The human SCGB2A2 (Mammaglobin-1) promoter/enhancer in a helper-dependent adenovirus vector directs high levels of transgene expression in mammary carcinoma cells but not in normal nonmammary cells

Molecular Therapy

Volumn 10, Issue 4, 2004, Pages 758-767

  Shi, Chang Xin ^a   Long, Michael A ^a,b   Liu, Limin ^a   Graham, Frank L ^a   Gauldie, Jack ^a   Hitt, Mary M ^a,c  

^a MCMASTER UNIVERSITY   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; DNA FRAGMENT; MAMMAGLOBIN;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BREAST CARCINOMA; CARCINOMA CELL; CONTROLLED STUDY; EMBRYO; GENE DELETION; GENE EXPRESSION; GENE IDENTIFICATION; GENE TRANSFER; GENETIC CODE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VITRO STUDY; MOLECULAR CLONING; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PROMOTER REGION; TRANSGENE;

ADENOVIRIDAE; ANIMALS; BASE PAIRING; BREAST NEOPLASMS; CARCINOMA; CELL LINE, TUMOR; ENHANCER ELEMENTS (GENETICS); FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE THERAPY; GENES, REPORTER; GENETIC VECTORS; HELPER VIRUSES; HUMANS; LUCIFERASES; MAMMARY NEOPLASMS, EXPERIMENTAL; MICE; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; NEOPLASM PROTEINS; PROMOTER REGIONS (GENETICS); SEQUENCE DELETION; UTEROGLOBIN;

ADENOVIRIDAE;

EID: 4644305734     PISSN: 15250016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ymthe.2004.06.849     Document Type: Article

References (52)

