A membrane antibody receptor for noninvasive imaging of gene expression

Gene Therapy

Volumn 13, Issue 5, 2006, Pages 412-420

  Roffler, S R ^a   Wang, H E ^b   Yu, H M ^b   Chang, W D ^c   Cheng, C M ^c   Lu, Y L ^d   Chen, B M ^a   Cheng, T L ^c  

^a INSTITUTE OF BIOMEDICAL SCIENCES   (Taiwan)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

^c KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^d CHIA NAN UNIVERSITY OF PHARMACY AND SCIENCE   (Taiwan)

Author keywords

Dansyl; Hapten; Noninvasive imaging; Single chain antibody; Surface expression

Indexed keywords

DANSYL CHLORIDE; HAPTEN; PENTETATE INDIUM IN 113M;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN ANTIBODY REACTION; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG DISTRIBUTION; DRUG STABILITY; DRUG STRUCTURE; GENE EXPRESSION; GENE TARGETING; IMAGING SYSTEM; IN VITRO STUDY; IN VIVO STUDY; MELANOMA CELL; MOUSE; NON INVASIVE MEASUREMENT; NONHUMAN; PLASMA HALF LIFE; PRIORITY JOURNAL; RADIOACTIVITY; REPORTER GENE; RETROVIRUS VECTOR; SCINTILLATION CAMERA; SENSITIVITY AND SPECIFICITY; STRUCTURE ANALYSIS; TISSUE DISTRIBUTION; TUMOR IMMUNITY; VIRAL GENE DELIVERY SYSTEM; WHOLE BODY SCINTISCANNING;

ANIMALS; ANTIBODY SPECIFICITY; GENE EXPRESSION; GENE THERAPY; GENETIC ENGINEERING; GENETIC VECTORS; HAPTENS; HELA CELLS; HUMANS; INDIUM RADIOISOTOPES; MELANOMA, EXPERIMENTAL; MICE; MICE, INBRED C57BL; MICROSCOPY, PHASE-CONTRAST; PENTETIC ACID; PHOSPHATIDYLCHOLINES; PROTEIN BINDING; RECEPTORS, CELL SURFACE; RECEPTORS, FC; RETROVIRIDAE;

ANIMALIA;

EID: 33645149227     PISSN: 09697128     EISSN: 14765462     Source Type: Journal    
DOI: 10.1038/sj.gt.3302671     Document Type: Article

References (40)

