Variation among cell types in the signaling pathways by which IGF-I stimulates specific cellular responses

Hormone and Metabolic Research

Volumn 31, Issue 2-3, 1999, Pages 70-76

  Petley, T ^a   Graff, K ^a   Jiang, W ^a   Yang, H ^a   Florini, James R ^a  

^a SYRACUSE UNIVERSITY   (United States)

Author keywords

Differentiation; MAP kinase; Mitogenesis; PI 3 kinase; Proliferation

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; SOMATOMEDIN; SOMATOMEDIN RECEPTOR;

ADIPOCYTE; ANIMAL CELL; ARTICLE; BREAST TUMOR; CELL DIFFERENTIATION; CELL METABOLISM; CELL PROLIFERATION; FIBROBLAST; HUMAN; HUMAN CELL; MYOBLAST; NEUROBLASTOMA CELL; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; SKELETAL MUSCLE;

ANIMALIA; MINK CELL FOCUS-FORMING VIRUS;

EID: 0032898811     PISSN: 00185043     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2007-978701     Document Type: Article

References (51)

1. 1. Baserga R, Hongo A, Ribini M, Prisco M, Valentinis B. The IGF-I receptor in cell growth, transformation, and apoptosis. Biochim Biophys Acta 1997; 1332: F105-F126
2. 2. Coolican SA, Samuel DS, Ewton DZ, McWade FJ, Florini JR. The mitogenic and myogenic actions of insulin-like growth factors utilize distinct signaling pathways. J Biol Chem 1997; 272: 12699-702
3. 3. Marshall M. Interactions between Ras and Raf: key regulatory proteins in cellular transformation. Mol Reproduct Devel 1995; 42: 493-9
4. 4. Alessi D, Cuenda A, Cohen P, Dudley D, Saltiel A. PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo. J Biol Chem 1995; 270: 27489-94
5. 5. Yano H, Nakanishi S, Kimura K, Hanai N, Saitoh YU, Fukui Y, Nonomura Y, Matsuda Y, Inhibition of histamine secretion by wortmannin through the blockade of phosphatidylinositol 3-kinase in RBL-2H3 cells. J Biol Chem 1993; 268: 15846-56
6. 6. Kimura D, Hattori S, Kabuyama Y, Shizawa Y, Takayanagi J, Nakamura S, Toki S, Matsuda Y, Onodera K, Fukui Y. Neurite outgrowth of PC12 cells is suppressed by wortmannin, a specific inhibitor of phosphatidylinositol 3-kinase. J Biol Chem 1994; 269: 18961-7
7. 7. Cheatham B, Vlahos CJ, Cheatham L, Wang L, Blenis J, Kahn CR. Phosphatidylinositol 3-kinase activation is required for insulin stimulation of p70 S6 kinase, DNA synthesis, and glucose transporter translocation. Mol Cell Biol 1994; 14: 4902-11
8. 8. Dumont FJ, Su QX. Mechanism of action of the immunosuppressant rapamycin. Life Sci 1995; 58: 373-95
9. S6k by inducing dephosphorylation of the same subset of sites. J Biol Chem 1995; 270: 21396-403
10. 10. Beretta L, Gingras AC, Svitkin YV, Hall MN, Sonenberg N. Rapamycin blocks the phosphorylation of 4E-BP1 and inhibits cap-dependent initiation of translation. EMBO J 1996; 15: 658-64
11. S6k. EMBO J 1997; 16: 3693-704
12. 12. Pinset C, Garcia A, Rousse S, Dubois C, Montarras D. Wortmannin inhibits IGF-dependent differentiation in the mouse myogenic cell line C2. Compt Rendu Acad Sci Paris 1997; 320: 367-74
13. 13. Mangiacapra FJ, Roof SL, Ewton DZ, Florini JR. Paradoxical decrease in myf-5 MRNA levels during induction of myogenic differentiation by IGFs. Mol Endocrinol 1992; 6: 2038-44
14. 14. Scrimgeour AG, Beitner-Johnson D, LeRoith D. Chronic exposure to IGF-I increases Raf-1 levels in NIH 3T3 cells. Abstr 77th Ann Mtg, the Endocrine Soc 1995; P3-1: 514
15. 15. Lenormand P, McMahon M, Pouyssegur J. Oncogenic Raf-1 activates p70 S6 kinase via a mitogen-activated protein kinase-independent pathway. J Biol Chem 1996; 271: 15762-8
16. 16. Kuo W, Abe M, Rhee J, Eves E, McCarthy S, Yan M, Templeton D, McMahon M, Rosner M. Raf, but not MEK or ERK, is sufficient for differentiation of hippocampal neuronal cells. Mol Cell Biol 1996; 16: 1458-70
17. 17. Samuel DS, Ewton DZ, Coolican SA, Petley TD, McWade FJ, Florini JR. Raf-1 activation stimulates proliferation and inhibits IGF-stimulated differentiation in L6A1 myoblasts. Horm Metab Res 1999; 31: 55-64