1. L.M. Anderson et al. Adenovirus-mediated tissue-targeted expression of the HSVtk gene for the treatment of breast cancer Gene Ther. 6 1999 854-864
2. J. Webster R.M. Wallace A.J. Clark C.B. Whitelaw Tissue-specific, temporally regulated expression mediated by the proximal ovine beta-lactoglobulin promoter in transgenic mice Cell. Mol. Biol. Res. 41 1995 11-15
3. A. Stacey et al. Use of double-replacement gene targeting to replace the murine alpha-lactalbumin gene with its human counterpart in embryonic stem cells and mice Mol. Cell. Biol. 14 1994 1009-1016
4. Y. Manome M. Abe M.F. Hagen H.A. Fine D.W. Kufe Enhancer sequences of the DF3 gene regulate expression of the herpes simplex virus thymidine kinase gene and confer sensitivity of human breast cancer cells to ganciclovir Cancer Res. 54 1994 5408-5413
5. L. Chen et al. Breast cancer selective gene expression and therapy mediated by recombinant adenoviruses containing the DF3/MUC1 promoter J. Clin. Invest. 96 1995 2775-2782
6. M.M. Katabi H.L. Chan S.E. Karp G. Batist Hexokinase type II: a novel tumor-specific promoter for gene-targeted therapy differentially expressed and regulated in human cancer cells Hum. Gene Ther. 10 1999 155-164
7. Y.S. Cong J. Wen S. Bacchetti The human telomerase catalytic subunit hTERT: organization of the gene and characterization of the promoter Hum. Mol. Genet. 8 1999 137-142
8. D.P. Hollywood H.C. Hurst A novel transcription factor, OB2-1, is required for overexpression of the proto-oncogene c-erbB-2 in mammary tumour lines 12 1993 2369-2375
9. D.J. Slamon et al. Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer Science 244 1989 707-712
10. S.B. Ho et al. Heterogeneity of mucin gene expression in normal and neoplastic tissues Cancer Res. 53 1993 641-651
11. S. Kamoshida Y. Tsutsumi Expression of MUC-1 glycoprotein in plasma cells, follicular dendritic cells, myofibroblasts and perineurial cells: immunohistochemical analysis using three monoclonal antibodies Pathol. Int. 48 1998 776-785
12. T.S. Tsao R. Burcelin M.J. Charron Regulation of hexokinase II gene expression by glucose flux in skeletal muscle J. Biol. Chem. 271 1996 14959-14963
13. M.F. Press C. Cordon-Cardo D.J. Slamon Expression of the HER-2/neu proto-oncogene in normal human adult and fetal tissues Oncogene 5 1990 953-962
14. S. Ramakrishnan U. Eppenberger H. Mueller Y. Shinkai R. Narayanan Expression profile of the putative catalytic subunit of the telomerase gene Cancer Res. 58 1998 622-625
15. M.A. Watson T.P. Fleming Isolation of differentially expressed sequence tags from human breast cancer Cancer Res. 54 1994 4598-4602
16. T.P. Fleming M.A. Watson Mammaglobin, a breast-specific gene, and its utility as a marker for breast cancer Ann. N. Y. Acad. Sci. 923 2000 78-89
17. M. Ooka et al. Selection of mRNA markers for detection of lymph node micrometastases in breast cancer patients Oncol. Rep. 7 2000 561-566
18. K. Grunewald et al. Mammaglobin gene expression: a superior marker of breast cancer cells in peripheral blood in comparison to epidermal-growth-factor receptor and cytokeratin-19 Lab. Invest. 80 2000 1071-1077
19. R.L. Houghton et al. Transcriptional complementarity in breast cancer: application to detection of circulating tumor cells Mol. Diagn. 6 2001 79-91
20. M.A. Watson T.P. Fleming Mammaglobin, a mammary-specific member of the uteroglobin gene family, is overexpressed in human breast cancer Cancer Res. 56 1996 860-865
21. B.K. Zehentner D. Carter Mammaglobin: a candidate diagnostic marker for breast cancer Clin. Biochem. 37 2004 249-257
22. M.A. Watson C. Darrow D.B. Zimonjic N.C. Popescu T.P. Fleming Structure and transcriptional regulation of the human mammaglobin gene, a breast cancer associated member of the uteroglobin gene family localized to chromosome 11q13 Oncogene 16 1998 817-824
23. M.M. Hitt R.J. Parks F.L. Graham Structure and genetic organization of adenovirus vectors. In: The Development of Human Gene Therapy T. Friedmann, Ed. 1999 Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY 61-86
24. C.X. Shi M. Hitt P. Ng F.L. Graham Superior tissue-specific expression from tyrosinase and prostate-specific antigen promoters/enhancers in helper-dependent compared with first-generation adenoviral vectors Hum. Gene Ther. 13 2002 211-224
25. F.L. Graham A.J. van der Eb A new technique for the assay of infectivity of human adenovirus 5 DNA Virology 52 1973 456-467
26. K. Quandt K. Frech H. Karas E. Wingender T. Werner MatInd and MatInspector: new fast and versatile tools for detection of consensus matches in nucleotide sequence data Nucl. Acids Res. 23 1995 4878-4884
