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Volumn 8, Issue 3-4, 2005, Pages 245-258

NMDA receptors as targets of heavy metal interaction and toxicity

Author keywords

Lead; Nickel; NMDA receptor structure; NMDA receptors; Zinc

Indexed keywords

LEAD; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NEUROTOXIN; NICKEL; NR2A NMDA RECEPTOR; NR2B NMDA RECEPTOR;

EID: 33645851235     PISSN: 10298428     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF03033978     Document Type: Article
Times cited : (30)

References (74)
  • 1
    • 0025125719 scopus 로고
    • Selective blockade of NMDA-activated channel currents may be implicated in learning deficits caused by lead
    • Alkondon M, AC Costa, V Radhakrishnan, RS Aronstam and EX Albuquerque (1990) Selective blockade of NMDA-activated channel currents may be implicated in learning deficits caused by lead. FEBSLett. 261, 124-130.
    • (1990) FEBSLett , vol.261 , pp. 124-130
    • Alkondon, M.1    Costa, A.C.2    Radhakrishnan, V.3    Aronstam, R.S.4    Albuquerque, E.X.5
  • 2
    • 0023929233 scopus 로고
    • The role of divalent cations in the N-methyl-D-aspartate responses of mouse central neurones in culture
    • Ascher P and L Nowak (1988) The role of divalent cations in the N-methyl-D-aspartate responses of mouse central neurones in culture. J. Physiol. 399, 247-266.
    • (1988) J. Physiol. , vol.399 , pp. 247-266
    • Ascher, P.1    Nowak, L.2
  • 3
    • 0019074711 scopus 로고
    • Selective depression of excitatory amino acid induced depolarizations by magnesium ions in isolated spinal cord preparations
    • Ault B, RH Evans, AA Francis, DJ Oakes and JC Watkins (1980) Selective depression of excitatory amino acid induced depolarizations by magnesium ions in isolated spinal cord preparations. J. Physiol. 307, 413-428.
    • (1980) J. Physiol. , vol.307 , pp. 413-428
    • Ault, B.1    Evans, R.H.2    Francis, A.A.3    Oakes, D.J.4    Watkins, J.C.5
  • 5
    • 0037130451 scopus 로고    scopus 로고
    • Subunit-specific NMDA receptor trafficking to synapses
    • Barria A and R Malinow (2002) Subunit-specific NMDA receptor trafficking to synapses. Neuron 35, 345-353.
    • (2002) Neuron , vol.35 , pp. 345-353
    • Barria, A.1    Malinow, R.2
  • 6
    • 0028819612 scopus 로고
    • Topology profile for a glutamate receptor: Three transmembrane domains and a channel-lining reentrant membrane loop
    • Bennett JA and R Dingledine (1995) Topology profile for a glutamate receptor: Three transmembrane domains and a channel-lining reentrant membrane loop. Neuron 14, 373-384.
    • (1995) Neuron , vol.14 , pp. 373-384
    • Bennett, J.A.1    Dingledine, R.2
  • 7
    • 0028671804 scopus 로고
    • 2+ reduces voltage- and N-methyl-D-aspartate (NMDA)-activated calcium channel currents
    • 2+ reduces voltage- and N-methyl-D-aspartate (NMDA)-activated calcium channel currents. Cell. Mol. Neurobiol. 14, 711-722.
    • (1994) Cell. Mol. Neurobiol. , vol.14 , pp. 711-722
    • Büsselberg, D.1    Michael, D.2    Platt, B.3
  • 8
    • 0026497926 scopus 로고
    • Excitotoxic cell death
    • Choi DW (1992) Excitotoxic cell death. J. Neurobiol. 23, 1261-1276.
    • (1992) J. Neurobiol. , vol.23 , pp. 1261-1276
    • Choi, D.W.1
  • 9
    • 0033136273 scopus 로고    scopus 로고
    • 2+ inhibition of the NMDA receptor
    • 2+ inhibition of the NMDA receptor. Neuron 23, 171-180.
