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Volumn 3, Issue SUPPL. 1, 2006, Pages 208-213

Treatment options of polycystic ovary syndrome in adolescence

Author keywords

Adolescence; Hirsutism; Hyperandrogenism; Insulin resistance; Menstrual irregularities; Obesity; PCOs; Treatment

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; ADIPONECTIN; ALDOSTERONE ANTAGONIST; ANDROGEN; ANTIANDROGEN; CYPROTERONE ACETATE; DESOGESTREL; ETHINYLESTRADIOL; FINASTERIDE; FLUTAMIDE; GLUCOSE; INSULIN; INSULIN SENSITIZING AGENT; METFORMIN; ORAL CONTRACEPTIVE AGENT; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; SPIRONOLACTONE; TROGLITAZONE;

EID: 33645402365     PISSN: 15654753     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper
Times cited : (4)

References (67)
  • 1
    • 0036034768 scopus 로고    scopus 로고
    • Adults polycystic ovary syndrome begins in childhood
    • Franks S. Adults polycystic ovary syndrome begins in childhood. Best Pract Res Clin Endocrinol Metab 2002;16:263-272
    • (2002) Best Pract Res Clin Endocrinol Metab , vol.16 , pp. 263-272
    • Franks, S.1
  • 2
    • 0032977329 scopus 로고    scopus 로고
    • Insulin action in the polycystic ovary syndrome
    • Dunaif A. Insulin action in the polycystic ovary syndrome. Endocrinol Metab Clin North Am 1999;28:341-359
    • (1999) Endocrinol Metab Clin North Am , vol.28 , pp. 341-359
    • Dunaif, A.1
  • 3
    • 0026699302 scopus 로고
    • Evidence for distinctive and intrinsic defects in insulin action in polycystic ovary syndrome
    • Dunaif A, Segal KR, Shelley DR, Green G, Dobrjiansky A, Licholai T. Evidence for distinctive and intrinsic defects in insulin action in polycystic ovary syndrome. Diabetes 1992;41:1257-1266
    • (1992) Diabetes , vol.41 , pp. 1257-1266
    • Dunaif, A.1    Segal, K.R.2    Shelley, D.R.3    Green, G.4    Dobrjiansky, A.5    Licholai, T.6
  • 4
    • 0018840897 scopus 로고
    • The polycystic ovary syndrome
    • Yen SS. The polycystic ovary syndrome. Clin Endocrinol 1980; 12:177-207
    • (1980) Clin Endocrinol , vol.12 , pp. 177-207
    • Yen, S.S.1
  • 5
    • 0032948363 scopus 로고    scopus 로고
    • Prevalence and predictors of risk for type 2 diabetes mellitus and impaired glucose tolerance in polycystic ovary syndrome: A prospective, controlled study in 254 affected women
    • Legro RS, Kunseiman AR, Dodson WC, Dunaif A. Prevalence and predictors of risk for type 2 diabetes mellitus and impaired glucose tolerance in polycystic ovary syndrome: a prospective, controlled study in 254 affected women. J Clin Endocrinol Metab 1999;84:165-169
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 165-169
    • Legro, R.S.1    Kunseiman, A.R.2    Dodson, W.C.3    Dunaif, A.4
  • 8
    • 0023189131 scopus 로고
    • Characterization of groups of hyperandrogenemic women with acanthosis nigricans, impaired glucose tolerance, and/or hyperinsulinemia
    • Dunaif A, Graf M, Mandeli J, Laumas V, Dobrjiansky A. Characterization of groups of hyperandrogenemic women with acanthosis nigricans, impaired glucose tolerance, and/or hyperinsulinemia. J Clin Endorinol Metab 1987;65:499-507
    • (1987) J Clin Endorinol Metab , vol.65 , pp. 499-507
    • Dunaif, A.1    Graf, M.2    Mandeli, J.3    Laumas, V.4    Dobrjiansky, A.5
  • 10
    • 0031456016 scopus 로고    scopus 로고
    • Insulin resistance and the polycystic ovary syndrome: Mechanisms and implications for pathogenesis
    • Dunaif A. Insulin resistance and the polycystic ovary syndrome: Mechanisms and implications for pathogenesis. Endocr Rev 1997; 18:774-800
    • (1997) Endocr Rev , vol.18 , pp. 774-800
    • Dunaif, A.1
  • 11
    • 0031790832 scopus 로고    scopus 로고
