The use of alternative medicine for the treatment of insomnia in the elderly

Psychogeriatrics

Volumn 6, Issue 1, 2006, Pages 21-30

  Cherniack, Evan Paul ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

Alternative medicine; Insomnia

Indexed keywords

BENZODIAZEPINE DERIVATIVE; CHINESE DRUG; GLYCYRRHIZA EXTRACT; HERBACEOUS AGENT; HYPERICUM PERFORATUM EXTRACT; KAVA; LAVENDER OIL; MATRICARIA CHAMOMILLA EXTRACT; MELATONIN; MERCURY SULFIDE; PLACEBO; PLANT EXTRACT; PLANT MEDICINAL PRODUCT; PYRIDOXINE; SEMEN ZIZIPHI EXTRACT; SUANZAORENTANG; UNCLASSIFIED DRUG; VALERIAN; YOKU KAN SAN KA CHIMPI HANGE;

ABDOMINAL PAIN; ACUPUNCTURE; AGED; ALTERNATIVE MEDICINE; CLINICAL TRIAL; COMA; CONGESTIVE HEART FAILURE; DIZZINESS; DRUG EFFICACY; DRUG ERUPTION; DRUG MECHANISM; FATIGUE; GASTROINTESTINAL SYMPTOM; GERIATRIC CARE; HEADACHE; HUMAN; HYPOTENSION; HYPOTHERMIA; INSOMNIA; INTRAOCULAR PRESSURE; JUJUBE; KIDNEY INJURY; LIVER TOXICITY; MAGNETISM; MASSAGE; MUSIC THERAPY; MYDRIASIS; NAUSEA; PRIORITY JOURNAL; RANDOMIZATION; REVIEW; RISK BENEFIT ANALYSIS; SEMEN ZIZIPHI; SIDE EFFECT; SLEEP DISORDER; SOMNOLENCE; TAI CHI; THORAX PAIN; TREMOR; WHITE NOISE;

EID: 33645145267     PISSN: 13463500     EISSN: 14798301     Source Type: Journal    
DOI: 10.1111/j.1479-8301.2006.00107.x     Document Type: Review

References (111)