    • (1999) Neuron , vol.23 , pp. 171-180
    • Choi, Y.B.1    Lipton, S.A.2
  • 11
    • 0027461520 scopus 로고
    • Molecular and ionic mimicry of toxic metals
    • Clarkson T (1993) Molecular and ionic mimicry of toxic metals. Annu. Rev. Pharmacol. Toxicol. 32, 545-571
    • (1993) Annu. Rev. Pharmacol. Toxicol. , vol.32 , pp. 545-571
    • Clarkson, T.1
  • 12
    • 0035369112 scopus 로고    scopus 로고
    • NMDA receptor subunits: Diversity, development and disease
    • Cull-Candy S, S Brickley and M Farrant (2001) NMDA receptor subunits: diversity, development and disease. Curr. Opin. Neurobiol. 11, 327-335.
    • (2001) Curr. Opin. Neurobiol. , vol.11 , pp. 327-335
    • Cull-Candy, S.1    Brickley, S.2    Farrant, M.3
  • 13
    • 0027323130 scopus 로고
    • Splice variants of the N-methyl-D-aspartate receptor NR1 identify domains involved in regulation by polyamines and protein kinase C
    • Durand GM, MV Bennett and RS Zukin (1993) Splice variants of the N-methyl-D-aspartate receptor NR1 identify domains involved in regulation by polyamines and protein kinase C. Proc. Natl. Acad. Sci. USA 90, 6731-6735.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 6731-6735
    • Durand, G.M.1    Bennett, M.V.2    Zukin, R.S.3
  • 15
    • 0032523117 scopus 로고    scopus 로고
    • A receptor current by zinc and other divalent cations
    • A receptor current by zinc and other divalent cations. J. Neurosci. 18, 2944-2953.
    • (1998) J. Neurosci. , vol.18 , pp. 2944-2953
    • Fisher, J.L.1    Macdonald, R.L.2
  • 16
    • 0038037859 scopus 로고    scopus 로고
    • Mechanisms of activation, inhibition and specificity: Crystal structures of the NMDA receptor NR1 ligand-binding core
    • Furukawa H and E Gouaux (2003) Mechanisms of activation, inhibition and specificity: Crystal structures of the NMDA receptor NR1 ligand-binding core. Embo J. 22, 2873-2885.
    • (2003) Embo J , vol.22 , pp. 2873-2885
    • Furukawa, H.1    Gouaux, E.2
  • 17
    • 0030803667 scopus 로고    scopus 로고
    • The NR2B-specific interactions of polyamines and protons with the N-methyl-D-aspartate receptor
    • Gallagher MJ, H Huang, ER Grant and DR Lynch (1997) The NR2B-specific interactions of polyamines and protons with the N-methyl-D-aspartate receptor. J. Biol. Chem. 272, 24971-24979.
    • (1997) J. Biol. Chem. , vol.272 , pp. 24971-24979
    • Gallagher, M.J.1    Huang, H.2    Grant, E.R.3    Lynch, D.R.4
  • 18
    • 0030768954 scopus 로고    scopus 로고
    • Mechanisms of modulation by internal protons of cyclic nucleotide-gated channels cloned from sensory receptor cells
    • Gavazzo P, C Picco and A Menini (1997) Mechanisms of modulation by internal protons of cyclic nucleotide-gated channels cloned from sensory receptor cells. Proc. R Soc. Lond. B Biol. Sci. 264, 1157-1165.
    • (1997) Proc. R Soc. Lond. B Biol. Sci. , vol.264 , pp. 1157-1165
    • Gavazzo, P.1    Picco, C.2    Menini, A.3
  • 19
    • 0035828997 scopus 로고    scopus 로고
    • Lead inhibition of NMDA channels in native and recombinant receptors
    • Gavazzo P, A Gazzoli, M Mazzolini and C Marchetti (2001) Lead inhibition of NMDA channels in native and recombinant receptors. Neuroreport 12, 3121-3125.
