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Volumn 58, Issue 1, 2006, Pages 13-23

Bortezomib interactions with chemotherapy agents in acute leukemia in vitro

Author keywords

ALL; AML; PS 341; Synergy; VELCADE

Indexed keywords

2 AMINO 6 BROMO 4 (1 CYANO 2 ETHOXY 2 OXOETHYL) 4H CHROMENE 3 CARBOXYLIC ACID ETHYL ESTER; ASPARAGINASE; BORTEZOMIB; CYTARABINE; DEXAMETHASONE; DOXORUBICIN; FLAVOPIRIDOL; GELDANAMYCIN; GEMCITABINE; HISTONE DEACETYLASE INHIBITOR; MELPHALAN; PROTEASOME INHIBITOR; TETRAZOLIUM; TRICHOSTATIN A; VINCRISTINE; VORINOSTAT;

EID: 33646003521     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00280-005-0135-z     Document Type: Article
Times cited : (113)

References (57)
  • 1
    • 0037768158 scopus 로고    scopus 로고
    • Bethesda, MD: National Cancer Institute
    • SEER Cancer Statistic Review, 1973-1999 Bethesda, MD: National Cancer Institute, 2000;467-482
    • (2000) SEER Cancer Statistic Review, 1973-1999 , pp. 467-482
  • 2
    • 0028935165 scopus 로고
    • Ubiquitin, proteasomes, and the regulation of intracellular protein degradation
    • Hochstrasser M (1995) Ubiquitin, proteasomes, and the regulation of intracellular protein degradation. Curr Opin Cell Biol 7:215-223
    • (1995) Curr Opin Cell Biol , vol.7 , pp. 215-223
    • Hochstrasser, M.1
  • 3
    • 0031973765 scopus 로고    scopus 로고
    • The ubiquitin-proteasome pathway in cancer
    • Spataro V, Norbury C, Harris AL (1998) The ubiquitin-proteasome pathway in cancer. Br J Cancer 77:448-455
    • (1998) Br J Cancer , vol.77 , pp. 448-455
    • Spataro, V.1    Norbury, C.2    Harris, A.L.3
  • 4
    • 0028018268 scopus 로고
    • The ubiquitin-proteasome proteolytic pathway
    • Ciechanover A (1994) The ubiquitin-proteasome proteolytic pathway. Cell 79:13-21
    • (1994) Cell , vol.79 , pp. 13-21
    • Ciechanover, A.1
  • 5
    • 0036546501 scopus 로고    scopus 로고
    • NF-kappaB in cancer: From innocent bystander to major culprit
    • Karin M, Cao Y, Greten FR et al (2002) NF-kappaB in cancer: from innocent bystander to major culprit. Nat Rev Cancer 2:301-310
    • (2002) Nat Rev Cancer , vol.2 , pp. 301-310
    • Karin, M.1    Cao, Y.2    Greten, F.R.3
  • 6
    • 18544367201 scopus 로고    scopus 로고
    • NF-kappa B as a therapeutic target in multiple myeloma
    • Hideshima T, Chauhan D, Richardson P et al (2002) NF-kappa B as a therapeutic target in multiple myeloma. J Biol Chem 277:16639-16647
    • (2002) J Biol Chem , vol.277 , pp. 16639-16647
    • Hideshima, T.1    Chauhan, D.2    Richardson, P.3
  • 7
    • 0030016329 scopus 로고    scopus 로고
    • Apoptosis induction resulting from proteasome inhibition
    • Shinohara K, Tomioka M, Nakano H et al (1996) Apoptosis induction resulting from proteasome inhibition. Biochem J 317(Pt 2):385-388
    • (1996) Biochem J , vol.317 , Issue.2 PART , pp. 385-388
    • Shinohara, K.1    Tomioka, M.2    Nakano, H.3
  • 8
    • 0031034160 scopus 로고    scopus 로고
    • Activation of the cell death program by inhibition of proteasome function
    • USA
    • Drexler HC (1997) Activation of the cell death program by inhibition of proteasome function. Proc Natl Acad.Sci USA 94:855-860
    • (1997) Proc Natl AcadSci , vol.94 , pp. 855-860
    • Drexler, H.C.1
  • 9
    • 0033152760 scopus 로고    scopus 로고
    • Proteasome inhibitors: A novel class of potent and effective antitumor agents
    • Adams J, Palombella VJ, Sausville EA et al (1999) Proteasome inhibitors: a novel class of potent and effective antitumor agents. Cancer Res 59:2615-2622
    • (1999) Cancer Res , vol.59 , pp. 2615-2622
