Activated microglial supernatant induced motor neuron cytotoxicity is associated with upregulation of the TNFR1 receptor

Neuroscience Research

Volumn 55, Issue 1, 2006, Pages 87-95

  Wen, Weiyan ^a   Sanelli, Teresa ^a   Ge, Weiwen ^a   Strong, Wendy ^a   Strong, Michael J ^a,b  

^a ROBARTS RESEARCH INSTITUTE   (Canada)

^b Department of Clinical Neurological Sciences ^*  (Canada)

Author keywords

ALS; Cytotoxicity; Microglia; Motor neuron; TNF ; TNFR1

Indexed keywords

CELL SURFACE PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPOPOLYSACCHARIDE; TUMOR NECROSIS FACTOR RECEPTOR 1; TUMOR NECROSIS FACTOR RECEPTOR 2;

ANIMAL CELL; ARTICLE; CELL ACTIVATION; CELL DEATH; CONTROLLED STUDY; CYTOTOXICITY; DEGENERATIVE DISEASE; ENZYME ACTIVATION; ENZYME INHIBITION; GENETIC TRANSCRIPTION; HYBRIDOMA CELL CULTURE; MICROGLIA; MOTONEURON; MOTOR NEURON DISEASE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SUPERNATANT; UPREGULATION;

ANIMALS; ANTIBODIES; CELL COUNT; CELL DEATH; CELL LINE; CULTURE MEDIA, CONDITIONED; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; ENZYME INHIBITORS; FLUORESCENT ANTIBODY TECHNIQUE; LIPOPOLYSACCHARIDES; MICE; MICROGLIA; MOTOR NEURONS; NITRIC OXIDE; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE I; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TETRAZOLIUM SALTS; THIAZOLES; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 33645967499     PISSN: 01680102     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neures.2006.02.004     Document Type: Article

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