-
1
-
-
0037041420
-
Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases
-
Bucciantini, M., E. Giannoni, F. Chiti, F. Baroni, L. Formigli, J. Zurdo, N. Taddei, G. Ramponi, C. M. Dobson, and M. Stefani. 2002. Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases. Nature. 416:507-511.
-
(2002)
Nature
, vol.416
, pp. 507-511
-
-
Bucciantini, M.1
Giannoni, E.2
Chiti, F.3
Baroni, F.4
Formigli, L.5
Zurdo, J.6
Taddei, N.7
Ramponi, G.8
Dobson, C.M.9
Stefani, M.10
-
2
-
-
0032516077
-
Definition of amide protection factors for early kinetic intermediates in protein folding
-
Houry, W. A., J. M. Sauder, H. Roder, and H. A. Scheraga. 1998. Definition of amide protection factors for early kinetic intermediates in protein folding. Proc. Natl. Acad. Sci. USA. 95:4299-4302.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 4299-4302
-
-
Houry, W.A.1
Sauder, J.M.2
Roder, H.3
Scheraga, H.A.4
-
3
-
-
0032502803
-
Molecular mechanisms for cooperative folding of proteins
-
Hao, M. H., and H. A. Scheraga. 1998. Molecular mechanisms for cooperative folding of proteins. J. Mol. Biol. 277:973-983.
-
(1998)
J. Mol. Biol.
, vol.277
, pp. 973-983
-
-
Hao, M.H.1
Scheraga, H.A.2
-
4
-
-
0347357617
-
Protein folding and misfolding
-
Dobson, C. M. 2003. Protein folding and misfolding. Nature. 426:884-890.
-
(2003)
Nature
, vol.426
, pp. 884-890
-
-
Dobson, C.M.1
-
6
-
-
0033613236
-
Equilibria and kinetics of folding of gelsolin domain 2 and mutants involved in familial amyloidosis-Finnish type
-
Isaacson, R. L., A. G. Weeds, and A. R. Fersht. 1999. Equilibria and kinetics of folding of gelsolin domain 2 and mutants involved in familial amyloidosis-Finnish type. Proc. Natl. Acad. Sci. USA. 96:11247-11252.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 11247-11252
-
-
Isaacson, R.L.1
Weeds, A.G.2
Fersht, A.R.3
-
7
-
-
0035961329
-
The structural basis of protein folding and its links with human disease
-
Dobson, C. M. 2001. The structural basis of protein folding and its links with human disease. Philos. Trans. R. Soc. Lond. B Biol. Sci. 356:133-145.
-
(2001)
Philos. Trans. R. Soc. Lond. B Biol. Sci.
, vol.356
, pp. 133-145
-
-
Dobson, C.M.1
-
8
-
-
0030609125
-
Aβ25-35 induces rapid lysis of red blood cells: Contrast with Aβ1-42 and examination of underlying mechanisms
-
Mattson, M. P., J. G. Begley, R. J. Mark, and K. Furukawa. 1997. Aβ25-35 induces rapid lysis of red blood cells: contrast with Aβ1-42 and examination of underlying mechanisms. Brain Res. 771:147-153.
-
(1997)
Brain Res.
, vol.771
, pp. 147-153
-
-
Mattson, M.P.1
Begley, J.G.2
Mark, R.J.3
Furukawa, K.4
-
9
-
-
0027447286
-
Neurodegeneration induced by β-amyloid peptides in vitro: The role of peptide assembly state
-
Pike, C. J., D. Burdick, A. J. Walencewicz, C. G. Glabe, and C. W. Cotman. 1993. Neurodegeneration induced by β-amyloid peptides in vitro: the role of peptide assembly state. J. Neurosci. 13:1676-1687.
-
(1993)
J. Neurosci.
, vol.13
, pp. 1676-1687
-
-
Pike, C.J.1
Burdick, D.2
Walencewicz, A.J.3
Glabe, C.G.4
Cotman, C.W.5
-
10
-
-
0024990330
-
Neurotrophic and neurotoxic effects of amyloid β protein: Reversal by tachykinin neuropeptides
-
Yankner, B. A., L. K. Duffy, and D. A. Kirschner. 1990. Neurotrophic and neurotoxic effects of amyloid β protein: reversal by tachykinin neuropeptides. Science. 250:279-282.