    • Adams, J.1    Palombella, V.J.2    Sausville, E.A.3
  • 10
    • 2942692143 scopus 로고    scopus 로고
    • Phase I trial of the proteasome inhibitor bortezomib in patients with advanced solid tumors with observations in androgen-independent prostate cancer
    • Papandreou CN, Daliani DD, Nix D et al (2004) Phase I trial of the proteasome inhibitor bortezomib in patients with advanced solid tumors with observations in androgen-independent prostate cancer. J Clin Oncol 22:2108-2121
    • (2004) J Clin Oncol , vol.22 , pp. 2108-2121
    • Papandreou, C.N.1    Daliani, D.D.2    Nix, D.3
  • 11
    • 0037111832 scopus 로고    scopus 로고
    • Phase I trial of the proteasome inhibitor PS-341 in patients with refractory hematologic malignancies
    • Orlowski RZ, Stinchcombe TE, Mitchell BS et al (2002) Phase I trial of the proteasome inhibitor PS-341 in patients with refractory hematologic malignancies. J Clin Oncol 20:4420-4427
    • (2002) J Clin Oncol , vol.20 , pp. 4420-4427
    • Orlowski, R.Z.1    Stinchcombe, T.E.2    Mitchell, B.S.3
  • 12
    • 0343091329 scopus 로고    scopus 로고
    • Ubiquitin-proteasome system and increased sensitivity of B-CLL lymphocytes to apoptotic death activation
    • Masdehors P, Merle-Beral H, Magdelenat H et al (2000) Ubiquitin-proteasome system and increased sensitivity of B-CLL lymphocytes to apoptotic death activation. Leuk Lymphoma 38:499-504
    • (2000) Leuk Lymphoma , vol.38 , pp. 499-504
    • Masdehors, P.1    Merle-Beral, H.2    Magdelenat, H.3
  • 13
    • 0035300479 scopus 로고    scopus 로고
    • The proteasome inhibitor PS-341 inhibits growth, induces apoptosis, and overcomes drug resistance in human multiple myeloma cells
    • Hideshima T, Richardson P, Chauhan D et al (2001) The proteasome inhibitor PS-341 inhibits growth, induces apoptosis, and overcomes drug resistance in human multiple myeloma cells. Cancer Res 61:3071-3076
    • (2001) Cancer Res , vol.61 , pp. 3071-3076
    • Hideshima, T.1    Richardson, P.2    Chauhan, D.3
  • 14
    • 0035000515 scopus 로고    scopus 로고
    • The apoptogenic response of human myeloid leukaemia cell lines and of normal and malignant haematopoietic progenitor cells to the proteasome inhibitor PSI
    • Soligo D, Servida F, Delia D et al (2001) The apoptogenic response of human myeloid leukaemia cell lines and of normal and malignant haematopoietic progenitor cells to the proteasome inhibitor PSI. Br J Haematol 113:126-135
    • (2001) Br J Haematol , vol.113 , pp. 126-135
    • Soligo, D.1    Servida, F.2    Delia, D.3
  • 15
    • 0037443551 scopus 로고    scopus 로고
    • The proteasome inhibitor PS-341 potentiates sensitivity of multiple myeloma cells to conventional chemotherapeutic agents: Therapeutic applications
    • Mitsiades N, Mitsiades CS, Richardson PG et al (2002) The proteasome inhibitor PS-341 potentiates sensitivity of multiple myeloma cells to conventional chemotherapeutic agents: therapeutic applications. Blood 101:2377-2380
    • (2002) Blood , vol.101 , pp. 2377-2380
    • Mitsiades, N.1    Mitsiades, C.S.2    Richardson, P.G.3
  • 16
    • 0034237661 scopus 로고    scopus 로고
    • Apoptosis and radiosensitization of Hodgkin cells by proteasome inhibition
    • Pajonk F, Pajonk K, McBride WH (2000) Apoptosis and radiosensitization of Hodgkin cells by proteasome inhibition. Int J Radiat Oncol Biol Phys 47:1025-1032
    • (2000) Int J Radiat Oncol Biol Phys , vol.47 , pp. 1025-1032
    • Pajonk, F.1    Pajonk, K.2    McBride, W.H.3
  • 17
    • 0242468166 scopus 로고    scopus 로고
    • Proteasome inhibitors potentiate leukemic cell apoptosis induced by the cyclin-dependent kinase inhibitor flavopiridol through a SAPK/JNK-and NF-kappaB-dependent process
