The role of prostaglandin E receptor-dependent signaling via cAMP in Mdr1b gene activation in primary rat hepatocyte cultures

Journal of Pharmacology and Experimental Therapeutics

Volumn 317, Issue 1, 2006, Pages 378-386

  Ziemann, Christina ^a,b   Riecke, Armin ^a   Rüdell, Gudrun ^a   Oetjen, Elke ^a   Steinfelder, Hans J ^a   Lass, Christian ^a   Kahl, Georg F ^a   Hirsch Ernst, Karen I ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b FRAUNHOFER INSTITUTE FOR TOXICOLOGY AND EXPERIMENTAL MEDICINE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

7 [5 (4 BIPHENYLYLMETHOXY) 2 MORPHOLINO 3 OXOCYCLOPENTYL] 4 HEPTENOIC ACID; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; MESSENGER RNA; MISOPROSTOL; MULTIDRUG RESISTANCE PROTEIN 1; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; PROSTAGLANDIN E RECEPTOR;

ANIMAL CELL; ARTICLE; CELL CULTURE; CONTROLLED STUDY; DNA FLANKING REGION; DRUG EFFECT; GENE ACTIVATION; GENE CONSTRUCT; LIVER CELL; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; UPREGULATION;

1-METHYL-3-ISOBUTYLXANTHINE; 8-BROMO CYCLIC ADENOSINE MONOPHOSPHATE; ANIMALS; CELLS, CULTURED; CREB-BINDING PROTEIN; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; ENZYME INHIBITORS; GENE EXPRESSION REGULATION; GENES, REPORTER; HEPATOCYTES; ISOQUINOLINES; MALE; MISOPROSTOL; P-GLYCOPROTEINS; RATS; RATS, WISTAR; RECEPTORS, PROSTAGLANDIN E; SIGNAL TRANSDUCTION; SULFONAMIDES;

EID: 33645110520     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.105.094193     Document Type: Article

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