메뉴 건너뛰기




Volumn 77, Issue 4, 2006, Pages 489-494

Increased thalamus levels of glutamate and glutamine (Glx) in patients with idiopathic generalised epilepsy

Author keywords

[No Author keywords available]

Indexed keywords

GLUTAMIC ACID; GLUTAMINE; N ACETYLASPARTIC ACID;

EID: 33645562377     PISSN: 00223050     EISSN: 1468330X     Source Type: Journal    
DOI: 10.1136/jnnp.2005.074682     Document Type: Article
Times cited : (83)

References (40)
  • 1
    • 0024317220 scopus 로고
    • Proposal for revised classification of epilepsies and epileptic syndromes
    • Commission on Classification and Terminology of the International League Against Epilepsy
    • Proposal for revised classification of epilepsies and epileptic syndromes. Commission on Classification and Terminology of the International League Against Epilepsy. Epilepsia 1989;30(4):389-99.
    • (1989) Epilepsia , vol.30 , Issue.4 , pp. 389-399
  • 2
  • 4
    • 0031732075 scopus 로고    scopus 로고
    • Spike-wave complexes and fast components of cortically generated seizures. I. Role of neocortex and thalamus
    • Steriade M, Contreras D. Spike-wave complexes and fast components of cortically generated seizures. I. Role of neocortex and thalamus. J Neurophysiol 1998;80(3):1439-55.
    • (1998) J Neurophysiol , vol.80 , Issue.3 , pp. 1439-1455
    • Steriade, M.1    Contreras, D.2
  • 5
    • 0026611825 scopus 로고
    • Cortical and thalamic lesions in rats with genetic absence epilepsy
    • Vergnes M, Marescaux C. Cortical and thalamic lesions in rats with genetic absence epilepsy. J Neural Transm Suppl 1992;35:71-83.
    • (1992) J Neural Transm Suppl , vol.35 , pp. 71-83
    • Vergnes, M.1    Marescaux, C.2
  • 6
    • 0020065183 scopus 로고
    • Interaction of cortex and thalamus in spike and wave discharges of feline generalized penicillin epilepsy
    • Avoli M, Gloor P. Interaction of cortex and thalamus in spike and wave discharges of feline generalized penicillin epilepsy. Exp Neurol 1982;76(1):196-217.
    • (1982) Exp Neurol , vol.76 , Issue.1 , pp. 196-217
    • Avoli, M.1    Gloor, P.2
  • 7
    • 0036925413 scopus 로고    scopus 로고
    • Thalamocortical oscillations in a genetic model of absence seizures
    • D'Arcangelo G, D'Antuono M, Biagini G, et al. Thalamocortical oscillations in a genetic model of absence seizures. Eur J Neurosci 2002;16(12):2383-93.
    • (2002) Eur J Neurosci , vol.16 , Issue.12 , pp. 2383-2393
    • D'Arcangelo, G.1    D'Antuono, M.2    Biagini, G.3
  • 8
    • 0030540949 scopus 로고    scopus 로고
    • Cortical versus thalamic mechanisms underlying spike and wave discharges in GAERS
    • Avanzini G, de Curtis M, Franceschetti S, et al. Cortical versus thalamic mechanisms underlying spike and wave discharges in GAERS. Epilepsy Res 1996;26(1):37-44.
    • (1996) Epilepsy Res , vol.26 , Issue.1 , pp. 37-44
    • Avanzini, G.1    De Curtis, M.2    Franceschetti, S.3
  • 9
    • 1642559335 scopus 로고    scopus 로고
    • MRS shows syndrome differentiated metabolite changes in human-generalized epilepsies
    • Savic I, Osterman Y, Helms G. MRS shows syndrome differentiated metabolite changes in human-generalized epilepsies. Neuroimage 2004;21(1):163-72.
    • (2004) Neuroimage , vol.21 , Issue.1 , pp. 163-172
    • Savic, I.1    Osterman, Y.2    Helms, G.3
  • 10
    • 0142184242 scopus 로고    scopus 로고
    • Magnetic resonance spectroscopy and imaging of the thalamus in idiopathic generalized epilepsy
    • Bernasconi A, Bernasconi N, Natsume J, et al. Magnetic resonance spectroscopy and imaging of the thalamus in idiopathic generalized epilepsy. Brain 2003;126(Pt 11):2447-54.
    • (2003) Brain , vol.126 , Issue.PART 11 , pp. 2447-2454
    • Bernasconi, A.1    Bernasconi, N.2    Natsume, J.3
  • 11
    • 0242407511 scopus 로고    scopus 로고
    • Thalamic dysfunction in juvenile myoclonic epilepsy: A proton MRS study