    • Dai Y, Rahmani M, Grant S (2003) Proteasome inhibitors potentiate leukemic cell apoptosis induced by the cyclin-dependent kinase inhibitor flavopiridol through a SAPK/JNK-and NF-kappaB-dependent process. Oncogene 22:7108-7122
    • (2003) Oncogene , vol.22 , pp. 7108-7122
    • Dai, Y.1    Rahmani, M.2    Grant, S.3
  • 18
    • 3142554015 scopus 로고    scopus 로고
    • Bortezomib and flavopiridol interact synergistically to induce apoptosis in chronic myeloid leukemia cells resistant to imatinib mesylate through both Bcr/Abl-dependent and -independent mechanisms
    • Dai Y, Rahmani M, Pei XY et al (2004) Bortezomib and flavopiridol interact synergistically to induce apoptosis in chronic myeloid leukemia cells resistant to imatinib mesylate through both Bcr/Abl-dependent and -independent mechanisms. Blood 104:509-518
    • (2004) Blood , vol.104 , pp. 509-518
    • Dai, Y.1    Rahmani, M.2    Pei, X.Y.3
  • 19
    • 9144220841 scopus 로고    scopus 로고
    • Transcriptional signature of histone deacetylase inhibition in multiple myeloma: Biological and clinical implications
    • USA
    • Mitsiades CS, Mitsiades NS, McMullan CJ et al (2004) Transcriptional signature of histone deacetylase inhibition in multiple myeloma: biological and clinical implications. Proc Natl Acad Sci USA 101:540-545
    • (2004) Proc Natl Acad Sci , vol.101 , pp. 540-545
    • Mitsiades, C.S.1    Mitsiades, N.S.2    McMullan, C.J.3
  • 20
    • 2542616162 scopus 로고    scopus 로고
    • Synergistic effect of histone deacetylase inhibitors FK228 and m-carboxycinnamic acid bis-hydroxamide with proteasome inhibitors PSI and PS-341 against gastrointestinal adenocarcinoma cells
    • Adachi M, Zhang Y, Zhao X et al (2004) Synergistic effect of histone deacetylase inhibitors FK228 and m-carboxycinnamic acid bis-hydroxamide with proteasome inhibitors PSI and PS-341 against gastrointestinal adenocarcinoma cells. Clin Cancer Res 10:3853-3862
    • (2004) Clin Cancer Res , vol.10 , pp. 3853-3862
    • Adachi, M.1    Zhang, Y.2    Zhao, X.3
  • 21
    • 0142244338 scopus 로고    scopus 로고
    • The proteasome inhibitor bortezomib promotes mitochondrial injury and apoptosis induced by the small molecule Bcl-2 inhibitor HA14-1 in multiple myeloma cells
    • Pei XY, Dai Y, Grant S (2003) The proteasome inhibitor bortezomib promotes mitochondrial injury and apoptosis induced by the small molecule Bcl-2 inhibitor HA14-1 in multiple myeloma cells. Leukemia 17:2036-2045
    • (2003) Leukemia , vol.17 , pp. 2036-2045
    • Pei, X.Y.1    Dai, Y.2    Grant, S.3
  • 22
    • 0032508414 scopus 로고    scopus 로고
    • NF-kappaB antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation
    • Wang CY, Mayo MW, Korneluk RG et al (1998) NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation. Science 281:1680-1683
    • (1998) Science , vol.281 , pp. 1680-1683
    • Wang, C.Y.1    Mayo, M.W.2    Korneluk, R.G.3
  • 23
    • 0032905030 scopus 로고    scopus 로고
    • Control of inducible chemoresistance: Enhanced anti-tumor therapy through increased apoptosis by inhibition of NF-kappaB
    • Wang CY, Cusack JC Jr, Liu R et al (1999) Control of inducible chemoresistance: enhanced anti-tumor therapy through increased apoptosis by inhibition of NF-kappaB. Nature Medicine 5:412-417
    • (1999) Nature Medicine , vol.5 , pp. 412-417
    • Wang, C.Y.1    Cusack Jr., J.C.2    Liu, R.3
  • 24
    • 0034744586 scopus 로고    scopus 로고
