Hydrogen peroxide cleavage of the prion protein generates a fragment able to initiate polymerisation of full length prion protein

International Journal of Biochemistry and Cell Biology

Volumn 38, Issue 8, 2006, Pages 1429-1440

  Abdelraheim, Salama R ^a   Královicová, Silvia ^a   Brown, David R ^a  

^a University of Bath   (United Kingdom)

Author keywords

BSE; CJD; Copper; Manganese; Oxidative stress; Prion protein; Scrapie

Indexed keywords

COPPER; HYDROGEN PEROXIDE; IRON; MAGNESIUM; MANGANESE; NICKEL; PRION PROTEIN; PROTEINASE; ZINC;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CHICKEN; MOUSE; NONHUMAN; PRION; PRION DISEASE; PROTEIN DEGRADATION; PROTEIN METABOLISM; PROTEIN MODIFICATION; PROTEIN POLYMERIZATION; TURTLE;

AMINO ACID SEQUENCE; ANIMALS; BLOTTING, WESTERN; CHICKENS; COPPER; HYDROGEN PEROXIDE; HYDROGEN-ION CONCENTRATION; HYDROLYSIS; IMMUNOBLOTTING; IRON; MANGANESE; MICE; MOLECULAR SEQUENCE DATA; MUTANT PROTEINS; PEPTIDE FRAGMENTS; POLYMERS; PRIONS; RECOMBINANT PROTEINS; TEMPERATURE; TURTLES;

TESTUDINES;

EID: 33646173434     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biocel.2006.02.007     Document Type: Article

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