1. Schneider DL. Insomnia: Safe and effective therapy for sleep problems in the older patient. Geriatrics 2002; 57: 24-35.
2. Drake CL, Roehrs T, Roth T. Insomnia causes consequences, and therapeutics: An overview. Depress Anxiety 2003; 18: 163-176.
3. Busto UE, Sproule BA, Knight K et al. Use of prescription and nonprescription hypnotics in a Canadian elderly population. Can J Clin Pharmacol 2001; 8: 213-221.
4. Astin JA, Pelletier KR, Marie A et al. Complementary and alternative medicine use among elderly persons: One-year analysis of a Blue Shield Medicare supplement. J Gerontol A Biol Sci Med Sci 2000; 55: M4-M9.
5. Foster DF, Phillips RS, Hamel MB et al. Alternative medicine use in older Americans. J Am Geriatr Soc 2000; 48: 1560-1565.
6. Cherniack EP, Senzel R, Pan CX. Female gender and education are the strongest correlates of use of alternative medicine by the elderly. J Altern Complement Med 2001; 7: 277-280.
7. Barnes PM, Powell-Griner E, McFann K. Complementary and alternative medicine use among adults: United States, 2002. Adv Data 2004; 343: 1-19.
8. Coulter ID, Willis EM. The rise and rise of complementary medicine: A sociological perspective. Med J Aust 2004; 180: 587-589.
9. Furnam A. Why do the elderly use complementary and alternative medicine? In: Cherniack EP, Cherniack N, eds. Alternative Medicine for the Elderly. Berlin: Springer, 2003; 9-25.
10. Sack RL, Lewy AL, Hughes R. Use of melatonin for sleep and circadian rhythm disorders. Ann Med 1998; 30: 115-121.
11. Sack RL, Hughes RJ, Edgar DM et al. Sleep-promoting effects of melatonin: At what dose, in whom, under what conditions, and by what mechanisms? Sleep 1997; 20: 908-915.
12. Monti JM, Cardinali DP. A critical assessment of melatonin affect on sleep in human. Biol Signals Recept 2000; 9: 328-339.
13. Waldhauser F, Kovaics J, Reiter E. Age-related changes in melatonin levels in humans and its potential consequences for sleep disorders. Exp Gerontol 1998; 33: 759-772.
14. Olde Rikkert MG, Rigaud AS. Melatonin in elderly patients with insomnia. A systematic review. Z Gerontol Geriatr 2001; 34: 491-497.
15. Leger D, Laudon M, Zisapel N. Nocturnal 6-sulfaoxymelatonin excretion in insomnia and its relation to the response to melatonin replacement therapy. Am J Med 2004; 116: 91-95.
16. Haimov I, Laudon M, Zisapel N. Sleep disorders and melatonin rhythms in elderly people. BMJ 1994; 309: 167.
17. Baskett JJ, Wood PC, Broad JB. Melatonin in older people with age-related sleep maintenance problems: A comparison with age matched normal sleepers. Sleep 2001; 24: 418-424.
18. Morera AL, Henry M, Villaverde-Ruiz ML, Gracia-Marco R. Efficiency of melatonin in the treatment of insomnia. Actas Esp Psiquiatr 2000; 28: 325-329.
19. Hughes RJ, Sack RL, Lewy AJ. The role of melatonin and circadian phase in age-related sleep-maintenance insomnia: Assessment in a clinical trial of melatonin replacement. Sleep 1998; 21: 52-68.
20. Hughes RJ, Badia P. Sleep-promoting and hypothermic effects of daytime melatonin administration in humans. Sleep 1997; 20: 124-131.
21. Matsumoto M. The hypnotic effects of melatonin on diurnal sleep in humans. Psychiatry Clin Neurosci 1999; 53: 243-245.
22. Dawson D, Encel N, Lushington K. Shift work and sleep deprivation: improving adaptation to stimulated night shift: Timed exposure to bright light versus daytime melatonin administration. Sleep 1995; 18: 11-21.
23. Lushington K, Pollard K, Lack L et al. Melatonin and circadian rhythms: daytime melatonin administration in elderly good and poor sleepers: effects on core body temperature and sleep latency. Sleep 1997; 20: 1135-1144.
24. Zhdanova IV, Wurtman RJ, Regan MM et al. Melatonin treatment for age- related insomnia. J Clin Endocrinol Metab 2001; 86: 4727-4730.
25. Peck JS, LeGoff DB, Ahmed I et al. Cognitive effects of exogenous melatonin administration in elderly persons: A pilot study. Am J Geriatr Psychiatry 2004; 12: 432-436.
26. Dahlitz M, Alvarez B, Vignau J et al. Delayed sleep phase syndrome to melatonin. Lancet 1991; 337: 1121-1124.