    • Mory SB, Li LM, Guerreiro CA, et al. Thalamic dysfunction in juvenile myoclonic epilepsy: a proton MRS study. Epilepsia 2003;44(11):1402-5.
    • (2003) Epilepsia , vol.44 , Issue.11 , pp. 1402-1405
    • Mory, S.B.1    Li, L.M.2    Guerreiro, C.A.3
  • 12
    • 0035061959 scopus 로고    scopus 로고
    • Idiopathic generalized epilepsy with generalized and other seizures in adolescence
    • Andermann F, Berkovic SF. Idiopathic generalized epilepsy with generalized and other seizures in adolescence. Epilepsia 2001;42(3):317-20.
    • (2001) Epilepsia , vol.42 , Issue.3 , pp. 317-320
    • Andermann, F.1    Berkovic, S.F.2
  • 13
    • 0031985750 scopus 로고    scopus 로고
    • Regional metabolite concentrations in human brain as determined by quantitative localized proton MRS
    • Pouwels PJ, Frahm J. Regional metabolite concentrations in human brain as determined by quantitative localized proton MRS. Magn Reson Med 1998;39(1):53-60.
    • (1998) Magn Reson Med , vol.39 , Issue.1 , pp. 53-60
    • Pouwels, P.J.1    Frahm, J.2
  • 14
    • 0034006960 scopus 로고    scopus 로고
    • MR spectroscopy shows reduced frontal lobe concentrations of N-acetyl aspartate in patients with juvenile myoclonic epilepsy
    • Savic I, Lekvall A, Greitz D, et al. MR spectroscopy shows reduced frontal lobe concentrations of N-acetyl aspartate in patients with juvenile myoclonic epilepsy. Epilepsia 2000;41(3):290-6.
    • (2000) Epilepsia , vol.41 , Issue.3 , pp. 290-296
    • Savic, I.1    Lekvall, A.2    Greitz, D.3
  • 15
    • 0034900222 scopus 로고    scopus 로고
    • Restoration of motion-related signal loss and line-shape deterioration of proton MR spectra using the residual water as intrinsic reference
    • Helms G, Piringer A. Restoration of motion-related signal loss and line-shape deterioration of proton MR spectra using the residual water as intrinsic reference. Magn Reson Med 2001;46(2):395-400.
    • (2001) Magn Reson Med , vol.46 , Issue.2 , pp. 395-400
    • Helms, G.1    Piringer, A.2
  • 16
    • 0027375098 scopus 로고
    • Estimation of metabolite concentrations from localized in vivo proton NMR spectra
    • Provencher SW. Estimation of metabolite concentrations from localized in vivo proton NMR spectra. Magn Reson Med 1993;30(6):672-9.
    • (1993) Magn Reson Med , vol.30 , Issue.6 , pp. 672-679
    • Provencher, S.W.1
  • 17
    • 0034537605 scopus 로고    scopus 로고
    • A precise and user-independent quantification technique for regional comparison of single volume proton MR spectroscopy of the human brain
    • Helms G. A precise and user-independent quantification technique for regional comparison of single volume proton MR spectroscopy of the human brain. NMR Biomed 2000;13(7):398-406.
    • (2000) NMR Biomed , vol.13 , Issue.7 , pp. 398-406
    • Helms, G.1
  • 18
    • 0034431849 scopus 로고    scopus 로고
    • Stereotaxic display of brain lesions
    • Rorden C, Brett M. Stereotaxic display of brain lesions. Behav Neurol 2000;12(4):191-200.
    • (2000) Behav Neurol , vol.12 , Issue.4 , pp. 191-200
    • Rorden, C.1    Brett, M.2
  • 21
    • 0034973141 scopus 로고    scopus 로고
    • A voxel-based morphometric study of ageing in 465 normal adult human brains
    • Good CD, Johnsrude IS, Ashburner J, et al. A voxel-based morphometric study of ageing in 465 normal adult human brains. Neuroimage 2001;14(1 Pt 1):21-36.
    • (2001) Neuroimage , vol.14 , Issue.1 PART 1 , pp. 21-36
    • Good, C.D.1    Johnsrude, I.S.2    Ashburner, J.3
  • 22
    • 0030668370 scopus 로고    scopus 로고
    • Multimodal image coregistration and partitioning - A unified framework
    • Ashburner J, Friston K. Multimodal image coregistration and partitioning-a unified framework. Neuroimage 1997;6(3):209-17.
    • (1997) Neuroimage , vol.6 , Issue.3 , pp. 209-217
