Gain of allelic gene expression for IGF-II occurs frequently in Barrett's esophagus

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 290, Issue 5, 2006, Pages

  Feagins, Linda A ^a   Susnow, Nathan ^a   Hui, Ying Zhang ^a   Pearson, Stephanie ^a   Owen, Charles ^a   Schmalstieg, William F ^a   Terada, Lance S ^a   Spechler, Stuart J ^a   Ramirez, Ruben D ^a,c   Souza, Rhonda F ^a,b,d  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^d VA NORTH TEXAS HEALTH CARE SYSTEM   (United States)

Author keywords

Gastroesophageal reflux disease; Metaplasia; Polymerase chain reaction

Indexed keywords

COMPLEMENTARY DNA; GENOMIC DNA; SOMATOMEDIN B;

ALLELE; ARTICLE; BARRETT ESOPHAGUS; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE COURSE; DNA DETERMINATION; DNA MODIFICATION; DNA POLYMORPHISM; DUODENUM; ESOPHAGOSCOPY; ESOPHAGUS BIOPSY; ESOPHAGUS CANCER; ESOPHAGUS MUCOSA; EXON; GENE EXPRESSION; GENOME IMPRINTING; HUMAN; HUMAN TISSUE; METAPLASIA; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RESTRICTION MAPPING; STOMACH EPITHELIUM;

ALLELES; BARRETT ESOPHAGUS; EPITHELIUM; ESOPHAGUS; GENE EXPRESSION; HUMANS; INSULIN-LIKE GROWTH FACTOR II; INTESTINES; METAPLASIA; MUCOUS MEMBRANE; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC;

EID: 33645826078     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00383.2005     Document Type: Article

References (29)

