cells. Cancer Res 1996; 56: 5638-5646.
-
(1996)
Cancer Res
, vol.56
, pp. 5638-5646
-
-
Siders, W.M.1
Halloran, P.J.2
Fenton, R.G.3
-
31
-
-
0030056285
-
Mammaglobin, a mammary-specific member of the uteroglobin gene family, is overexpressed in human breast cancer
-
Watson MA, Fleming TP. Mammaglobin, a mammary-specific member of the uteroglobin gene family, is overexpressed in human breast cancer. Cancer Res 1996; 56: 860-865.
-
(1996)
Cancer Res
, vol.56
, pp. 860-865
-
-
Watson, M.A.1
Fleming, T.P.2
-
32
-
-
0002559220
-
Adenovirus vectors
-
Friedmann T (ed). Cold Spring Harbor Laboratory Press: San Diego, CA
-
Wivel NA, Gao G-P, Wilson JM. Adenovirus vectors. In The Development of Human Gene Therapy, Friedmann T (ed). Cold Spring Harbor Laboratory Press: San Diego, CA, 1999; 87-110.
-
(1999)
The Development of Human Gene Therapy
, pp. 87-110
-
-
Wivel, N.A.1
Gao, G.-P.2
Wilson, J.M.3
-
33
-
-
0031049699
-
Persistence in muscle of an adenoviral vector that lacks all viral genes
-
Chen HH, Mack LM, Kelly R, Ontell M, Kochanek S, Clemens PR. Persistence in muscle of an adenoviral vector that lacks all viral genes. Proc Natl Acad Sci USA 1997; 94: 1645-1650.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 1645-1650
-
-
Chen, H.H.1
Mack, L.M.2
Kelly, R.3
Ontell, M.4
Kochanek, S.5
Clemens, P.R.6
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