SNRPN methylation patterns in germ cell tumors as a reflection of primordial germ cell development

Genes Chromosomes and Cancer

Volumn 32, Issue 4, 2001, Pages 342-352

  Bussey, Kimberly J ^a,e   Lawce, Helen J ^a   Himoe, Eleanor ^a,e   Shu, Xiao Ou ^b,e   Heerema, Nyla A ^c,e   Perlman, Elizabeth J ^d,e   Olson, Susan B ^a   Magenis, R Ellen ^a,e,f  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b VANDERBILT UNIVERSITY   (United States)

^c PARKER HUGHES INSTITUTE   (United States)

^d JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e CHILDREN S ONCOLOGY GROUP   (United States)

^f OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT; SMALL NUCLEAR RIBONUCLEOPROTEIN ASSOCIATED POLYPEPTIDE N; UNCLASSIFIED DRUG;

5' UNTRANSLATED REGION; ADOLESCENT; ADULT; ARTICLE; CELL MATURATION; CHILD; CONTROLLED STUDY; CYTOGENETICS; DNA METHYLATION; FEMALE; GENE EXPRESSION; GENE LOCUS; GENOME IMPRINTING; GERM CELL TUMOR; HUMAN; HUMAN CELL; HUMAN TISSUE; INFANT; MALE; MARKER GENE; PRIMORDIAL GERM CELL; PRIORITY JOURNAL;

ADOLESCENT; ADULT; AUTOANTIGENS; CHILD; CHILD, PRESCHOOL; DNA METHYLATION; DNA, NEOPLASM; FEMALE; GENOMIC IMPRINTING; GERM CELLS; GERMINOMA; HUMANS; INFANT; INFANT, NEWBORN; MALE; RIBONUCLEOPROTEINS, SMALL NUCLEAR; TUMOR CELLS, CULTURED;

EID: 0035169889     PISSN: 10452257     EISSN: None     Source Type: Journal    
DOI: 10.1002/gcc.1199     Document Type: Article

References (37)

1. Chromosome abnormalities of eighty-one pediatric germ cell tumors: Sex-, age-, site-, and histopathology-related differences - A Children's Cancer Group study
2. Chromosome 1 and chromosome 12 abnormalities in pediatric germ cell tumors by interphase FISH
3. Similar molecular deletions on chromosome 15q11.2 are encountered in both the Prader-Willi and Angelman syndromes
4. Maternal methylation imprints on human chromosome 15 are established during or after fertilization
5. Presence of clone-specific antigen receptor gene rearrangements at birth indicates an in utero origin of diverse types of early childhood acute lymphoblastic leukemia
6. In utero rearrangements in the trithorax-related oncogene in infant leukaemias
7. Monoclonal origin of concordant T-cell malignancy in identical twins
8. Fetal origins of the TEL-AML 1 fusion gene in identical twins with leukemia
9. Backtracking leukemia to birth: Identification of clonotypic gene fusion sequences in neonatal blood spots
10. Clonal, nonconstitutional rearrangements of the MLL gene in infant twins with acute lymphoblastic leukemia: In utero chromosome rearrangement of 11q23
11. Gene structure. DNA methylation, and imprinted expression of the human SNRPN gene
12. Imprinted expression of SNRPN in human preimplantation embryos
13. Clinical heterogeneity associated with deletions in the long arm of chromosome 15: Report of 3 new cases and their possible genetic significance
14. Angelman and Prader-Willi syndromes share a common chromosome 15 deletion but differ in parental origin of the deletion
15. Analysis of parent of origin specific DNA methylation at SNRPN and PW71 in tissues: Implication for prenatal diagnosis
16. Maternal imprinting of the mouse Snrpn gene and conserved linkage homology with the human Prader-Willi syndrome region
17. Is Angelman syndrome an alternate result of del(15)(q11ql3)?
18. Comparison of the 15q deletions in Prader-Willi and Angelman syndromes: Specific regions, extent of deletions, parental origin, and clinical consequences
19. Equivalent parental distribution of frequently lost alleles and biallelic expression of the H19 gene in human testicular germ cell tumors
20. Methylation imprinting of H19 and SNRPN in human benign ovarian teratomas
21. Coexistence of lymphoblastic and monoblastic populations with identical mixed lineage leukemia gene rearrangements and shared immunoglobulin heavy chain rearrangements in leukemia developed in utero
22. Genetic imprinting suggested by maternal heterodisomy in non-deletion Prader-Willi syndrome
23. Altered imprinting of the H19 and insulin-like growth factor II genes in testicular tumors
24. Human chromosome variation: The discriminatory power of Q-band heteromorphism (variant) analysis in distinguishing between individuals, with specific application to cases of questionable paternity
25. Cytogenetic darkroom magic: Now you see them, now you don't
26. Maternal imprinting of human SNRPN, a gene deleted in Prader-Willi syndrome
27. Identical cytogenetic clones and clonal evolution in pediatric monozygotic twins with acute mycloid leukemia: Presymptomatic disease detection by interphase fluorescence in situ hybridization and review of the literature
28. Genomic imprinting of H19 and insulin-like growth factor-2 in pediatric germ cell tumors
29. Structure of the imprinted mouse Snrpn gene and establishment of its parentalspecific methylation pattern
30. Biallelic expression of imprinted genes in the mouse germ line: Implications for erasure, establishment, and mechanisms of genomic imprinting
31. Allele-specific expression and total expression levels of imprinted genes during early mouse development: Implications for imprinting mechanisms
32. The impact of imprinting: Prader-Willi syndrome resulting from chromosome translocation, recombination, and nondisjunction
33. Biallelic expression of the H19 and IGF2 genes in human testicular germ cell tumors
34. Unique expression patterns of H19 in human testicular cancers of different etiology
35. Predominance of fetal type DJH joining in young children with B precursor lymphoblastic leukemia as evidence for an in utero transforming event
36. Prenatal origin of acute lymphoblastic leukaemia in children
37. Protracted and variable latency of acute lymphoblastic leukemia after TEL-AML1 gene fusion in utero