27. Andrade C, Srihari BS, Reddy KP. Melatonin in medically-ill patients with insomnia: A placebo-controlled study. J Clin Psychiatry 2001; 62: 41-45.
28. Garfinkel D, Laudon M, Nof D et al. Improvement in sleep quality in elderly people by controlled-release melatonin. Lancet 1995; 346: 541-544.
29. Haimov I, Peretz L, Laudon M et al. Melatonin replacement therapy of elderly insomniacs. Sleep 1995; 18: 598-603.
30. Baskett JJ, Broad JB, Wood PC et al. Does melatonin improve sleep in older people? A randomized crossover trial. Age Ageing 2003; 32: 164-170.
31. Ellis CM, Lemmins G, Parkes JD. Melatonin and insomnia. J Sleep Res 1996; 5: 61-65.
32. Almeida Montes LG, Ontiveros Uribe MP, Cortes Sotres J. Treatment of insomnia with melatonin: A double blind placebo controlled, crossover study. J Psychiatr Neurosci 2003; 28: 191-196.
33. Cardinali DP, Brusco LI, Liberczuk C et al. The use of melatonin in Alzheimer's disease. Neuroendocrinol Lett 2002; 23: 20-23.
34. Singer C, Tractenberg RE, Kaye J et al. A multicenter, placebo-controlled trial of melatonin for sleep disturbance in Alzheimer's disease. Sleep 2003; 26: 893-901.
35. Garfinkel D, Laudon M, Zisapel N. Improvement of sleep quality by controlled-release melatonin in benzodiazepine-treated insomniacs. Arch Gerontol Geriatr 1997; 24: 223-231.
36. Youngstedt SD, Kripke DF, Elliot JA et al. Circadian abnormalities in older adults. J Pineal Res 2001; 31: 264-272.
37. Arendt J. Safety of melatonin in long-term use (?) J Biol Rhythms 1997; 12: 673-681.
38. Samples JR, Krause G, Lewy AJ. Effect of melatonin on intraocular pressure. Curr Eye Res 1988; 7: 649-653.
39. Cauffield JS, Forbes HJM. Dietary supplements used in the treatment of depression anxiety and sleep disorders. Lippincott's Prim Care Prac 1999; 3: 290-304.
40. Guardiola-Lemaitre B. Toxicology of melatonin. J Biol Rhythms 1997; 12: 697-706.
41. Rindone JP, Achacoso R. Effect of melatonin on serum lipids in patients with hypercholesterolemia: A pilot study. Am J Ther 1997; 4: 409-411.
42. Seabra ML, Bignotto M, Pinto LR et al. Randomized, double-blind clinical trial, controlled with placebo, of the toxicology of chronic melatonin treatment. J Pineal Res 2000; 29: 193-200.
43. Hadley S, Petry JJ. Valerian. Am Fam Physician 2003; 67: 1755-1758.
44. Ortiz JG, Nieves-Natal J, Chavez P. Effects of Valeriana officinalis extracts on [3H]flunitrazepam binding, synaptosomal [3H]GABA uptake, and hippocampal [3H]GABA release. Neurochem Res 1999; 24: 1373-1378.
45. Houghton PJ. The scientific basis for the reputed activity of Valerian. J Pharm Pharmacol 1999; 51: 505 -512.
46. Stevinson C, Ernst E. Valerian for insomnia: A systematic review of randomized clinical trials. Sleep Med 2000; 1: 91-99.
47. Coxeter PD, Schluter PJ, Easwood HL et al. Valerian does not appear to reduce symptoms for patients with chronic insomnia in general practice using a series of randomized n-of-1 trials. Comp Ther Med 2003; 11: 215-222.
48. Hallam KT, Olver JS, McGrath C. Comparative cognitive and psychomotor effects of single doses of Valeriana officianalis and triazolam in healthy volunteers. Hum Psychopharmacol Clin Exp 2003; 18: 619-625.
49. Leathwood PD, Chauffard F. Quantifying the effects of mild sedatives. J Psychiatr Res 1882-1983; 17: 115-122.
50. Leathwood PD, Chauffard F, Heck E et al. Aqueous extract of valerian root improves sleep quality in man. Pharmacol Biochem Behav 1982; 17: 65-67.
51. Pallesen S, Bjorvatn B, Nordhus IH et al. Valerian as a sleeping aid? Tidsskr Nor Laegeforen 2002; 122: 2857-2859.
52. Leathwood PD, Chauffard F. Aqueous extract of valerian reduces latency to fall asleep in man. Planta Med 1985; 2: 144-147.
53. Donath F, Ouispe S, Diefenbach K et al. Critical evaluation of the effect of valerian extract on sleep structure and sleep quality. Pharmacopsychiatry 2000; 33: 47-53.
54. Lindahl O, Lindwall L. Double blind study of a valerian preparation. Pharmacol Biochem Behav 1989; 32: 1065-1066.
55. Schulz H, Stolz C, Muller J. The effect of valerian extract on sleep polygraphy in poor sleepers: A pilot study. Pharmacopsychiatry 1994; 27: 147-151.
