Diabetic Goto Kakizaki rats as well as type 2 diabetic patients show a decreased diurnal serum melatonin level and an increased pancreatic melatonin-receptor status

Journal of Pineal Research

Volumn 40, Issue 2, 2006, Pages 135-143

  Peschke, Elmar ^a,c   Frese, Thomas ^a   Chankiewitz, Erik ^a   Peschke, Dorothee ^a   Preiss, Uwe ^b   Schneyer, Ulrich ^c   Spessert, Rainer ^d   Mühlbauer, Eckhard ^e  

^a Inst of Anatomy and Cell Biology   (Germany)

^b Children's Hospital   (United States)

^c MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^d JOHANNES GUTENBERG UNIVERSITY   (Germany)

^e Saxon Academy of Sciences   (Germany)

Author keywords

Arylalkylamine N acetyltransferase; Beta cell; Diabetes; Insulin receptor; Melatonin receptor; Pineal

Indexed keywords

ARALKYLAMINE ACETYLTRANSFERASE; GLUCOSE; INSULIN; INSULIN RECEPTOR; MELATONIN; MELATONIN RECEPTOR; MESSENGER RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CIRCADIAN RHYTHM; CONTROLLED STUDY; ENZYME ACTIVITY; HORMONE BLOOD LEVEL; HUMAN; HUMAN TISSUE; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; NUCLEOTIDE SEQUENCE; PANCREAS ISLET BETA CELL; PINEAL GLAND FUNCTION; PROTEIN EXPRESSION; RADIOIMMUNOASSAY; RAT; RAT STRAIN; REAL TIME POLYMERASE CHAIN REACTION; RECEPTOR UPREGULATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; ARYLALKYLAMINE N-ACETYLTRANSFERASE; CIRCADIAN RHYTHM; DIABETES MELLITUS, TYPE 2; HUMANS; INSULIN; MALE; MELATONIN; PANCREAS; PINEAL GLAND; RATS; RATS, WISTAR; RECEPTOR, INSULIN; RECEPTORS, MELATONIN;

EID: 33645100557     PISSN: 07423098     EISSN: 1600079X     Source Type: Journal    
DOI: 10.1111/j.1600-079X.2005.00287.x     Document Type: Article

References (51)

