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Volumn 48, Issue 6-7, 2006, Pages 541-546

Repeated injection of MK801: An animal model of schizophrenia?

Author keywords

1,2 13C acetate; 1 13C glucose; GABA; Glutamate; Metabolism; MK801; NMDA; NMR spectroscopy

Indexed keywords

ACETIC ACID; CARBON 13; DIZOCILPINE; GLUCOSE; GLUTAMIC ACID; GLUTAMINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; PROTON;

EID: 33645851976     PISSN: 01970186     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuint.2005.11.019     Document Type: Article
Times cited : (58)

References (36)
  • 1
    • 0031466522 scopus 로고    scopus 로고
    • Measurement of glutamate and glutamine in the medial prefrontal cortex of never-treated schizophrenic patients and healthy controls by proton magnetic resonance spectroscopy
    • Bartha R., Williamson P.C., Drost D.J., Malla A., Carr T.J., Cortese L., Canaran G., Rylett R.J., and Neufeld R.W. Measurement of glutamate and glutamine in the medial prefrontal cortex of never-treated schizophrenic patients and healthy controls by proton magnetic resonance spectroscopy. Arch. Gen. Psychiatry 54 (1997) 959-965
    • (1997) Arch. Gen. Psychiatry , vol.54 , pp. 959-965
    • Bartha, R.1    Williamson, P.C.2    Drost, D.J.3    Malla, A.4    Carr, T.J.5    Cortese, L.6    Canaran, G.7    Rylett, R.J.8    Neufeld, R.W.9
  • 2
    • 0028097839 scopus 로고
    • A controlled trial of riluzole in amyotrophic lateral sclerosis. ALS/Riluzole Study Group
    • Bensimon G., Lacomblez L., and Meininger V. A controlled trial of riluzole in amyotrophic lateral sclerosis. ALS/Riluzole Study Group. N. Engl. J. Med. 330 (1994) 585-591
    • (1994) N. Engl. J. Med. , vol.330 , pp. 585-591
    • Bensimon, G.1    Lacomblez, L.2    Meininger, V.3
  • 3
    • 24944532047 scopus 로고    scopus 로고
    • Impaired glutamine metabolism in NMDA receptor hypofunction induced by MK801
    • Brenner E., Kondziella D., Haberg A., and Sonnewald U. Impaired glutamine metabolism in NMDA receptor hypofunction induced by MK801. J. Neurochem. 94 (2005) 1594-1603
    • (2005) J. Neurochem. , vol.94 , pp. 1594-1603
    • Brenner, E.1    Kondziella, D.2    Haberg, A.3    Sonnewald, U.4
  • 5
    • 0032754397 scopus 로고    scopus 로고
    • Neurotransmitter interactions in schizophrenia-therapeutic implications
    • Carlsson A.W.N., and Carlsson M. Neurotransmitter interactions in schizophrenia-therapeutic implications. Biol. Psychiatry 46 (1999) 1388-1395
    • (1999) Biol. Psychiatry , vol.46 , pp. 1388-1395
    • Carlsson, A.W.N.1    Carlsson, M.2
  • 6
  • 8
    • 0030608074 scopus 로고    scopus 로고
    • Olanzapine and fluperlapine mimic clozapine in preventing MK-801 neurotoxicity
    • Farber N.B., Foster J., Duhan N.L., and Olney J.W. Olanzapine and fluperlapine mimic clozapine in preventing MK-801 neurotoxicity. Schizophr. Res. 21 (1996) 33-37
    • (1996) Schizophr. Res. , vol.21 , pp. 33-37
    • Farber, N.B.1    Foster, J.2    Duhan, N.L.3    Olney, J.W.4
  • 9
    • 0031930049 scopus 로고    scopus 로고
    • Serotonergic agents that activate 5HT2A receptors prevent NMDA antagonist neurotoxicity
    • Farber N.B., Hanslick J., Kirby C., McWilliams L., and Olney J.W. Serotonergic agents that activate 5HT2A receptors prevent NMDA antagonist neurotoxicity. Neuropsychopharmacology 18 (1998) 57-62
    • (1998) Neuropsychopharmacology , vol.18 , pp. 57-62
