AST-1, a novel ETS-box transcription factor, controls axon guidance and pharynx development in C. elegans

Developmental Biology

Volumn 293, Issue 2, 2006, Pages 403-413

  Schmid, Christina ^a   Schwarz, Valentin ^a   Hutter, Harald ^a  

^a MAX PLANCK INSTITUTE FOR MEDICAL RESEARCH   (Germany)

Author keywords

Axon guidance; Development; ETS box; Neuron; Transcription factor; Ventral cord

Indexed keywords

AST 1 PROTEIN; LIN 11 PROTEIN; NETRIN; PROTEIN; TRANSCRIPTION FACTOR ETS; UNCLASSIFIED DRUG; ZAG 1 PROTEIN;

ARTICLE; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; DEVELOPMENTAL STAGE; GENE INTERACTION; GENETICS; INTERNEURON; MORPHOGENESIS; NERVE CELL DIFFERENTIATION; NERVE FIBER GROWTH; NERVE GROWTH; NERVOUS SYSTEM; NONHUMAN; PHARYNX; PRIORITY JOURNAL; PROTEIN DOMAIN;

CAENORHABDITIS ELEGANS;

EID: 33646166078     PISSN: 00121606     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ydbio.2006.02.042     Document Type: Article

References (43)

1. Arber S., Ladle D.R., Lin J.H., Frank E., and Jessell T.M. ETS gene Er81 controls the formation of functional connections between group Ia sensory afferents and motor neurons. Cell 101 (2000) 485-498
2. Baran R., Aronoff R., and Garriga G. The C. elegans homeodomain gene unc-42 regulates chemosensory and glutamate receptor expression. Development 126 (1999) 2241-2251
3. Beitel G.J., Tuck S., Greenwald I., and Horvitz H.R. The Caenorhabditis elegans gene lin-1 encodes an ETS-domain protein and defines a branch of the vulval induction pathway. Genes Dev. 9 (1995) 3149-3162
4. Briata P., Di Blas E., Gulisano M., Mallamaci A., Iannone R., Boncinelli E., and Corte G. EMX1 homeoprotein is expressed in cell nuclei of the developing cerebral cortex and in the axons of the olfactory sensory neurons. Mech. Dev. 57 (1996) 169-180
5. Brockie P.J., Madsen D.M., Zheng Y., Mellem J., and Maricq A.V. Differential expression of glutamate receptor subunits in the nervous system of Caenorhabditis elegans and their regulation by the homeodomain protein UNC-42. J. Neurosci. 21 (2001) 1510-1522
6. Brose K., and Tessier-Lavigne M. Slit proteins: key regulators of axon guidance, axonal branching, and cell migration. Curr. Opin. Neurobiol. 10 (2000) 95-102
7. Chan S.S., Zheng H., Su M.W., Wilk R., Killeen M.T., Hedgecock E.M., and Culotti J.G. UNC-40, a C. elegans homolog of DCC (Deleted in Colorectal Cancer), is required in motile cells responding to UNC-6 netrin cues. Cell 87 (1996) 187-195
8. Charron F., and Tessier-Lavigne M. Novel brain wiring functions for classical morphogens: a role as graded positional cues in axon guidance. Development 132 (2005) 2251-2262
9. Clark S.G., and Chiu C. C. elegans ZAG-1, a Zn-finger-homeodomain protein, regulates axonal development and neuronal differentiation. Development 130 (2003) 3781-3794
10. Culotti J.G., and Merz D.C. DCC and netrins. Curr. Opin. Cell Biol. 10 (1998) 609-613
11. Drescher U. The Eph family in the patterning of neural development. Curr. Biol. 7 (1997) R799-R807
12. Durbin, R.M. (1987). Studies on the development and organisation of the nervous system of Caenorhabditis elegans, Vol. PhD, p. 150. Cambridge, UK.
13. Edgley M., D'Souza A., Moulder G., McKay S., Shen B., Gilchrist E., Moerman D., and Barstead R. Improved detection of small deletions in complex pools of DNA. Nucleic Acids Res. 30 (2002) e52
14. Eisbacher M., Holmes M.L., Newton A., Hogg P.J., Khachigian L.M., Crossley M., and Chong B.H. Protein-protein interaction between Fli-1 and GATA-1 mediates synergistic expression of megakaryocyte-specific genes through cooperative DNA binding. Mol. Cell Biol. 23 (2003) 3427-3441
15. Ferguson E.L., and Horvitz H.R. Identification and characterization of 22 genes that affect the vulval cell lineages of the nematode Caenorhabditis elegans. Genetics 110 (1985) 17-72
16. Good K., Ciosk R., Nance J., Neves A., Hill R.J., and Priess J.R. The T-box transcription factors TBX-37 and TBX-38 link GLP-1/Notch signaling to mesoderm induction in C. elegans embryos. Development 131 (2004) 1967-1978
17. Hamelin M., Zhou Y., Su M.W., Scott I.M., and Culotti J.G. Expression of the UNC-5 guidance receptor in the touch neurons of C. elegans steers their axons dorsally. Nature 364 (1993) 327-330
18. Han M., and Sternberg P.W. let-60, a gene that specifies cell fates during C. elegans vulval induction, encodes a ras protein. Cell 63 (1990) 921-931