18. 18. Kaliman P, Canicio J, Shepherd PR, Beetson CA, Testar X, Palacin M, Zorzano A. Insulin-like growth factors require phosphatidylinositol 3-kinase to signal myogenesis: Dominant negative p85 expression blocks differentiation of L6E9 muscle cells. Mol Endocrinol 1998; 12: 66-77
19. 19. Myers MG Jr, Sun XJ, Cheatham B, Jachna BR, Glasheen EM, Backer JM, White MF. IRS-1 is a common element in insulin and insulin-like growth factor-I signaling to the phosphatidylinositol 3′-kinase. Endocrinology 1993; 132: 1421-30
20. 20. Giorgino F, Smith RJ. Dexamethasone enhances insulin-like growth factor-I effects on skeletal muscle cell proliferation. Role of specific intracellular signaling pathways. J Clin Invest 1995; 96: 1473-83
21. 21. Hara K, Yonezawa K, Sakau H, Ando A, Kotani K, Kitamura T, Ueda H, Stephens L, Jackson TR, Kasuga M. 1-PI3-kinase is required for insulin-stimulated glucose trnasport but not for Raf activation in CHO cells. Proc Natl Acad Sci USA 1994; 91: 7415-19
22. 22. Ewton DZ, Roof SL, Magri KA, McWade FJ, Florini JR. IGF-II is more active than IGF-I in stimulating L6A1 myogenesis: Greater mitogenic actions of IGF-I delay differentiation. J Cell Physiol 1994; 161: 277-84
23. 23. Engert JC, Berglund EB, Rosenthal N. Proliferation precedes differentiation in IGF-I-stimulated myogenesis. J Cell Biol 1996; 135: 431-40
24. 24. Takahashi Y, Toke K, Kadowaki H, Katsumata D, Fukushima Y, Yazaki Y, Akanuma Y, Kadowaki T. Roles of insulin receptor substrate-1 and shc on insulin-like growth factor receptor signaling in early passages of cultured human fibroblasts. Endocrinology 1997; 138: 741-50
25. 25. Taylor SI. Molecular mechanism of insulin resistance. Lessons from patients with mutations in the insulin receptor gene. Diabetes 1992; 41: 1473-90
26. 26. Smith P, Wise LS, Berkowitz R, Wan C, Rubin CS. Insulin-like growth factor-I is an essential regulator of the differentiation of 3T3-L1 adipocytes.J Biol Chem 1988; 263: 9402-8
27. 27. Porras A, Nebreda AR, Benito M, Santos E. Activation of Raf by insulin in 3T3-L1 cells does not involve GTPase-activating protein phosphorylation. J Biol Chem 1992; 2678: 21124-31
28. 28. Porras A, Muszynski K, Rapp RR, Santos E. Dissociation between activation of Raf-1 kinase and the 42-kDa mitogen-activated protein kinase/90-kDa S6 kinase cascade in the insulin/Ras pathway of adipocyte differentiation in 3T3-L. J Biol Chem 1994; 269: 12741-8
29. 29. Tomiyama K, Nakata H, Sasa H, Arimura S, Nishio E, Watanabe Y. Wortmannin, a specific phosphatidylinositol 3-kinase inhibitor, inhibits adipocytic differentiation of 3T3 L1 cells. Biochem Biophys Res Comm 1995; 212: 263-9
30. 30. Sale EM, Atkinson GP, Sale GJ. Requirement of MAP kinase for differentiation of fibroblasts to adipocytes, for insulin activation of p90 S6 kinase, and for insulin or serum stimulation of DNA synthesis. EMBO J 1995; 14: 674-84
31. 31. De Mora JF, Porras A, Ahn N, Santos E. Mitogen-activated protein kinase activation is not necessary for, but antagonizes, 3T3-L1 adipocytic differentiation. Mol Cell Biol 1997; 17: 6068-75
32. 32. Lorenzo M, Valverde AM, Teruel T, Benito M. IGF-I is a mitogen also involved in differentiation-related gene expression in fetal rat brown adipocytes. J Cell Biol 1993; 123: 1567-75
33. 33. Valverde AM, Benito M, Lorenzo M. Proliferation of fetal brown adipocyte primary cultures: Relationship with the genetic expression of glucose-6-phosphate dehydrogenase. Exp Cell Res 1991; 194: 232-7
34. 34. Valverde AM, Lorenzo M, Teruel T, Benito M. cAMP inhibits IGF-I-induced mitogenesis in fetal rat brown adipocytes: Roleof p21 Raf. Exp Cell Res 1995; 218: 305-9
