DNA adduct formation by 7H-dibenzo[c,g]carbazole and its tissue- and organ-specific derivatives in Chinese hamster V79 cell lines stably expressing cytochrome P450 enzymes

Environmental and Molecular Mutagenesis

Volumn 44, Issue 5, 2004, Pages 448-458

  Gábelová, Alena ^a   Binková, Blanka ^b   Valovičová, Zuzana ^a   Šrám, Radim J ^b  

^a CANCER RESEARCH INSTITUTE   (Slovakia)

^b INSTITUTE OF EXPERIMENTAL MEDICINE   (Czech Republic)

Author keywords

Cytochrome P4501A subfamily; Dibenzo c,g carbazoles; DNA adducts; Micronuclei; Single cell gel electrophoresis

Indexed keywords

5,9 DIMETHYLDIBENZO[C,G]CARBAZOLE; 7H DIBENZO[C,G]CARBAZOLE; ACYLTRANSFERASE; AROMATIC COMPOUND; BENZENE DERIVATIVE; CARBAZOLE DERIVATIVE; CELL DNA; CYTOCHROME P450; CYTOCHROME P450 1A; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; DNA FORMAMIDOPYRIMIDINE GLYCOSYLASE; ENDONUCLEASE; N METHYLDIBENZO[C,G]CARBAZOLE; PHOSPHORUS 32; POLYCYCLIC AROMATIC HYDROCARBON; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BIOTRANSFORMATION; CELL LEVEL; CHO CELL; CHROMATOGRAPHY; COMET ASSAY; CONTROLLED STUDY; DNA ADDUCT; DNA DAMAGE; DNA ISOLATION; DNA MODIFICATION; DOSE RESPONSE; ENZYME ACTIVITY; ENZYME ASSAY; EVALUATION; GENOTOXICITY; ISOTOPE LABELING; METABOLIC ACTIVATION; MICRONUCLEUS TEST; NONHUMAN; PROTEIN EXPRESSION; TISSUE SPECIFICITY;

ACETYLTRANSFERASES; ANIMALS; CARBAZOLES; CARCINOGENS; CHO CELLS; COMET ASSAY; CRICETINAE; CYTOCHROME P-450 CYP1A1; CYTOCHROME P-450 CYP1A2; DNA ADDUCTS; DNA DAMAGE; HUMANS; MICRONUCLEI, CHROMOSOME-DEFECTIVE; MUTAGENICITY TESTS; ORGAN SPECIFICITY; TISSUE DISTRIBUTION;

CRICETINAE; CRICETULUS GRISEUS;

EID: 12344321719     PISSN: 08936692     EISSN: None     Source Type: Journal    
DOI: 10.1002/em.20073     Document Type: Article

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