56. Kamm-Kohl AV, Jansen W, Brockmann P. Moderne Baldriantherapie gegen vervose Storungen in Senium. Medwelt 1984; 35: 1450-1454.
57. Dorn M. Efficacy and tolerability of Baldrian versus oxazepam in non-organic and non-psychiatric insomniacs: A randomised, double-blind, clinical, comparative study. Forsch Komplementarmed Klass Naturheilkd 2000; 7: 79-84.
58. Ziegler G, Ploch M, Miettinen-Baumann A et al. Efficacy and tolerability of valerian extract LI 156 compared with oxazepam in the treatment of non-organic insomnia - a randomized, double-blind, comparative clinical study. Eur J Med Res 2002; 7: 480-486.
59. Poyares DR, Guilleminault C, Ohayon MM et al. Can valerian improve the sleep of insomniacs after benzodiazepine withdrawal? Prog Neuropsychopharmacol Biol Psych 2002; 26: 539-545.
60. Garges H, Varia I, Doraiswamy PM. Cardiac complications and delirium associated with valerian root withdrawal. JAMA 1998; 180: 1566-1567.
61. Boniel T, Dannon P. The safety of herbal medicines in the psychiatric practice. Harefuah 2001; 140: 780-783.
62. Hardy M, Kirk-Smith MD, Stretch DD. Replacement of drug treatment for insomnia by ambient odor. Lancet 1995; 346: 701.
63. Block KI, Gyllenhaal C, Mead MN. Safety and efficacy of herbal sedatives in cancer care. Integr Cancer Ther 2004; 3: 128-148.
64. Brownfield A. Aromatherapy in arthritis: A study. Nurse Stand 1998; 13: 34-35.
65. Richards K, Nagel C, Markie M et al. Use of complementary and alternative therapies to promote sleep in critically ill patients. Crit Care Nurs Clin N Am 2003; 15: 329-340.
66. Cannard G. Complementary therapies. On the scent of a good night's sleep. Nurs Stand 1995; 9: 21.
67. Schmitz M, Jackel M. Comparative study for assessing quality of life of patients with exogenous sleep disorders (temporary sleep onset and sleep interruption disorders) treated with a hops-valerian preparation and a benzodiazepine drug. Wien Med Wochenschr 1998; 148: 291-298.
68. Muller-Limmroth W, Ehrenstein W. Experimental studies of the effects of Seda-Kneipp on the sleep of sleep disturbed subjects; implications for the treatment of different sleep disturbances. Med Klin 1977; 72: 1119-1125.
69. Schellenberg R, Sauer S, Abourashed EA et al. The fixed combination of valerian and hops (Ze91019) acts via a central adenosine mechanism. Planta Med 2004; 70: 594-597.
70. Müller CE, Schumacher B, Brattström A et al. Interactions of valerian extracts and a fixed valerian-hop extract combination with adenosine receptors. Life Sci 2002; 71: 1939-1949.
71. Hänsel R, Wohlfart R, Cooper H. Sedative-hypnotic compounds in the exhalation of hops, II. Z Naturforsch 1980; 35: 1096-1097.
72. Wheatley D. Kava and valerian in the treatment of stress-induced insomnia. Phytotherapy Res 2001; 15: 549-551.
73. Almeida JC, Grimsley EW. Coma from the health food store: Interaction between kava and aprazolam. Ann Int Med 1996; 125: 940-941.
74. Chung KF, Lee CKY. Over-the-counter sleeping pills: A survey of use in Hong Kong and a review of their constituents. Gen Hosp Psychiatry 2002; 24: 430-435.
75. Ma E. Efficacy and pharmacological studies of suanzaorenanshen capsule in the treatment of insomnia Chinese. J Int Trad Wed Med 1989; 9: 85-87.
76. Zhang ZY. Insomnia treated by zinianshentang: A report of 36 cases. J Hunan Coll Trad Chin Med 1997; 17: 18-20.
77. Qiao ZG, Qiao YH, Qiao YZ. Insomnia treated by baileanshentang: A report of 226. Guang Ming J Trad Chin Med 1998; 76: 46-48.
78. Zhao CC, Yang YQ, Shao MQ et al. Insomnia treated by cuimianyin: A report of 63 cases. Zhong Guo Min Jian Liao Fa 1999; 4: 29-30.
79. Pan SB. Insomnia treated by dingmeitang: A report of 25 cases. New Trad Chin Med 1997; 29: 31-32.
80. Chen HC, Hsieh MT, Shibuya TK. Suanzaorentang versus diazepam: A controlled double-blind study in anxiety. Int J Clin Pharmacol Ther Toxicol 1986; 24: 646-650.
81. Chen HC, Hsieh MT. Clinical trial of suanzaorentang in the treatment of insomnia. Clin Ther 1985; 7: 334-335.
