Oncogenic RAS induces accelerated transition through G2/M and promotes defects in the G2 DNA damage and mitotic spindle checkpoints

Journal of Biological Chemistry

Volumn 281, Issue 7, 2006, Pages 3800-3809

  Knauf, Jeffrey A ^a   Ouyang, Bin ^a   Knudsen, Erik S ^a   Fukasawa, Kenji ^a   Babcock, George ^a   Fagin, James A ^a  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CELLS; GENES; MOLECULAR BIOLOGY;

RAS ONCOPROTEINS; THYROID CELLS; THYROID FOLLICULAR NEOPLASMS;

DNA;

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; B RAF KINASE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; NOCODAZOLE; MITOGEN ACTIVATED PROTEIN KINASE KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; RAS PROTEIN;

ANIMAL CELL; ARTICLE; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE PROGRESSION; CELL CYCLE REGULATION; CELL CYCLE S PHASE; CONTROLLED STUDY; DNA DAMAGE; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GENE ACTIVATION; GENE EXPRESSION; GENOMIC INSTABILITY; MITOSIS SPINDLE; NONHUMAN; ONCOGENE RAS; PRIORITY JOURNAL; RADIATION INJURY; RAT; ANIMAL; CELL DIVISION; CELL LINE; PHYSIOLOGY;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; CELL DIVISION; CELL LINE; DNA DAMAGE; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; G2 PHASE; GENOMIC INSTABILITY; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MITOTIC SPINDLE APPARATUS; RAS PROTEINS; RATS;

EID: 33645213890     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M511690200     Document Type: Article

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