    • (2001) Neuroreport , vol.12 , pp. 3121-3125
    • Gavazzo, P.1    Gazzoli, A.2    Mazzolini, M.3    Marchetti, C.4
  • 20
    • 0032550160 scopus 로고    scopus 로고
    • Hippocampal NMDA receptor mRNA undergoes subunit specific changes during developmental lead exposure
    • Guilarte TR and JL McGlothan (1998) Hippocampal NMDA receptor mRNA undergoes subunit specific changes during developmental lead exposure. Brain Res. 790, 98-107.
    • (1998) Brain Res , vol.790 , pp. 98-107
    • Guilarte, T.R.1    McGlothan, J.L.2
  • 21
    • 0026619470 scopus 로고
    • 3H]MK-801 binding to the NMDA receptor-gated ionophore: In vitro and in vivo studies
    • 3H]MK-801 binding to the NMDA receptor-gated ionophore: In vitro and in vivo studies. Neurosci. Lett. 148, 27-30.
    • (1992) Neurosci. Lett. , vol.148 , pp. 27-30
    • Guilarte, T.R.1    Miceli, R.C.2
  • 22
    • 0028986970 scopus 로고
    • Biochemical evidence of an interaction of lead at the zinc allosteric sites of the NMDA receptor complex: Effects of neuronal development
    • Guilarte TR, RC Miceli and DA Jett (1995) Biochemical evidence of an interaction of lead at the zinc allosteric sites of the NMDA receptor complex: Effects of neuronal development. Neurotoxicology 16, 63-71.
    • (1995) Neurotoxicology , vol.16 , pp. 63-71
    • Guilarte, T.R.1    Miceli, R.C.2    Jett, D.A.3
  • 23
    • 4644230563 scopus 로고    scopus 로고
    • Amino terminal domain regulation of NMDA receptor function
    • Herin GA and E Aizenman (2004) Amino terminal domain regulation of NMDA receptor function. Eur. J. Pharmacol. 500, 101-111.
    • (2004) Eur. J. Pharmacol. , vol.500 , pp. 101-111
    • Herin, G.A.1    Aizenman, E.2
  • 25
    • 0029893942 scopus 로고    scopus 로고
    • The glycine binding site of the N-methyl-D-aspartate receptor subunit NR1: Identification of novel determinants of co-agonist potentiation in the extracellular M3-M4 loop region
    • Hirai H, J Kirsch, B Laube, H Betz and J Kuhse (1996) The glycine binding site of the N-methyl-D-aspartate receptor subunit NR1: identification of novel determinants of co-agonist potentiation in the extracellular M3-M4 loop region. Proc. Natl. Acad. Sci. USA 93, 6031-6036.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 6031-6036
    • Hirai, H.1    Kirsch, J.2    Laube, B.3    Betz, H.4    Kuhse, J.5
  • 26
    • 0033822534 scopus 로고    scopus 로고
    • Synaptic activity-dependent developmental regulation of NMDA receptor subunit expression in cultured neocortical neurons
    • Hoffmann H, T Gremme, H Hatt and K Gottmann (2000) Synaptic activity-dependent developmental regulation of NMDA receptor subunit expression in cultured neocortical neurons. J. Neurochem. 75, 1590-1599.
    • (2000) J. Neurochem. , vol.75 , pp. 1590-1599
    • Hoffmann, H.1    Gremme, T.2    Hatt, H.3    Gottmann, K.4
  • 28
    • 0027197230 scopus 로고
    • Zinc potentiates agonist-induced currents at certain splice variants of the NMDA receptor
    • Hollmann M, J Boulter, C Maron, L Beasley, J Sullivan, G Pecht and S Heinemann (1993) Zinc potentiates agonist-induced currents at certain splice variants of the NMDA receptor. Neuron 10, 943-954.
    • (1993) Neuron , vol.10 , pp. 943-954
    • Hollmann, M.1    Boulter, J.2    Maron, C.3    Beasley, L.4    Sullivan, J.5    Pecht, G.6    Heinemann, S.7
  • 29
    • 0028596211 scopus 로고
    • N-glycosylation site tagging suggests a three transmembrane domain topology for the glutamate receptor GluR1
    • Hollmann M, C Maron and S Heinemann (1994) N-glycosylation site tagging suggests a three transmembrane domain topology for the glutamate receptor GluR1. Neuron 13, 1331-1343.