-
(1990)
Science
, vol.250
, pp. 279-282
-
-
Yankner, B.A.1
Duffy, L.K.2
Kirschner, D.A.3
-
11
-
-
21544465581
-
An alternative interpretation of the amyloid Aβ hypothesis with regard to the pathogenesis of Alzheimer's disease
-
Marchesi, V. T. 2005. An alternative interpretation of the amyloid Aβ hypothesis with regard to the pathogenesis of Alzheimer's disease. Proc. Natl. Acad. Sci. USA. 102:9093-9098.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 9093-9098
-
-
Marchesi, V.T.1
-
12
-
-
0037130174
-
Neurodegenerative disease: Amyloid pores from pathogenic mutations
-
Lashuel, H. A., D. Hartley, B. M. Petre, T. Walz, and P. T. Lansbury Jr. 2002. Neurodegenerative disease: amyloid pores from pathogenic mutations. Nature. 418:291.
-
(2002)
Nature
, vol.418
, pp. 291
-
-
Lashuel, H.A.1
Hartley, D.2
Petre, B.M.3
Walz, T.4
Lansbury Jr., P.T.5
-
13
-
-
0035159553
-
Amyloid β protein forms ion channels: Implications for Alzheimer's disease pathophysiology
-
Lin, H., R. Bhatia, and R. Lal. 2001. Amyloid β protein forms ion channels: implications for Alzheimer's disease pathophysiology. FASEB J. 15:2433-2444.
-
(2001)
FASEB J.
, vol.15
, pp. 2433-2444
-
-
Lin, H.1
Bhatia, R.2
Lal, R.3
-
14
-
-
0035997234
-
The channel hypothesis of Alzheimer's disease: Current status
-
Kagan, B. L., Y. Hirakura, R. Azimov, R. Azimova, and M. C. Lin. 2002. The channel hypothesis of Alzheimer's disease: current status. Peptides. 23:1311-1315.
-
(2002)
Peptides
, vol.23
, pp. 1311-1315
-
-
Kagan, B.L.1
Hirakura, Y.2
Azimov, R.3
Azimova, R.4
Lin, M.C.5
-
15
-
-
9144236872
-
Structural analysis of amyloid β peptide fragment (25-35) in different microenvironments
-
Shanmugam, G., and R. Jayakumar. 2004. Structural analysis of amyloid β peptide fragment (25-35) in different microenvironments. Biopolymers. 76:421-434.
-
(2004)
Biopolymers
, vol.76
, pp. 421-434
-
-
Shanmugam, G.1
Jayakumar, R.2
-
16
-
-
3843139571
-
Solution structure of amyloid β-peptide (25-35) in different media
-
D'Ursi, A. M., M. R. Armenante, R. Guerrini, S. Salvadori, G. Sorrentino, and D. Picone. 2004. Solution structure of amyloid β-peptide (25-35) in different media. J. Med. Chem. 47:4231-4238.
-
(2004)
J. Med. Chem.
, vol.47
, pp. 4231-4238
-
-
D'Ursi, A.M.1
Armenante, M.R.2
Guerrini, R.3
Salvadori, S.4
Sorrentino, G.5
Picone, D.6
-
17
-
-
0037173120
-
Probing solvent accessibility of amyloid fibrils by solution NMR spectroscopy
-
Ippel, J. H., A. Olofsson, J. Schleucher, E. Lundgren, and S. S. Wijmenga. 2002. Probing solvent accessibility of amyloid fibrils by solution NMR spectroscopy. Proc. Natl. Acad. Sci. USA. 99:8648-8653.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 8648-8653
-
-
Ippel, J.H.1
Olofsson, A.2
Schleucher, J.3
Lundgren, E.4
Wijmenga, S.S.5
-
18
-
-
0035916279
-
Amyloid-induced aggregation and precipitation of soluble proteins: An electrostatic contribution of the Alzheimer's β(25-35) amyloid fibril
-
Konno, T. 2001. Amyloid-induced aggregation and precipitation of soluble proteins: an electrostatic contribution of the Alzheimer's β(25-35) amyloid fibril. Biochemistry. 40:2148-2154.
