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Volumn 69, Issue 4, 2006, Pages 1174-1181

Inhibition of cardiac hypertrophy by triflusal (4-trifluoromethyl derivative of salicylate) and its active metabolite

Author keywords

[No Author keywords available]

Indexed keywords

2 HYDROXY 4 (TRIFLUOROMETHYL)BENZOIC ACID; ACETYLLEUCYLLEUCYLNORLEUCINAL; ACETYLSALICYLIC ACID; ALPHA ACTININ; ATRIAL NATRIURETIC FACTOR; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; HETERODIMER; I KAPPA B KINASE ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LEUCINE; MESSENGER RNA; PHENYLEPHRINE; PROTEIN P50; PROTEINASE INHIBITOR; SALICYLIC ACID DERIVATIVE; SYNAPTOTAGMIN; UNCLASSIFIED DRUG;

EID: 33645109885     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.105.016345     Document Type: Article
Times cited : (7)

References (35)
  • 1
    • 0343081535 scopus 로고    scopus 로고
    • Oral administration of the anti-inflammatory substance triflusal results in the downregulation of constitutive transcription factor NF-kappa B in the postnatal rat brain
    • Acarin L, Gonzalez B, and Castellano B (2000) Oral administration of the anti-inflammatory substance triflusal results in the downregulation of constitutive transcription factor NF-kappa B in the postnatal rat brain. Neurosci Lett 288:41-44.
    • (2000) Neurosci Lett , vol.288 , pp. 41-44
    • Acarin, L.1    Gonzalez, B.2    Castellano, B.3
  • 2
    • 0033002191 scopus 로고    scopus 로고
    • 4-Trifluoromethyl derivatives of salicylate, triflusal and its main metabolite 2-hydroxy-4-trifluoromethylbenzoic acid, are potent inhibitors of nuclear factor kappa B activation
    • Bayon Y, Alonso A, and Crespo MS (1999) 4-Trifluoromethyl derivatives of salicylate, triflusal and its main metabolite 2-hydroxy-4-trifluoromethylbenzoic acid, are potent inhibitors of nuclear factor kappa B activation. Br J Pharmacol 126:1359-1366.
    • (1999) Br J Pharmacol , vol.126 , pp. 1359-1366
    • Bayon, Y.1    Alonso, A.2    Crespo, M.S.3
  • 3
    • 0037155907 scopus 로고    scopus 로고
    • Increased reactive oxygen species production down-regulates peroxisome proliferator-activated alpha pathway in C2C12 skeletal muscle cells
    • Cabrero A, Alegret M, Sanchez RM, Adzet T, Laguna JC, and Carrera MV (2002) Increased reactive oxygen species production down-regulates peroxisome proliferator-activated alpha pathway in C2C12 skeletal muscle cells. J Biol Chem 277:10100-10107.
    • (2002) J Biol Chem , vol.277 , pp. 10100-10107
    • Cabrero, A.1    Alegret, M.2    Sanchez, R.M.3    Adzet, T.4    Laguna, J.C.5    Carrera, M.V.6
  • 4
    • 0035432604 scopus 로고    scopus 로고
    • Bezafibrate reduces mRNA levels of adipocyte markers and increases fatty acid oxidation in primary culture of adipocytes
    • Cabrero A, Alegret M, Sanchez RM, Adzet T, Laguna JC, and Vazquez M (2001) Bezafibrate reduces mRNA levels of adipocyte markers and increases fatty acid oxidation in primary culture of adipocytes. Diabetes 50:1883-1890.
    • (2001) Diabetes , vol.50 , pp. 1883-1890
    • Cabrero, A.1    Alegret, M.2    Sanchez, R.M.3    Adzet, T.4    Laguna, J.C.5    Vazquez, M.6
  • 5
    • 17144462683 scopus 로고    scopus 로고
    • Inhibition of cyclooxygenase-2 expression by 4-trifluoromethyl derivatives of salicylate, triflusal and its deacetylated metabolite, 2-hydroxy-4-trifluoromethylbenzoic acid
    • de Arriba AF, Cavalcanti F, Miralles A, Bayon Y, Alonso A, Merlos M, Garcia-Rafanell J, and Forn J (1999) Inhibition of cyclooxygenase-2 expression by 4-trifluoromethyl derivatives of salicylate, triflusal and its deacetylated metabolite, 2-hydroxy-4-trifluoromethylbenzoic acid. Mol Pharmacol 55:753-760.
