A new 4-nitrobenzyl carbonate prodrug of methyl 5-benzyl-2-hydroxy-11- methylene-6-oxo-5H-benzo[b]carbazole-1-carboxylate for potential use with nitroreductase-based gene-directed enzyme prodrug therapy (GDEPT)

Pharmazie

Volumn 61, Issue 3, 2006, Pages 244-245

  Asche, Christian ^a,c   Kucklaender, U ^b  

^a UNIVERSITÉ JOSEPH FOURIER   (France)

^b HEINRICH HEINE UNIVERSITY   (Germany)

^c UNIV GRENOBLE ALPES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

4 NITROBENZYL CARBONATE; 4 NITROBENZYLOXYCARBONYL; BACTERIAL ENZYME; CARBOXYLIC ACID DERIVATIVE; METHYL 5 BENZYL 2 HYDROXY 11 METHYLENE 6 OXO 5H BENZO[B]CARBAZOLE 1 CARBOXYLATE; NITROREDUCTASE; PRODRUG; UNCLASSIFIED DRUG;

ARTICLE; CANCER THERAPY; DRUG SYNTHESIS; ESCHERICHIA COLI; GENE DIRECTED ENZYME PRODRUG THERAPY; HUMAN; HUMAN CELL; IN VITRO STUDY; STRUCTURE ACTIVITY RELATION; TUMOR CELL LINE;

CARBAZOLES; CARBOXYLIC ACIDS; ENZYMES; ESCHERICHIA COLI; GENE THERAPY; NITROREDUCTASES; PRODRUGS;

EID: 33645339520     PISSN: 00317144     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (9)

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