    • Ashburner, J.1    Friston, K.2
  • 23
    • 0032970425 scopus 로고    scopus 로고
    • Nonlinear spatial normalization using basis functions
    • Ashburner J, Friston KJ. Nonlinear spatial normalization using basis functions. Hum Brain Mapp 1999;7(4):254-66.
    • (1999) Hum Brain Mapp , vol.7 , Issue.4 , pp. 254-266
    • Ashburner, J.1    Friston, K.J.2
  • 24
    • 0033933649 scopus 로고    scopus 로고
    • Voxel-based morphometry - The methods
    • Ashburner J, Friston KJ. Voxel-based morphometry-the methods. Neuroimage 2000;11(6 Pt 1):805-21.
    • (2000) Neuroimage , vol.11 , Issue.6 PART 1 , pp. 805-821
    • Ashburner, J.1    Friston, K.J.2
  • 25
    • 0033059273 scopus 로고    scopus 로고
    • Short echo time single-voxel 1H magnetic resonance spectroscopy in magnetic resonance imaging-negative temporal lobe epilepsy: Different biochemical profile compared with hippocampal sclerosis
    • Woermann FG, McLean MA, Bartlett PA, et al. Short echo time single-voxel 1H magnetic resonance spectroscopy in magnetic resonance imaging-negative temporal lobe epilepsy: different biochemical profile compared with hippocampal sclerosis. Ann Neurol 1999;45(3):369-76.
    • (1999) Ann Neurol , vol.45 , Issue.3 , pp. 369-376
    • Woermann, F.G.1    McLean, M.A.2    Bartlett, P.A.3
  • 26
    • 0141924732 scopus 로고    scopus 로고
    • Proton MRS reveals frontal lobe metabolite abnormalities in idiopathic generalized epilepsy
    • Simister RJ, McLean MA, Barker GJ, et al. Proton MRS reveals frontal lobe metabolite abnormalities in idiopathic generalized epilepsy. Neurology 2003;61(7):897-902.
    • (2003) Neurology , vol.61 , Issue.7 , pp. 897-902
    • Simister, R.J.1    McLean, M.A.2    Barker, G.J.3
  • 27
    • 0032877337 scopus 로고    scopus 로고
    • Analysis of 1.5 Tesla proton MR spectra of human brain using LCModel and an imported basis set
    • Helms G. Analysis of 1.5 Tesla proton MR spectra of human brain using LCModel and an imported basis set. Magn Reson Imaging 1999;17(8):1211-8.
    • (1999) Magn Reson Imaging , vol.17 , Issue.8 , pp. 1211-1218
    • Helms, G.1
  • 28
    • 0037329368 scopus 로고    scopus 로고
    • Review of lamotrigine and its clinical applications in epilepsy
    • Choi H, Morrell MJ. Review of lamotrigine and its clinical applications in epilepsy. Expert Opin Pharmacother 2003;4(2):243-51.
    • (2003) Expert Opin Pharmacother , vol.4 , Issue.2 , pp. 243-251
    • Choi, H.1    Morrell, M.J.2
  • 30
    • 0036714730 scopus 로고    scopus 로고
    • Valproate-induced encephalopathy: Assessment with MR imaging and 1H MR spectroscopy
    • Ziyeh S, Thiel T, Spreer J, et al. Valproate-induced encephalopathy: assessment with MR imaging and 1H MR spectroscopy. Epilepsia 2002;43(9):1101-5.
    • (2002) Epilepsia , vol.43 , Issue.9 , pp. 1101-1105
    • Ziyeh, S.1    Thiel, T.2    Spreer, J.3
  • 31
    • 0042352201 scopus 로고    scopus 로고
    • A proton magnetic resonance spectroscopy study of metabolites in the occipital lobes in epilepsy
    • Simister RJ, McLean MA, Barker GJ, et al. A proton magnetic resonance spectroscopy study of metabolites in the occipital lobes in epilepsy. Epilepsia 2003;44(4):550-8.
    • (2003) Epilepsia , vol.44 , Issue.4 , pp. 550-558
    • Simister, R.J.1    McLean, M.A.2    Barker, G.J.3
  • 32
    • 0037461312 scopus 로고    scopus 로고
    • MRI volumetry of the thalamus in temporal, extratemporal, and idiopathic generalized epilepsy
    • Natsume J, Bernasconi N, Andermann F, et al. MRI volumetry of the thalamus in temporal, extratemporal, and idiopathic generalized epilepsy. Neurology 2003;60(8):1296-300.
    • (2003) Neurology , vol.60 , Issue.8 , pp. 1296-1300
    • Natsume, J.1    Bernasconi, N.2    Andermann, F.3
  • 33
    • 0031016206 scopus 로고    scopus 로고