-
(2001)
Biochemistry
, vol.40
, pp. 2148-2154
-
-
Konno, T.1
-
19
-
-
0033535951
-
Intermediates can accelerate protein folding
-
Wagner, C., and T. Kiefhaber. 1999. Intermediates can accelerate protein folding. Proc. Natl. Acad. Sci. USA. 96:6716-6721.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 6716-6721
-
-
Wagner, C.1
Kiefhaber, T.2
-
20
-
-
0029063717
-
The complexity and accuracy of discrete state models of protein structure
-
Park, B. H., and M. Levitt. 1995. The complexity and accuracy of discrete state models of protein structure. J. Mol. Biol. 249:493-507.
-
(1995)
J. Mol. Biol.
, vol.249
, pp. 493-507
-
-
Park, B.H.1
Levitt, M.2
-
21
-
-
0042512009
-
Energy landscape and dynamics of the β-hairpin G peptide and its isomers: Topology and sequences
-
Ma, B., and R. Nussinov. 2003. Energy landscape and dynamics of the β-hairpin G peptide and its isomers: Topology and sequences. Protein Sci. 12:1882-1893.
-
(2003)
Protein Sci.
, vol.12
, pp. 1882-1893
-
-
Ma, B.1
Nussinov, R.2
-
22
-
-
0033729617
-
A systematic study of the vibrational free energies of polypeptides in folded and random states
-
Ma, B., C. J. Tsai, and R. Nussinov. 2000. A systematic study of the vibrational free energies of polypeptides in folded and random states. Biophys. J. 79:2739-2753.
-
(2000)
Biophys. J.
, vol.79
, pp. 2739-2753
-
-
Ma, B.1
Tsai, C.J.2
Nussinov, R.3
-
23
-
-
0038792211
-
New analytic approximation to the standard molecular volume definition and its application to generalized Born calculations
-
Lee, M. S., M. Feig, F. R. Salsbury, Jr., and C. L. Brooks 3rd. 2003. New analytic approximation to the standard molecular volume definition and its application to generalized Born calculations. J. Comput. Chem. 24:1348-1356.
-
(2003)
J. Comput. Chem.
, vol.24
, pp. 1348-1356
-
-
Lee, M.S.1
Feig, M.2
Salsbury Jr., F.R.3
Brooks III, C.L.4
-
24
-
-
0034682788
-
Inhibition of toxicity in the β-amyloid peptide fragment β-(25-35) using N-methylated derivatives: A general strategy to prevent amyloid formation
-
Hughes, E., R. M. Burke, and A. J. Doig. 2000. Inhibition of toxicity in the β-amyloid peptide fragment β-(25-35) using N-methylated derivatives: a general strategy to prevent amyloid formation. J. Biol. Chem. 275:25109-25115.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 25109-25115
-
-
Hughes, E.1
Burke, R.M.2
Doig, A.J.3
-
25
-
-
0037195098
-
Stabilities and conformations of Alzheimer's β-amyloid peptide oligomers (Aβ16-22, Aβ16-35, and Aβ10-35): Sequence effects
-
Ma, B., and R. Nussinov. 2002. Stabilities and conformations of Alzheimer's β-amyloid peptide oligomers (Aβ16-22, Aβ16-35, and Aβ10-35): sequence effects. Proc. Natl. Acad. Sci. USA. 99:14126-14131.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 14126-14131
-
-
Ma, B.1
Nussinov, R.2
-
26
-
-
0034718157
-
Alzheimer's amyloid fibrils: Structure and assembly
-
Serpell, L. C. 2000. Alzheimer's amyloid fibrils: structure and assembly. Biochim. Biophys. Acta. 1502:16-30.
-
(2000)
Biochim. Biophys. Acta
, vol.1502
, pp. 16-30
-
-
Serpell, L.C.1
-
27
-
-
0027411230
-
Structure of β-crystallite assemblies formed by Alzheimer β-amyloid protein analogues: Analysis by x-ray diffraction
-
Inouye, H., P. E. Fraser, and D. A. Kirschner. 1993. Structure of β-crystallite assemblies formed by Alzheimer β-amyloid protein analogues: analysis by x-ray diffraction. Biophys. J. 64:502-519.
-
(1993)
Biophys. J.
, vol.64
, pp. 502-519
-
-
Inouye, H.1
Fraser, P.E.2
Kirschner, D.A.3
-
28
-
-
0017868338
-
Empirical predictions of protein conformation
-
Chou, P. Y., and G. D. Fasman. 1978. Empirical predictions of protein conformation. Annu. Rev. Biochem. 47:251-276.
-
(1978)
Annu. Rev. Biochem.
