Cytochrome P450 expression and metabolic activation of cooked food mutagen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in MCF10A breast epithelial cells

Chemico-Biological Interactions

Volumn 160, Issue 3, 2006, Pages 204-216

  Thomas, Ronald D ^a   Green, Mario R ^a   Wilson, Chantell ^a   Weckle, Amy L ^b   Duanmu, Zhengbo ^b   Kocarek, Thomas A ^b   Runge Morris, Melissa ^b  

^a FLORIDA A AND M UNIVERSITY   (United States)

^b WAYNE STATE UNIVERSITY   (United States)

Author keywords

Breast carcinogenesis; Cooked food mutagens; CYP; DNA adducts; Heterocyclic amines; Human breast epithelial cells; P450; PhIP

Indexed keywords

2 AMINO 1 METHYL 6 PHENYLIMIDAZO[4,5 B]PYRIDINE; 2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; CYTOCHROME P450; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; CYTOCHROME P450 1B1; CYTOCHROME P450 4B1; ETHOXYRESORUFIN DEETHYLASE; MESSENGER RNA;

ARTICLE; BREAST EPITHELIUM; CONTROLLED STUDY; COOKED FOOD; DNA ADDUCT; DNA DAMAGE; DRUG EFFECT; HUMAN; HUMAN CELL; METABOLIC ACTIVATION; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 33645397148     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2006.01.007     Document Type: Article

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