19. Hao J.C., Yu T.W., Fujisawa K., Culotti J.G., Gengyo-Ando K., Mitani S., Moulder G., Barstead R., Tessier-Lavigne M., and Bargmann C.I. C. elegans slit acts in midline, dorsal-ventral, and anterior-posterior guidance via the SAX-3/Robo receptor. Neuron 32 (2001) 25-38
20. Hart A.H., Reventar R., and Bernstein A. Genetic analysis of ETS genes in C. elegans. Oncogene 19 (2000) 6400-6408
21. Hedgecock E.M., Culotti J.G., and Hall D.H. The unc-5, unc-6, and unc-40 genes guide circumferential migrations of pioneer axons and mesodermal cells on the epidermis in C. elegans. Neuron 4 (1990) 61-85
22. Hobert O., D'Alberti T., Liu Y., and Ruvkun G. Control of neural development and function in a thermoregulatory network by the LIM homeobox gene lin-11. J. Neurosci. 18 (1998) 2084-2096
23. Hodgkin J., and Doniach T. Natural variation and copulatory plug formation in Caenorhabditis elegans. Genetics 146 (1997) 149-164
24. Horner M.A., Quintin S., Domeier M.E., Kimble J., Labouesse M., and Mango S.E. pha-4, an HNF-3 homolog, specifies pharyngeal organ identity in Caenorhabditis elegans. Genes Dev. 12 (1998) 1947-1952
25. Hutter H. Extracellular cues and pioneers act together to guide axons in the ventral cord of C. elegans. Development 130 (2003) 5307-5318
26. Hutter H., Wacker I., Schmid C., and Hedgecock E.M. Novel genes controlling ventral cord asymmetry and navigation of pioneer axons in C. elegans. Dev. Biol. 284 (2005) 260-272
27. Jacob J., Hacker A., and Guthrie S. Mechanisms and molecules in motor neuron specification and axon pathfinding. Bioessays 23 (2001) 582-595
28. Joliot A., Trembleau A., Raposo G., Calvet S., Volovitch M., and Prochiantz A. Association of Engrailed homeoproteins with vesicles presenting caveolae-like properties. Development 124 (1997) 1865-1875
29. Kim S., and Wadsworth W.G. Positioning of longitudinal nerves in C. elegans by nidogen. Science 288 (2000) 150-154
30. Kullander K., and Klein R. Mechanisms and functions of Eph and ephrin signalling. Nat. Rev., Mol. Cell Biol. 3 (2002) 475-486
31. Ladle D.R., and Frank E. The role of the ETS gene PEA3 in the development of motor and sensory neurons. Physiol. Behav. 77 (2002) 571-576
32. Leung-Hagesteijn C., Spence A.M., Stern B.D., Zhou Y., Su M.W., Hedgecock E.M., and Culotti J.G. UNC-5, a transmembrane protein with immunoglobulin and thrombospondin type 1 domains, guides cell and pioneer axon migrations in C. elegans. Cell 71 (1992) 289-299
33. Lin J.H., Saito T., Anderson D.J., Lance-Jones C., Jessell T.M., and Arber S. Functionally related motor neuron pool and muscle sensory afferent subtypes defined by coordinate ETS gene expression. Cell 95 (1998) 393-407
34. Livet J., Sigrist M., Stroebel S., De Paola V., Price S.R., Henderson C.E., Jessell T.M., and Arber S. ETS gene Pea3 controls the central position and terminal arborization of specific motor neuron pools. Neuron 35 (2002) 877-892
35. Portereiko M.F., and Mango S.E. Early morphogenesis of the Caenorhabditis elegans pharynx. Dev. Biol. 233 (2001) 482-494
36. Postigo A.A., Sheppard A.M., Mucenski M.L., and Dean D.C. c-Myb and Ets proteins synergize to overcome transcriptional repression by ZEB. Embo J. 16 (1997) 3924-3934
37. Prochiantz A., and Joliot A. Can transcription factors function as cell-cell signalling molecules?. Nat. Rev., Mol. Cell Biol. 4 (2003) 814-819
38. Shirasaki R., and Pfaff S.L. Transcriptional codes and the control of neuronal identity. Annu. Rev. Neurosci. 25 (2002) 251-281
39. Spyropoulos D.D., Pharr P.N., Lavenburg K.R., Jackers P., Papas T.S., Ogawa M., and Watson D.K. Hemorrhage, impaired hematopoiesis, and lethality in mouse embryos carrying a targeted disruption of the Fli1 transcription factor. Mol. Cell Biol. 20 (2000) 5643-5652
40. Van Vactor D.V., and Lorenz L.J. Neural development: the semantics of axon guidance. Curr. Biol. 9 (1999) R201-R204
41. Wacker I., Schwarz V., Hedgecock E.M., and Hutter H. zag-1, a Zn-finger homeodomain transcription factor controlling neuronal differentiation and axon outgrowth in C. elegans. Development 130 (2003) 3795-3805
42. Wilkinson D.G. Multiple roles of EPH receptors and ephrins in neural development. Nat. Rev., Neurosci. 2 (2001) 155-164
43. Xue D., Finney M., Ruvkun G., and Chalfie M. Regulation of the mec-3 gene by the C. elegans homeoproteins UNC-86 and MEC-3. EMBO J. 11 (1992) 4969-4979