    • Glutamate and aspartate immunoreactivity in the reciprocal projections between the anterior thalamic nuclei and the retrosplenial granular cortex in the rat
    • Gonzalo-Ruiz A, Sanz JM, Morte L, et al. Glutamate and aspartate immunoreactivity in the reciprocal projections between the anterior thalamic nuclei and the retrosplenial granular cortex in the rat. Brain Res Bull 1997;42(4):309-21.
    • (1997) Brain Res Bull , vol.42 , Issue.4 , pp. 309-321
    • Gonzalo-Ruiz, A.1    Sanz, J.M.2    Morte, L.3
  • 34
    • 0033848981 scopus 로고    scopus 로고
    • In vivo measurements of glutamine+glutamate (Glx) and N-acetyl aspartate (NAA) levels in human partial epilepsy
    • Savic I, Thomas AM, Ke Y, et al. In vivo measurements of glutamine+glutamate (Glx) and N-acetyl aspartate (NAA) levels in human partial epilepsy. Acta Neurol Scand 2000;102(3):179-88.
    • (2000) Acta Neurol Scand , vol.102 , Issue.3 , pp. 179-188
    • Savic, I.1    Thomas, A.M.2    Ke, Y.3
  • 35
    • 0038729271 scopus 로고    scopus 로고
    • Metabolic changes after repetitive transcranial magnetic stimulation (rTMS) of the left prefrontal cortex: A sham-controlled proton magnetic resonance spectroscopy (1H MRS) study of healthy brain
    • Michael N, Gosling M, Reutemann M, et al. Metabolic changes after repetitive transcranial magnetic stimulation (rTMS) of the left prefrontal cortex: a sham-controlled proton magnetic resonance spectroscopy (1H MRS) study of healthy brain. Eur J Neurosci 2003;17(11):2462-8.
    • (2003) Eur J Neurosci , vol.17 , Issue.11 , pp. 2462-2468
    • Michael, N.1    Gosling, M.2    Reutemann, M.3
  • 36
    • 0027262604 scopus 로고
    • Extracellular hippocampal glutamate and spontaneous seizure in the conscious human brain
    • During MJ, Spencer DD. Extracellular hippocampal glutamate and spontaneous seizure in the conscious human brain. Lancet 1993;341(8861):1607-10.
    • (1993) Lancet , vol.341 , Issue.8861 , pp. 1607-1610
    • During, M.J.1    Spencer, D.D.2
  • 37
    • 0035179010 scopus 로고    scopus 로고
    • In vivo detection of postictal perturbations of cerebral metabolism by use of proton MR spectroscopy: Preliminary results in a canine model of prolonged generalized seizures
    • Neppl R, Nguyen CM, Bowen W, et al. In vivo detection of postictal perturbations of cerebral metabolism by use of proton MR spectroscopy: preliminary results in a canine model of prolonged generalized seizures. AJNR Am J Neuroradiol 2001;22(10):1933-43.
    • (2001) AJNR Am J Neuroradiol , vol.22 , Issue.10 , pp. 1933-1943
    • Neppl, R.1    Nguyen, C.M.2    Bowen, W.3
  • 38
    • 0036326330 scopus 로고    scopus 로고
    • Decreased expression of glutamate transporters in genetic absence epilepsy rats before seizure occurrence
    • Dutuit M, Touret M, Szymocha R, et al. Decreased expression of glutamate transporters in genetic absence epilepsy rats before seizure occurrence. J Neurochem 2002;80(6):1029-38.
    • (2002) J Neurochem , vol.80 , Issue.6 , pp. 1029-1038
    • Dutuit, M.1    Touret, M.2    Szymocha, R.3
  • 39
    • 0038754164 scopus 로고    scopus 로고
    • Functional magnetic resonance imaging of human absence seizures
    • Salek-Haddadi A, Lemieux L, Merschhemke M, et al. Functional magnetic resonance imaging of human absence seizures. Ann Neurol 2003;53(5):663-7.
    • (2003) Ann Neurol , vol.53 , Issue.5 , pp. 663-667
    • Salek-Haddadi, A.1    Lemieux, L.2    Merschhemke, M.3
  • 40
    • 2442605725 scopus 로고    scopus 로고
    • fMRI activation during spike and wave discharges in idiopathic generalized epilepsy
    • Aghakhani Y, Bagshaw AP, Benar CG, et al. fMRI activation during spike and wave discharges in idiopathic generalized epilepsy. Brain 2004;127(Pt 5):1127-44.
    • (2004) Brain , vol.127 , Issue.PART 5 , pp. 1127-1144
    • Aghakhani, Y.1    Bagshaw, A.P.2    Benar, C.G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.