Synthesis and biochemical evaluation of phosphonoformate oligodeoxyribonucleotides

Journal of the American Chemical Society

Volumn 128, Issue 15, 2006, Pages 5251-5261

  Yamada, Christina M ^a   Dellinger, Douglas J ^a,b   Caruthers, Marvin H ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b AGILENT LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; ESTERS; OLIGOMERS; OXIDATION; POROUS MATERIALS; SYNTHESIS (CHEMICAL);

CHIMERIC OLIGOMERS; FORMIC ACID; PHOSPHONOFORMATE OLIGODEOXYRIBONUCLEOTIDES;

NITROGEN COMPOUNDS;

2' DEOXYNUCLEOSIDE; 3' O PHOSPHINOAMIDITE; 4,5 DICYANOIMIDAZOLE; 9 FLUORENYLMETHYLOXYCARBONYL DERIVATIVE; [BIS(N,N DIISOPROPYLAMINO)PHOSPHINO] BETA (DIPHENYLMETHYLSILYLETHYL)ESTER; ADENINE DERIVATIVE; BIS(N,N DIISOPROPYLAMINO)PHOSPHINE; COMPLEMENTARY RNA; CYTOSINE DERIVATIVE; FORMIC ACID; FORMIC ACID DERIVATIVE; FOSCARNET; FOSCARNET DERIVATIVE; GLASS; GUANINE DERIVATIVE; HYDROQUINONE O,O' DIACETIC ACID; IMIDAZOLE DERIVATIVE; MONOMER; NUCLEASE; OLIGODEOXYRIBONUCLEOTIDE; OLIGOMER; PHOSPHATE; PHOSPHINE DERIVATIVE; PHOSPHONOFORMATE OLIGODEOXYRIBONUCLEOTIDE; RIBONUCLEASE H; SODIUM; TETRAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CIRCULAR DICHROISM; COMPLEX FORMATION; ENZYME ACTIVITY; EVALUATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MELTING POINT; OXIDATION; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; POLYMERIZATION; PROTON NUCLEAR MAGNETIC RESONANCE; PURIFICATION; REACTION ANALYSIS; SOLID PHASE SYNTHESIS; STRUCTURE ANALYSIS;

BIOPHYSICS; FOSCARNET; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; OLIGODEOXYRIBONUCLEOTIDES;

EID: 33646130868     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja060112b     Document Type: Article

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