Prevention of cytotoxic T lymphocyte responses to factor IX-expressing hepatocytes by gene transfer-induced regulatory T cells

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 12, 2006, Pages 4592-4597

  Dobrzynski, Eric ^a   Fitzgerald, Julie C ^a   Cao, Ou ^b   Mingozzi, Federico ^a   Wang, Lixin ^b   Herzog, Roland W ^b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF FLORIDA   (United States)

Author keywords

Adenoassociated virus; Gene therapy; Hemophilia; Tolerance

Indexed keywords

BLOOD CLOTTING FACTOR 9; CD8 ANTIGEN; GENE PRODUCT;

ADENOVIRUS VECTOR; ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLEEDING DISORDER; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXIC T LYMPHOCYTE; ENZYME LINKED IMMUNOSPOT ASSAY; FLOW CYTOMETRY; GENE THERAPY; GENE TRANSFER; GENETIC DISORDER; HEMOPHILIA; IMMUNOLOGICAL TOLERANCE; LYMPHOCYTE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPLEEN CELL;

ADENOVIRIDAE; ADOPTIVE TRANSFER; ANIMALS; CYTOTOXICITY, IMMUNOLOGIC; FACTOR IX; GENE THERAPY; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HEPATOCYTES; IMMUNE TOLERANCE; IMMUNOSUPPRESSION; MALE; MICE; MICE, INBRED STRAINS; T-LYMPHOCYTES, CYTOTOXIC; T-LYMPHOCYTES, REGULATORY;

ADENOVIRIDAE; ANIMALIA;

EID: 33645240071     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0508685103     Document Type: Article

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