Benzoylphenylurea sulfur analogues with potent antitumor activity

Journal of Medicinal Chemistry

Volumn 49, Issue 7, 2006, Pages 2357-2360

  Hallur, Gurulingappa ^a   Jimeno, Antonio ^a   Dalrymple, Susan ^a   Zhu, Tao ^a   Jung, M Katherine ^c   Hidalgo, Manuel ^a   Isaacs, John T ^a   Sukumar, Saraswati ^a   Hamel, Ernest ^b   Khan, Saeed R ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c SAIC FREDERICK INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 (2 AMINOBENZOYL) 3 [4 (5 BROMOPYRIMIDIN 2 YLSULFANYL)PHENYL]UREA; 1 [4 (5 BROMOPYRIMIDIN 2 YLSULFANYL)PHENYL] 3 (2 NITROBENZOYL)UREA; ANTINEOPLASTIC AGENT; CARBANILAMIDE DERIVATIVE; NSC 639829; SULFUR DERIVATIVE; TUBULIN; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER; CANCER CELL CULTURE; CELL STRAIN MCF 7; CULTURE MEDIUM; DRUG EFFICACY; DRUG MECHANISM; DRUG POTENCY; DRUG SYNTHESIS; EVALUATION; HUMAN; HUMAN CELL; IC 50; MICROTUBULE ASSEMBLY; REACTION ANALYSIS;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; PHENYLUREA COMPOUNDS; PYRIMIDINES; STRUCTURE-ACTIVITY RELATIONSHIP; TUBULIN MODULATORS;

EID: 33645693801     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm051261s     Document Type: Article

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