    • Insulin stimulates testosterone biosynthesis by human thecal cells from women with polycystic ovary syndrome by activating its own receptor and using inositolglycan mediators as the signal transduction system
    • Nestler JE, Jakubwicz DJ, De Vargas AF, Brik C, Quintero N, and Medina F. Insulin stimulates testosterone biosynthesis by human thecal cells from women with polycystic ovary syndrome by activating its own receptor and using inositolglycan mediators as the signal transduction system. J Clin Endorinol Metab 1998;83:2001-2005
    • (1998) J Clin Endorinol Metab , vol.83 , pp. 2001-2005
    • Nestler, J.E.1    Jakubwicz, D.J.2    De Vargas, A.F.3    Brik, C.4    Quintero, N.5    Medina, F.6
  • 12
    • 0028823250 scopus 로고
    • Insulin action in human granulose cells from normal and polycystic ovaries is mediated by the insulin receptor and not the type-1 insulin-like growth factor receptor
    • Willis D, Franks S. Insulin action in human granulose cells from normal and polycystic ovaries is mediated by the insulin receptor and not the type-1 insulin-like growth factor receptor. J Clin Endorinol Metab 1995;80:3788-3790
    • (1995) J Clin Endorinol Metab , vol.80 , pp. 3788-3790
    • Willis, D.1    Franks, S.2
  • 15
    • 0029798428 scopus 로고    scopus 로고
    • Ovarian 17-hydroxyprogesterone hyperresponsiveness to gonadotropin-releasing hormone (GnRH) agonist challenge in women with polycystic ovary syndrome is not mediated by luteinizing hormone hypersecretion: Evidence from GnRH agonist and human chorionic gonadotropin stimulation testing
    • Ibanez L, Hall JE, Potau N, Carrascosa A, Prat N, Taylor AE. Ovarian 17-hydroxyprogesterone hyperresponsiveness to gonadotropin-releasing hormone (GnRH) agonist challenge in women with polycystic ovary syndrome is not mediated by luteinizing hormone hypersecretion: evidence from GnRH agonist and human chorionic gonadotropin stimulation testing. J Clin Endocrinol Metab 1996;81:4103-4107
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 4103-4107
    • Ibanez, L.1    Hall, J.E.2    Potau, N.3    Carrascosa, A.4    Prat, N.5    Taylor, A.E.6
  • 16
    • 0030832255 scopus 로고    scopus 로고
    • Evidence for a primary abnormality of thecal cell steroidogenesis in the polycystic ovary syndrome
    • Gilling-Smith C, Story H, Rogers V and Franks S. Evidence for a primary abnormality of thecal cell steroidogenesis in the polycystic ovary syndrome. Clin Endocrinology 1997;47:93-99
    • (1997) Clin Endocrinology , vol.47 , pp. 93-99
    • Gilling-Smith, C.1    Story, H.2    Rogers, V.3    Franks, S.4
  • 18
    • 0033587746 scopus 로고    scopus 로고
    • Thirty - Seven candidate genes for polycystic ovary syndrome: Strongest evidence for linkage is with Follistatin
    • Urbanek M. Thirty - seven candidate genes for polycystic ovary syndrome: strongest evidence for linkage is with Follistatin. Proc. Natl. Acad. Sci. USA 1999:96,8573-8578
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 8573-8578
    • Urbanek, M.1
  • 20
    • 0028830625 scopus 로고
    • Decreased insulin sensitivity in prepubertal girls with premature adrenarche and acanthosis nigricans
    • Oppenheimer E, Linder B, Dimartino-Nardi J. Decreased insulin sensitivity in prepubertal girls with premature adrenarche and acanthosis nigricans. J Clin Endocrinol Metab 1995;80:614-618
    • (1995) J Clin Endocrinol Metab , vol.80 , pp. 614-618
    • Oppenheimer, E.1    Linder, B.2    Dimartino-Nardi, J.3
  • 22
    • 0033663503 scopus 로고    scopus 로고
    • Diagnosis of the polycystic ovary syndrome in adolescence: Comparison of adolescent and adult hyperandrogenism
    • Rosenfield RL, Ghai K, Ehrmann DA and Barnes RB. Diagnosis of the polycystic ovary syndrome in adolescence: comparison of adolescent and adult hyperandrogenism. J Pediatr Endocrinol Metab 13 Suppl 2000;5:1285-1289
