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Volumn 7, Issue 2, 2006, Pages 39-46

Metabolomics - A 'systems' contribution to pharmaceutical discovery and drug development

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ANTILIPEMIC AGENT; CYCLOOXYGENASE 2 INHIBITOR; IBUPROFEN; IMATINIB; NAPROXEN; NEW DRUG; PROTEOME; TRANSCRIPTOME;

EID: 33646233206     PISSN: 14694344     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (8)

References (20)
  • 1
    • 23044491985 scopus 로고    scopus 로고
    • Is declining innovation in the pharmaceutical industry a myth?
    • Schmid, EF, Smith, DA. Is declining innovation in the pharmaceutical industry a myth? Drug Discovery Today 1, 1031-1039 (2005).
    • (2005) Drug Discovery Today , vol.1 , pp. 1031-1039
    • Schmid, E.F.1    Smith, D.A.2
  • 2
    • 17144416546 scopus 로고    scopus 로고
    • Consolidation in the global biopharma sector
    • Mehta, V. Consolidation in the global biopharma sector. Genetic Engineering News 25, 48-49 (2005).
    • (2005) Genetic Engineering News , vol.25 , pp. 48-49
    • Mehta, V.1
  • 6
    • 0041864127 scopus 로고    scopus 로고
    • In vivo measurement of fluxes through metabolic pathways; the missing link in functional genomics and pharmaceutical research
    • Hellerstein, MK. In vivo measurement of fluxes through metabolic pathways; the missing link in functional genomics and pharmaceutical research. Annu Rev Nutr 23, 379-402 (2003).
    • (2003) Annu Rev Nutr , vol.23 , pp. 379-402
    • Hellerstein, M.K.1
  • 12
    • 24044519089 scopus 로고    scopus 로고
    • Hepatic de novo lipogenesis in stable low-birth-weight infants during exclusive breast milk feedings and during parenteral nutrition
    • Garg, M, Bassilian, S, Bell, C, Lee, S, Lee, WNP. Hepatic de novo lipogenesis in stable low-birth-weight infants during exclusive breast milk feedings and during parenteral nutrition. J Parenter Enteral Nutr 29, 81-86 (2005).
    • (2005) J Parenter Enteral Nutr , vol.29 , pp. 81-86
    • Garg, M.1    Bassilian, S.2    Bell, C.3    Lee, S.4    Lee, W.N.P.5
  • 14
    • 0011039421 scopus 로고    scopus 로고
    • A revolution in R&D: How genomics and genetics are transforming the biopharmaceutical industry
    • Boston Consulting Group, Boston, MA USA
    • Tollman, P, Guy, P, Altshuler, J, Flanagan, A, Steiner, M. A revolution in R&D: How genomics and genetics are transforming the biopharmaceutical industry. Boston Consulting Group, Boston, MA USA (2001) http://www.bcg.com/publications/files/ eng_genomicsgenetics_rep_11-01.pdf
    • (2001)
    • Tollman, P.1    Guy, P.2    Altshuler, J.3    Flanagan, A.4    Steiner, M.5
  • 15
    • 33646255567 scopus 로고    scopus 로고
    • Differential effects of a soluble epoxide hydrolase inhibitor and PPAR-alpha and -gamma agonists on mouse plasma lipid profiles
    • Poster presentation at Metabolomics 2005: The First Annual International Conference of the Metabolomics Society, Tsuruoka City, Japan, June
    • Wheelock, CE, Schmelzer, K, Watkins, S, Hammock, BD, Newman, JW. Differential effects of a soluble epoxide hydrolase inhibitor and PPAR-alpha and -gamma agonists on mouse plasma lipid profiles. Poster presentation at Metabolomics 2005: The First Annual International Conference of the Metabolomics Society, Tsuruoka City, Japan, June 2005.
    • (2005)
    • Wheelock, C.E.1    Schmelzer, K.2    Watkins, S.3    Hammock, B.D.4    Newman, J.W.5
  • 16
    • 33644776521 scopus 로고    scopus 로고
    • MitoNEET agonist PNU-91325 increases fatty acid synthesis from glucose and mitochondrial long chain fatty acid degradation; A comparative tracer-based metabolomics study with rosiglitazone and pioglitazone in HepG2 cells
    • in press
    • Harrigan, GG, Colca, JR, Szalma, S, Boros, LG. MitoNEET agonist PNU-91325 increases fatty acid synthesis from glucose and mitochondrial long chain fatty acid degradation; A comparative tracer-based metabolomics study with rosiglitazone and pioglitazone in HepG2 cells. Metabolomics, in press (2006).
    • (2006) Metabolomics
    • Harrigan, G.G.1    Colca, J.R.2    Szalma, S.3    Boros, L.G.4
  • 20
    • 2942724415 scopus 로고    scopus 로고
    • The omega-3 index: A new risk factor for death from coronary heart disease?
    • Harris, WS, von Schacky, C. The omega-3 index: a new risk factor for death from coronary heart disease? Prev Med 39, 212-220 (2004).
    • (2004) Prev Med , vol.39 , pp. 212-220
    • Harris, W.S.1    von Schacky, C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.