4-Trifluoromethyl derivatives of salicylate, triflusal and its main metabolite 2-hydroxy-4-trifluoromethylbenzoic acid, are potent inhibitors of nuclear factor κB activation

British Journal of Pharmacology

Volumn 126, Issue 6, 1999, Pages 1359-1366

  Bayón, Yolanda ^a   Alonso, Andrés ^a   Sánchez Crespo, Mariano ^a  

^a UNIVERSITY OF VALLADOLID   (Spain)

Author keywords

Adhesion molecules; Atherogenesis; Cyclo oxygenase; Fc receptors; Human umbilical vein endothelial cells; Immune complex; Nitric oxide; Nuclear factor B; Salicylates; Thrombosis; Triflusal

Indexed keywords

ACETYLSALICYLIC ACID; BENZOIC ACID DERIVATIVE; FC RECEPTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; NITRIC OXIDE SYNTHASE; NITRITE; SALICYLIC ACID; SALICYLIC ACID DERIVATIVE; TRIFLUSAL; TUMOR NECROSIS FACTOR ALPHA; VASCULAR CELL ADHESION MOLECULE 1;

ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; DRUG STRUCTURE; ENZYME INDUCTION; HUMAN; HUMAN CELL; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; PROTEIN TRANSPORT; STRUCTURE ACTIVITY RELATION; TRANSCRIPTION REGULATION; VASCULAR ENDOTHELIUM;

EID: 0033002191     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0702441     Document Type: Article

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