82. Kanba S, Yamada K, Mizushima H et al. Use of herbal medicine for treating psychiatric disorders in Japan. In: Kamba S, Richelson E, eds. Herbal Medicines for Neuropsychiatric Diseases: Current Developments and Research, New York: Brunner/Mazel, 1999; 3-14.
83. Zheng HZ, Dong AH, She J. Modern Study of Chinese Medicine. Beijing: Xue Yuan Press, 1997.
84. Lee P. Side effects of glycyrrhizae radix Hunan. J Trad Chin Med 1998; 14: 59.
85. Liu SY. Some basic features of the new sleep-aid tea (SAT) for the treatment of insomnia. Sleep Res Online 2000; 3: 49-52.
86. Wing YK. Herbal treatment of insomnia. Hong Kong Med J 2001; 7: 392-402.
87. Aizawa R, Kanbayashi T, Saito Y et al. Effects of Yoku-kan-san-ka-chimpi-hange on the sleep of normal healthy adult subjects. Psychiatry Clin Neurosci 2002; 56: 303-304.
88. Ebben M, Leguerica A, Spielman A. Effect of pyridoxine on dreaming: A preliminary study. Percept Mot Skills 2002; 94: 135-140.
89. Saletu B, Grünberger J, Lesch O. Effect of nootropic drugs on normal and disturbed sleep of the elderly: Controlled studies with pyridoxilate and street noise. Wien Klin Wochenschr 1984 ; 96: 817-822.
90. Holsboer-Trachsler E. Phytotherapeutic drugs and sleep. Schweiz Rundsch Med Prax 2000; 89: 2178-2182.
91. Schulz H, Jobert M. Effects of hypericum extract on the sleep EEG in older volunteers. J Geriatr Psychiatry Neurol 1994; 7: 39S-43S.
92. Medina JH, Viola H, Wolfman C et al. Neuroactive flavonoids: New ligands fo the benzodiazepine receptors. Phytomedicine 1998; 5: 235-243.
93. Gould L, Reddy CV, Gomprecht RF. Cardiac effects of chamomile tea. J Clin Pharmacol 1973; 13: 475-479.
94. Viola H, Wasowski C, Levi de Stein M et al. Apigenin, a component of Matricaria recutita flowers, is a central benzodiazepine receptors-ligand with anxiolytic effects. Planta Med 1995; 61: 213-216.
95. Berry M. The chamomiles. Pharm J 1995; 254: 191-193.
96. Mann C, Staba EJ. The chemistry, pharmacology, and commercial formulations of chamomile. Herbs Spices Med Plants 1984; 1: 235-280.
97. Mills S. The Essential Book of Herbal Medicine, 2nd edn. London: Penguin Books Ltd, 1991; 677.
98. Richards KC. Effect of a back massage and relaxation intervention on sleep in critically ill inpatients. Am J Crit Care 1998; 7: 288-299.
99. Mcdowell JA, Mion LC, Lydon TJ. A Nonpharmacologic sleep protocol for hospitalized older patients. J Am Geriatr Soc 1998; 56: 700-705.
100. Spence DW, Kayumov L, Chen A et al. Acupuncture increases nocturnal melatonin secretion and reduces insomnia and anxiety: A preliminary report. J Neuropsychiatry Clin Neurosci 2004; 16: 19-28.
101. Sok SR, Erlen JA, Kim KB. Effects of acupuncture therapy on insomnia. J Adv Nurs 2003; 44: 375-384.
102. Lu Z. Scalp and body acupuncture for treatment of senile insomnia-a report of 83 cases. J Trad Chin Med 2002; 22: 193-194.
103. Dongli S. Acupuncture treatment of insomnia. J Trad Chin Med 2003; 23: 136-137.
104. Chen ML, Lin LC, Wu SC, Lin JG. The effectiveness of acupressure in improving the quality of sleep of institutionalized residents. J Gerontol 1999; 54: 389-394.
105. Johnson JE. The use of music to promote sleep in older women. J Community Health Nurs 2003; 20: 27-35.
106. Levin YI. 'Brain music' in the treatment of patients with insomnia. Neurosci Behav Phys 1998; 28: 330-335.
107. Li F, Fisher KJ, Harmer P et al. Tai chi and self-rated quality of sleep and daytime sleepiness in older adults: A randomized controlled trial. J Am Geriatr Soc 2004; 52: 892-900.
108. Pelka RB, Jaenicke C, Gruenwald J. Impulse magnetic-field therapy for insomnia: A double-blind, placebo controlled study. Adv Ther 2001; 18: 174-180.
109. Suen LKP, Wong TKS, Leung AWN et al. The long-term effects of auricular therapy using magnetic pearls on elderly with insomnia. Comp Ther Med 2003; 11: 85-92.
110. Lopez HH, Bracha AS, Bracha HS. Evidence based complementary intervention for insomnia. Hawaii Med J 2002; 61: 192-193.
111. Williamson JW. The effects of ocean sounds on sleep after coronary artery bypass graft surgery. Am J Crit Care 1992; 1: 91-97.