In silico human and rat Vss quantitative structure-activity relationship models

Journal of Medicinal Chemistry

Volumn 49, Issue 6, 2006, Pages 1953-1963

  Gleeson, M Paul ^a,b   Waters, Nigel J ^a   Paine, Stuart W ^a   Davis, Andrew M ^a  

^a ASTRAZENECA   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACEBUTOLOL; ACICLOVIR; ALPRAZOLAM; AMFEBUTAMONE; AMILORIDE; AMIODARONE; AMITRIPTYLINE; AMOXICILLIN; AMPICILLIN; ATROPINE; AURANOFIN; AZITHROMYCIN; BEPRIDIL; BISOPROLOL; BROMOCRIPTINE; CAFFEINE; CAPTOPRIL; CARBAMAZEPINE; CARBENICILLIN; CEFACLOR; CEFALEXIN; CEFPROZIL; CHLORAMBUCIL; CHLORAMPHENICOL; CHLOROTHIAZIDE; CHLORPHENIRAMINE MALEATE; CHLORPROPAMIDE; CHLORTALIDONE; CIMETIDINE; UNINDEXED DRUG;

ALLOMETRY; ANALYTIC METHOD; ARTICLE; ARTIFICIAL NEURAL NETWORK; BAYES THEOREM; DRUG DISTRIBUTION; HUMAN; MODEL; NONHUMAN; PREDICTION; QUANTITATIVE STRUCTURE ACTIVITY RELATION; STEADY STATE; SYNTHESIS;

ANIMALS; BAYES THEOREM; DATABASES, FACTUAL; DRUG DESIGN; HUMANS; MODELS, BIOLOGICAL; NEURAL NETWORKS (COMPUTER); PHARMACEUTICAL PREPARATIONS; PHARMACOKINETICS; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; RATS; REGRESSION ANALYSIS;

EID: 33645404135     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0510070     Document Type: Article

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