    • (2000) J Pediatr Endocrinol Metab 13 Suppl , vol.5 , pp. 1285-1289
    • Rosenfield, R.L.1    Ghai, K.2    Ehrmann, D.A.3    Barnes, R.B.4
  • 23
    • 0033952196 scopus 로고    scopus 로고
    • Disorders of excessive hair growth in the adolescent
    • Plouffe Jr L. Disorders of excessive hair growth in the adolescent. Obstet Gynecol Clin North Am 2000;27:779-799
    • (2000) Obstet Gynecol Clin North Am , vol.27 , pp. 779-799
    • Plouffe Jr., L.1
  • 24
    • 2442608706 scopus 로고    scopus 로고
    • Debate: Polycystic ovary syndrome in adolescence - A therapeutic conundrum
    • Homburg R, Lambalk CB. Debate: Polycystic ovary syndrome in adolescence-a therapeutic conundrum. Hum Reprod 2004;19:1039-1042
    • (2004) Hum Reprod , vol.19 , pp. 1039-1042
    • Homburg, R.1    Lambalk, C.B.2
  • 25
    • 17444394871 scopus 로고    scopus 로고
    • Pfeifer, MD Polycystic ovary syndrome in adolescent girls
    • Samantha M. Pfeifer, MD Polycystic ovary syndrome in adolescent girls. Seminars in Pediatric Surgery 2005;14:111-117
    • (2005) Seminars in Pediatric Surgery , vol.14 , pp. 111-117
    • Samantha, M.1
  • 26
    • 0037588442 scopus 로고    scopus 로고
    • Treatment of the adolescent patient with polycystic ovary syndrome
    • Pfeifer SM, Dayal M. Treatment of the adolescent patient with polycystic ovary syndrome. Obstet Gynecol Clin N Am 2003;30:337-352
    • (2003) Obstet Gynecol Clin N Am , vol.30 , pp. 337-352
    • Pfeifer, S.M.1    Dayal, M.2
  • 27
    • 0032948363 scopus 로고    scopus 로고
    • Prevalence and predictors of risk for type 2 diabetes mellitus and impaired glucose tolerance in polycystic ovary syndrome: A prospective, controlled study in 254 affected women
    • Legro RS, Kunslman AR, Dodson WC, Dunaif A. Prevalence and predictors of risk for type 2 diabetes mellitus and impaired glucose tolerance in polycystic ovary syndrome: a prospective, controlled study in 254 affected women. J. Clin. Endocrinol. Metab 1999;84:165-169
    • (1999) J. Clin. Endocrinol. Metab , vol.84 , pp. 165-169
    • Legro, R.S.1    Kunslman, A.R.2    Dodson, W.C.3    Dunaif, A.4
  • 28
    • 0036481466 scopus 로고    scopus 로고
    • Polycystic ovary syndrome in adolescents
    • Kent SC and Legro RS. Polycystic ovary syndrome in adolescents. Adolesc Med 2002;13:73-88
    • (2002) Adolesc Med , vol.13 , pp. 73-88
    • Kent, S.C.1    Legro, R.S.2
  • 30
    • 0024442524 scopus 로고
    • The treatment of hyperandrogenism with oral contraceptives
    • Azziz R, Gay F. The treatment of hyperandrogenism with oral contraceptives. Semin Reprod Endocrinol 1989;7:246-254
    • (1989) Semin Reprod Endocrinol , vol.7 , pp. 246-254
    • Azziz, R.1    Gay, F.2
  • 31
    • 0036253418 scopus 로고    scopus 로고
    • Androgen and lipid profiles in adolescents with polycystic ovary syndrome who were treated with two forms of combined oral contraceptives
    • Mastorakos G, Koliopoulos C, Creatsas G. Androgen and lipid profiles in adolescents with polycystic ovary syndrome who were treated with two forms of combined oral contraceptives. Fertility and Sterility 2002:77(5)919-927
    • (2002) Fertility and Sterility , vol.77 , Issue.5 , pp. 919-927
    • Mastorakos, G.1    Koliopoulos, C.2    Creatsas, G.3
  • 32
    • 0029160057 scopus 로고
    • Medical treatment of androgen-dependent hirsutism: Clinical review
    • Rittmaster RS. Medical treatment of androgen-dependent hirsutism: clinical review. J Clin Endocrinol Metab 1995;80:2559-2563
    • (1995) J Clin Endocrinol Metab , vol.80 , pp. 2559-2563
    • Rittmaster, R.S.1
  • 33
    • 0013687331 scopus 로고
    • Evaluation and treatment of unresponsive hirsutism
    • Pittaway DE. Evaluation and treatment of unresponsive hirsutism. Sex Med Today 1985;3:14-18.
