An Ets motif in the proximal decidual prolactin promoter is essential for basal gene expression

Journal of Molecular Endocrinology

Volumn 29, Issue 1, 2002, Pages 99-112

  Brar, A K ^a   Kessler, C A ^a   Handwerger, S ^a  

^a UNIVERSITY OF CINCINNATI   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MUTANT PROTEIN; PROLACTIN; TRANSCRIPTION FACTOR ETS 1; BUCLADESINE; DNA; ESTRADIOL; ETS1 PROTEIN, HUMAN; MEDROXYPROGESTERONE ACETATE; ONCOPROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR ETS;

ARTICLE; CARCINOMA CELL; CELL STRAIN; CONTROLLED STUDY; DECIDUA; DECIDUALIZATION; ELECTROPHORETIC MOBILITY; ENDOMETRIUM CELL; FEMALE; GENE EXPRESSION; GENE MUTATION; GENE OVEREXPRESSION; GENE REPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN MOTIF; STROMA CELL; CELL CULTURE; CHEMISTRY; CYTOLOGY; DRUG EFFECT; ENDOMETRIUM; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; WESTERN BLOTTING;

BASE SEQUENCE; BLOTTING, WESTERN; BUCLADESINE; CELLS, CULTURED; DNA; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ENDOMETRIUM; ESTRADIOL; FEMALE; GENE EXPRESSION REGULATION; HUMAN; MEDROXYPROGESTERONE 17-ACETATE; MOLECULAR SEQUENCE DATA; PROLACTIN; PROMOTER REGIONS (GENETICS); PROTO-ONCOGENE PROTEINS; SUPPORT, U.S. GOV'T, P.H.S.; TRANSCRIPTION FACTORS; HUMANS; PROTO-ONCOGENE PROTEIN C-ETS-1; PROTO-ONCOGENE PROTEINS C-ETS;

EID: 0036668572     PISSN: 09525041     EISSN: None     Source Type: Journal    
DOI: 10.1677/jme.0.0290099     Document Type: Article

References (46)

1. Characterization of an upstream promoter directing extrapituitary expression of the human prolactin gene
2. Regulation of the human interleukin-5 promoter by Ets transcription factors. Ets1 and Ets-2, but not Elf-1, cooperate with GATA3 and HTLV-I Tax1
3. The lung-specific surfactant protein B gene promoter is a target for thyroid transcription factor 1 and hepatocyte nuclear factor 3, indicating common factors for organ-specific gene expression along the fore-gut axis
4. Functional interaction of c-Ets-1 and GHF-1/Pit-1 mediates Ras activation of pituitary-specific gene expression: Mapping of the essential c-Ets-1 domain
5. Interaction of Ets-1 and the POU-homeodomain protein GHF-1/Pit-1 reconstitutes pituitary-specific gene expression
6. The Pit-1 homeodomain and beta-domain interact with Ets-1 and modulate synergistic activation of the rat prolactin promoter
7. Laminin decreases PRL and IGFBP-1 expression during in vitro decidualization of human endometrial stromal cells
8. N5 endometrial stromal cell line: A model system to study decidual prolactin gene expression
9. Human endometrial fibroblasts immortalized by simian virus 40 large T antigen differentiate in response to a decidualization stimulus
10. Erg, an Ets-family member, differentially regulates human collagenase1 (MMP1) and stromelysin1 (MMP3) gene expression by physically interacting with the Fos/Jun complex
11. Role of distinct mitogen-activated protein kinase pathways and cooperation between Ets-2, ATF-2, and Jun family members in human urokinase-type plasminogen activator gene induction by interleukin-1 and tetradecanoyl phorbol acetate
12. The Ets family of proteins: Weak modulators of gene expression in quest for transcriptional partners
13. Human prolactin gene expression. The use of an alternative noncoding exon in decidua and the IM-9-lymphoblast cell line
14. 2 enhances human endometrial stromal cell differentiation
15. Prolactin (PRL) mRNA from human decidua differs from pituitary PRL mRNA but resembles the IM-9-P3 lymphoblast PRL transcript
16. Nonpituitary human prolactin gene transcription is independent of Pit-1 and differentially controlled in lymphocytes and in endometrial stroma
17. r 54 000 cytoplasmic protein
18. Involvement of the proto-oncogene c-ets 1 and the urokinase plasminogen activator during mouse implantation and placentation
19. Human uteroplacental lactogens: Physiology and molecular biology
20. A placenta-specific 5′ non-coding exon of human prolactin
21. A composite Ets/Pit-1 binding site in the prolactin gene can mediate transcriptional responses to multiple signal transduction pathways
22. Hormonal regulation of human endometrial stromal cells in culture: An in vitro model for decidualization
23. p300/cAMP-responsive element-binding protein interactions with ets-1 and ets-2 in the transcriptional activation of the human stromelysin promoter
24. Transcription of the lung-specific surfactant protein C gene is mediated by thyroid transcription factor 1
25. Transcription factors Ets-1, Ets-2, and Elf1 exhibit differential localization in human endometrium across the menstrual cycle and alternate isoforms in cultured endometrial cells
26. Regulation of Ets function by protein-protein interactions
27. Synergistic transcriptional activation of the tissue inhibitor of metalloproteinases-1 promoter via functional interaction of AP-1 and Ets-1 transcription factors
28. Rapid phosphorylation of Ets-2 accompanies mitogen-activated protein kinase activation and the induction of heparin-binding epidermal growth factor gene expression by oncogenic Raf-1
29. Ets-1 positively regulates expression of urokinase-type plasminogen activator (uPA) and invasiveness of astrocytic tumors
30. ERM, a PEA3 subfamily of Ets transcription factors, can cooperate with c-Jun
31. CCAAT/enhancer-binding proteins are mediators in the protein kinase A-dependent activation of the decidual prolactin promoter
32. Human dermal fibroblast cells express prolactin in vitro
33. Fibroblast cells from term human decidua closely resemble endometrial stromal cells: Induction of prolactin and insulin-like growth factor binding protein-1 expression
34. Pituitary Ets-1 and GABP bind to the growth factor regulatory sites of the rat prolactin promoter
35. The ETS-domain transcription factor family
36. Ets transcription factors cooperate with Sp1 to activate the human tenascin-C promoter
37. Identification of a placental-specific enhancer in the rat placental lactogen II gene that contains binding sites for members of the Ets and AP-1 (activator protein 1) families of transcription factors
38. In vitro decidualization of human endometrial stromal cells
39. Expression of c-Ets1 is associated with malignant potential in endometrial carcinoma
40. Ets factors and regulation of the extracellular matrix
41. The c-ets proto-oncogenes encode transcription factors that cooperate with c-Fos and c-Jun for transcriptional activation
42. Identification of a decidua-specific enhancer on the human prolactin gene with two critical activator protein 1 (AP-1) binding sites
43. Mammalian ets-1 and ets-2 genes encode highly conserved proteins
44. Identification of nucleotide preferences in DNA sequences recognised specifically by c-Ets-1 protein
45. Ras-mediated phosphorylation of a conserved threonine residue enhances the transactivation activities of c-Ets-1 and c-Ets-2