Stem cell aging: What bleach can teach

Nature Medicine

Volumn 12, Issue 4, 2006, Pages 383-384

  Liu, Jie ^a   Finkel, Toren ^a  

^a NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATM PROTEIN; BUTHIONINE SULFOXIMINE; DEOXYRIBONUCLEOPROTEIN; FREE RADICAL; MITOGEN ACTIVATED PROTEIN KINASE P38; OXIDIZING AGENT; REACTIVE OXYGEN METABOLITE;

BLEACHING; BONE MARROW DEPRESSION; CELL AGING; CELL PROLIFERATION; CELL SURVIVAL; CYTOLOGY; DNA DAMAGE; GENETIC ANALYSIS; HEMATOPOIETIC STEM CELL; HUMAN; INTRACELLULAR SPACE; NONHUMAN; PRIORITY JOURNAL; SHORT SURVEY; STEM CELL; STEM CELL TRANSPLANTATION; STRESS; WILD TYPE;

ANIMALS; BUTHIONINE SULFOXIMINE; CELL AGING; CELL CYCLE PROTEINS; CELL PROLIFERATION; DNA-BINDING PROTEINS; ENZYME ACTIVATION; ENZYME INHIBITORS; HEMATOPOIETIC STEM CELLS; HYDROGEN PEROXIDE; MICE; MODELS, BIOLOGICAL; OXIDANTS; OXIDATION-REDUCTION; OXIDATIVE STRESS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEINS;

EID: 33645730025     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm0406-383     Document Type: Short Survey

References (12)

1. Harman, D. J. Gerontol. 11, 298-300 (1956).
2. Balaban, R.S., Nemoto, S. & Finkel, T. Cell 120, 483-495 (2005).
3. Ito, K et al. Nat. Med. 12, 446-451 (2006).
4. Ito, K. et al. Nature 431, 997-1002 (2004).
5. Rotman, G. & Shiloh, Y. Bioessays 19, 911-917 (1997).
6. Schubert, R. et al. Hum. Mol. Genet. 13, 1793-1802 (2004).
7. Cheng, T. et al. Science 287, 1804-1808 (2000).
8. Tonks, N.K. Cell 121, 667-670 (2005).
9. Sundaresan, M., Yu, Z.X., Ferrans, V.J., Irani, K. & Finkel, T. Science 270, 296-9 (1995).
10. Park, I.K. et al. Nature 423, 302-305 (2003).
11. Voncken, J.W. et al. J. Biol. Chem. 280, 5178-5187 (2005).
12. Pagano, G. et al. Eur. J. Haematol. 75, 93-100 (2005).