    • (1985) Sex Med Today , vol.3 , pp. 14-18
    • Pittaway, D.E.1
  • 34
    • 0029160057 scopus 로고
    • Medical treatment of androgen-dependent hirsutism: Clinical review
    • Rittmaster RS. Medical treatment of androgen-dependent hirsutism: clinical review. J Clin Endocrinol Metab 1995;80:2559-2563
    • (1995) J Clin Endocrinol Metab , vol.80 , pp. 2559-2563
    • Rittmaster, R.S.1
  • 35
    • 0020039720 scopus 로고
    • Treatment of hirsutism with spironolactone
    • Cumming DC, Yang JC, Rebar RW, Yen SS. Treatment of hirsutism with spironolactone. JAMA 1982;247:1295-1298
    • (1982) JAMA , vol.247 , pp. 1295-1298
    • Cumming, D.C.1    Yang, J.C.2    Rebar, R.W.3    Yen, S.S.4
  • 36
    • 0021909171 scopus 로고
    • The effects of two doses of spironolactone on serum androgens and anagen hair in hirsute women
    • Lobo RA, Shoupe D, Serafini P, Brinton D, Horton R. The effects of two doses of spironolactone on serum androgens and anagen hair in hirsute women. Fertil Steril 1985;43:200-205
    • (1985) Fertil Steril , vol.43 , pp. 200-205
    • Lobo, R.A.1    Shoupe, D.2    Serafini, P.3    Brinton, D.4    Horton, R.5
  • 37
    • 0029863959 scopus 로고    scopus 로고
    • The insulin resistance in women with hyperandrogenism is partially reversed by antiandrogen treatment: Evidence that androgens impair insulin action in women
    • Moghetti P, Tosi F, Castello, Magnani CM, Negri C, Brun E, Furlani L, Caputo M, Muggeo M. The insulin resistance in women with hyperandrogenism is partially reversed by antiandrogen treatment: evidence that androgens impair insulin action in women. J Clin Endocrinol Metab 1996;81:952-960
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 952-960
    • Moghetti, P.1    Tosi, F.2    Castello3    Magnani, C.M.4    Negri, C.5    Brun, E.6    Furlani, L.7    Caputo, M.8    Muggeo, M.9
  • 38
    • 0023831235 scopus 로고
    • Side-effects of spironolactone therapy in the hirsute woman
    • Helfer EL, Miller JL and Rose LI. Side-effects of spironolactone therapy in the hirsute woman. J Clin Endocrinol Metab 1988;66:208-211
    • (1988) J Clin Endocrinol Metab , vol.66 , pp. 208-211
    • Helfer, E.L.1    Miller, J.L.2    Rose, L.I.3
  • 39
    • 0023793128 scopus 로고
    • The pharmacokinetics of flutamide and its major metabolites after a single oral dose and during chronic treatment
    • Schultz M, Schmoldt A, Donn F and Becker H. The pharmacokinetics of flutamide and its major metabolites after a single oral dose and during chronic treatment. Eur J Pharmacol 1988;34:633-635
    • (1988) Eur J Pharmacol , vol.34 , pp. 633-635
    • Schultz, M.1    Schmoldt, A.2    Donn, F.3    Becker, H.4
  • 41
    • 0033694297 scopus 로고    scopus 로고
    • Treatment of hirsutism, hyperandrogenism, oligomenorrhea, dyslipidemia, and hyperinsulinism in nonobese, adolescent girls: Effects of flutamide
    • Ibanez L, Potau N, Marcos MV, de Degher F. Treatment of hirsutism, hyperandrogenism, oligomenorrhea, dyslipidemia, and hyperinsulinism in nonobese, adolescent girls: effects of flutamide. J Clin Endocrinol Metab 2000;85:3251-3255
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 3251-3255
    • Ibanez, L.1    Potau, N.2    Marcos, M.V.3    De Degher, F.4
  • 43
    • 0024160877 scopus 로고    scopus 로고
    • Banting lecture, 1988. Role of insulin resistance in human disease
    • Reaven GM. Banting lecture, 1988. Role of insulin resistance in human disease. Diabetes 37:1595-1607
    • Diabetes , vol.37 , pp. 1595-1607
    • Reaven, G.M.1
  • 44
    • 0025980368 scopus 로고
    • Insulin resistance, hyperinsulinemia, hypertriglyceridemia, and hypertension. Parallels between human disease and rodent models
    • Reaven GM. Insulin resistance, hyperinsulinemia, hypertriglyceridemia, and hypertension. Parallels between human disease and rodent models. Diabetes Care, 1991;14:195-202.
