Mitochondrial regulation of hypoxia-induced increase of adrenomedullin mRNA in HL-1 cells

Biochemical and Biophysical Research Communications

Volumn 343, Issue 3, 2006, Pages 885-892

  Pfeil, Uwe ^a   Paddenberg, Renate ^a   Kummer, Wolfgang ^a  

^a JUSTUS LIEBIG UNIVERSITY   (Germany)

Author keywords

Adrenomedullin; Cardiomyocytes; HL 1 cells; Hypoxia; Mitochondria; Oxygen; Reactive oxygen species

Indexed keywords

ADRENOMEDULLIN; FLAVOPROTEIN; MESSENGER RNA; MITOCHONDRIAL COMPLEX I; MITOCHONDRIAL COMPLEX II; OXIDOREDUCTASE; OXYGEN; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; UBIQUINOL CYTOCHROME C REDUCTASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL HYPOXIA; CELL RESPIRATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; HEART MITOCHONDRION; HEART MUSCLE CELL; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OXYGEN CONSUMPTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; RNA INTERFERENCE; SIGNAL TRANSDUCTION; UPREGULATION;

ADRENOMEDULLIN; ANIMALS; CELL HYPOXIA; CELL LINE; ELECTRON TRANSPORT; ELECTRON TRANSPORT CHAIN COMPLEX PROTEINS; ELECTRON TRANSPORT COMPLEX II; FLAVOPROTEINS; GENE EXPRESSION REGULATION; MICE; MITOCHONDRIA, HEART; PEPTIDES; REACTIVE OXYGEN SPECIES; RNA, MESSENGER; UP-REGULATION;

MURINAE;

EID: 33645922751     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2006.03.042     Document Type: Article

References (41)