1. Hoffman RM. In vivo imaging with fluorescent proteins: The new cell biology. Acta Histochem 2004; 106: 77-87.
2. Misteli T, Spector DL. Applications of the green fluorescent protein in cell biology and biotechnology. Nat Biotechnol 1997; 15: 961-964.
3. Yang M, Baranov E, Jiang P, Sun FX, Li XM, Li L et al. Whole-body optical imaging of green fluorescent protein-expressing tumors and metastases. Proc Natl Acad Sci USA 2000; 97: 1206-1211.
4. Jacobs Jr WR, Barletta RG, Udani R, Chan J, Kalkut G, Sosne G et al. Rapid assessment of drug susceptibilities of Mycobacterium tuberculosis by means of luciferase reporter phages. Science 1993; 260: 819-822.
5. Leo BM, Li X, Balian G, Anderson DG. In vivo bioluminescent imaging of virus-mediated gene transfer and transduced cell transplantation in the intervertebral disc. Spine 2004; 29: 838-844.
6. Ray P, De A, Min JJ, Tsien RY, Gambhir SS. Imaging tri-fusion multimodality reporter gene expression in living subjects. Cancer Res 2004; 64: 1323-1330.
7. de Vries EF, van Dillen IJ, van Waarde A, Willemsen AT, Vaalburg W, Mulder NH et al. Evaluation of [18F]FHPG as PET tracer for HSVtk gene expression. Nucl Med Biol 2003; 30: 651-660.
8. Gambhir SS, Barrio JR, Wu L, Iyer M, Namavari M, Satyamurthy N et al. Imaging of adenoviral-directed herpes simplex virus type 1 thymidine kinase reporter gene expression in mice with radiolabeled ganciclovir. J Nucl Med 1998; 39: 2003-2011.
9. Tjuvajev JG, Finn R, Watanabe K, Joshi R, Oku T, Kennedy J et al. Noninvasive imaging of herpes virus thymidine kinase gene transfer and expression: A potential method for monitoring clinical gene therapy. Cancer Res 1996; 56: 4087-4095.
10. Gambhir SS, Bauer E, Black ME, Liang Q, Kokoris MS, Barrio JR et al. A mutant herpes simplex virus type 1 thymidine kinase reporter gene shows improved sensitivity for imaging reporter gene expression with positron emission tomography. Proc Natl Acad Sci USA 2000; 97: 2785-2790.
11. Richard JC, Zhou Z, Ponde DE, Dence CS, Factor P, Reynolds PN et al. Imaging pulmonary gene expression with positron emission tomography. Am J Respir Crit Care Med 2003; 167: 1257-1263.
12. Tjuvajev JG, Avril N, Oku T, Sasajima T, Miyagawa T, Joshi R et al. Imaging herpes virus thymidine kinase gene transfer and expression by positron emission tomography. Cancer Res 1998; 58: 4333-4341.
13. Johnson AA, Ray AS, Hanes J, Suo Z, Colacino JM, Anderson KS et al. Toxicity of antiviral nucleoside analogs and the human mitochondrial DNA polymerase. J Biol Chem 2001; 276: 40847-40857.
14. Morin KW, Duan W, Xu L, Zhou A, Moharram S, Knaus EE et al. Cytotoxicity and cellular uptake of pyrimidine nucleosides for imaging herpes simplex type-1 thymidine kinase (HSV-1 TK) expression in mammalian cells. Nucl Med Biol 2004; 31: 623-630.
15. Bonini C, Ferrari G, Verzeletti S, Servida P, Zappone E, Ruggieri L et al. HSV-TK gene transfer into donor lymphocytes for control of allogeneic graft-versus-leukemia. Science 1997; 276: 1719-1724.
16. Russo V, Tanzarella S, Dalerba P, Rigatti D, Rovere P, Villa A et al. Dendritic cells acquire the MAGE-3 human tumor antigen from apoptotic cells and induce a class I-restricted T cell response. Proc Natl Acad Sci USA 2000; 97: 2185-2190.
17. Haack K, Linnebacher M, Eisold S, Zoller M, von Knebel Doeberitz M, Gebert J. Induction of protective immunity against syngeneic rat cancer cells by expression of the cytosine deaminase suicide gene. Cancer Gene Ther 2000; 7: 1357-1364.
18. Haberkorn U, Oberdorfer F, Gebert J, Morr I, Haack K, Weber K et al. Monitoring gene therapy with cytosine deaminase: In vitro studies using tritiated-5-fluorocytosine. J Nucl Med 1996; 37: 87-94.
19. 18F]fluoroethyl)spiperone: In vivo biochemical and kinetic characterization in rodents, nonhuman primates, and humans. J Cereb Blood Flow Metab 1989; 9: 830-839.
