메뉴 건너뛰기




Volumn 11, Issue 2, 2006, Pages 100-109

A Model for Efficient Assay Development and Screening at a Small Research Site

Author keywords

assay development; novel technology; team building; technology strategy

Indexed keywords

AUTOMATION; DRUG PRODUCTS; MATHEMATICAL MODELS; OPTIMIZATION;

EID: 33646011956     PISSN: 22110682     EISSN: 15402452     Source Type: Journal    
DOI: 10.1016/j.jala.2006.02.001     Document Type: Article
Times cited : (4)

References (16)
  • 2
    • 0035672274 scopus 로고    scopus 로고
    • High throughput fluorescence assays for the measurement of mitochondrial activity in intact human neuroblastoma cells
    • Woollacott A. J. Simpson P. B. High throughput fluorescence assays for the measurement of mitochondrial activity in intact human neuroblastoma cells. J. Biomol. Screen. 2001, 6, 407–14.
    • (2001) J. Biomol. Screen. , vol.6 , pp. 407-414
    • Woollacott, A.J.1    Simpson, P.B.2
  • 4
    • 0035869428 scopus 로고    scopus 로고
    • Miniaturization of a hepatitis C virus RNA polymerase assay using a −102 degrees C cooled CCD camera-based imaging system
    • Zheng W. Carroll S. S. Inglese J. Graves R. Howells L. Strulovici B. Miniaturization of a hepatitis C virus RNA polymerase assay using a −102 degrees C cooled CCD camera-based imaging system Anal. Biochem. 2001, 290, 214–20.
    • (2001) Anal. Biochem. , vol.290 , pp. 214-220
    • Zheng, W.1    Carroll, S.S.2    Inglese, J.3    Graves, R.4    Howells, L.5    Strulovici, B.6
  • 6
    • 0035892638 scopus 로고    scopus 로고
    • Retinoic acid-evoked differentiation of neuroblastoma cells predominates over growth factor stimulation: An automated image capture and quantitation approach to neuritogenesis
    • Simpson P. B. Bacha J. I. Palfreyman E. L. Woollacott A. J. McKernan R. M. Kerby J. Retinoic acid-evoked differentiation of neuroblastoma cells predominates over growth factor stimulation: An automated image capture and quantitation approach to neuritogenesis. Anal. Biochem. 2001, 298, 163–9.
    • (2001) Anal. Biochem. , vol.298 , pp. 163-169
    • Simpson, P.B.1    Bacha, J.I.2    Palfreyman, E.L.3    Woollacott, A.J.4    McKernan, R.M.5    Kerby, J.6
  • 9
    • 32944465278 scopus 로고    scopus 로고
    • High content kinetic assays of neuronal signalling implemented on BD Pathway HT
    • Chan G. K. Y. Richards G. R. Peters M. Simpson P. B. High content kinetic assays of neuronal signalling implemented on BD Pathway HT. Assay Drug Dev. Technol 2005, 3, 623–36.
    • (2005) Assay Drug Dev. Technol , vol.3 , pp. 623-636
    • Chan, G.K.Y.1    Richards, G.R.2    Peters, M.3    Simpson, P.B.4
  • 10
    • 39049179232 scopus 로고    scopus 로고
    • Automated cell plating and sample treatments for fixed cells in high content assays
    • In High Content Screening: A powerful approach to systems cell biology and drug discovery; Giuliano K. A. Taylor D. L. Haskin J.; Eds., Totowa NJ: Humana Press, Inc.
    • Richards G. R. Kerby J. E. Chan G. K. Y. Simpson P. B. Automated cell plating and sample treatments for fixed cells in high content assays. Methods Mol. Biol. Vol. 356. In High Content Screening: A powerful approach to systems cell biology and drug discovery; Giuliano K. A. Taylor D. L. Haskin J.; Eds., Totowa NJ: Humana Press, Inc.; 2006;.
    • (2006) Methods Mol. Biol. , vol.356
    • Richards, G.R.1    Kerby, J.E.2    Chan, G.K.Y.3    Simpson, P.B.4
  • 11
    • 0034708421 scopus 로고    scopus 로고
    • Functional characterization of bradykinin analogues on Chinese Hamster Ovary cells expressing recombinant human B1 and B2 bradykinin receptors
    • Simpson P. B. Woollacott A. J. Hill R. G. Seabrook G. R. Functional characterization of bradykinin analogues on Chinese Hamster Ovary cells expressing recombinant human B1 and B2 bradykinin receptors. Eur. J. Pharmacol. 2000, 392, 1–9.
    • (2000) Eur. J. Pharmacol. , vol.392 , pp. 1-9
    • Simpson, P.B.1    Woollacott, A.J.2    Hill, R.G.3    Seabrook, G.R.4
  • 12
    • 6344256342 scopus 로고    scopus 로고
    • Compounds exhibiting selective efficacy for different β subunits of human recombinant GABAA receptors
    • Smith A. J. Oxley B. Malpas S. Pillai G. V. Simpson P. B. Compounds exhibiting selective efficacy for different β subunits of human recombinant GABAA receptors. J. Pharmacol. Exp. Ther. 2004, 311, 611–9.
    • (2004) J. Pharmacol. Exp. Ther. , vol.311 , pp. 611-619
    • Smith, A.J.1    Oxley, B.2    Malpas, S.3    Pillai, G.V.4    Simpson, P.B.5
  • 15
    • 13844286793 scopus 로고    scopus 로고
    • Miniaturization of intracellular calcium functional assays to 1536-well plate format using a fluorometric imaging plate reader
    • Hodder P. Mull R. Cassaday J. Berry K. Strulovici B. Miniaturization of intracellular calcium functional assays to 1536-well plate format using a fluorometric imaging plate reader. J. Biomol. Screen. 2004, 9, 417–26.
    • (2004) J. Biomol. Screen. , vol.9 , pp. 417-426
    • Hodder, P.1    Mull, R.2    Cassaday, J.3    Berry, K.4    Strulovici, B.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.