    • (1994) Neuron , vol.13 , pp. 1331-1343
    • Hollmann, M.1    Maron, C.2    Heinemann, S.3
  • 30
    • 12844268621 scopus 로고    scopus 로고
    • The function of the amino terminal domain in NMDA receptor modulation
    • Huggins DJ and GH Grant (2005) The function of the amino terminal domain in NMDA receptor modulation. J. Mol. Graph. Model. 23, 381-388.
    • (2005) J. Mol. Graph. Model. , vol.23 , pp. 381-388
    • Huggins, D.J.1    Grant, G.H.2
  • 31
    • 0029052109 scopus 로고
    • Ontogenically related properties of N-methyl-D-aspartate receptors in rat hippocampal neurons and the age-specific sensitivity of developing neurons to lead
    • Ishihara K, M Alkondon, JG Montes and EX Albuquerque (1995) Ontogenically related properties of N-methyl-D-aspartate receptors in rat hippocampal neurons and the age-specific sensitivity of developing neurons to lead. J. Pharmacol. Exp. Ther. 273, 1459-1470.
    • (1995) J. Pharmacol. Exp. Ther. , vol.273 , pp. 1459-1470
    • Ishihara, K.1    Alkondon, M.2    Montes, J.G.3    Albuquerque, E.X.4
  • 32
    • 0035974844 scopus 로고    scopus 로고
    • Rotational movement during cyclic nucleotide-gated channel opening
    • Johnson JP Jr and WN Zagotta (2001) Rotational movement during cyclic nucleotide-gated channel opening. Nature 412, 917-921.
    • (2001) Nature , vol.412 , pp. 917-921
    • Johnson Jr., J.P.1    Zagotta, W.N.2
  • 33
    • 0037088901 scopus 로고    scopus 로고
    • The NMDA receptor M3 segment is a conserved transduction element coupling ligand binding to channel opening
    • Jones KS, HM Van Dongen and AM Van Dongen (2002) The NMDA receptor M3 segment is a conserved transduction element coupling ligand binding to channel opening. J. Neurosci. 22, 2044-2053.
    • (2002) J. Neurosci. , vol.22 , pp. 2044-2053
    • Jones, K.S.1    Van Dongen, H.M.2    Van Dongen, A.M.3
  • 34
    • 0030860597 scopus 로고    scopus 로고
    • Block and modulation of N-methyl-D-aspartate receptors by polyamines and protons: Role of amino acid residues in the transmembrane and pore-forming regions of NR1 and NR2 subunits
    • Kashiwagi K, AJ Pahk, T Masuko, K Igarashi and K Williams (1997) Block and modulation of N-methyl-D-aspartate receptors by polyamines and protons: Role of amino acid residues in the transmembrane and pore-forming regions of NR1 and NR2 subunits. Mol. Pharmacol. 52, 701-713.
    • (1997) Mol. Pharmacol. , vol.52 , pp. 701-713
    • Kashiwagi, K.1    Pahk, A.J.2    Masuko, T.3    Igarashi, K.4    Williams, K.5
  • 35
    • 0036830627 scopus 로고    scopus 로고
    • NMDA receptor pathways as drug targets
    • Kemp JA and RM McKernan (2002) NMDA receptor pathways as drug targets. Nat. Neurosci. 5, 1039-1042.
    • (2002) Nat. Neurosci. , vol.5 , pp. 1039-1042
    • Kemp, J.A.1    McKernan, R.M.2
  • 36
    • 1342308188 scopus 로고    scopus 로고
    • Re-expression of NR2B-containing NMDA receptors in vitro by suppression of neuronal activity
    • Kiyosue K, TY Hiyama, K Nakayama, M Kasai and T Taguchi (2004) Re-expression of NR2B-containing NMDA receptors in vitro by suppression of neuronal activity. Int. J. Dev. Neurosci. 22, 59-65.