    • Characterization of NF-kappaB expression in Hodgkin's disease: Inhibition of constitutively expressed NF-kappaB results in spontaneous caspase-independent apoptosis in Hodgkin and Reed-Sternberg cells
    • Izban KF, Ergin M, Huang Q et al (2001) Characterization of NF-kappaB expression in Hodgkin's disease: inhibition of constitutively expressed NF-kappaB results in spontaneous caspase-independent apoptosis in Hodgkin and Reed-Sternberg cells. Mod.Pathol 14:297-310
    • (2001) Mod Pathol , vol.14 , pp. 297-310
    • Izban, K.F.1    Ergin, M.2    Huang, Q.3
  • 25
    • 2942706263 scopus 로고    scopus 로고
    • Proteasome inhibition in hematologic malignancies
    • Richardson PG, Hideshima T, Mitsiades C et al (2004) Proteasome inhibition in hematologic malignancies. Ann Med 36:304-314
    • (2004) Ann Med , vol.36 , pp. 304-314
    • Richardson, P.G.1    Hideshima, T.2    Mitsiades, C.3
  • 26
    • 20444433230 scopus 로고    scopus 로고
    • Bortezomib or high-dose dexamethasone for relapsed multiple myeloma
    • Richardson PG, Sonneveld P, Schuster MW et al (2005) Bortezomib or high-dose dexamethasone for relapsed multiple myeloma. N Engl J Med 352:2487-2498
    • (2005) N Engl J Med , vol.352 , pp. 2487-2498
    • Richardson, P.G.1    Sonneveld, P.2    Schuster, M.W.3
  • 27
    • 20044376092 scopus 로고    scopus 로고
    • Phase II clinical experience with the novel proteasome inhibitor bortezomib in patients with indolent non-Hodgkin's lymphoma and mantle cell lymphoma
    • O'Connor OA, Wright J, Moskowitz C et al (2005) Phase II clinical experience with the novel proteasome inhibitor bortezomib in patients with indolent non-Hodgkin's lymphoma and mantle cell lymphoma. J Clin Oncol 23:676-684
    • (2005) J Clin Oncol , vol.23 , pp. 676-684
    • O'Connor, O.A.1    Wright, J.2    Moskowitz, C.3
  • 28
    • 20044396543 scopus 로고    scopus 로고
    • Phase II study of proteasome inhibitor bortezomib in relapsed or refractory B-cell non-Hodgkin's lymphoma
    • Goy A, Younes A, McLaughlin P et al (2005) Phase II study of proteasome inhibitor bortezomib in relapsed or refractory B-cell non-Hodgkin's lymphoma. J Clin Oncol 23:667-675
    • (2005) J Clin Oncol , vol.23 , pp. 667-675
    • Goy, A.1    Younes, A.2    McLaughlin, P.3
  • 29
    • 0033920566 scopus 로고    scopus 로고
    • Protease inhibitor-induced apoptosis: Accumulation of wt p53, p21WAF1/CIP1, and induction of apoptosis are independent markers of proteasome inhibition
    • An WG, Hwang SG, Trepel JB et al (2000) Protease inhibitor-induced apoptosis: accumulation of wt p53, p21WAF1/CIP1, and induction of apoptosis are independent markers of proteasome inhibition. Leukemia 14:1276-1283
    • (2000) Leukemia , vol.14 , pp. 1276-1283
    • An, W.G.1    Hwang, S.G.2    Trepel, J.B.3
  • 30
    • 1842861723 scopus 로고    scopus 로고
    • The hierarchical relationship between MAPK signaling and ROS generation in human leukemia cells undergoing apoptosis in response to the proteasome inhibitor Bortezomib
    • Yu C, Rahmani M, Dent P et al (2004) The hierarchical relationship between MAPK signaling and ROS generation in human leukemia cells undergoing apoptosis in response to the proteasome inhibitor Bortezomib. Exp Cell Res 295:555-566
    • (2004) Exp Cell Res , vol.295 , pp. 555-566
    • Yu, C.1    Rahmani, M.2    Dent, P.3
  • 31
    • 0036172154 scopus 로고    scopus 로고
    • Proteasome inhibitor PS-341, a potential therapeutic agent for adult T- cell leukemia
    • Tan C, Waldmann TA (2002) Proteasome inhibitor PS-341, a potential therapeutic agent for adult T- cell leukemia. Cancer Res 62:1083-1086
    • (2002) Cancer Res , vol.62 , pp. 1083-1086
    • Tan, C.1    Waldmann, T.A.2
  • 32
