Transcription factor ETS1 is critical for human uterine decidualization

Molecular Human Reproduction

Volumn 12, Issue 2, 2006, Pages 71-76

  Kessler, Cherie A ^a   Schroeder, Jennifer K ^a   Brar, Anoop K ^a   Handwerger, Stuart ^a  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

Decidualization; Differentiation; Gene expression; Pregnancy; Uterus

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; BUCLADESINE; CELL MARKER; DECORIN; ESTRADIOL; LAMININ; MEDROXYPROGESTERONE; MESSENGER RNA; PROLACTIN; PROSTAGLANDIN E2; SOMATOMEDIN BINDING PROTEIN 1; TISSUE INHIBITOR OF METALLOPROTEINASE 3; TRANSCRIPTION FACTOR ETS 1;

ARTICLE; CONTROLLED STUDY; DECIDUALIZATION; EXPERIMENTAL STUDY; EXPOSURE; FEMALE; FETUS; FIBROBLAST CULTURE; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; MARKER GENE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REGULATORY MECHANISM; UTERUS FUNCTION; WESTERN BLOTTING;

CELLS, CULTURED; DECIDUA; FEMALE; GENE EXPRESSION REGULATION; HUMANS; OLIGONUCLEOTIDES, ANTISENSE; PROTO-ONCOGENE PROTEIN C-ETS-1;

EID: 33645518228     PISSN: 13609947     EISSN: 14602407     Source Type: Journal    
DOI: 10.1093/molehr/gal008     Document Type: Article

References (30)

1. Bartel FO, Higuchi T and Spyropoulos DD (2000) Mouse models in the study of the Ets family of transcription factors. Oncogene 19,6443-6454.
2. Brar AK, Frank GR, Kessler CA, Cedars MI and Handwerger S (1997) Progesterone-dependent decidualization of the human endometrium is mediated by cAMP. Endocrine 6,301-307.
3. Brar AK, Handwerger S, Kessler CA and Aronow BJ (2001) Gene induction and categorical reprogramming during in vitro human endometrial fibroblast decidualization. Physiol Genomics 7,135-148.
4. Brar AK, Kessler CA and Handwerger S (2002) An Ets motif in the proximal decidual prolactin promoter is essential for basal gene expression. J Mol Endocrinol 29,99-112.
5. Dhulipal PD (1997) Ets oncogene family. Indian J Exp Biol 35,315-322.
6. Dittmer J (2003) The biology of the Ets1 proto-oncogene. Mol Cancer 2,29.
7. Fleischman LF, Holtzclaw L, Russell JT, Mavrothalassitis G and Fisher RJ (1995) Ets-1 in astrocytes: Expression and transmitter-evoked phosphorylation. Mol Cell Biol 15,925-931.
8. 2 enhances human endometrial stromal cell differentiation. Endocrinology 134,258-263.
9. Gellersen B and Brosens J (2003) Cyclic AMP and progesterone receptor cross-talk in human endometrium: A decidualizing affair. J Endocrinol 178,357-372.
10. Gellersen B, Kempf R and Telgmann R (1997) Human endometrial stromal cells express novel isoforms of the transcriptional modulator CREM and up-regulate ICER in the course of decidualization. Mol Endocrinol 11,97-113.
11. Greenland KJ, Jantke I, Jenatschke S, Bracken KE, Vinson C and Gellersen B (2000) The human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase gene promoter is controlled by Ets and activating protein-1 transcription factors and progesterone. Endocrinology 141,581-597.
12. Hsu T, Trojanowska M and Watson DK (2004) Ets proteins in biological control and cancer. J Cell Biochem 91,896-903.
13. Jayaraman G, Srinivas R, Duggan C, Ferreira E, Swaminathan S, Somasundaram K, Williams J, Hauser C, Kurkinen M, Dhar R et al. (1999) p300/cAMP-responsive element-binding protein interactions with ets-1 and ets-2 in the transcriptional activation of the human stromelysin promoter. J Biol Chem 274,17342-17352.
14. Johnson W and Jameson JL (2000) Role of Ets2 in cyclic AMP regulation of the human chorionic gonadotropin beta promoter. Mol Cell Endocrinol 165,17-24.
15. Kilpatrick LM, Kola I and Salamonsen LA (1999) Transcription factors Ets1, Ets2, and Elf1 exhibit differential localization in human endometrium across the menstrual cycle and alternate isoforms in cultured endometrial cells. Biol Reprod 61,120-126.
16. Kola I, Brookes S, Green AR, Garber R, Tymms M, Papas TS and Seth A (1993) The Ets1 transcription factor is widely expressed during murine embryo development and is associated with mesodermal cells involved in morphogenetic processes such as organ formation. Proc Natl Acad Sci USA 90,7588-7592.
17. Lelievre E, Lionneton F, Soncin F and Vandenbunder B (2001) The Ets family contains transcriptional activators and repressors involved in angiogenesis. Int J Biochem Cell Biol 33,391-407.
18. Logan SK, Garabedian MJ, Campbell CE and Werb Z (1996) Synergistic transcriptional activation of the tissue inhibitor of metalloproteinases-1 promoter via functional interaction of AP-1 and Ets-1 transcription factors. J Biol Chem 271,774-782.
19. Luton D, Sibony O, Oury JF, Blot P, Dieterlen-Lievre F and Pardanaud L (1997) The c-ets1 protooncogene is expressed in human trophoblast during the first trimester of pregnancy. Early Hum Dev 47,147-156.
20. Morcos PA (2000) Gene switching: Analyzing a broad range of mutations using steric block antisense oligonucleotides. Methods Enzymol 313,174-189.
21. Morcos PA (2001) Achieving efficient delivery of morpholino oligos in cultured cells. Genesis 30,94-102.
22. Naito S, Shimizu S, Maeda S, Wang J, Paul R and Fagin JA (1998) Ets-1 is an early response gene activated by ET-1 and PDGF-BB in vascular smooth muscle cells. Am J Physiol 274,C472-C480.
23. Pei H, Yordy JS, Leng Q, Zhao Q, Watson DK and Li R (2003) EAPII interacts with ETS1 and modulates its transcriptional function. Oncogene 22,2699-2709.
24. Pufall MA, Lee GM, Nelson ML, Kang HS, Velyvis A, Kay LE, McIntosh LP and Graves BJ (2005) Variable control of Ets-1 DNA binding by multiple phosphates in an unstructured region. Science 309,142-145.
25. Rabault B and Ghysdael J (1994) Calcium-induced phosphorylation of ETS1 inhibits its specific DNA binding activity. J Biol Chem 269,28143-28151.
26. Richards RG, Brar AK, Frank GR, Hartman SM and Jikihara H (1995) Fibroblast cells from term human decidua closely resemble endometrial stromal cells: Induction of prolactin and insulin-like growth factor binding protein-1 expression. Biol Reprod 52,609-615.
27. Sharrocks AD, Brown AL, Ling Y and Yates PR (1997) The ETS-domain transcription factor family. Int J Biochem Cell Biology 29,1371-1387.
28. Takai N, Ueda T, Nishida M, Nasu K and Miyakawa I (2004) The relationship between oncogene expression and clinical outcome in endometrial carcinoma. Curr Cancer Drug Targets 4,511-520.
29. Trojanowska M (2000) Ets factors and regulation of the extracellular matrix. Oncogene 19,6464-6471.
30. Wakiya K, Begue A, Stehelin D and Shibuya M (1996) A cAMP response element and an Ets motif are involved in the transcriptional regulation of flt-1 tyrosine kinase (vascular endothelial growth factor receptor 1) gene. J Biol Chem 271,30823-30828.