    • (2004) Int. J. Dev. Neurosci. , vol.22 , pp. 59-65
    • Kiyosue, K.1    Hiyama, T.Y.2    Nakayama, K.3    Kasai, M.4    Taguchi, T.5
  • 37
    • 0034114521 scopus 로고    scopus 로고
    • Mutation of a glutamate receptor motif reveals its role in gating and delta2 receptor channel properties
    • Kohda K, Y Wang and M Yuzaki (2000) Mutation of a glutamate receptor motif reveals its role in gating and delta2 receptor channel properties. Nat. Neurosci. 3, 315-322.
    • (2000) Nat. Neurosci. , vol.3 , pp. 315-322
    • Kohda, K.1    Wang, Y.2    Yuzaki, M.3
  • 38
    • 0033807575 scopus 로고    scopus 로고
    • Low voltage activated calcium channels: From genes to function
    • Lacinova L, N Klugbauer and F Hofmann (2000) Low voltage activated calcium channels: From genes to function. Gen. Physiol. Biophys. 19, 121-136.
    • (2000) Gen. Physiol. Biophys. , vol.19 , pp. 121-136
    • Lacinova, L.1    Klugbauer, N.2    Hofmann, F.3
  • 39
    • 0037023197 scopus 로고    scopus 로고
    • Different trends in modulation of NMDAR1 and NMDAR2B gene expression in cultured cortical and hippocampal neurons after lead exposure
    • Lau WK, CW Yeung, PW Lui, LH Cheung, NT Poon and KK Yung (2002) Different trends in modulation of NMDAR1 and NMDAR2B gene expression in cultured cortical and hippocampal neurons after lead exposure. Brain Res. 932, 10-24.
    • (2002) Brain Res , vol.932 , pp. 10-24
    • Lau, W.K.1    Yeung, C.W.2    Lui, P.W.3    Cheung, L.H.4    Poon, N.T.5    Yung, K.K.6
  • 40
    • 0034718494 scopus 로고    scopus 로고
    • Molecular determinants of coordinated proton and zinc inhibition of N-methyl-D-aspartate NR1/NR2A receptors
    • Low CM, F Zheng, P Lyuboslavsky and SF Traynelis (2000) Molecular determinants of coordinated proton and zinc inhibition of N-methyl-D-aspartate NR1/NR2A receptors. Proc. Natl. Acad. Sci. USA 97, 11062-11067.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 11062-11067
    • Low, C.M.1    Zheng, F.2    Lyuboslavsky, P.3    Traynelis, S.F.4
  • 43
    • 0038785843 scopus 로고    scopus 로고
    • Molecular targets of lead in brain neurotoxicity
    • Marchetti C (2003) Molecular targets of lead in brain neurotoxicity. Neurotoxicity Res. 5, 221-236.
    • (2003) Neurotoxicity Res , vol.5 , pp. 221-236
    • Marchetti, C.1
  • 44
    • 1642306295 scopus 로고    scopus 로고
    • Subunit-dependent effects of nickel on NMDA receptor channels
    • Marchetti C and P Gavazzo (2003) Subunit-dependent effects of nickel on NMDA receptor channels. Brain Res. Mol. Brain Res. 117, 139-144.
    • (2003) Brain Res. Mol. Brain Res. , vol.117 , pp. 139-144
    • Marchetti, C.1    Gavazzo, P.2
  • 45
    • 0030426640 scopus 로고    scopus 로고
    • Glycine and calcium-dependent effects of lead on N-methyl-D-aspartate receptor function in rat hippocampal neurons
    • Marchioro M, KL Swanson, Y Aracava and EX Albuquerque (1996) Glycine and calcium-dependent effects of lead on N-methyl-D-aspartate receptor function in rat hippocampal neurons. J. Pharmacol. Exp. Ther. 279, 143-153.
    • (1996) J. Pharmacol. Exp. Ther. , vol.279 , pp. 143-153
    • Marchioro, M.1    Swanson, K.L.2    Aracava, Y.3    Albuquerque, E.X.4
  • 46
    • 0033120016 scopus 로고    scopus 로고
    • Structure/function relationships in nickel metallobiochemistry
    • Maroney MJ (1999) Structure/function relationships in nickel metallobiochemistry. Curr. Opin. Chem. Biol. 3, 188-199.