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
    • Mosmann T (1983) Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 65:55-63
    • (1983) J Immunol Methods , vol.65 , pp. 55-63
    • Mosmann, T.1
  • 33
    • 0023130372 scopus 로고
    • Evaluation of a tetrazolium-based semiautomated colorimetric assay: Assessment of chemosensitivity testing
    • Carmichael J, DeGraff WG, Gazdar AF et al (1987) Evaluation of a tetrazolium-based semiautomated colorimetric assay: assessment of chemosensitivity testing. Cancer Res 47:936-942
    • (1987) Cancer Res , vol.47 , pp. 936-942
    • Carmichael, J.1    Degraff, W.G.2    Gazdar, A.F.3
  • 34
    • 0025113618 scopus 로고
    • Application of a new approach for the quantitation of drug synergism to the combination of cis-diamminedichloroplatinum and 1-beta-D-arabinofuranosylcytosine
    • Greco WR, Park HS, Rustum YM (1990) Application of a new approach for the quantitation of drug synergism to the combination of cis-diamminedichloroplatinum and 1-beta-D-arabinofuranosylcytosine. Cancer Res 50:5318-5327
    • (1990) Cancer Res , vol.50 , pp. 5318-5327
    • Greco, W.R.1    Park, H.S.2    Rustum, Y.M.3
  • 36
    • 0021118703 scopus 로고
    • Quantitative analysis of dose effect relationship: The combined effects of multiple drugs or enzyme inhibitors
    • Chou T, Talalay C (1984) Quantitative analysis of dose effect relationship: the combined effects of multiple drugs or enzyme inhibitors. Adv Enzyme Regul 22:27-55
    • (1984) Adv Enzyme Regul , vol.22 , pp. 27-55
    • Chou, T.1    Talalay, C.2
  • 37
    • 0037973279 scopus 로고    scopus 로고
    • A phase 2 study of bortezomib in relapsed, refractory myeloma
    • Richardson PG, Barlogie B, Berenson J et al (2003) A phase 2 study of bortezomib in relapsed, refractory myeloma. N Engl J Med 348:2609-2617
    • (2003) N Engl J Med , vol.348 , pp. 2609-2617
    • Richardson, P.G.1    Barlogie, B.2    Berenson, J.3
  • 39
    • 0038189917 scopus 로고    scopus 로고
    • Rationale for the treatment of solid tumors with the proteasome inhibitor bortezomib
    • Cusack JC (2003) Rationale for the treatment of solid tumors with the proteasome inhibitor bortezomib. Cancer Treat Rev 29(Suppl 1):21-31
    • (2003) Cancer Treat Rev , vol.29 , Issue.1 SUPPL. , pp. 21-31
    • Cusack, J.C.1
  • 40
    • 0141761420 scopus 로고    scopus 로고
    • The proteasome inhibitor PS-341 inhibits growth and induces apoptosis in B positive cell lines sensitive and resistant to imatinib mesylate
    • Gatto S, Scappini B, Pham L et al (2003) The proteasome inhibitor PS-341 inhibits growth and induces apoptosis in B positive cell lines sensitive and resistant to imatinib mesylate. Haematologica 88:853-863
    • (2003) Haematologica , vol.88 , pp. 853-863
    • Gatto, S.1    Scappini, B.2    Pham, L.3
  • 41
    • 0242493856 scopus 로고    scopus 로고
    • The proteasome inhibitor bortezomib interacts synergistically with histone deacetylase inhibitors to induce apoptosis in Bcr/Abl+ cells sensitive and resistant to ST1571
    • Yu C, Rahmani M, Conrad D et al (2003) The proteasome inhibitor bortezomib interacts synergistically with histone deacetylase inhibitors to induce apoptosis in Bcr/Abl+ cells sensitive and resistant to ST1571. Blood 102:3765-3774
    • (2003) Blood , vol.102 , pp. 3765-3774
    • Yu, C.1    Rahmani, M.2    Conrad, D.3
  • 42
    • 6344265692 scopus 로고    scopus 로고
    • Antitumor effects of bortezomib (PS-341) on primary effusion lymphomas
    • An J, Sun Y, Fisher M et al (2004) Antitumor effects of bortezomib (PS-341) on primary effusion lymphomas. Leukemia 18:1699-1704
