Human endometrial stromal cells express novel isoforms of the transcriptional modulator CREM and up-regulate ICER in the course of decidualization

Molecular Endocrinology

Volumn 11, Issue 1, 1997, Pages 97-113

  Gellersen, Birgit ^a   Kempf, Rita ^a   Telgmann, Ralph ^a  

^a UNIVERSITY OF HAMBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; PROLACTIN;

ALTERNATIVE RNA SPLICING; ARTICLE; CARBOXY TERMINAL SEQUENCE; DECIDUALIZATION; DNA BINDING; ENDOMETRIUM; EXON; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; OPEN READING FRAME; PHOSPHORYLATION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STOP CODON; STROMA CELL; TRANSCRIPTION INITIATION; TRANSLATION INITIATION;

EID: 0031024683     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/mend.11.1.9875     Document Type: Article

References (50)

1. Daly DC, Maslar IA, Riddick DH 1983 Prolactin production during in vitro decidualization of proliferative endometrium. Am J Obstet Gynecol 145:672-678
2. Zhu HH, Huang JR, Mazella J, Rosenberg M, Tseng L 1990 Differential effects of progestin and relaxin on the synthesis and secretion of immunoreactive prolactin in long term culture of human endometrial stromal cells. J Clin Endocrinol Metab 71:889-899
3. Irwin JC, Kirk D, King RJB, Quigley MM, Gwatkin RBL 1989 Hormonal regulation of human endometrial stromal cells in culture: an in vitro model for decidualization. Fertil Steril 52:761-768
4. Tabanelli S, Tang B, Gurpide E 1992 In vitro decidualization of human endometrial stromal cells. J Steroid Biochem Mol Biol 42:337-344
5. Fay TN, Grudzinskas JG 1991 Human endometrial peptides: a review of their potential role in implantation and placentation. Hum Reprod 6:1311-1326
6. Johannisson E 1991 Morphological and histochemical factors related to implantation. Baillieres Clin Obst Gynaecol 5:191-209
7. Rutanen EM, Koistinen R, Sjöberg J, Julkunen M, Wahlströhm T, Bohn H, Seppälä M 1986 Synthesis of placental protein 12 by human endometrium. Endocrinology 118:1067-1071
8. Chen G, Huang JR, Mazella J, Tseng L 1989 Long-term effects of progestin and RU 486 on prolactin production and synthesis in human endometrial stromal cells. Hum Reprod 4:355-358
9. 2 enhances human endometrial stromal cell differentiation. Endocrinology 134:258-263
10. Tang B, Gurpide E 1993 Direct effect of gonadotropins on decidualization of human endometrial stromal cells. J Steroid Biochem Mol Biol 47:115-121
11. Ferrari A, Petraglia F, Gurpide E 1995 Corticotropin releasing factor decidualizes human endometrial stromal cells in vitro. Interaction with progestin. J Steroid Biochem Mol Biol 54:251-255
12. Tang B, Guller S, Gurpide E 1993 Cyclic adenosine 3′,5′-monophosphate induces prolactin expression in stromal cells isolated from human proliferative endometrium. Endocrinology 133:2197-2203
13. Huang JR, Tseng L, Bischof P, Jänne OA 1987 Regulation of prolactin production by progestin, estrogen, and relaxin in human endometrial stromal cells. Endocrinology 121:2011-2017
14. Tseng L, Gao JG, Chen R, Zhu HH, Mazella J, Powell DR 1992 Effect of progestin, antiprogestin, and relaxin on the accumulation of prolactin and insulin-like growth factor-binding protein-1 messenger ribonucleic acid in human endometrial stromal cells. Biol Reprod 47:441-450
15. DiMattia GE, Gellersen B, Duckworth ML, Friesen HG 1990 Human prolactin gene expression. The use of an alternative noncoding exon in decidua and the IM-9-P3 lymphoblast cell line. J Biol Chem 265:16412-16421