20. MacLaren DC, Gambhir SS, Satyamurthy N, Barrio JR, Sharfstein S, Toyokuni T et al. Repetitive, non-invasive imaging of the dopamine D2 receptor as a reporter gene in living animals. Gene Therapy 1999; 6: 785-791.
21. Bunzow JR, Van Tol HH, Grandy DK, Albert P, Salon J, Christie M et al. Cloning and expression of a rat D2 dopamine receptor cDNA. Nature 1988; 336: 783-787.
22. Wolf G. Vitamin A functions in the regulation of the dopaminergic system in the brain and pituitary gland. Nutr Rev 1998; 56: 354-355.
23. Beom S, Cheong D, Torres G, Caron MG, Kim KM. Comparative studies of molecular mechanisms of dopamine D2 and D3 receptors for the activation of extracellular signal regulated kinase. J Biol Chem 2004; 279: 28304-28314.
24. Strange PG. Aspects of the structure of the D2 dopamine receptor. Trends Neurosci 1990; 13: 373-378.
25. Weissleder R, Moore A, Mahmood U, Bhorade R, Benveniste H, Chiocca EA et al. In vivo magnetic resonance imaging of transgene expression. Nat Med 2000; 6: 351-355.
26. Liao KW, Chen BM, Liu TB, Tzou SC, Lin YM, Lin KF et al. Stable expression of chimeric anti-CD3 receptors on mammalian cells for stimulation of antitumor immunity. Cancer Gene Ther 2003; 10: 779-790.
27. Cheng TL, Liao KW, Tzou SC, Cheng CM, Chen BM, Roffler SR. Hapten-directed targeting to single-chain antibody receptors. Cancer Gene Ther 2004; 11: 380-388.
28. Liao KW, Lo YC, Roffler SR. Activation of lymphocytes by anti-CD3 single-chain antibody dimers expressed on the plasma membrane of tumor cells. Gene Therapy 2000; 7: 339-347.
29. Chen IY, Wu JC, Min JJ, Sundaresan G, Lewis X, Liang Q et al. Micro-positron emission tomography imaging of cardiac gene expression in rats using bicistronic adenoviral vector-mediated gene delivery. Circulation 2004; 109: 1415-1420.
30. Levenson VV, Transue ED, Roninson IB. Internal ribosomal entry site-containing retroviral vectors with green fluorescent protein and drug resistance markers. Hum Gene Ther 1998; 9: 1233-1236.
31. Yu Y, Annala AJ, Barrio JR, Toyokuni T, Satyamurthy N, Namavari M et al. Quantification of target gene expression by imaging reporter gene expression in living animals. Nat Med 2000; 6: 933-937.
32. Chou WC, Liao KW, Lo YC, Lang SY, Yeh MY, Roffler SR et al. Expression of chimeric monomer and dimer proteins on the plasma membrane of mammalian cells. Biotechnol Bioeng 1999; 65: 160-169.
33. Liao KW, Chou WC, Lo YC, Roffler SR. Design of transgenes for efficient expression of active chimeric proteins on mammalian cells. Biotechnol Bioeng 2001; 73: 313-323.
34. Martell A, Smith RM. Critical Stability Constants, vol. 6. Plenum Press: New York, 1986.
35. Coloma MJ, Morrison SL. Design and production of novel tetravalent bispecific antibodies. Nat Biotechnol 1997; 15: 159-163.
36. Morrison SL, Porter SB, Trinh KR, Wims LA, Denham J, Oi VT. Variable region domain exchange influences the functional properties of IgG. J Immunol 1998; 160: 2802-2808.
37. Northrop JP, Bednarski M, Barbieri SO, Lu AT, Nguyen D, Varadarajan J et al. Cell surface expression of single chain antibodies with applications to imaging of gene expression in vivo. Eur J Nucl Med Mol Imaging 2003; 30: 1292-1298.
38. Farinas J, Verkman AS. Receptor-mediated targeting of fluorescent probes in living cells. J Biol Chem 1999; 274: 7603-7606.
39. Andrianaivo F, Lecocq M, Wattiaux-De Coninck S, Wattiaux R, Jadot M. Hydrodynamics-based transfection of the liver: Entrance into hepatocytes of DNA that causes expression takes place very early after injection. J Gene Med 2004; 6: 877-883.
40. Wang CH, Jawan B, Lee TH, Hung KS, Chou WY, Lu CN et al. Single injection of naked plasmid encoding alpha-melanocyte-stimulating hormone protects against thioacetamide-induced acute liver failure in mice. Biochem Biophys Res Commun 2004; 322: 153-161.