Proteomic analysis of iron overload in human hepatoma cells

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 290, Issue 5, 2006, Pages

  Petrak, Jiri ^a,b   Myslivcova, Denisa ^a   Man, Petr ^a   Cmejla, Radek ^a   Cmejlova, Jana ^a   Vyoral, Daniel ^a  

^a CHARLES UNIVERSITY   (Czech Republic)

^b INSTITUTE OF HEMATOLOGY AND BLOOD TRANSFUSION   (Czech Republic)

Author keywords

Liver; Proteomics

Indexed keywords

IRON; PROTEIN; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

ARTICLE; CELL CYCLE REGULATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENERGY METABOLISM; GENE EXPRESSION; HEPATOMA CELL; HUMAN; HUMAN CELL; IRON OVERLOAD; IRON STORAGE; LIPID PEROXIDATION; LIVER CELL CARCINOMA; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEOMICS; STRESS; TWO DIMENSIONAL ELECTROPHORESIS; UPREGULATION;

ALDEHYDE DEHYDROGENASE; AMINO ACID SEQUENCE; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CLUSTER ANALYSIS; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; GENE EXPRESSION PROFILING; HUMANS; IRON OVERLOAD; LIPID PEROXIDATION; LIVER; MASS SPECTROMETRY; MOLECULAR SEQUENCE DATA; OXIDATIVE STRESS; PROTEOMICS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 33645813628     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00469.2005     Document Type: Article

References (40)