27. C.Y. Chen R.J. Schwartz Identification of novel DNA binding targets and regulatory domains of a murine tinman homeodomain factor, nkx-2.5 J. Biol. Chem. 270 1995 15628-15633
28. S. Pierrou M. Hellqvist L. Samuelsson S. Enerback P. Carlsson Cloning and characterization of seven human forkhead proteins: binding site specificity and DNA bending 13 1994 5002-5012
29. M.J. Klemsz S.R. McKercher A. Celada C. Van Beveren R.A. Maki The macrophage and B cell-specific transcription factor PU.1 is related to the ets oncogene Cell 61 1990 113-124
30. S.P. Hunger R. Brown M.L. Cleary DNA-binding and transcriptional regulatory properties of hepatic leukemia factor (HLF) and the t(17;19) acute lymphoblastic leukemia chimera E2A-HLF Mol. Cell. Biol. 14 1994 5986-5996
31. A. Shrivastava K. Calame An analysis of genes regulated by the multi-functional transcriptional regulator Yin Yang-1 Nucl. Acids Res. 22 1994 5151-5155
32. F. Tronche M. Yaniv HNF1, a homeoprotein member of the hepatic transcription regulatory network Bioessays 14 1992 579-587
33. J.D. Fraser V. Martinez R. Straney M.R. Briggs DNA binding and transcription activation specificity of hepatocyte nuclear factor 4 Nucl. Acids Res. 26 1998 2702-2707
34. R. Lin P. Genin Y. Mamane J. Hiscott Selective DNA binding and association with the CREB binding protein coactivator contribute to differential activation of alpha/beta interferon genes by interferon regulatory factors 3 and 7 Mol. Cell. Biol. 20 2000 6342-6353
35. P. Denny S. Swift F. Connor A. Ashworth An SRY-related gene expressed during spermatogenesis in the mouse encodes a sequence-specific DNA-binding protein EMBO J. 11 1992 3705-3712
36. E.J. Bellefroid et al. X-MyT1, a Xenopus C2HC-type zinc finger protein with a regulatory function in neuronal differentiation Cell 87 1996 1191-1202
37. J.L. Imler et al. Targeting cell-specific gene expression with an adenovirus vector containing the lacZ gene under the control of the CFTR promoter Gene Ther. 3 1996 49-58
38. C.J. Ring J.D. Harris H.C. Hurst N.R. Lemoine Suicide gene expression induced in tumour cells transduced with recombinant adenoviral, retroviral and plasmid vectors containing the ERBB2 promoter Gene Ther. 3 1996 1094-1103
39. D.S. Steinwaerder A. Lieber Insulation from viral transcriptional regulatory elements improves inducible transgene expression from adenovirus vectors in vitro and in vivo Gene Ther. 7 2000 556-567
40. G. Vassaux H.C. Hurst N.R. Lemoine Insulation of a conditionally expressed transgene in an adenoviral vector Gene Ther. 6 1999 1192-1197
41. Q. Shi Y. Wang R. Worton Modulation of the specificity and activity of a cellular promoter in an adenoviral vector Hum. Gene Ther. 8 1997 403-410
42. J.L. Bramson M. Hitt J. Gauldie F.L. Graham Pre-existing immunity to adenovirus does not prevent tumor regression following intratumoral administration of a vector expressing IL-12 but inhibits virus dissemination Gene Ther. 4 1997 1069-1076
43. F.L. Graham J. Smiley W.C. Russell R. Nairn Characteristics of a human cell line transformed by DNA from human adenovirus type 5 J. Gen. Virol. 36 1977 59-74
44. L. Chen M. Anton F.L. Graham Production and characterization of human 293 cell lines expressing the site-specific recombinase Cre Somatic Cell Mol. Genet. 22 1996 477-488
45. C.L. Addison et al. Intratumoral injection of an adenovirus expressing interleukin 2 induces regression and immunity in a murine breast cancer model Proc. Natl. Acad. Sci. USA 92 1995 8522-8526
46. K. Osoegawa et al. An improved approach for construction of bacterial artificial chromosome libraries Genomics 52 1998 1-8
47. P. Ng F.L. Graham Simple and efficient methods for construction of first generation adenoviral vectors. In: Gene Therapy Protocols, J.R. Morgan, Ed. 2001 Humana Press, Clifton, NJ
48. V. Sandig et al. Optimization of the helper-dependent adenovirus system for production and potency in vivo Proc. Natl. Acad. Sci. USA 97 2000 1002-1007
49. R.J. Parks F.L. Graham A helper-dependent system for adenovirus vector production helps define a lower limit for efficient DNA packaging J. Virol. 71 1997 3293-3298
50. R.J. Parks et al. A helper-dependent adenovirus vector system: removal of helper virus by Cre-mediated excision of the viral packaging signal Proc. Natl. Acad. Sci. USA 93 1996 13565-13570
51. P. Ng R.J. Parks F.L. Graham Methods for the preparation of helper-dependent adenoviral vectors. In: Gene Therapy Protocols, J.R. Morgan, Ed. 2001 Humana Press, Clifton, NJ
52. C.T. Guy R.D. Cardiff W.J. Muller Induction of mammary tumors by expression of polyomavirus middle T oncogene: a transgenic mouse model for metastatic disease Mol. Cell. Biol. 12 1992 954-961