    • Farber, N.B.1    Hanslick, J.2    Kirby, C.3    McWilliams, L.4    Olney, J.W.5
  • 10
    • 85047700000 scopus 로고    scopus 로고
    • Receptor mechanisms and circuitry underlying NMDA antagonist neurotoxicity
    • Farber N.B., Kim S.H., Dikranian K., Jiang X.P., and Heinkel C. Receptor mechanisms and circuitry underlying NMDA antagonist neurotoxicity. Mol. Psychiatry 7 (2002) 32-43
    • (2002) Mol. Psychiatry , vol.7 , pp. 32-43
    • Farber, N.B.1    Kim, S.H.2    Dikranian, K.3    Jiang, X.P.4    Heinkel, C.5
  • 11
    • 0029646097 scopus 로고
    • Age-specific neurotoxicity in the rat associated with NMDA receptor blockade: potential relevance to schizophrenia?
    • Farber N.B., Wozniak D.F., Price M.T., Labruyere J., Huss J., St P.H., and Olney J.W. Age-specific neurotoxicity in the rat associated with NMDA receptor blockade: potential relevance to schizophrenia?. Biol. Psychiatry 38 (1995) 788-796
    • (1995) Biol. Psychiatry , vol.38 , pp. 788-796
    • Farber, N.B.1    Wozniak, D.F.2    Price, M.T.3    Labruyere, J.4    Huss, J.5    St, P.H.6    Olney, J.W.7
  • 12
    • 0042924149 scopus 로고    scopus 로고
    • Regulation of glutamate carboxypeptidase II function in corticolimbic regions of rat brain by phencyclidine, haloperidol, and clozapine
    • Flores C., and Coyle J.T. Regulation of glutamate carboxypeptidase II function in corticolimbic regions of rat brain by phencyclidine, haloperidol, and clozapine. Neuropsychopharmacology 28 (2003) 1227-1234
    • (2003) Neuropsychopharmacology , vol.28 , pp. 1227-1234
    • Flores, C.1    Coyle, J.T.2
  • 13
    • 0034843738 scopus 로고    scopus 로고
    • The emerging role of glutamate in the pathophysiology and treatment of schizophrenia
    • Goff D.C., and Coyle J.T. The emerging role of glutamate in the pathophysiology and treatment of schizophrenia. Am. J. Psychiatry 158 (2001) 1367-1377
    • (2001) Am. J. Psychiatry , vol.158 , pp. 1367-1377
    • Goff, D.C.1    Coyle, J.T.2
  • 14
    • 0042178307 scopus 로고    scopus 로고
    • Multivariate autoregressive modeling of fMRI time series
    • Harrison L., Penny W.D., and Friston K. Multivariate autoregressive modeling of fMRI time series. Neuroimage 19 (2003) 1477-1491
    • (2003) Neuroimage , vol.19 , pp. 1477-1491
    • Harrison, L.1    Penny, W.D.2    Friston, K.3
  • 15
    • 12344327212 scopus 로고    scopus 로고
    • Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergence
    • Harrison P.J., and Weinberger D.R. Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergence. Mol. Psychiatry 10 (2005) 40-68
    • (2005) Mol. Psychiatry , vol.10 , pp. 40-68
    • Harrison, P.J.1    Weinberger, D.R.2
  • 16
    • 0036330668 scopus 로고    scopus 로고
    • Hippocampal neurons in schizophrenia
    • Heckers S., and Konradi C. Hippocampal neurons in schizophrenia. J. Neural. Transm. 109 (2002) 891-905
    • (2002) J. Neural. Transm. , vol.109 , pp. 891-905
    • Heckers, S.1    Konradi, C.2
  • 17
    • 22944435812 scopus 로고    scopus 로고
    • Revising a dogma: ketamine for patients with neurological injury?
    • Himmelseher S., and Durieux M.E. Revising a dogma: ketamine for patients with neurological injury?. Anesth. Analg. 101 (2005) 524-534
    • (2005) Anesth. Analg. , vol.101 , pp. 524-534
    • Himmelseher, S.1    Durieux, M.E.2
  • 18
    • 0025952455 scopus 로고
    • Recent advances in the phencyclidine model of schizophrenia