35. 35. Valverde AM, Teruel T, Lorenzo M, Benito M. Involvement of Raf-1 kinase and protein kinase C-zeta in insulin-like growth factor I-induced brown adipocyte mitogenic signaling cascades: Inhibition by cAMP. Endocrinology 1996; 137: 3832-41
36. 36. Valverde AM, Lorenzo M, Navarro P, Benito M. Phosphatidylinositol 3-kinase is a requirement for insulin-like growth factor I-induced differentiation, but not for mitogenesis, in fetal brown adipocytes. Mol Endocrinol 1997; 11: 595-607
37. 37. Teruel T, Valverde AM, Benito M, Lorenzo M. Insulin-like growth factor I and insulin induce adipogenic-related gene expression in foetal brown adipocyte primary cultures. Biochem J 1996; 319: 627-32
38. 38. Huff KK, Kaufman D, Gabbay KH, Spencer EM, Lippman ME, Dickson RB. Secretion of an insulin-like growth factor-I-related protein by human breast cancer cells. Cancer Res 1986; 46: 4613-9
39. 39. Chao TS, Foster DA, Rapp UR, Rosner MR. Differential Raf requirement for activation of mitogen-activated protein kinase by growth factors, phorbol esters, and calcium. J Biol Chem 1994; 269: 7337-41
40. 40. Chakravorty A, Joslyn MI, Davis JS. Characterization of insulin and insulin-like growth factor-I actions in the bovine luteal cell: Receptor tyrosine kinase activity, PI 3-kinase, and DNA synthesis. Endocrinology 1993; 133: 1331-40
41. 41. Dufourny B, Alblas J, van Teeffelen H, van Schaik F, van der Burg B, Steenbergh P, Sussenbach J. Mitogenic signaling of insulin-like growth factor I in MCF-7 human breast cancer cells requires phosphatidylinositol 3-kinase and is independent of mitogen-activated protein kinase. J Biol Chem 1997; 272: 31163-71
42. 42. Albas J, Slager-Davidov R, Steenbergh PhH, Sussenbach JS, van der Burg B. The role of MAP kinase in TPA-mediated cell cycle arrest of human breast cancer cells. Oncogene 1998; 16: 131-9
43. 43. Guvakova MA, Surmacz E. Tamoxifen interferes with the insulin-like grwoth factor I receptor (IGF-IR) signaling pathway in breast cancer cells. Cancer Res 1997; 57: 2606-10
44. 44. Kim B, Leventhal PS, Saltiel AR, Feldman EL. Insulin-like growth factor-I-mediated neurite outgrowth in vitro requires mitogen-activated protein kinase activation. J Biol Chem 1997; 272: 21268-73
45. 45. Lavenius E, Parrow V, Nanbert E, Pahlman S. Basic FGF and IGF-I promote differentiation of human SH-SY5Y neuroblastoma cells in culture. Growth Factors 1994; 10: 29-39
46. 46. Sumantran VN, Feldman EL. Insulin-like growth factor I regulates c-myc and BAP-43 messenger ribonucleic acid expression on SH-SY5Y human neuroblastoma cells. Endocrinology 1993; 132: 2017-23
47. 47. Pahlman S, Meyerson G, Lingren E, Shalling M, Hohansson I. Insulin-like growth factor I shifts from promoting cell division to potentiating maturation during neuronal differentiation. Proc Natl Acad Sci USA 1991; 88: 9994-8
48. 48. Recio-Pinto E, Ishii DN. Effects of insulin, insulin-like growth factor II, and neural growth factor on neurite outgrowth in cultured human neuroblastoma cells. Brain Res 1984; 302: 323-34
49. 49. Liu Q, Schacher D, Hurth C, Freund GG, Dantzer R, Kelley KW. Activation of phosphatidylinositol 3′-kinase by insulin-like growth factor-I rescues promyeloid cells from apoptosis and permits their differentiation into granulocytes. J Immunol 1997; 159: 829-37
50. 50. Kanda S, Hodgkin MM, Woodfield RJ, Wakelam MJO, Thomas G, Claesson-Welsh L. Phosphatidylinositol 3′-kinase-independent p70 S6 kinase activation by fibroblast growth factor receptor-1 is important for proliferation but not differentiation of endothelial cells. J Biol Chem 1997; 272: 23347-53
51. 51. Scrimgeour AG, Blakesley VA, Stannard BS, LeRoith D. Mitogen-activated protein kinase and phosphatidylinositol 3-kinase are not sufficient for insulin-like growth factor 1-induced mitogenesisand tumorigenesis. Endocrinol 1997; 138: 2552-8