    • (1999) Curr. Opin. Chem. Biol. , vol.3 , pp. 188-199
    • Maroney, M.J.1
  • 47
    • 0033051714 scopus 로고    scopus 로고
    • A regulatory domain (R1-R2) in the amino terminus of the N-methyl-D-aspartate receptor: Effects of spermine, protons, and ifenprodil, and structural similarity to bacterial leucine/isoleucine/ valine binding protein
    • Masuko T, K Kashiwagi, T Kuno, ND Nguyen, AJ Pahk, J Fukuchi, K Igarashi and K Williams (1999) A regulatory domain (R1-R2) in the amino terminus of the N-methyl-D-aspartate receptor: Effects of spermine, protons, and ifenprodil, and structural similarity to bacterial leucine/isoleucine/ valine binding protein. Mol. Pharmacol. 55, 957-969.
    • (1999) Mol. Pharmacol. , vol.55 , pp. 957-969
    • Masuko, T.1    Kashiwagi, K.2    Kuno, T.3    Nguyen, N.D.4    Pahk, A.J.5    Fukuchi, J.6    Igarashi, K.7    Williams, K.8
  • 48
    • 2342462388 scopus 로고    scopus 로고
    • Structure and function of glutamate receptor ion channels
    • Mayer ML and N Armstrong (2004) Structure and function of glutamate receptor ion channels. Annu. Rev. Physiol. 66, 161-181.
    • (2004) Annu. Rev. Physiol. , vol.66 , pp. 161-181
    • Mayer, M.L.1    Armstrong, N.2
  • 49
    • 0023492484 scopus 로고
    • Permeation and block of N-methyl-D-aspartic acid receptor channels by divalent cations in mouse cultured central neurones
    • Mayer ML and GL Westbrook (1987) Permeation and block of N-methyl-D-aspartic acid receptor channels by divalent cations in mouse cultured central neurones. J. Physiol. 394, 501-527.
    • (1987) J. Physiol. , vol.394 , pp. 501-527
    • Mayer, M.L.1    Westbrook, G.L.2
  • 51
    • 0017905087 scopus 로고
    • Local anaesthetics transiently block currents through single acetylcholine-receptor channels
    • Neher E and JH Steinbach (1978) Local anaesthetics transiently block currents through single acetylcholine-receptor channels. J. Physiol. 277, 153-176.
    • (1978) J. Physiol. , vol.277 , pp. 153-176
    • Neher, E.1    Steinbach, J.H.2
  • 52
    • 0034638256 scopus 로고    scopus 로고
    • N-methyl-D-aspartate receptor subunit changes are associated with lead-induced deficits of long-term potentiation and spatial learning
    • Nihei MK, NL Desmond, JL McGlothan, AC Kuhlmann and TR Guilarte (2000) N-methyl-D-aspartate receptor subunit changes are associated with lead-induced deficits of long-term potentiation and spatial learning. Neuroscience 99, 233-242.
    • (2000) Neuroscience , vol.99 , pp. 233-242
    • Nihei, M.K.1    Desmond, N.L.2    McGlothan, J.L.3    Kuhlmann, A.C.4    Guilarte, T.R.5
  • 54
    • 0030426276 scopus 로고    scopus 로고
    • The sensitivity of N-methyl-D-aspartate receptors to lead inhibition is dependent on the receptor subunit composition
    • Omelchenko IA, CS Nelson, JL Marino and CN Allen (1996) The sensitivity of N-methyl-D-aspartate receptors to lead inhibition is dependent on the receptor subunit composition. J. Pharmacol. Exp. Ther. 278, 15-20.