    • Javitt D.C., and Zukin S.R. Recent advances in the phencyclidine model of schizophrenia. Am. J. Psychiatry 148 (1991) 1301-1308
    • (1991) Am. J. Psychiatry , vol.148 , pp. 1301-1308
    • Javitt, D.C.1    Zukin, S.R.2
  • 19
    • 0032846330 scopus 로고    scopus 로고
    • Excessive cerebrocortical release of acetylcholine induced by NMDA antagonists is reduced by GABAergic and alpha2-adrenergic agonists
    • Kim S.H., Price M.T., Olney J.W., and Farber N.B. Excessive cerebrocortical release of acetylcholine induced by NMDA antagonists is reduced by GABAergic and alpha2-adrenergic agonists. Mol. Psychiatry 4 (1999) 344-352
    • (1999) Mol. Psychiatry , vol.4 , pp. 344-352
    • Kim, S.H.1    Price, M.T.2    Olney, J.W.3    Farber, N.B.4
  • 20
    • 33645855979 scopus 로고    scopus 로고
    • Kondziella, D., Brenner, E., Eyjolfsson, E.M., Markinhuhta, K.R., Carlsson, M., Sonnewald, U., 2005. Glial-neuronal interactions are impaired in the schizophrenia model of repeated MK801 exposure. Neuropsychopharmacology. [Epub ahead of print].
  • 21
  • 22
    • 0141836222 scopus 로고    scopus 로고
    • Excitatory amino acid antagonists for acute stroke
    • Muir K.W., and Lees K.R. Excitatory amino acid antagonists for acute stroke. Cochrane Database Syst. Rev. 3 (2003) CD001244
    • (2003) Cochrane Database Syst. Rev. , vol.3
    • Muir, K.W.1    Lees, K.R.2
  • 23
    • 0029592136 scopus 로고
    • NMDA antagonists as neurotherapeutic drug, psychotogens, neurotoxins, and research tools for studying schizophrenia
    • Olney J.W., and Farber N.B. NMDA antagonists as neurotherapeutic drug, psychotogens, neurotoxins, and research tools for studying schizophrenia. Neuropsychopharmacology 3 (1995) 335-345
    • (1995) Neuropsychopharmacology , vol.3 , pp. 335-345
    • Olney, J.W.1    Farber, N.B.2
  • 24
    • 0028089726 scopus 로고
    • Efficacy of clozapine compared with other antipsychotics in preventing NMDA-antagonist neurotoxicity
    • Olney J.W., and Farber N.B. Efficacy of clozapine compared with other antipsychotics in preventing NMDA-antagonist neurotoxicity. J. Clin. Psychiatry 55 Suppl. B (1994) 43-46
    • (1994) J. Clin. Psychiatry , vol.55 , Issue.SUPPL. B , pp. 43-46
    • Olney, J.W.1    Farber, N.B.2
  • 25
    • 0024338054 scopus 로고
    • Pathological changes induced in cerebrocortical neurons by phencyclidine and related drugs
    • Olney J.W., Labruyere J., and Price M.T. Pathological changes induced in cerebrocortical neurons by phencyclidine and related drugs. Science 244 (1989) 1360-1362
    • (1989) Science , vol.244 , pp. 1360-1362
    • Olney, J.W.1    Labruyere, J.2    Price, M.T.3
  • 26
    • 0034926267 scopus 로고    scopus 로고
    • Sensitization of prepulse inhibition deficits by repeated administration of dizocilpine
    • Schulz B., Fendt M., Pedersen V., and Koch M. Sensitization of prepulse inhibition deficits by repeated administration of dizocilpine. Psychopharmacology (Berl) 156 (2001) 177-181
    • (2001) Psychopharmacology (Berl) , vol.156 , pp. 177-181
    • Schulz, B.1    Fendt, M.2    Pedersen, V.3    Koch, M.4
  • 27
    • 0142031078 scopus 로고    scopus 로고
    • Therapeutic N-methyl-d-aspartate receptor antagonists: Will reality meet expectation?
    • Smith P.F. Therapeutic N-methyl-d-aspartate receptor antagonists: Will reality meet expectation?. Curr. Opin. Investig. Drugs 4 (2003) 826-832
    • (2003) Curr. Opin. Investig. Drugs , vol.4 , pp. 826-832
    • Smith, P.F.1
  • 28
