Analysis of 1.5 Tesla proton mr spectra of human brain using LCModel and an imported basis set

Magnetic Resonance Imaging

Volumn 17, Issue 8, 1999, Pages 1211-1218

  Helms, Gunther ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Automation; Human brain; LCModel; Proton MRS; Quantitation

Indexed keywords

CHOLINE; GLUTAMINE;

ADULT; ARTICLE; ATTENUATION; AUTOMATION; BRAIN; GRAY MATTER; HUMAN; HUMAN EXPERIMENT; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SIGNAL NOISE RATIO; WHITE MATTER;

ADULT; ARTIFACTS; BRAIN; BRAIN CHEMISTRY; CALIBRATION; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; PARIETAL LOBE; PROTONS; REPRODUCIBILITY OF RESULTS;

ILEX COOKII;

EID: 0032877337     PISSN: 0730725X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0730-725X(99)00058-2     Document Type: Article

References (15)

1. Provencher S.W. Estimation of metabolite concentrations from localized in vivo proton NMR spectra. Magn. Reson. Med. 30:1993;672-679.
2. Webb P.G., Sailasuta N., Kohler S.J., Raidy T., Moats R.A., Hurd R.E. Automated single-voxel proton MRS. Technical development and multisite verification. Magn. Reson. Med. 31:1994;365-373.
3. Hennig J., Pfister H., Ernst T., Ott D. Direct absolute quantification of metabolites in the human brain with in vivo localized proton spectroscopy. NMR Biomed. 5:1992;193-199.
4. Kreis R., Ernst T., Ross B.D. Absolute quantification of water and metabolites in the human brain. II. Metabolite concentrations. J. Magn. Reson. B. 102:1993;9-19.
5. Cady E.B., D'Souza P.C. Analysis of proton brain spectra from human infants by fitting linear combinations of model spectra. J. Magn. Reson. Anal. 3:1997;5-14.
6. Pouwels P.J.W., Frahm J. Regional metabolite concentrations in human brain as determined by quantitative localized proton MRS. Magn. Reson. Med. 39:1998;53-60.
7. Frahm J., Merboldt K.D., Hänicke W. Localized proton spectroscopy using stimulated echoes. J. Magn. Reson. 72:1987;502-505.
8. Danielsen E.R., Henriksen O. Absolute quantitative proton NMR spectroscopy based on the amplitude of the local water suppression pulse. Quantification of brain water and metabolites. NMR Biomed. 7:1994;311-318.
9. Helms, G. Local sensitivity correction in quantitative localized MRS of the human brain. In: Book of Abstracts: Fifth Annual Meeting of the International Society of Magnetic Resonance in Medicine, Berkeley, CA: ISMRM; 1997: p. 1404.
10. Michaelis T., Merboldt K.D., Bruhn H., Hänicke W., Frahm J. Absolute concentrations of metabolites in the adult human brain in vivo Quantification of localized proton MR spectra . Radiology. 187:1993;219-227.
11. Klose U. In vivo proton spectroscopy in presence of eddy currents. Magn. Reson. Med. 14:1990;26-30.
12. Ernst T., Kreis R., Ross B.D. Absolute quantification of water and metabolites in the human brain. I. Compartments and water. J. Magn. Reson. B. 102:1993;1-8.
13. Hänicke, W.; Michaelis, T.; Pouwels, P.J.W.; Frahm, J.; Provencher, S.W. Improvements in the evaluation of in vivo proton MR spectra using a fully automated data analysis method (LCModel). In: Book of Abstracts: Third Annual Meeting of the Society of Magnetic Resonance, Berkeley, CA: SMR; 1995: p. 1953.
14. 1H MR Spectra In Vivo. Capabilities and limitations. In: Book of Abstracts: Third Annual Meeting of the Society of Magnetic Resonance, Berkeley, CA: SMR; 1995: p. 1952.
15. Michaelis T., Helms G., Frahm J. Metabolic alterations in brain autopsies Proton NMR identification of free glycerol . NMR Biomed. 9:1996;121-124.