, vol.47
, pp. 251-276
-
-
Chou, P.Y.1
Fasman, G.D.2
-
29
-
-
0036143592
-
One-dimensional potential barrier model of protein folding with intermediates
-
Jun, B., and D. L. Weaver. 2002. One-dimensional potential barrier model of protein folding with intermediates. J. Chem. Phys. 116:418-426.
-
(2002)
J. Chem. Phys.
, vol.116
, pp. 418-426
-
-
Jun, B.1
Weaver, D.L.2
-
30
-
-
10644278760
-
In silico study of amyloid β-protein folding and oligomerization
-
Urbanc, B., L. Cruz, S. Yun, S. V. Buldyrev, G. Bitan, D. B. Teplow, and H. E. Stanley. 2004. In silico study of amyloid β-protein folding and oligomerization. Proc. Natl. Acad. Sci. USA. 101:17345-17350.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 17345-17350
-
-
Urbanc, B.1
Cruz, L.2
Yun, S.3
Buldyrev, S.V.4
Bitan, G.5
Teplow, D.B.6
Stanley, H.E.7
-
31
-
-
0346688724
-
Assembly and kinetic folding pathways of a tetrameric β-sheet complex: Molecular dynamics simulations on simplified off-lattice protein models
-
Jang, H., C. K. Hall, and Y. Zhou. 2004. Assembly and kinetic folding pathways of a tetrameric β-sheet complex: molecular dynamics simulations on simplified off-lattice protein models. Biophys. J. 86:31-49.
-
(2004)
Biophys. J.
, vol.86
, pp. 31-49
-
-
Jang, H.1
Hall, C.K.2
Zhou, Y.3
-
32
-
-
0037337271
-
Dissecting the assembly of Aβ16-22 amyloid peptides into antiparallel b sheets
-
Klimov, D. K., and D. Thirumalai. 2003. Dissecting the assembly of Aβ16-22 amyloid peptides into antiparallel b sheets. Structure. 11:295-307.
-
(2003)
Structure
, vol.11
, pp. 295-307
-
-
Klimov, D.K.1
Thirumalai, D.2
-
33
-
-
0042467550
-
Rationalization of the effects of mutations on peptide and protein aggregation rates
-
Chiti, F., M. Stefani, N. Taddei, G. Ramponi, and C. M. Dobson. 2003. Rationalization of the effects of mutations on peptide and protein aggregation rates. Nature. 424:805-808.
-
(2003)
Nature
, vol.424
, pp. 805-808
-
-
Chiti, F.1
Stefani, M.2
Taddei, N.3
Ramponi, G.4
Dobson, C.M.5
-
34
-
-
0037020259
-
Kinetic studies of amyloid β-protein fibril assembly. Differential effects of α-helix stabilization
-
Fezoui, Y., and D. B. Teplow. 2002. Kinetic studies of amyloid β-protein fibril assembly. Differential effects of α-helix stabilization. J. Biol. Chem. 277:36948-36954.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 36948-36954
-
-
Fezoui, Y.1
Teplow, D.B.2
-
35
-
-
3142568651
-
Pathway complexity of Alzheimer's β-amyloid Aβ16-22 peptide assembly
-
Santini, S., G. Wei, N. Mousseau, and P. Derreumaux. 2004. Pathway complexity of Alzheimer's β-amyloid Aβ16-22 peptide assembly. Structure. 12:1245-1255.
-
(2004)
Structure
, vol.12
, pp. 1245-1255
-
-
Santini, S.1
Wei, G.2
Mousseau, N.3
Derreumaux, P.4
-
36
-
-
18744366086
-
Protein folding pathways from replica exchange simulations and a kinetic network model
-
Andrec, M., A. K. Felts, E. Gallicchio, and R. M. Levy. 2005. Protein folding pathways from replica exchange simulations and a kinetic network model. Proc. Natl. Acad. Sci. USA. 102:6801-6806.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 6801-6806
-
-
Andrec, M.1
Felts, A.K.2
Gallicchio, E.3
Levy, R.M.4
-
37
-
-
0345133287
-
Folding a protein in a computer: An atomic description of the folding/unfolding of protein A
-
Garcia, A. E., and J. N. Onuchic. 2003. Folding a protein in a computer: an atomic description of the folding/unfolding of protein A. Proc. Natl. Acad. Sci. USA. 100:13898-13903.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 13898-13903
-
-
Garcia, A.E.1
Onuchic, J.N.2
|