    • 0031239422 scopus 로고    scopus 로고
    • Glutamate transport and metabolism in astrocytes
    • Sonnewald U., Westergaard N., and Schousboe A. Glutamate transport and metabolism in astrocytes. Glia 21 (1997) 56-63
    • (1997) Glia , vol.21 , pp. 56-63
    • Sonnewald, U.1    Westergaard, N.2    Schousboe, A.3
  • 29
    • 0031979134 scopus 로고    scopus 로고
    • Schizophrenia and glutamatergic transmission
    • Tamminga C.A. Schizophrenia and glutamatergic transmission. Crit. Rev. Neurobiol. 12 (1998) 21-36
    • (1998) Crit. Rev. Neurobiol. , vol.12 , pp. 21-36
    • Tamminga, C.A.1
  • 30
    • 27544447486 scopus 로고    scopus 로고
    • Increased prefrontal and hippocampal glutamate concentration in schizophrenia: evidence from a magnetic resonance spectroscopy study
    • Tebartz van E.L., Valerius G., Buchert M., Thiel T., Rusch N., Bubl E., Hennig J., Ebert D., and Olbrich H.M. Increased prefrontal and hippocampal glutamate concentration in schizophrenia: evidence from a magnetic resonance spectroscopy study. Biol. Psychiatry. 58 (2005) 724-730
    • (2005) Biol. Psychiatry. , vol.58 , pp. 724-730
    • Tebartz van, E.L.1    Valerius, G.2    Buchert, M.3    Thiel, T.4    Rusch, N.5    Bubl, E.6    Hennig, J.7    Ebert, D.8    Olbrich, H.M.9
  • 31
    • 7244220611 scopus 로고    scopus 로고
    • Glutamate and glutamine in the anterior cingulate and thalamus of medicated patients with chronic schizophrenia and healthy comparison subjects measured with 4.0-T proton MRS
    • Theberge J., Al-Semaan Y., Williamson P.C., Menon R.S., Neufeld R.W., Rajakumar N., Schaefer B., Densmore M., and Drost D.J. Glutamate and glutamine in the anterior cingulate and thalamus of medicated patients with chronic schizophrenia and healthy comparison subjects measured with 4.0-T proton MRS. Am. J. Psychiatry 160 (2003) 2231-2233
    • (2003) Am. J. Psychiatry , vol.160 , pp. 2231-2233
    • Theberge, J.1    Al-Semaan, Y.2    Williamson, P.C.3    Menon, R.S.4    Neufeld, R.W.5    Rajakumar, N.6    Schaefer, B.7    Densmore, M.8    Drost, D.J.9
  • 33
    • 0036174640 scopus 로고    scopus 로고
    • Glutamatergic mechanisms in schizophrenia
    • Tsai G., and Coyle J.T. Glutamatergic mechanisms in schizophrenia. Annu. Rev. Pharmacol. Toxicol. 42 (2002) 165-179
    • (2002) Annu. Rev. Pharmacol. Toxicol. , vol.42 , pp. 165-179
    • Tsai, G.1    Coyle, J.T.2
  • 34
    • 0032527892 scopus 로고    scopus 로고
    • Preferential utilization of acetate by astrocytes is attributable to transport
    • Waniewski R.A., and Martin D.L. Preferential utilization of acetate by astrocytes is attributable to transport. J. Neurosci. 18 (1998) 5225-5233
    • (1998) J. Neurosci. , vol.18 , pp. 5225-5233
    • Waniewski, R.A.1    Martin, D.L.2
  • 35
  • 36
    • 0032443119 scopus 로고    scopus 로고
    • Disseminated corticolimbic neuronal degeneration induced in rat brain by MK-801: potential relevance to Alzheimer's disease
    • Wozniak D.F., Dikranian K., Ishimaru M.J., Nardi A., Corso T.D., Tenkova T., Olney J.W., and Fix A.S. Disseminated corticolimbic neuronal degeneration induced in rat brain by MK-801: potential relevance to Alzheimer's disease. Neurobiol. Dis. 5 (1998) 305-322
    • (1998) Neurobiol. Dis. , vol.5 , pp. 305-322
    • Wozniak, D.F.1    Dikranian, K.2    Ishimaru, M.J.3    Nardi, A.4    Corso, T.D.5    Tenkova, T.6    Olney, J.W.7    Fix, A.S.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.