    • (2004) Leukemia , vol.18 , pp. 1699-1704
    • An, J.1    Sun, Y.2    Fisher, M.3
  • 43
    • 2442549643 scopus 로고    scopus 로고
    • Induction of cell cycle arrest and apoptosis by the proteasome inhibitor PS-341 in Hodgkin disease cell lines is independent of inhibitor of nuclear factor-kappaB mutations or activation of the CD30, CD40, and RANK receptors
    • Zheng B, Georgakis GV, Li Y et al (2004) Induction of cell cycle arrest and apoptosis by the proteasome inhibitor PS-341 in Hodgkin disease cell lines is independent of inhibitor of nuclear factor-kappaB mutations or activation of the CD30, CD40, and RANK receptors. Clin Cancer Res 10:3207-3215
    • (2004) Clin Cancer Res , vol.10 , pp. 3207-3215
    • Zheng, B.1    Georgakis, G.V.2    Li, Y.3
  • 44
    • 3342977158 scopus 로고    scopus 로고
    • 2-Methoxyestardiol and bortezomib/proteasome-inhibitor overcome dexamethasone-resistance in multiple myeloma cells by modulating Heat Shock Protein-27
    • Chauhan D, Li G, Auclair D et al (2004) 2-Methoxyestardiol and bortezomib/proteasome-inhibitor overcome dexamethasone-resistance in multiple myeloma cells by modulating Heat Shock Protein-27. Apoptosis 9:149-155
    • (2004) Apoptosis , vol.9 , pp. 149-155
    • Chauhan, D.1    Li, G.2    Auclair, D.3
  • 45
    • 2542420166 scopus 로고    scopus 로고
    • Morphoproteomics and bortezomib/dexamethasone-induced response in relapsed acute lymphoblastic leukemia
    • Brown RE, Bostrom B, Zhang PL (2004) Morphoproteomics and bortezomib/dexamethasone-induced response in relapsed acute lymphoblastic leukemia. Ann.Clin Lab Sci 34:203-205
    • (2004) Ann Clin Lab Sci , vol.34 , pp. 203-205
    • Brown, R.E.1    Bostrom, B.2    Zhang, P.L.3
  • 47
    • 0032527904 scopus 로고    scopus 로고
    • Super in vitro synergy between inhibitors of dihydrofolate reductase and inhibitors of other folate-requiring enzymes: The critical role of polyglutamylation
    • Faessel HM, Slocum HK, Jackson RC et al (1998) Super in vitro synergy between inhibitors of dihydrofolate reductase and inhibitors of other folate-requiring enzymes: the critical role of polyglutamylation. Cancer Res 58:3036-3050
    • (1998) Cancer Res , vol.58 , pp. 3036-3050
    • Faessel, H.M.1    Slocum, H.K.2    Jackson, R.C.3
  • 48
    • 0002658308 scopus 로고
    • Quantitation of synergism and antagonism of two or more drugs by computerized analysis
    • Chou JH (1991) Quantitation of synergism and antagonism of two or more drugs by computerized analysis. Synergism and antagonism in chemotherapy pp 223-241
    • (1991) Synergism and Antagonism in Chemotherapy , pp. 223-241
    • Chou, J.H.1
  • 49
    • 2542523228 scopus 로고    scopus 로고
    • Synergistic induction of oxidative injury and apoptosis in human multiple myeloma cells by the proteasome inhibitor bortezmib and histone deacetylase inhibitors
    • Pei XY, Dai Y, Grant S (2004) Synergistic induction of oxidative injury and apoptosis in human multiple myeloma cells by the proteasome inhibitor bortezmib and histone deacetylase inhibitors. Clin Cancer Res 10:3839-3852
    • (2004) Clin Cancer Res , vol.10 , pp. 3839-3852
    • Pei, X.Y.1    Dai, Y.2    Grant, S.3
  • 50
    • 0029036955 scopus 로고
    • The search for synergy: A critical review from a response surface perspective
    • Greco WR, Bravo G, Parsons JC (1995) The search for synergy: a critical review from a response surface perspective. Pharmacol Rev 47:331-385
    • (1995) Pharmacol Rev , vol.47 , pp. 331-385
    • Greco, W.R.1    Bravo, G.2    Parsons, J.C.3
  • 51
    • 0024847290 scopus 로고
    • What is synergy?
