PGE2 stimulates O2 uptake in hepatic parenchymal cells: Involvement of the cAMP-dependent protein kinase

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 277, Issue 5 40-5, 1999, Pages

  Qu, Wei ^a   Graves, Lee M ^a   Thurman, Ronald G ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

Mitochondria; Prostaglandin E2; Protein kinase A

Indexed keywords

ADENOSINE TRIPHOSPHATE; BUCLADESINE; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; OXYGEN; PROSTAGLANDIN E RECEPTOR; PROSTAGLANDIN E1 DERIVATIVE; PROSTAGLANDIN E2; PROSTAGLANDIN E2 DERIVATIVE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVE SITE; FEMALE; LIVER MITOCHONDRION; LIVER PARENCHYMA; MITOCHONDRIAL RESPIRATION; NONHUMAN; OXYGEN CONSUMPTION; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION;

EID: 33747213424     PISSN: 01931857     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpgi.1999.277.5.g1048     Document Type: Article

References (29)

1. Altin, J. G., and F. L. Bygrave. Non-parenchymal cells as mediators of physiological responses in liver. Mol. Cell. Biochem. 83: 3-14, 1988.
2. 2 mediates the stimulation of glycogenolysis in the liver by phorbol ester. Biochem. J. 250: 77-80, 1988.
3. Chance, B. The energy-linked reaction of calcium with mitochondria. J. Biol. Chem. 240: 2729-2748, 1965.
4. Chijiwa, T., A. Mishima, M. Hagiwara, M. Sano, K. Hayashi, T. Inoue, K. Naito, T. Toshioka, and H. Hidaka. Inhibition of forskolin-induced neurite outgrowth and protein phosphorylation by a newly snythesized selective inhibitor of cyclic AMP-dependent protein kinase, N-[2-(p-bromocinnamylamino)ethyl]-5-isoquinolinesulfonamide (H-89), of PC12D pheochromocytoma cells. J. Biol. Chem. 265: 5267-5272, 1990.
5. Coleman, R. A., I. Kennedy, P. P. A. Humphrey, K. Bunce, and P. Lumley. Prostanoids and their receptors. In: Comprehensive Medicinal Chemistry, edited by C. Hansch, P. G. Sammes, J. B. Taylor, and J. C. Emmett. Oxford, UK: Pergamon, 1989, p. 643-714.
6. Crompton, M., and T. P. Goldstone. The involvement of calcium in the stimulation of respiration in isolated rat hepatocytes by adrenergic agonists and glucagon. FEBS Lett. 204: 198-202, 1986.
7. 2, parathyroid hormone, and epidermal growth factor on mitogenesis, signaling, and primary response genes in UMR 106-01 osteoblast-like cells. Endocrinology 131: 2113-2119, 1992.
8. 1 subtype. J. Biol. Chem. 268: 26767-26772, 1993.
9. Gornall, A. G., C. J. Bardawill, and M. M. David. Determination of serum proteins by means of the biuret reaction. J. Biol. Chem. 177: 751-766, 1949.
10. Graves, L. M., K. E. Bornfeldt, E. W. Raines, B. C. Potts, S. G. Macdonald, R. Ross, and E. G. Krebs. Protein kinase A antagonizes platelet-derived growth factor-induced signaling by mitogen-activated protein kinase in human arterial smooth muscle cells. Proc. Natl. Acad. Sci. USA 90: 10300-10304, 1993.
11. Graves, L. M., K. E. Bornfeldt, J. S. Sidhu, G. M. Argast, E. W. Raines, R. Ross, C. C. Leslie, and E. G. Krebs. Platelet-derived growth factor stimulates protein kinase A through a mitogen-activated protein kinase-dependent pathway in human arterial smooth muscle cells. J. Biol. Chem. 271: 505-511, 1996.
12. 2+ indicators with greatly improved fluorescence properties. J. Biol. Chem. 260: 3440-3450, 1985.
13. Inoue, S., and S. Kawanishi. Hydroxyl radical production and human DNA damage induced by ferric nitrilotriacetate and hydrogen peroxide. Cancer Res. 47: 6522-6527, 1987.
14. Kizaki, Z., R. G. Thurman. Stimulation of oxygen uptake by glucagon is oxygen dependent in perfused rat liver. Am. J. Physiol. 256 (Gastrointest. Liver Physiol. 19): G369-G376, 1989.
15. Konger, R. L., R. Malaviya, and A. P. Pentland. Growth regulation of primary human ketatinocytes by prostaglandin E receptor EP2 and EP3 subtypes. Biochim. Biophys. Acta 1401: 221-234, 1998.
16. 2+ release from mitochondria by the oxidation reduction state of pyridine nucleotides. Proc. Natl. Acad. Sci. USA 715: 1690-1694, 1978.
17. Masaracchia, R. A., B. E. Kemp, and D. A. Walsh. Histone 4 phosphotransferase activities in proliferating lymphocytes. Partial purification and characterization of an enzyme specific for Ser-47. J. Biol. Chem. 252: 7109-7117, 1977.
18. Pertoft, H., and B. Smedsrod. Separation and characterization of liver cells. In: Cell Separation: Methods and Selected Applications, edited by T. G. Pretlow II and T. P. Pretlow. New York: Academic, 1987, vol. 4, p. 1-24.
19. 2 actions in rat hepatocytes are mediated via different signalling pathways. Eur. J. Biochem. 218: 1083-1089, 1993.
20. Qu, W., E. Savier, and R. G. Thurman. Stimulation of monooxygenation and conjugation following liver transplantation in the rat: involvement of Kupffer cells. Mol. Pharmacol. 41: 1149-1154, 1992.
21. 2 consumption: alcohol and cell-cell communication. Am. J. Physiol. 270 (Gastrointest. Liver Physiol. 33): G574-G580, 1996.
22. 2 is oxygen-dependent in perfused rat liver. Am. J. Physiol. 275 (Gastrointest. Liver Physiol. 38): G542-G549, 1998.
23. Ratto, G. M., R. Payne, W. G. Owen, and R. Y. Tsien. The concentration of cytosolic free calcium in vertebrae rod outer segments measured with fura-2. J. Neurosci. 8: 3240-3246, 1988.
24. 2 subtype. Mol. Pharmacol. 46: 213-220, 1994.
25. Remmer, H., J. Schenkman, R. W. Estabrook, H. Sasame, J. Gillette, S. Narashimhulu, D. Y. Cooper, and O. Rosenthal. Drug interaction with hepatic microsomal cytochrome. Mol. Pharmacol. 2: 187-190, 1966.
26. Salm, A. K., and K. D. McCarthy. Norepinephrine-evoked calcium transients in cultured cerebral type I astroglia. Glia. 3: 529-538, 1990.
27. Sardanelli, A. M., Z. T. Dobrova, S. C. Scacco, F. Speranza, and S. Papa. Characterization of proteins phosphorylated by the cAMP-dependent protein kinase of bovine heart mitochondria. FEBS Lett. 377: 470-474, 1996.
28. Vegesna, R. V., and J. Diamond. Elevation of cyclic AMP by prostacyclin is accompanied by relaxation of bovine coronary arteries and contraction of rabbit aortic rings. Eur. J. Pharmacol. 128: 25-31, 1986.
29. Walsh, D. A., and D. B. Glass. Utilization of the inhibitor protein of adenosine cyclic monophosphate-dependent protein kinase, and peptides derived from it, as tools to study adenosine cyclic monophosphate-mediated cellular processes. Methods Enzymol. 201: 304-316, 1991.