1. Bacon BR, O'Neill R, and Britton RS. Hepatic mitochondrial energy production in rats with chronic iron overload. Gastroenterology 105: 1134-1140, 1993.
2. Britton RS, O'Neill R, and Bacon BR. Hepatic mitochondrial malondialdehyde metabolism in rats with chronic iron overload. Hepatology 11: 93-97, 1990.
3. Cadenas E. Biochemistry of oxygen toxicity. Annu Rev Biochem 58: 79-110, 1989.
4. Carrard G, Bulteau AL, Petropoulos I, and Friguet B. Impairment of proteasome structure and function in aging. Int J Biochem Cell Biol 34: 1461-1474, 2002.
5. Durany N, Joseph J, Campo E, Molina R, and Carreras J. Phosphoglycerate mutase, 2,3-bisphosphoglycerate phosphatase and enolase activity and isoenzymes in lung, colon and liver carcinomas. Br J Cancer 75: 969-77, 1997.
6. Esterbauer H and Cheeseman KH. Determination of aldehyde lipid peroxidation products: malonaldehyde and 4-hydroxynonenal. Methods Enzymol 186: 407-421, 1990.
7. Friedman JR, Fredericks WJ, Jensen DE, Speicher DW, Huang XP, Neilson EG, and Rauscher FJ 3rd. KAP-1, a novel corepressor for the highly conserved KRAB repression domain. Genes Dev 10: 2067-2078, 1996.
8. Goldman RD, Gruenbaum Y, Moir RD, Shumaker DK, and Spann TP. Nuclear lamins: building blocks of nuclear architecture. Genes Dev 16: 533-547, 2002.
9. Hall PA and Russell SE. The pathobiology of the septin gene family. J Pathol 204: 489-505, 2004.
10. Hentze MW, Muckenthaler MU, and Andrews NC. Balancing acts: molecular control of mammalian iron metabolism. Cell 117: 285-297, 2004.
11. Hjelle JJ, Grubbbs JH, and Petersen DR. Inhibition of mitochondrial aldehyde dehydrogenase by malondialdehyde. Toxicol Lett 14: 35-43, 1982.
12. Kikuchi M, Doi E, Tsujimoto I, Horibe T, and Tsujimoto Y. Functional analysis of human P5, a protein disulfide isomerase homologue. J Biochem (Tokyo) 132: 451-455, 2002.
13. Kowdley KV. Iron, hemochromatosis, and hepatocellular carcinoma. Gastroenterology 127: S79-S86, 2004.
14. Ku NO, Darling JM, Krams SM, Esquivel CO, Keeffe EB, Sibley RK, Lee YM, Wright TL, and Omary MB. Keratin 8 and 18 mutations are risk factors for developing liver disease of multiple etiologies. Proc Natl Acad Sci USA 100: 6063-6068, 2003.
15. Li Z, Wang D, Na X, Schoen SR, Messing EM, and Wu G. The VHL protein recruits a novel KRAB-A domain protein to repress HIF-1α transcriptional activity. EMBO J 22: 1857-1867, 2003.
16. Mates JM, Segura JM, Perez-Gomez C, Rosado R, Olalla L, Blanca M, and Sanchez-Jimenez FM. Antioxidant enzymatic activities in human blood cells after an allergic reaction to pollen or house dust mite. Blood Cells Mol Dis 25: 103-109, 1999.
17. Noiva R and Lennarz WJ. Protein disulfide isomerase. A multifunctional protein resident in the lumen of the endoplasmic reticulum. J Biol Chem 267: 3553-3556, 1992.
18. Ohsawa I, Nishimaki K, Yasuda C, Kamino K, and Ohta S. Deficiency in a mitochondrial aldehyde dehydrogenase increases vulnerability to oxidative stress in PC12 cells. J Neurochem 84: 1110-1117, 2003.
19. Okada K, Wangpoengtrakul C, Osawa T, Toyokuni S, Tanaka K, and Uchida K. 4-Hydroxy-2-nonenal-mediated impairment of intracellular proteolysis during oxidative stress: identification of proteasomes as target molecules. J Biol Chem 274: 23787-23793, 1999.
20. Omary MB, Ku NO, and Toivola DM. Keratins: guardians of the liver. Hepatology 35: 251-257, 2002.
21. Pietrangelo A. Iron-induced oxidant stress in alcoholic liver fibrogenesis. Alcohol 30: 121-129, 2003.
22. Pollard MG, Travers KJ, and Weissman JS. Ero1p: a novel and ubiquitous protein with an essential role in oxidative protein folding in the endoplasmic reticulum. Mol Cell 1: 171-182, 1998.
23. Roth J, Ziak M, and Zuber C. The role of glucosidase II and endo-mannosidase in glucose trimming of asparagine-linked oligosaccharides. Biochimie 85: 287-294, 2003.
24. Ryan RF, Schultz DC, Ayyanathan K, Singh PB, Friedman JR, Fredericks WJ, and Rauscher FJ 3rd. KAP-1 corepressor protein interacts and colocalizes with heterochromatic and euchromatic HP1 proteins: a potential role for Kruppel-associated box-zinc finger proteins in heterochromatin-mediated gene silencing. Mol Cell Biol 19: 4366-4378, 1999.
25. Saheki T and Kobayashi K. Mitochondrial aspartate glutamate carrier (citrin) deficiency as the cause of adult-onset type II citrullinemia (CTLN2) and idiopathic neonatal hepatitis (NICCD). J Hum Genet 47: 333-341, 2002.
26. Santoni V, Molloy M, and Rabilloud T. Membrane proteins and proteomics: un amour impossible? Electrophoresis 21: 1054-1070, 2000.
27. Shibayama H, Takai E, Matsumura I, Kouno M, Morii E, Kitamura Y, Takeda J, and Kanakura Y. Identification of a cytokine-induced antiapoptotic molecule anamorsin essential for definitive hematopoiesis. J Exp Med 199: 581-592, 2004.
28. Strey CW, Winters MS, Markiewski MM, and Lambris JD. Partial hepatectomy induced liver proteome changes in mice. Proteomics 5: 318-325, 2005.
29. Su Q, Fu Y, Liu YF, Zhang W, Liu J, and Wang CM. Laminin induces the expression of cytokeratin 19 in hepatocellular carcinoma cells growing in culture. World J Gastroenterol 9: 921-929, 2003.
30. Toivola DM, Ku NO, Resurreccion EZ, Nelson DR, Wright TL, and Omary MB. Keratin 8 and 18 hyperphosphorylation is a marker of progression of human liver disease. Hepatology 40: 459-466, 2004.
31. Underhill C, Qutob MS, Yee SP, and Torchia J. A novel nuclear receptor corepressor complex, N-CoR, contains components of the mammalian SWI/SNF complex and the corepressor KAP-1. J Biol Chem 275: 40463-40470, 2000.
32. Vuori K, Pihlajaniemi T, Marttila M, and Kivirikko KI. Characterization of the human prolyl 4-hydroxylase tetramer and its multifunctional protein disulfide-isomerase subunit synthesized in a baculovirus expression system. Proc Natl Acad Sci USA 89: 7467-7470, 1992.
33. Wilkinson B and Gilbert HF. Protein disulfide isomerase. Biochim Biophys Acta 1699: 35-44, 2004.
34. Wu F, Nishioka M, Fujita J, Murota M, Ohtsuki Y, Ishida T, and Kuriyama S. Expression of cytokeratin 19 in human hepatocellular carcinoma cell lines. Int J Oncol 20: 31-37, 2002.
35. Ye Z and Connor JR. Identification of iron responsive genes by screening cDNA libraries from suppression subtractive hybridization with antisense probes from three iron conditions. Nucleic Acids Res 28: 1802-1807, 200.
36. Zaman K, Ryu H, Hall D, O'Donovan K, Lin KI, Miller MP, Marquis JC, Baraban JM, Semenza GL, and Ratan RR. Protection from oxidative stress-induced apoptosis in cortical neuronal cultures by iron chelators is associated with enhanced DNA binding of hypoxia-inducible factor-1 and ATF-1/CREB and increased expression of glycolytic enzymes, p21waf1/cip1, and erythropoietin. J Neurosci 19: 9821-9830, 1999.
37. Zatloukal K, Stumptner C, Lehner M, Denk H, Baribault H, Eshkind LG, and Franke WW. Cytokeratin 8 protects from hepatotoxicity, and its ratio to cytokeratin 18 determines the ability of hepatocytes to form Mallory bodies. Am J Pathol 156: 1263-1274, 2000.
38. Zhong B and Omary MB. Actin overexpression parallels severity of pancreatic injury. Exp Cell Res 299: 404-414, 2004.
39. Zhou Q, Ji X, Chen L, Greenberg HB, Lu SC, and Omary MB. Keratin mutation primes mouse liver to oxidative injury. Hepatology 41: 517-525, 2005.
40. Zhu WG, Roberts ZV, and Dynlacht JR. Heat-induced modulation of lamin B content in two different cell lines. J Cell Biochem 75: 620-628, 1999.