1. Baserga R. The IGF-I receptor in cancer research. Exp Cell Res 253: 1-6, 1999.
2. Brito MJ, Filipe MI, Linehan J, and Jankowski J. Association of transforming growth factor α (TGFα) and its precursors with malignant change in Barrett's epithelium: biological and clinical variables. Int J Cancer 60: 27-32, 1995.
3. Cai YC, Yang GY, Nie Y, Wang LD, Zhao X, Song YL, Seril DN, Liao J, Xing EP, and Yang CS. Molecular alterations of p73 in human esophageal squamous cell carcinomas: loss of heterozygosity occurs frequently; loss of imprinting and elevation of p73 expression may be related to defective p53. Carcinogenesis 21: 683-689, 2000.
4. Cruz-Correa M, Cui H, Giardiello FM, Powe NR, Hylind L, Robinson A, Hutcheon DF, Kafonek DR, Brandenburg S, Wu Y, He X, and Feinberg AP. Loss of imprinting of insulin growth factor II gene: a potential heritable biomarker for colon neoplasia predisposition. Gastroenterology 126: 964-970, 2004.
5. Cui H, Cruz-Correa M, Giardiello FM, Hutcheon DF, Kafonek DR, Brandenburg S, Wu Y, He X, Powe NR, and Feinberg AP. Loss of IGF-II imprinting: a potential marker of colorectal cancer risk. Science 299: 1753-1755, 2003.
6. Cui H, Horon IL, Ohlsson R, Hamilton SR, and Feinberg AP. Loss of imprinting in normal tissue of colorectal cancer patients with microsatellite instability. Nat Med 4: 1276-1280, 1998.
7. DeChiara TM, Robertson EJ, and Efstratiadis A. Parental imprinting of the mouse insulin-like growth factor II gene. Cell 64: 849-859, 1991.
8. Feinberg AP. The epigenetics of cancer etiology. Semin Cancer Biol 14: 427-432, 2004.
9. Hofmann WK, Takeuchi S, Frantzen MA, Hoelzer D, and Koeffler HP. Loss of genomic imprinting of insulin-like growth factor 2 is strongly associated with cellular proliferation in normal hematopoietic cells. Exp Hematol 30: 318-323, 2002.
10. L protein expression during the progression of Barrett's neoplasia. Hum Pathol 34: 975-982, 2003.
11. Jankowski J, Hopwood D, and Wormsley KG. Flow-cytometric analysis of growth-regulatory peptides and their receptors in Barrett's oesophagus and oesophageal adenocarcinoma. Scand J Gastroenterol 27: 147-154, 1992.
12. Jirtle RL. IGF-II loss of imprinting: a potential heritable risk factor for colorectal cancer. Gastroenterology 126: 1190-1193, 2004.
13. Kim KS and Lee YI. Biallelic expression of the H19 and IGF-II genes in hepatocellular carcinoma. Cancer Lett 119: 143-148, 1997.
14. Mori M, Inoue H, Shiraishi T, Mimori K, Shibuta K, Nakashima H, Mafune K, Tanaka Y, Ueo H, Barnard GF, Sugimachi K, and Akiyoshi T. Relaxation of insulin-like growth factor 2 gene imprinting in esophageal cancer. Int J Cancer 68: 441-446, 1996.
15. Moschos SJ and Mantzoros CS. The role of the IGF system in cancer: from basic to clinical studies and clinical applications. Oncology 63: 317-332, 2002.
16. Ogawa O, Eccles MR, Szeto J, McNoe LA, Yun K, Maw MA, Smith PJ, and Reeve AE. Relaxation of insulin-like growth factor II gene imprinting implicated in Wilms' tumour. Nature 362: 749-751, 1993.
17. Petley T, Graff K, Jiang W, Yang H, and Florini J. Variation among cell types in the signaling pathways by which IGF-I stimulates specific cellular responses. Horm Metab Res 31: 70-76, 1999.
18. Rainier S, Johnson LA, Dobry CJ, Ping AJ, Grundy PE, and Feinberg AP. Relaxation of imprinted genes in human cancer. Nature 362: 747-749, 1993.
19. Seely BL, Reichart DR, Staubs PA, Jhun BH, Hsu D, Maegawa H, Milarski KL, Saltiel AR, and Olefsky JM. Localization of the insulin-like growth factor I receptor binding sites for the SH2 domain proteins p85, Syp, and GTPase activating protein. J Biol Chem 270: 19151-19157, 1995.
20. Soejima H and Yun K. Allele-specific-polymerase chain reaction: a novel method for investigation of the imprinted insulin-like growth factor II gene. Lab Invest 78: 641-642, 1998.
21. 1 receptor type II mutation in ulcerative colitis-associated neoplasms. Gastroenterology 112: 40-45, 1997.
22. Souza RF, Morales CP, and Spechler SJ. A conceptual approach to understanding the molecular mechanisms of cancer development in Barrett's oesophagus. Aliment Pharmacol Ther 15: 1087-1100, 2001.
23. Souza RF, Shewmake K, Pearson S, Sarosi GA Jr, Feagins LA, Ramirez RD, Terada LS and Spechler SJ. Acid increases proliferation via ERK and p38 MAPK-mediated increases in cyclooxygenase-2 in Barrett's adenocarcinoma cells. Am J Physiol Gastrointest Liver Physiol 287: G743-G748, 2004.
24. Spechler SJ. Clinical practice: Barrett's esophagus. N Engl J Med 346: 836-842, 2002.
25. Toretsky JA and Helman LJ. Involvement of IGF-II in human cancer. J Endocrinol 149: 367-372, 1996.
26. Vorwerk P, Wex H, Bessert C, Hohmann B, Schmidt U, and Mittler U. Loss of imprinting of IGF-II gene in children with acute lymphoblastic leukemia. Leuk Res 27: 807-812, 2003.
27. Woodson K, Flood A, Green L, Tangrea JA, Hanson J, Cash B, Schatzkin A, and Schoenfeld P. Loss of insulin-like growth factor-II imprinting and the presence of screen-detected colorectal adenomas in women. J Natl Cancer Inst 96: 407-410, 2004.
28. Wu MS, Wang HP, Lin CC, Sheu JC, Shun CT, Lee WJ, and Lin JT. Loss of imprinting and overexpression of IGF-II gene in gastric adenocarcinoma. Cancer Lett 120: 9-14, 1997.
29. Yun K, Soejima H, Merrie AE, McCall JL, and Reeve AE. Analysis of IGF-II gene imprinting in breast and colorectal cancer by allele specific-PCR. J Pathol 187: 518-522, 1999.