    • (1999) Mol Pharmacol , vol.55 , pp. 753-760
    • De Arriba, A.F.1    Cavalcanti, F.2    Miralles, A.3    Bayon, Y.4    Alonso, A.5    Merlos, M.6    Garcia-Rafanell, J.7    Forn, J.8
  • 7
    • 0015237263 scopus 로고
    • Indomethacin and aspirin abolish prostaglandin release from spleen
    • Ferreira SH, Moncada S, and Vane JR (1971) Indomethacin and aspirin abolish prostaglandin release from spleen. Nat New Biol 231:237-239.
    • (1971) Nat New Biol , vol.231 , pp. 237-239
    • Ferreira, S.H.1    Moncada, S.2    Vane, J.R.3
  • 10
    • 0029799831 scopus 로고    scopus 로고
    • Neuroprotection by aspirin and sodium salicylate through blockade of NF-kappa B activation
    • Grilli M, Pizzi M, Memo M, and Spano P (1996) Neuroprotection by aspirin and sodium salicylate through blockade of NF-kappa B activation. Science (Wash DC) 274:1383-1385.
    • (1996) Science (Wash DC) , vol.274 , pp. 1383-1385
    • Grilli, M.1    Pizzi, M.2    Memo, M.3    Spano, P.4
  • 12
    • 0037164814 scopus 로고    scopus 로고
    • Activation of nuclear factor-kappaB is necessary for myotrophin-induced cardiac hypertrophy
    • Gupta S, Purcell NH, Lin A, and Sen S (2002) Activation of nuclear factor-kappaB is necessary for myotrophin-induced cardiac hypertrophy. J Cell Biol 159:1019-1028.
    • (2002) J Cell Biol , vol.159 , pp. 1019-1028
    • Gupta, S.1    Purcell, N.H.2    Lin, A.3    Sen, S.4
  • 13
    • 0035126395 scopus 로고    scopus 로고
    • Effect of 4-trifluoromethyl derivatives of salicylate on nuclear factor kappa B-dependent transcription in human astrocytoma cells
    • Hernandez M, de Arriba AF, Merlos M, Fuentes L, Crespo MS, and Nieto ML (2001) Effect of 4-trifluoromethyl derivatives of salicylate on nuclear factor kappa B-dependent transcription in human astrocytoma cells. Br J Pharmacol 132:547-555.
    • (2001) Br J Pharmacol , vol.132 , pp. 547-555
    • Hernandez, M.1    De Arriba, A.F.2    Merlos, M.3    Fuentes, L.4    Crespo, M.S.5    Nieto, M.L.6
  • 15
    • 0037192342 scopus 로고    scopus 로고
    • Involvement of nuclear factor-kappa B and apoptosis signal-regulating kinase 1 in G-protein-coupled receptor agonist-induced cardiomyocyte hypertrophy
    • Hirotani S, Otsu K, Nishida K, Higuchi Y, Morita T, Nakayama H, Yamaguchi O, Mano T, Matsumura Y, Ueno H, et al. (2002) Involvement of nuclear factor-kappa B and apoptosis signal-regulating kinase 1 in G-protein-coupled receptor agonist-induced cardiomyocyte hypertrophy. Circulation 105:509-515.
    • (2002) Circulation , vol.105 , pp. 509-515
    • Hirotani, S.1    Otsu, K.2    Nishida, K.3    Higuchi, Y.4    Morita, T.5    Nakayama, H.6    Yamaguchi, O.7    Mano, T.8    Matsumura, Y.9    Ueno, H.10
  • 16
    • 0033592754 scopus 로고    scopus 로고
    • Mechanisms of disease - Signaling pathways for cardiac hypertrophy and failure
    • Hunter JJ and Chien KR (1999) Mechanisms of disease - signaling pathways for cardiac hypertrophy and failure. N Engl J Med 341:1276-1283.
    • (1999) N Engl J Med , vol.341 , pp. 1276-1283
    • Hunter, J.J.1    Chien, K.R.2
  • 18
    • 0034084163 scopus 로고    scopus 로고
    • Phosphorylation meets ubiquitination: The control of NF-kappa B activity
    • Karin M and Ben-Neriah Y (2000) Phosphorylation meets ubiquitination: the control of NF-kappa B activity. Annu Rev Immunol 18:621-663.
    • (2000) Annu Rev Immunol , vol.18 , pp. 621-663
    • Karin, M.1    Ben-Neriah, Y.2
  • 20
    • 0028167846 scopus 로고
    • Inhibition of NF-kappa-B by sodium-salicylate and aspirin
    • Kopp E and Ghosh S (1994) Inhibition of NF-kappa-B by sodium-salicylate and aspirin. Science (Wash DC) 265:956-959.