16. Gellersen B, Kempf R, Telgmann R, DiMattia GE 1994 Nonpituitary human prolactin gene transcription is independent of Pit-1 and differentially controlled in lymphocytes and in endometrial stroma. Mol Endocrinol 8:356-373
17. Telgmann R, Maronde E, Taskén K, Gellersen B, Activated protein kinase A is required for differentiation-dependent transcription of the decidual prolactin gene in human endometrial stromal cells. Endocrinology, in press
18. Foulkes NS, Borrelli E, Sassone-Corsi P 1991 CREM gene: use of alternative DNA binding domains generates multiple antagonists of cAMP-induced transcription. Cell 64:739-749
19. Meyer TE, Habener JF 1993 Cyclic adenosine 3′,5′-monophosphate response element binding protein (CREB) and related transcription-activating deoxyribonucleic acid-binding proteins. Endocr Rev 14:269-290
20. de Groot RP, Sassone-Corsi P 1993 Hormonal control of gene expression: multiplicity and versatility of cyclic adenosine 3′,5′-monophosphate-responsive nuclear regulators. Mol Endocrinol 7:145-153
21. Walker WH, Sanborn BM, Habener JF 1994 An isoform of transcription factor CREM expressed during spermatogenesis lacks the phosphorylation domain and represses cAMP-induced transcription. Proc Natl Acad Sci USA 91:12423-12427
22. Laoide BM, Foulkes NS, Schlotter F, Sassone-Corsi P 1993 The functional versatility of CREM is determined by its modular structure. EMBO J 12:1179-1191
23. Meyer TE, Habener JF 1992 Cyclic AMP response element binding protein CREB and modulator protein CREM are products of distinct genes. Nucleic Acids Res 20:6106
24. Foulkes NS, Mellstrom B, Benusiglio E, Sassone-Corsi P 1992 Developmental switch of CREM function during spermatogenesis: from antagonist to activator. Nature 355:80-84
25. Delmas V, Laoide BM, Masquilier D, de Groot RP, Fouldes NS, Sassone-Corsi P 1992 Alternative usage of initiation codons in mRNA encoding the cAMP-responsive element modulator generates regulators with opposite functions. Proc Natl Acad Sci USA
26. Stehle JH, Fouldes NS, Molina CA, Simonneaux V, Pévet P, Sassone-Corsi P 1993 Adrenergic signals direct rhythmic expression of transcriptional repressor CREM in the pineal gland. Nature 365:314-320
27. Molina CA, Fouldes NS, Lalli E, Sassone-Corsi P 1993 Inducibility and negative autoregulation of CREM: an alternative promoter directs the expression of ICER, an early response repressor. Cell 75:875-886
28. Hoeffler JP, Meyer TE, Waeber G, Habener JF 1990 Multiple adenosine 3′,5′-monophosphate response element DNA-binding proteins generated by gene diversification and alternative exon splicing. Mol Endocrinol 4:920-930
29. Ruppert S, Cole TJ, Boshart M, Schmid E, Schütz G 1992 Multiple mRNA isoforms of the transcription activator protein CREB: generation by alternative splicing and specific expression in primary spermatocytes. EMBO J 11:1503-1512
30. Gellersen B, Kempf R, Telgmann R, DiMattia GE 1995 Pituitary-type transcription of the human prolactin gene in the absence of Pit-1. Mol Endocrinol 9:887-901
31. Kozak M 1989 The scanning model for translation: an update. J Cell Biol 108:229-241
32. Hoeffler MP, Meyer TE, Yungdae Y, Jameson JL, Habener JF 1988 Cyclic AMP-responsive DNA-binding protein: structure based on a cloned placental cDNA. Science 242:1430-1433
33. Yamamoto KK, Gonzalez GA, Briggs IWH, Montminy MR 1988 Phosphorylation-induced binding and transcriptional efficacy of nuclear factor CREB. Nature 334:494-498
