A single lysyl residue defines the binding specificity of a human odorant-binding protein for aldehydes

FEBS Letters

Volumn 580, Issue 8, 2006, Pages 2102-2108

  Tcatchoff, Lionel ^a   Nespoulous, Claude ^a   Pernollet, Jean Claude ^a   Briand, Loïc ^a  

^a INRA   (France)

Author keywords

Lipocalin; Odorant binding protein; Olfaction; Olfactory mucus

Indexed keywords

ALDEHYDE; ALIPHATIC CARBOXYLIC ACID; BINDING PROTEIN; FLUORESCENT DYE; LYSINE; ODORANT BINDING PROTEIN; PALMITIC ACID; UNCLASSIFIED DRUG; UNDECANAL;

AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; FLUORESCENCE ANALYSIS; MOLECULAR MODEL; NUCLEOTIDE SEQUENCE; OLFACTORY RECEPTOR; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; SITE DIRECTED MUTAGENESIS;

1-NAPHTHYLAMINE; ALDEHYDES; AMINO ACID SEQUENCE; ANIMALS; CARRIER PROTEINS; DANSYL COMPOUNDS; FATTY ACIDS; FLUORESCENT DYES; HUMANS; LIGANDS; LYSINE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS; MUTATION; PALMITIC ACID; PROTEIN BINDING; RECOMBINANT PROTEINS; SEQUENCE HOMOLOGY; SUBSTRATE SPECIFICITY; TITRIMETRY;

EID: 33645221480     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2006.03.017     Document Type: Article

References (22)

1. P. Pelosi Perireceptor events in olfaction J. Neurobiol. 30 1996 3 19
2. L. Briand, C. Eloit, C. Nespoulous, V. Bezirard, J.C. Huet, C. Henry, F. Blon, D. Trotier, and J-C. Pernollet Evidence of an odorant-binding protein in the human olfactory mucus: location, structural characterization, and odorant-binding properties Biochemistry 41 2002 7241 7252
3. F. Vincent, S. Spinelli, R. Ramoni, S. Grolli, P. Pelosi, C. Cambillau, and M. Tegoni Complexes of porcine odorant binding protein with odorant molecules belonging to different chemical classes J. Mol. Biol. 300 2000 127 139
4. P. Pelosi The role of perireceptor events in vertebrate olfaction Cell. Mol. Life Sci. 58 2001 503 509
5. M. Tegoni, P. Pelosi, F. Vincent, S. Spinelli, V. Campanacci, S. Grolli, R. Ramoni, and C. Cambillau Mammalian odorant binding proteins Biochim. Biophys. Acta 1482 2000 229 240
6. D. Löbel, M. Jacob, M. Völkner, and H. Breer Odorants of different chemical classes interact with distinct odorant binding protein subtypes Chem. Senses 27 2002 39 44
7. P. Xu, R. Atkinson, D.N. Jones, and D.P. Smith Drosophila OBP LUSH is required for activity of pheromone-sensitive neurons Neuron 45 2005 193 200
8. M. Vogt, and A. Skerra Bacterially produced apolipoprotein D binds progesterone and arachidonic acid, but not bilirubin or E-3M2H J. Mol. Recognit. 1 2001 79 86
9. C. Nespoulous, L. Briand, M.M. Delage, V. Tran, and J.-C. Pernollet Odorant binding and conformational changes of a rat odorant-binding protein Chem. Senses 29 2004 189 198
10. D.A. Breustedt, I.P. Korndorfer, B. Redl, and A. Skerra The 1.8-A crystal structure of human tear lipocalin reveals an extended branched cavity with capacity for multiple ligands J. Biol. Chem. 280 2005 484 493
11. G.M. Morris, D.S. Goodsell, R.S. Halliday, R. Huey, W.E. Hart, R.K. Belew, and A.J. Olson Automated docking using a Lamarckian genetic algorithm and an empirical binding free energy function J. Comput. Chem. 19 1998 1639 1662
12. N. Guex, and M. Peitsch SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling Electrophoresis 18 1997 2714 2723
13. B.J. Glasgow, A.R. Abduragimov, Z.T. Farahbakhsh, K.F. Faull, and W.L. Hubbell Tear lipocalins bind a broad array of lipid ligands Curr. Eye Res. 14 1995 363 372
14. S.Y. Wu, M.D. Pérez, P. Puyo, and L. Sawyer Beta-lactoglobulin binds palmitate within its central cavity J. Biol. Chem. 274 1999 170 174
15. G. Kontopidis, C. Holt, and L. Sawyer The ligand-binding site of bovine beta-lactoglobulin: evidence for a function? J. Mol. Biol. 318 2002 1043 1055
16. L. Ragona, F. Fogolari, L. Zetta, D.M. Pérez, P. Puyol, K. De Kruif, F. Löhr, H. Rüterjans, and H. Molinari Bovine beta-lactoglobulin: interaction studies with palmitic acid Protein Sci. 9 2000 1347 1356
17. G. Beste, F.S. Schmidt, T. Stibora, and A. Skerra Small antibody-like proteins with prescribed ligand specificities derived from the lipocalin fold Proc. Natl. Acad. Sci. USA 96 1999 1898 1903
18. I.P. Korndorfer, G. Beste, and A. Skerra Crystallographic analysis of an "anticalin" with tailored specificity for fluorescein reveals high structural plasticity of the lipocalin loop region Proteins 53 2003 121 129
19. T. Berggård, A. Cohen, P. Persson, A. Lindqvist, T. Cedervall, M. Silow, I.B. Thogersen, J.Å. Jönsson, J.J. Enghild, and B. Åkerström Alpha 1-microglobulin chromophores are located to three lysine residues semiburied in the lipocalin pocket and associated with a novel lipophilic compound Protein Sci. 8 1999 2611 2620
20. R. Ramoni, F. Vincent, S. Grolli, V. Conti, C. Malosse, F.D. Boyer, P. Nagnan-le Meillour, S. Spinelli, C. Cambillau, and M. Tegoni The insect attractant 1-octen-3-ol is the natural ligand of bovine odorant-binding protein J. Biol. Chem. 276 2001 7150 7155
21. T.V. Burova, Y. Choiset, C.K. Jankowski, and T. Haertlé Conformational stability and binding properties of porcine odorant binding protein Biochemistry 38 1999 15043 15051
22. F. Vincent, R. Ramoni, S. Spinelli, S. Grolli, M. Tegoni, and C. Cambillau Crystal structures of bovine odorant-binding protein in complex with odorant molecules Eur. J. Biochem. 271 2004 3832 3842