    • (1996) J. Pharmacol. Exp. Ther. , vol.278 , pp. 15-20
    • Omelchenko, I.A.1    Nelson, C.S.2    Marino, J.L.3    Allen, C.N.4
  • 55
    • 0030931723 scopus 로고    scopus 로고
    • Lead inhibition of N-methyl-D-aspartate receptors containing NR2A, NR2C and NR2D subunits
    • Omelchenko IA, CS Nelson and CN Allen (1997) Lead inhibition of N-methyl-D-aspartate receptors containing NR2A, NR2C and NR2D subunits. J. Pharmacol. Exp. Ther. 282, 1458-1464.
    • (1997) J. Pharmacol. Exp. Ther. , vol.282 , pp. 1458-1464
    • Omelchenko, I.A.1    Nelson, C.S.2    Allen, C.N.3
  • 57
    • 0030746608 scopus 로고    scopus 로고
    • High-affinity zinc inhibition of NMDA NR1-NR2A receptors
    • Paoletti P, P Ascher and J Neyton (1997) High-affinity zinc inhibition of NMDA NR1-NR2A receptors. J. Neurosci. 17, 5711-5725.
    • (1997) J. Neurosci. , vol.17 , pp. 5711-5725
    • Paoletti, P.1    Ascher, P.2    Neyton, J.3
  • 58
    • 0034517709 scopus 로고    scopus 로고
    • Molecular organization of a zinc binding n-terminal modulatory domain in a NMDA receptor subunit
    • Paoletti P, F Perin-Dureau, A Fayyazuddin, A Le Goff, I Callebaut and J Neyton (2000) Molecular organization of a zinc binding n-terminal modulatory domain in a NMDA receptor subunit. Neuron 28, 911-925.
    • (2000) Neuron , vol.28 , pp. 911-925
    • Paoletti, P.1    Perin-Dureau, F.2    Fayyazuddin, A.3    Le Goff, A.4    Callebaut, I.5    Neyton, J.6
  • 59
    • 0037101607 scopus 로고    scopus 로고
    • Mapping the binding site of the neuroprotectant ifenprodil on NMDA receptors
    • Perin-Dureau F, J Rachline, J Neyton and P Paoletti (2002) Mapping the binding site of the neuroprotectant ifenprodil on NMDA receptors. J. Neurosci. 22, 5955-5965.
    • (2002) J. Neurosci. , vol.22 , pp. 5955-5965
    • Perin-Dureau, F.1    Rachline, J.2    Neyton, J.3    Paoletti, P.4
  • 60
    • 0036950527 scopus 로고    scopus 로고
    • Channel gating of NMDA receptors
    • Qian A and JW Johnson (2002) Channel gating of NMDA receptors. Physiol. Behav. 77, 577-582.
    • (2002) Physiol. Behav. , vol.77 , pp. 577-582
    • Qian, A.1    Johnson, J.W.2
  • 62
    • 0033573390 scopus 로고    scopus 로고
    • Distinct synaptic and extrasynaptic NMDA receptors in developing cerebellar granule neurons
    • Rumbaugh G and S Vicini (1999) Distinct synaptic and extrasynaptic NMDA receptors in developing cerebellar granule neurons. J. Neurosci. 19, 10603-10610.
    • (1999) J. Neurosci. , vol.19 , pp. 10603-10610
    • Rumbaugh, G.1    Vicini, S.2
  • 63
    • 0034918208 scopus 로고    scopus 로고
    • Chronic ethanol exposure delays the 'developmental switch' of the NMDA receptor 2A and 2B subunits in cultured cerebellar granule neurons
    • Snell LD, SV Bhave, B Tabakoff and PL Hoffman (2001) Chronic ethanol exposure delays the 'developmental switch' of the NMDA receptor 2A and 2B subunits in cultured cerebellar granule neurons. J. Neurochem. 78, 396-405.
    • (2001) J. Neurochem. , vol.78 , pp. 396-405
    • Snell, L.D.1    Bhave, S.V.2    Tabakoff, B.3    Hoffman, P.L.4
  • 64
    • 0033994387 scopus 로고    scopus 로고
    • alpha(1E) subunits form the pore of three cerebellar R-type calcium channels with different pharmacological and permeation properties
    • Tottene A, S Volsen and D Pietrobon (2000) alpha(1E) subunits form the pore of three cerebellar R-type calcium channels with different pharmacological and permeation properties. J. Neurosci. 20, 171-178.