    • (1994) Science (Wash DC) , vol.265 , pp. 956-959
    • Kopp, E.1    Ghosh, S.2
  • 21
    • 0037331346 scopus 로고    scopus 로고
    • Risk of upper gastrointestinal bleeding associated with non-aspirin cardiovascular drugs, analgesics and nonsteroidal anti-inflammatory drugs
    • Lanas A, Serrano P, Bajador E, Fuentes J, and Sainz R (2003) Risk of upper gastrointestinal bleeding associated with non-aspirin cardiovascular drugs, analgesics and nonsteroidal anti-inflammatory drugs. Eur J Gastroenterol Hepatol 15:173-178.
    • (2003) Eur J Gastroenterol Hepatol , vol.15 , pp. 173-178
    • Lanas, A.1    Serrano, P.2    Bajador, E.3    Fuentes, J.4    Sainz, R.5
  • 22
    • 0025280867 scopus 로고
    • Prognostic implications of echocardiographically determined left-ventricular mass in the Framingham-Heart-Study
    • Levy D, Garrison RJ, Savage DD, Kannel WB, and Castelli WP (1990) Prognostic implications of echocardiographically determined left-ventricular mass in the Framingham-Heart-Study. N Engl J Med 322:1561-1566.
    • (1990) N Engl J Med , vol.322 , pp. 1561-1566
    • Levy, D.1    Garrison, R.J.2    Savage, D.D.3    Kannel, W.B.4    Castelli, W.P.5
  • 23
    • 0034713820 scopus 로고    scopus 로고
    • Left ventricular hypertrophy - Pathogenesis, detection and prognosis
    • Lorell BH and Carabello BA (2000) Left ventricular hypertrophy - pathogenesis, detection and prognosis. Circulation 102:470-479.
    • (2000) Circulation , vol.102 , pp. 470-479
    • Lorell, B.H.1    Carabello, B.A.2
  • 24
    • 0037385048 scopus 로고    scopus 로고
    • Comparison of triflusal and aspirin for prevention of vascular events in patients after cerebral infarction: The TACIP Study: A randomized, double-blind, multicenter trial
    • Matias-Guiu J, Ferro JM, Alvarez-Sabin J, Torres F, Jimenez MD, Lago A, and Melo T (2003) Comparison of triflusal and aspirin for prevention of vascular events in patients after cerebral infarction: the TACIP Study: a randomized, double-blind, multicenter trial. Stroke 34:840-847.
    • (2003) Stroke , vol.34 , pp. 840-847
    • Matias-Guiu, J.1    Ferro, J.M.2    Alvarez-Sabin, J.3    Torres, F.4    Jimenez, M.D.5    Lago, A.6    Melo, T.7
  • 25
    • 0031807224 scopus 로고    scopus 로고
    • Triflusal
    • McNeely W and Goa KL (1998) Triflusal. Drugs 55:823-833.
    • (1998) Drugs , vol.55 , pp. 823-833
    • McNeely, W.1    Goa, K.L.2
  • 26
    • 0032566405 scopus 로고    scopus 로고
    • Inhibitory effects of antioxidants on neonatal rat cardiac myocyte hypertrophy induced by tumor necrosis factor-α and angiotensin II
    • Nakamura K, Fushimi K, Kouchi H, Mihara K, Miyazaki M, Ohe T, and Namba M (1998) Inhibitory effects of antioxidants on neonatal rat cardiac myocyte hypertrophy induced by tumor necrosis factor-α and angiotensin II. Circulation 98:794-799.
    • (1998) Circulation , vol.98 , pp. 794-799
    • Nakamura, K.1    Fushimi, K.2    Kouchi, H.3    Mihara, K.4    Miyazaki, M.5    Ohe, T.6    Namba, M.7
  • 27
    • 0028858127 scopus 로고
    • Salicylates inhibit lipopolysaccharide-induced transcriptional activation of the tissue factor gene in human monocytic cells
    • Oeth P and Mackman N (1995) Salicylates inhibit lipopolysaccharide- induced transcriptional activation of the tissue factor gene in human monocytic cells. Blood 86:4144-4152.
    • (1995) Blood , vol.86 , pp. 4144-4152
    • Oeth, P.1    Mackman, N.2
  • 28
    • 0029870463 scopus 로고    scopus 로고
    • Salicylates inhibit I kappa B-alpha phosphorylation, endothelial- leukocyte adhesion molecule expression and neutrophil transmigration
