The ratio of P40 monomer to dimer is an important determinant of IL-12 bioactivity

Journal of Theoretical Biology

Volumn 240, Issue 2, 2006, Pages 323-335

  Klinke II, David J ^a  

^a West Virginia University   (United States)

Author keywords

Cytokine receptors; Cytokines; Dendritic cells; Human; Mathematical model

Indexed keywords

DIMER; GAMMA INTERFERON; INTERFERON; INTERLEUKIN 12; INTERLEUKIN 12 RECEPTOR; INTERLEUKIN 12P40; INTERLEUKIN 12P70; INTERLEUKIN 4; MONOMER; PROSTAGLANDIN E2; PROTEIN P40; PROTEIN SUBUNIT;

BIOACTIVITY; CONCENTRATION (COMPOSITION); MATHEMATICAL THEORY; MODELING; PHYSIOLOGY;

ARTICLE; CYTOKINE PRODUCTION; DENDRITIC CELL; DRUG ACTIVITY; HUMAN; HUMAN CELL; MATHEMATICAL MODEL; PRIORITY JOURNAL; SPECIES;

DENDRITIC CELLS; DINOPROSTONE; HUMANS; INTERFERON TYPE II; INTERFERON-GAMMA; INTERLEUKIN-12; INTERLEUKIN-12 SUBUNIT P35; INTERLEUKIN-12 SUBUNIT P40; INTERLEUKIN-4; MODELS, BIOLOGICAL; MODELS, CHEMICAL; RECEPTORS, INTERLEUKIN-12;

EID: 33646107620     PISSN: 00225193     EISSN: 10958541     Source Type: Journal    
DOI: 10.1016/j.jtbi.2005.09.022     Document Type: Article

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