Gingival epithelial cells heterozygous for Toll-like receptor 4 polymorphisms Asp299Gly and Thr399Ile are hypo-responsive to Porphyromonas gingivalis

Genes and Immunity

Volumn 7, Issue 3, 2006, Pages 190-200

  Kinane, D F ^a   Shiba, H ^a,b   Stathopoulou, P G ^a   Zhao, H ^a   Lappin, D F ^a,c   Singh, A ^a   Eskan, M A ^a   Beckers, S ^d   Waigel, S ^d   Alpert, B ^a   Knudsen, T B ^a  

^a UNIVERSITY OF LOUISVILLE SCHOOL OF MEDICINE   (United States)

^b HIROSHIMA UNIVERSITY   (Japan)

^c GLASGOW DENTAL HOSPITAL AND SCHOOL   (United Kingdom)

^d University of Louisville School of Medicine   (United States)

Author keywords

Disease susceptibility; Epithelial cells; Periodontitis; Tissue culture; Toll like receptors

Indexed keywords

ASPARTIC ACID; BACTERIUM LIPOPOLYSACCHARIDE; CHEMOKINE; CYTOKINE; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GLYCINE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 3; INTERLEUKIN 6; INTERLEUKIN 8; ISOLEUCINE; MACROPHAGE INFLAMMATORY PROTEIN 3ALPHA; MESSENGER RNA; RANTES; THREONINE; TOLL LIKE RECEPTOR 10; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 5; TOLL LIKE RECEPTOR 6; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 9; TRANSCRIPTOME; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CELL CULTURE; CONTROLLED STUDY; DISEASE ASSOCIATION; EPITHELIUM CELL; GENE EXPRESSION PROFILING; GENETIC LINKAGE; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GRAM NEGATIVE BACTERIUM; HETEROZYGOSITY; HUMAN; HUMAN CELL; INFECTION SENSITIVITY; MICROARRAY ANALYSIS; PERIODONTITIS; PHENOTYPE; POLYMERASE CHAIN REACTION; PORPHYROMONAS GINGIVALIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; WILD TYPE;

AMINO ACID SUBSTITUTION; ASPARTIC ACID; CELLS, CULTURED; GENE EXPRESSION PROFILING; GENETIC PREDISPOSITION TO DISEASE; GINGIVA; GLYCINE; HETEROZYGOTE; HUMANS; ISOLEUCINE; POLYMORPHISM, GENETIC; PORPHYROMONAS GINGIVALIS; THREONINE; TOLL-LIKE RECEPTOR 4; TOLL-LIKE RECEPTORS;

BACTERIA (MICROORGANISMS); NEGIBACTERIA; PORPHYROMONAS GINGIVALIS;

EID: 33646148510     PISSN: 14664879     EISSN: 14765470     Source Type: Journal    
DOI: 10.1038/sj.gene.6364282     Document Type: Article

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