    • Berenbaum MC (1989) What is synergy? Pharmacol Rev 41:93-141
    • (1989) Pharmacol Rev , vol.41 , pp. 93-141
    • Berenbaum, M.C.1
  • 52
    • 0035148677 scopus 로고    scopus 로고
    • In vitro preclinical models for a rational design of chemotherapy combinations in human tumors
    • Zoli W, Ricotti L, Tesei A et al (2001) In vitro preclinical models for a rational design of chemotherapy combinations in human tumors. Crit Rev Oncol Hematol 37:69-82
    • (2001) Crit Rev Oncol Hematol , vol.37 , pp. 69-82
    • Zoli, W.1    Ricotti, L.2    Tesei, A.3
  • 53
    • 0034527287 scopus 로고    scopus 로고
    • Rational approach to the clinical protocol design for drug combinations: A review
    • Chang TT, Chou TC (2000) Rational approach to the clinical protocol design for drug combinations: a review. Acta Paediatr Taiwan 41:294-302
    • (2000) Acta Paediatr Taiwan , vol.41 , pp. 294-302
    • Chang, T.T.1    Chou, T.C.2
  • 54
    • 2342625412 scopus 로고    scopus 로고
    • Ubiquitination and proteasomal degradation of nucleophosmin-anaplastic lymphoma kinase induced by 17-allylamino-demethoxygeldanamycin: Role of the co-chaperone carboxyl heat shock protein 70-interacting protein
    • Bonvini P, Dalla RH, Vignes N et al (2004) Ubiquitination and proteasomal degradation of nucleophosmin-anaplastic lymphoma kinase induced by 17-allylamino-demethoxygeldanamycin: role of the co-chaperone carboxyl heat shock protein 70-interacting protein. Cancer Res 64:3256-3264
    • (2004) Cancer Res , vol.64 , pp. 3256-3264
    • Bonvini, P.1    Dalla, R.H.2    Vignes, N.3
  • 55
    • 2942706263 scopus 로고    scopus 로고
    • Proteasome inhibition in hematologic malignancies
    • Richardson PG, Hideshima T, Mitsiades C et al (2004) Proteasome inhibition in hematologic malignancies. Ann Med 36:304-314
    • (2004) Ann Med , vol.36 , pp. 304-314
    • Richardson, P.G.1    Hideshima, T.2    Mitsiades, C.3
  • 56
    • 16544389047 scopus 로고    scopus 로고
    • Phase I study of the proteasome inhibitor bortezomib in pediatric patients with refractory solid tumors: A Children's Oncology Group study (ADVL0015)
    • Blaney SM, Bernstein M, Neville K et al (2004) Phase I study of the proteasome inhibitor bortezomib in pediatric patients with refractory solid tumors: a Children's Oncology Group study (ADVL0015). J Clin Oncol 22:4752-4757
    • (2004) J Clin Oncol , vol.22 , pp. 4752-4757
    • Blaney, S.M.1    Bernstein, M.2    Neville, K.3
  • 57
    • 0021118703 scopus 로고
    • Quantitative analysis of dose-effect relationships: The combined effects of multiple drugs or enzyme inhibitors
    • Chou TC, Talalay P (1984) Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors. Adv Enzyme Regul 22:27-55
    • (1984) Adv Enzyme Regul , vol.22 , pp. 27-55
    • Chou, T.C.1    Talalay, P.2


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