    • (1991) Diabetes Care , vol.14 , pp. 195-202
    • Reaven, G.M.1
  • 45
    • 0344286476 scopus 로고    scopus 로고
    • Prevalence of impaired glucose tolerance and diabetes in women with polycystic ovary syndrome
    • Ehrmann DA, Barnes RB, Rosenfield RL, Cavaghan MK, Imperial J. Prevalence of impaired glucose tolerance and diabetes in women with polycystic ovary syndrome. Diabetes Care 1999;22:141-146
    • (1999) Diabetes Care , vol.22 , pp. 141-146
    • Ehrmann, D.A.1    Barnes, R.B.2    Rosenfield, R.L.3    Cavaghan, M.K.4    Imperial, J.5
  • 47
    • 0142247208 scopus 로고    scopus 로고
    • Metformin in polycystic ovary syndrome: Systematic review and metaanalysis
    • Lord JM, Flight IM, Norman RJ. Metformin in polycystic ovary syndrome: systematic review and metaanalysis. BMJ 2003;327:951-953
    • (2003) BMJ , vol.327 , pp. 951-953
    • Lord, J.M.1    Flight, I.M.2    Norman, R.J.3
  • 49
    • 0346171340 scopus 로고    scopus 로고
    • Insulin sensitization early after menarche prevents progression from precocious pubarche to polycystic ovary syndrome
    • Ibanez L, Ferrer A, Ong K, Amin R, Dunger D, and de Zegher F. Insulin sensitization early after menarche prevents progression from precocious pubarche to polycystic ovary syndrome. J Pediatr 2004;144:23-29
    • (2004) J Pediatr , vol.144 , pp. 23-29
    • Ibanez, L.1    Ferrer, A.2    Ong, K.3    Amin, R.4    Dunger, D.5    De Zegher, F.6
  • 50
    • 0018777709 scopus 로고
    • Metformin in management of pregnant insulin-independent diabetics
    • Coetzee EJ, Jackson WPU. Metformin in management of pregnant insulin-independent diabetics. Diabetologia 1979;16:241-245
    • (1979) Diabetologia , vol.16 , pp. 241-245
    • Coetzee, E.J.1    Jackson, W.P.U.2
  • 51
  • 52
    • 0030751488 scopus 로고    scopus 로고
    • Thiazolidinedions: In current therapies for diabetes
    • Henry R. Thiazolidinedions: in current therapies for diabetes. Endocrinol. Metab. Clin. N Am 1997;26:553-573
    • (1997) Endocrinol. Metab. Clin. N Am , vol.26 , pp. 553-573
    • Henry, R.1
  • 53
    • 0029896904 scopus 로고    scopus 로고
    • Acute and chronic effects of troglitazone (CS-045) on isolated rat ventricular cardiomyocytes
    • Bahr M, Spelleken M, Bock M von Holtey M, Kiehn R, Eckel J. Acute and chronic effects of troglitazone (CS-045) on isolated rat ventricular cardiomyocytes. Diabetologia 1996;39:766-774
    • (1996) Diabetologia , vol.39 , pp. 766-774
    • Bahr, M.1    Spelleken, M.2    Bock, M.3    Von Holtey, M.4    Kiehn, R.5    Eckel, J.6
  • 56
    • 0028818522 scopus 로고
    • Metabolic effects of oral contraceptives in women with polycystic ovary syndrome
    • Korytkowski MT, Mokan M, Horwitz MJ, Berga SL. Metabolic effects of oral contraceptives in women with polycystic ovary syndrome. J Clin Endocrinol. Metab 1995;80:3327-3334
    • (1995) J Clin Endocrinol. Metab , vol.80 , pp. 3327-3334
    • Korytkowski, M.T.1    Mokan, M.2    Horwitz, M.J.3    Berga, S.L.4
  • 57
    • 0031789384 scopus 로고    scopus 로고
    • Effects of two antiandrogen treatments on hirsutism and insulin sensitivity in women with polycystic ovary syndrome
    • Dahlgren E, Landin K, Krotkiewski M, Holm G, Janson PO. Effects of two antiandrogen treatments on hirsutism and insulin sensitivity in women with polycystic ovary syndrome. Hum. Reprod 1998;13:2706-2711
    • (1998) Hum Reprod , vol.13 , pp. 2706-2711