    • (2000) J. Neurosci. , vol.20 , pp. 171-178
    • Tottene, A.1    Volsen, S.2    Pietrobon, D.3
  • 65
    • 0032529588 scopus 로고    scopus 로고
    • Control of voltage-independent zinc inhibition of NMDA receptors by the NR1 subunit
    • Traynelis SF, MF Burgess, F Zheng, P Lyuboslavsky and JL Powers (1998) Control of voltage-independent zinc inhibition of NMDA receptors by the NR1 subunit. J. Neurosci. 18, 6163-6175.
    • (1998) J. Neurosci. , vol.18 , pp. 6163-6175
    • Traynelis, S.F.1    Burgess, M.F.2    Zheng, F.3    Lyuboslavsky, P.4    Powers, J.L.5
  • 66
    • 0026454799 scopus 로고
    • Developmental change of the inhibition by lead of NMDA-activated currents in cultured hippocampal neurons
    • Ujihara H and EX Albuquerque (1992) Developmental change of the inhibition by lead of NMDA-activated currents in cultured hippocampal neurons. J. Pharmacol. Exp. Ther. 263, 868-875.
    • (1992) J. Pharmacol. Exp. Ther. , vol.263 , pp. 868-875
    • Ujihara, H.1    Albuquerque, E.X.2
  • 67
    • 0031012513 scopus 로고    scopus 로고
    • NMDA receptor heterogeneity during postnatal development of the rat brain: Differential expression of the NR2A, NR2B, and NR2C subunit proteins
    • Wenzel A, JM Fritschy, H Mohler and D Benke (1997) NMDA receptor heterogeneity during postnatal development of the rat brain: differential expression of the NR2A, NR2B, and NR2C subunit proteins. J. Neurochem. 68, 469-478.
    • (1997) J. Neurochem. , vol.68 , pp. 469-478
    • Wenzel, A.1    Fritschy, J.M.2    Mohler, H.3    Benke, D.4
  • 68
    • 0023160323 scopus 로고
    • 2+ antagonize NMDA and GABA responses of hippocampal neurons
    • 2+ antagonize NMDA and GABA responses of hippocampal neurons. Nature 328, 640-643.
    • (1987) Nature , vol.328 , pp. 640-643
    • Westbrook, G.L.1    Mayer, M.L.2
  • 69
    • 0030853492 scopus 로고    scopus 로고
    • Interactions of polyamines with ion channels
    • Williams K (1997) Interactions of polyamines with ion channels. Biochem. J. 325, 289-297.
    • (1997) Biochem. J. , vol.325 , pp. 289-297
    • Williams, K.1
  • 72
    • 0015879604 scopus 로고
    • Ionic blockage of sodium channels in nerve
    • Woodhull AM (1973) Ionic blockage of sodium channels in nerve. J. Gen. Physiol. 61, 687-708.
    • (1973) J. Gen. Physiol. , vol.61 , pp. 687-708
    • Woodhull, A.M.1
  • 73
    • 0029417107 scopus 로고
    • 2+ reduces the current from NMDA receptors expressed in Xenopus oocytes
    • 2+ reduces the current from NMDA receptors expressed in Xenopus oocytes. FEBS Lett. 377, 390-392.
    • (1995) FEBS Lett , vol.377 , pp. 390-392
    • Yamada, Y.1    Ujihara, H.2    Sada, H.3    Ban, T.4
  • 74
    • 0029930662 scopus 로고    scopus 로고
    • Nickel block of a family of neuronal calcium channels: Subtype- and subunit-dependent action at multiple sites
    • Zamponi GW, E Bourinet and TP Snutch (1996) Nickel block of a family of neuronal calcium channels: Subtype- and subunit-dependent action at multiple sites. J. Membr.Biol. 151, 77-90.
    • (1996) J. Membr.Biol. , vol.151 , pp. 77-90
    • Zamponi, G.W.1    Bourinet, E.2    Snutch, T.P.3


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