1. Borger D.R., and Essig D.A. Induction of HSP 32 gene in hypoxic cardiomyocytes is attenuated by treatment with N-acetyl-l-cysteine. Am. J. Physiol. 274 (1998) 965-973
2. Long X., Wu G., Rozanski D.J., Boluyt M.O., Crow M.T., and Lakatta E.G. Hypoxia-induced haem oxygenase-1 gene expression in neonatal rat cardiac myocytes. Heart Lung Circ. 10 (2001) 113-114
3. Kitamura K., Kangawa K., Kawamoto M., Ichiki Y., Nakamura S., Matsuo H., and Eto T. Adrenomedullin: a novel hypotensive peptide isolated from human pheochromocytoma. Biochem. Biophys. Res. Commun. 192 (1993) 553-560
4. Shimosawa T., Matsui H., Xing G., Itakura K., Ando K., and Fujita T. Organ-protective effects of adrenomedullin. Hypertens. Res. 26 Suppl. (2003) 109-112
5. Montuenga L.M., Martínez A., Miller M.J., Unsworth E.J., and Cuttitta F. Expression of adrenomedullin and its receptor during embryogenesis suggests autocrine or paracrine modes of action. Endocrinology 138 (1997) 440-451
6. Cormier-Regard S., Nguyen S.V., and Claycomb W.C. Adrenomedullin gene expression is developmentally regulated and induced by hypoxia in rat ventricular cardiac myocytes. J. Biol. Chem. 273 (1998) 17787-17792
7. Yoshihara F., Horia T., Nishikimi T., Matsuo H., and Kangawa K. Possibile involvement of oxidative stress in hypoxia-induced adrenomedullin secretion in cultured rat cardiomyocytes. Eur. J. Pharmacol. 436 (2002) 1-6
8. Luodonpaa M., Rysa J., Pikkarainen S., Tenhunen O., Tokola H., Puhakka J., Marttila M., Vuolteenaho O., and Ruskoaho H. Mechanisms regulating adrenomedullin gene expression in the left ventricle: role of mechanical load. Regul. Pept. 112 (2003) 153-159
9. Eto T., Kato J., and Kitamura K. Regulation of production and secretion of adrenomedullin in the cardiovascular system. Regul. Pept. 112 (2003) 61-69
10. Nakanishi K., Osada H., Uenoyama M., Kanazawa F., Ohrui N., Masaki Y., Hayashi T., Kanatani Y., Ikeda T., and Kawai T. Expressions of adrenomedullin mRNA and protein in rats with hypobaric hypoxia-induced pulmonary hypertension. Am. J. Physiol. Heart Circ. Physiol. 286 (2004) 2159-2168
11. Bunton D.C., Petrie M.C., Hillier C., Johnston F., and McMurray J.J. The clinical relevance of adrenomedullin: a promising profile?. Pharmacol Ther. 103 (2004) 179-201
12. Tanaka T., Akiyama H., Kanai H., Sato M., Takeda S., Sekiguchi K., Yokoyama T., and Kurabayashi M. Endothelial PAS domain protein 1 (EPAS1) induces adrenomedullin gene expression in cardiac myocytes: role of EPAS1 in an inflammatory response in cardiac myocytres. J. Mol. Cell. Cardiol. 34 (2002) 739-748
13. Schofield C.J., and Ratcliffe P.J. Oxygen sensing by HIF hydroxylases. Nat. Rev. Mol. Cell. Biol. 5 (2004) 343-354
14. Wenger R.H., Stiehl D.P., and Camenisch G. Integration of oxygen signaling at the consensus HRE. Sci. STKE 306 (2005) re12
15. Nakayama K., Frew I.J., Hagensen M., Skals M., Habelhah H., Bhoumik A., Kadoya T., Erdjument-Bromage H., Tempst P., Frappell P.B., Bowtell D.D., and Ronai Z. Siah2 regulates stability of prolyl-hydroxylases, controls HIF1α abundance, and modulates physiological responses to hypoxia. Cell 117 (2004) 941-952
16. Budinger G.R.S., Duranteau J., Chandel N.S., and Schumacker P.T. Hibernation during hypoxia in cardiomyocytes. J. Biol. Chem. 273 (1998) 3320-3326
17. Duranteau J., Chandel N.M.S., Kulisz A., Shao Z., and Schumacker P.T. Intracellular signaling by reactive oxygen species during hypoxia in cardiomyocytes. J. Biol. Chem. 273 (1998) 11619-11624
18. Claycomb W.C., Lanson Jr. N.A., Stallworth B.S., Egeland D.B., Del Carpio J.B., Bahinski A., and Izzo Jr. N.J. HL-1 cells: a cardiac muscle cell line that contracts and retains phenotypic characteristics of the adult cardiomyocyte. Proc. Natl. Acad. Sci. USA 95 (1998) 2979-2984
19. White S.M., Constantin P.E., and Claycomb W.C. Cardiac physiology at the cellular level: use of cultured HL-1 cardiomyocytes for studies of cardiac muscle cell structure and function. Am. J. Physiol. Circ. Physiol. 286 (2004) 823-829
20. Nguyen S.V., and Claycomb W.C. Hypoxia regulates the expression of the adrenomedullin and HIF-1 genes in cultured HL-1 cardiomyocytes. Biochem. Biophys. Res. Commun. 265 (1999) 382-386
21. Schägger H., and Pfeiffer K. Supercomplexes in the respiratory chains of yeast and mammalian mitochondria and bacteria. EMBO J. 19 (2000) 1777-1783
22. Schägger H., de Coo R., Bauer M.F., Hofmann S., Godinot C., and Brandt U. Significance of respirasomes for the assembly/stability of human respiratory chain complex I. J. Biol. Chem. 279 (2004) 36349-36353
23. Lambert A.J., and Brand M.D. Inhibitors of the quinone-binding site allow rapid superoxide production from mitochondrial NADH:ubiquinone oxidoreductase (complex I). J. Biol. Chem. (2004)
24. Matsuno-Yagi A., and Hatefi Y. Ubiquinol-cytochrome c oxidoreductase. The redox reactions of the bis-heme cytochrome b in ubiquinone-sufficient and ubiquinone-deficient systems. J. Biol. Chem. 271 (1996) 6164-6171
25. Chen Y., and Suzuki I. Effects of electron transport inhibitors and uncouplers on the oxidation of ferrous iron and compounds interacting with ferric iron in Acidthiobacillus ferrooxidans. Can. J. Microbiol. 51 (2005) 695-703
26. Doege K., Heine S., Jensen I., and Jelkmann W. Inhibition of mitochondrial respiration elevates oxygen concentration but leaves regulation of hypoxia-inducible factor (HIF) intact. Blood 106 (2005) 2311-2317
27. Wenger R.H. Mitochondria: oxygen sinks rather than sensors?. Med. Hypotheses 66 (2006) 380-383
28. 2 sensing. J. Biol. Chem. 275 (2000) 25130-25138
29. Guzy R., Hoyos B., Robin E., Chen H., Liu L., Mansfield K., Simon M., Hammerling U., and Schumacker P. Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing. Cell Metab. 1 (2005) 401-408
30. Mills E., and Jöbsis F.F. Simultaneous measurement of cytochrome a3 reduction and chemoreceptor afferent activity in the carotid body. Nature 225 (1970) 1147-1149
31. Streller T., Huckstorf C., Pfeiffer C., and Acker H. Unusual cytochrome a592 with low PO2 affinity correlates as putative oxygen sensor with rat carotid body chemoreceptor discharge. FASEB J. 16 (2002) 1277-1279
32. Paddenberg R., Ishaq B., Goldenberg A., Faulhammer P., Braun-Dullaeus R.C., and Kummer W. Essential role of complex II of the respiratory chain in hypoxia-induced ROS generation in the pulmonary vasculature. Am. J. Physiol. Lung Cell. Mol. Physiol. 284 (2003) L710-L719
33. Kulisz A., Chen N., Chandel N.S., Shao Z., and Schumacker P.T. Mitochondrial ROS initiate phosphorylation of p38 MAP kinase during hypoxia in cardiomyocytes. Am. J. Physiol. Lung Cell. Mol. Physiol. 282 (2002) L1324-L1329
34. Hägerhäll C. Succinate: quinone oxidoreductases. Variations on a conserved theme. Biochim. Biophys. Acta. 1320 (1997) 107-141
35. +-channel activity. Proc. Natl. Acad. Sci. USA 101 (2004) 11880-11885
36. Lopez P.S., Castillor C.H., Pastelin G.H., Nernanez M.R., Suarez M.J., Sanchez K.L., and Escalante B.A. Characterization of 3-nitropropionic acid-induced bradycardia in isolated atria. Toxicol. Appl. Pharmacol 148 (1997) 1-6
37. Yang Y., Xu J.X., and Zhou H.M. Inactivation of succinate-ubiquinone reductase in substrate mix. Int. J. Biochem. 30 (1998) 1147-1152
38. 2+ exchanger in hypoxic reoxygenated guinea pig ventricular myocytes. Am. J. Physiol. Heart Circ. Physiol. 286 (2004) H955-H963
39. 2+ channel function during acute hypoxia. Cardiovasc. Res. 67 (2005) 624-635
40. Darmon N., Fernandez Y., Periquet A., and Mitjavila S. Superoxide anion scavenging capacity of a molecule by a polarographic method. Comparison with a colourimetric method. Free Radic. Res. Commun. 17 (1992) 97-107
41. Gerald D., Berra E., Frapart Y., Chan D., Giaccia A., Mansuy D., Pouysségur J., Yaniv M., and Mechta-Grigoriou F. JunD reduces tumor angiogenesis by protecting cells from oxidative stress. Cell 118 (2004) 781-794