    • Dahlgren, E.1    Landin, K.2    Krotkiewski, M.3    Holm, G.4    Janson, P.O.5
  • 61
    • 2942677215 scopus 로고    scopus 로고
    • Comparison of efficacy of spironolactone with metformin in the management of polycystic ovary syndrome: An open-labelled study
    • Ganie MA, Khurana ML, Eunice M, Gulati M, Dwivedi SN, Amniti AC. Comparison of efficacy of spironolactone with metformin in the management of polycystic ovary syndrome: an open-labelled study. J Clin. Endocrinol Metab 2004;89(6):2756-2762
    • (2004) J Clin. Endocrinol Metab , vol.89 , Issue.6 , pp. 2756-2762
    • Ganie, M.A.1    Khurana, M.L.2    Eunice, M.3    Gulati, M.4    Dwivedi, S.N.5    Amniti, A.C.6
  • 62
    • 0038644550 scopus 로고    scopus 로고
    • Low dose flutamide - Metformin therapy reverses insulin resistance and reduces fat mass in nonobese adolescents with ovarian hyperandrogenism
    • Ibanez L, Ong K, Ferrer A, Amin R, Dunger D, de Zegher F. Low dose flutamide - metformin therapy reverses insulin resistance and reduces fat mass in nonobese adolescents with ovarian hyperandrogenism. J. Clin. Endocrinol. Metab., 2003;88:2600-2606.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 2600-2606
    • Ibanez, L.1    Ong, K.2    Ferrer, A.3    Amin, R.4    Dunger, D.5    De Zegher, F.6
  • 63
    • 11144354560 scopus 로고    scopus 로고
    • Ethinylestradiol-Drospirone, Flutamide-Metformin, or both for adolescents and women with hyperinsulinemic hyperandrogenism:opposite effects on adipocytokines and body adiposity
    • Ibanez L, de Zegher F. Ethinylestradiol-Drospirone, Flutamide-Metformin, or both for adolescents and women with hyperinsulinemic hyperandrogenism: opposite effects on adipocytokines and body adiposity. J Clin Endocrinol Metab 2004;89:1592-1597
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 1592-1597
    • Ibanez, L.1    De Zegher, F.2
  • 64
    • 0025260903 scopus 로고    scopus 로고
    • Interleukin-6: An overview
    • Van Snick J. Interleukin-6: an overview. Annu. Rev. Immunol 1996;8:253-278
    • (1996) Annu Rev Immunol , vol.8 , pp. 253-278
    • Van Snick, J.1
  • 66
    • 0042384578 scopus 로고    scopus 로고
    • Glucose-to-insulin ratio rather than sex hormone-binding globulin and adiponectin levels is the best predictor of insulin resistance in nonobese women with polycystic ovary syndrome
    • Ducluzeau PH, Cousin P, Malvoisin E, Bornet H, Vidal H, Laville M, Pugeat AI. Glucose-to-insulin ratio rather than sex hormone-binding globulin and adiponectin levels is the best predictor of insulin resistance in nonobese women with polycystic ovary syndrome. J Clin Endocrinol. Metab 2003;88:3626-3631
    • (2003) J Clin Endocrinol. Metab , vol.88 , pp. 3626-3631
    • Ducluzeau, P.H.1    Cousin, P.2    Malvoisin, E.3    Bornet, H.4    Vidal, H.5    Laville, M.6    Pugeat, A.I.7
  • 67
    • 0042624707 scopus 로고    scopus 로고
    • Pioglitazone and metformin in obese women with polycystic ovary syndrome not optimally responsive to metformin
    • Glueck C, Moreira A, Goldenberg N, Sieve L and Wang P. Pioglitazone and metformin in obese women with polycystic ovary syndrome not optimally responsive to metformin. Hum Reprod 2003;18:1618-1625
    • (2003) Hum Reprod , vol.18 , pp. 1618-1625
    • Glueck, C.1    Moreira, A.2    Goldenberg, N.3    Sieve, L.4    Wang, P.5


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