    • Pierce JW, Read MA, Ding H, Luscinskas FW, and Collins T (1996) Salicylates inhibit I kappa B-alpha phosphorylation, endothelial-leukocyte adhesion molecule expression and neutrophil transmigration. J Immunol 156:3961-3969.
    • (1996) J Immunol , vol.156 , pp. 3961-3969
    • Pierce, J.W.1    Read, M.A.2    Ding, H.3    Luscinskas, F.W.4    Collins, T.5
  • 29
    • 0035811062 scopus 로고    scopus 로고
    • Activation of NF-kappa B is required for hypertrophic growth of primary rat neonatal ventricular cardiomyocytes
    • Purcell NH, Tang GL, Yu CF, Mercurio F, DiDonato JA, and Lin AN (2001) Activation of NF-kappa B is required for hypertrophic growth of primary rat neonatal ventricular cardiomyocytes. Proc Natl Acad Sci USA 98:6668-6673.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 6668-6673
    • Purcell, N.H.1    Tang, G.L.2    Yu, C.F.3    Mercurio, F.4    DiDonato, J.A.5    Lin, A.N.6
  • 30
    • 0034637485 scopus 로고    scopus 로고
    • Inhibitory and stimulatory effects of lactacystin on expression of nitric oxide synthase type 2 in brain glial cells: The role of IκB-β
    • Stasiolek M, Gavrilyuk V, Sharp A, Horvath P, Selmaj K, and Feinstein DL (2000) Inhibitory and stimulatory effects of lactacystin on expression of nitric oxide synthase type 2 in brain glial cells: the role of IκB-β. J Biol Chem 275:24847-24856.
    • (2000) J Biol Chem , vol.275 , pp. 24847-24856
    • Stasiolek, M.1    Gavrilyuk, V.2    Sharp, A.3    Horvath, P.4    Selmaj, K.5    Feinstein, D.L.6
  • 31
    • 0033998441 scopus 로고    scopus 로고
    • Cytoplasmic sequestration of Rel proteins by I kappa B alpha requires CRM1-dependent nuclear export
    • Tam WF, Lee LH, Davis L, and Sen R (2000) Cytoplasmic sequestration of Rel proteins by I kappa B alpha requires CRM1-dependent nuclear export. Mol Cell Biol 20:2269-2284.
    • (2000) Mol Cell Biol , vol.20 , pp. 2269-2284
    • Tam, W.F.1    Lee, L.H.2    Davis, L.3    Sen, R.4
  • 32
    • 0028982834 scopus 로고
    • Interleukin-1-beta modulates the growth and phenotype of neonatal rat cardiac myocytes
    • Thaik CM, Calderone A, Takahashi N, and Colucci WS (1995) Interleukin-1-beta modulates the growth and phenotype of neonatal rat cardiac myocytes. J Clin Investig 96:1093-1099.
    • (1995) J Clin Investig , vol.96 , pp. 1093-1099
    • Thaik, C.M.1    Calderone, A.2    Takahashi, N.3    Colucci, W.S.4
  • 33
    • 0015237292 scopus 로고
    • Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs
    • Vane JR (1971) Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. Nat New Biol 231:232-235.
    • (1971) Nat New Biol , vol.231 , pp. 232-235
    • Vane, J.R.1
  • 34
    • 0032516477 scopus 로고    scopus 로고
    • Induction of cyclooxygenase-2 and activation of nuclear factor-kappa B in myocardium of patients with congestive heart failure
    • Wong SCY, Fukuchi M, Melnyk P, Rodger I, and Giaid A (1998) Induction of cyclooxygenase-2 and activation of nuclear factor-kappa B in myocardium of patients with congestive heart failure. Circulation 98:100-103.
    • (1998) Circulation , vol.98 , pp. 100-103
    • Wong, S.C.Y.1    Fukuchi, M.2    Melnyk, P.3    Rodger, I.4    Giaid, A.5
  • 35
    • 0035797865 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma activators inhibit cardiac hypertrophy in cardiac myocytes
    • Yamamoto K, Ohki R, Lee RT, Ikeda U, and Shimada K (2001) Peroxisome proliferator-activated receptor gamma activators inhibit cardiac hypertrophy in cardiac myocytes. Circulation 104:1670-1675.
    • (2001) Circulation , vol.104 , pp. 1670-1675
    • Yamamoto, K.1    Ohki, R.2    Lee, R.T.3    Ikeda, U.4    Shimada, K.5


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