34. Chrivia JC, Kwok RPS, Lamb N, Hagiwara M, Montminy MR, Goodman RH 1993 Phosphorylated CREB binds specifically to the nuclear protein CBP. Nature 365: 855-859
35. Lamas M, Monaco L, Zazopoulos E, Lalli E, Tamai K, Penna L, Mazzucchelli C, Nantel F, Foulkes NS, Sassone-Corsi P 1996 CREM: a master-switch in the transcriptional response to cAMP. Philos Trans R Soc Lond [Biol] 351:561-567
36. Waeber G, Meyer TE, LeSieur M, Hermann HL, Gérard N, Habener JF 1991 Developmental stage-specific expression of cyclic adenosine 3′,5′-monophosphate response element binding protein CREB during spermatogenesis involves alternative exon splicing. Mol Endocrinol 5:1418-1430
37. Waeber G, Habener JF 1992 Novel testis germ cell-specific transcript of the CREB gene contains an alternatively spliced exon with multiple in-frame stop codons. Endocrinology 131:2010-2015
38. Girardet C, Walker WH, Habener JF 1996 An alternatively spliced polycistronic mRNA encoding cyclic adenosine 3′,5′-monophosphate (cAMP)-responsive transcription factor CREB (cAMP response element binding protein) in human testis extinguishes expression of an internally translated inhibitor CREB isoform. Mol Endocrinol 10:879-891
39. Walker WH, Girardet C, Habener JF 1996 Alternative exon splicing controls a translational switch from activator to repressor isoforms of transcription factor CREB during spermatogenesis. J Biol Chem 271:20145-20150
40. Waeber G, Habener J 1991 Nuclear translocation and DNA recognition signals colocalized within the bZIP domain of cyclic adenosine 3′,5′-monophosphate response element-binding protein. Mol Endocrinol 5:1431-1438
41. Masquilier D, Foulkes NS, Mattei M-G, Sassone-Corsi P 1993 Human CREM gene: evolutionary conservation, chromosomal localization, and inducibility of the transcript. Cell Growth Differ 4:931-937
42. Day RN, Walder JA, Maurer RA 1989 A protein kinase inhibitor gene reduces both basal and multihormone-stimulated prolactin gene transcription. J Biol Chem 264:431-436
43. Fei DTW, Gross MC, Lofgren JL, Mora-Worms M, Chen AB 1990 Cyclic AMP response to recombinant human relaxin by cultured human endometrial cells - a specific and high throughput in vitro bioassay. Biochem Biophys Res Commun 170:214-222
44. Bodor J, Spetz AL, Strominger JL, Habener JF 1996 cAMP inducibility of transcriptional repressor ICER in developing and mature human T lymphocytes. Proc Natl Acad Sci USA 93:3536-3541
45. Fujimoto T, Fujisawa J, Yoshida M 1994 Novel isoforms of human cyclic AMP-responsive element modulator (hCREM) mRNA. J Biochem 115:298-303
46. Cooke NE, Coit D, Shine J, Baxter JD, Martial JA 1981 Human prolactin: cDNA structural analysis and evolutionary comparisons. J Biol Chem 256:4007-4016
47. Knappik A, Plückthun A 1994 An improved affinity tag based on the FLAG peptide for the detection and purification of recombinant antibody fragments. Biotechniques 17:754-761
48. Maurer RA 1989 Both isoforms of the cAMP-dependent protein kinase catalytic subunit can activate transcription of the prolactin gene. J Biol Chem 264:6870-6873
49. Lin C, Lin SC, Chang CP, Rosenfeld MG 1992 Pit-1-dependent expression of the receptor for growth hormone releasing factor mediates pituitary cell growth. Nature 360:765-768
50. Rittenhouse J, Marcus F 1983 Peptide mapping by polyacrylamide gel electrophoresis after cleavage at aspartylprolyl peptide bonds in sodium dodecyl sulfate-containing buffers. Anal Biochem 138:442-448