1. D iaz B B lázquez E Effect of pinealectomy on plasma glucose, insulin and glucagon levels in the rat Horm Metab Res 1986 18 225 229
2. R odriguez V M ellado C A lvarez E de D iego JG B lázquez E Effect of pinealectomy on liver insulin and glucagon receptor concentrations in the rat J Pineal Res 1989 6 77 88
3. M ellado C R odriguez V de D iego JG A lvarez E B lázquez E Effect of pinealectomy and of diabetes on liver insulin and glucagon receptor concentrations in the rat J Pineal Res 1989 6 295 306
4. B enson B M iller CW S orrentino S Effects of blinding on blood glucose and serum insulin-like activity in rats Texas Rep Biol Med 1971 29 513 525
5. C saba G B arath P Are Langerhans's islets influenced by the pineal body Experientia 1971 27 962
6. C saba G N agy SU The regulatory role of the pineal gland on the thyroid gland adrenal medulla and the islets of Langerhans Acta Biol Med Ger 1973 31 617 619
7. G orray KC Q uay WB E wart RBL Effects of pinealectomy and pineal incubation medium and sonicates on insulin release by isolated pancreatic islets in vitro Horm Metab Res 1979 11 432 436
8. Q uay WB G orray KC Pineal effects on metabolism and glucose homeostasis: evidence for lines of humoral mediation of pineal influences on tumor growth J Neural Transm 1980 47 107 120
9. B oden G R uiz J U rbain JL C hen X Evidence for a circadian rhythm of insulin secretion Am J Physiol 1996 271 E246 E252
10. R asmussen DD B oldt BM W ilkinson CW et al. Daily melatonin administration at middle age suppresses male rat visceral fat plasma leptin and plasma insulin to youthful levels Endocrinology 1999 140 1009 1012
11. W olden -H anson T M itton DR M c C ants RL et al. Daily melatonin administration to middle-aged male rats suppresses body weight, intraabdominal adiposity and plasma leptin and insulin independent of food intake and total body fat Endocrinology 2000 141 487 497
12. C agnacci A A rangino S R enzi A et al. Influence of melatonin administration on glucose tolerance and insulin sensitivity of postmenopausal women Clin Endocrinol (Oxf) 2001 54 339 346
13. F eldman JM L ebovitz HE Structural determinants of indole amine action on in vitro insulin release Endocrinology 1972 91 809 816
14. F rankel BJ S trandberg MJ Insulin release from isolated mouse islets in vitro: no effect of physiological levels of melatonin or arginine vasotocin J Pineal Res 1991 11 145 148
15. B izot -E spiard JG D ouble A C ousin B et al. Lack of melatonin effects on insulin action in normal rats Horm Metab Res 1998 30 711 716
16. N ishida S S ato R M urai I et al. Effect of pinealectomy on plasma levels of insulin and leptin and on hepatic lipids in type 2 diabetic rats J Pineal Res 2003 35 251 256
17. N ishida S S egawa T M urai I et al. Long-term melatonin administration reduces hyperinsulinemia and improves the altered fatty-acid compositions in type 2 diabetic rats via the restoration of Delta-5 desaturase activity J Pineal Res 2002 32 26 33
18. L ynch HJ E ng JP W urtman RJ Control of pineal indole biosynthesis by changes in sympathetic tone caused by factors other than environmental lighting Proc Natl Acad Sci USA 1973 70 1704 1707
19. N amboodiri MAA F avilla JT K lein DC Pineal N-acetyltransferase is inactivated by disulfide-containing peptides: insulin is the most potent Science 1981 213 571 573
20. C hampney TH B rainard GC R ichardson BA et al. Experimentally induced diabetes reduces nocturnal pineal melatonin content in the Syrian hamster Comp Biochem Physiol 1983 76A 199 201
21. C hampney TH H oltorf AP C raft CM et al. Hormonal modulation of pineal melatonin synthesis in rats and Syrian hamsters: effects of streptozotocin- induced diabetes and insulin injections Comp Biochem Physiol 1986 83A 391 395
22. O'B rien IA L ewin IG O'H are JP et al. Abnormal circadian rhythm of melatonin in diabetic autonomic neuropathy Clin Endocrinol (Oxf) 1986 24 359 364
23. P eschke E P eschke D H ammer T et al. Influence of melatonin and serotonin on glucose-stimulated insulin release from perifused rat pancreatic islets in vitro J Pineal Res 1997 23 156 163
24. P eschke E F auteck JD M usshoff U et al. Evidence for a melatonin receptor within pancreatic islets of neonate rats: functional autoradiographic and molecular investigations J Pineal Res 2000 28 156 164
25. 1) mediated influence of melatonin on cAMP concentration and insulin secretion of rat insulinoma cells INS-1 J Pineal Res 2002 33 63 71
26. G oto Y K akizaki M The spontaneous-diabetes rat: a model of noninsulin dependent diabetes mellitus Proc Jpn Acad Ser B Phys Biol Sci 1981 57 381 384
27. Z ong -C hao L E fendic S W ibom R et al. Glucose metabolism in Goto-Kakizaki rat islets Endocrinology 1998 139 2670 2675
28. T reskes M A driaansen HJ van der L eur SJ et al. Multicentre evaluation of the EBIO plus glucose analyser Eur J Clin Chem Clin Biochem 1996 34 777 784
29. M ühlbauer E W olgast S F inckh U et al. Indication of circadian oscillations in the rat pancreas FEBS Lett 2004 564 91 96
30. E ngel L V ollrath L S pessert R Arylalkylamine N-acetyltransferase gene expression in retina and pineal gland of rats under various photoperiods Biochem Biophys Res Commun 2004 318 983 986
31. L aybutt DR G landt M X u G et al. Critical reduction in beta-cell mass results in two distinct outcomes over time. Adaptions with impaired glucose tolerance or decompensated diabetes J Biol Chem 2003 278 2997 3005
32. S chmittgen TD Z akrajsek BA M ills AG et al. Quantitative reverse transcription-polymerase chain reaction to study mRNA decay: comparison of endpoint and real-time methods Anal Biochem 2000 285 194 204
33. P faffl MW H organ GW D empfle L Relative expression software tool (REST) for group-wise comparison and statistical analysis of relative expression results in real-time PCR Nucleic Acids Res 2002 30 1 10
34. D amiola F L e M inh N P reitner N et al. Restricted feeding uncouples circadian oscillators in peripheral tissues from the central pacemaker in the suprachiasmatic nucleus Genes Dev 2000 14 2950 2961
35. D eguchi T A xelrod J Sensitive assay for serotonin N-acetyltransferase activity in rat pineal Anal Biochem 1972 50 174 179
36. K emp DM U beda M H abener JF Identification and functional characterization of melatonin Mel 1a receptors in pancreatic b cells: potential role in incretin-mediated cell function by sensitization of cAMP signaling Mol Cell Endocrinol 2002 191 157 166
37. von G all C S tehle JH W eaver DR Mammalian melatonin receptors: molecular biology and signal transduction Cell Tissue Res 2002 309 151 162
38. S chuster C G auer F M alan A et al. The circadian clock, light/dark cycle and melatonin are differentially involved in the expression of daily and photoperiodic variations in mt(1) melatonin receptors in the Siberian and Syrian hamsters Neuroendocrinology 2001 74 55 68
39. N eu JM N iles LP A marked diurnal rhythm of melatonin ML1A receptor mRNA expression in the suprachiasmatic nucleus Brain Res Mol Brain Res 1997 49 303 306
40. V anecek J Cellular mechanisms of melatonin action Physiol Rev 1998 78 687 721
41. R oka F B rydon L W aldhoer M et al. Tight association of the human Mel(1a)-melatonin receptor and G(i): precoupling and constitutive activity Mol Pharmacol 1999 56 1014 1024
42. von G all C L ewy A S chomerus C et al. Transcription factor dynamics and neuroendocrine signalling in the mouse pineal gland: a comparative analysis of melatonin-deficient C57BL mice and melatonin-proficient C3H mice Eur J Neurosci 2000 12 964 972
43. L iu T B orjigin J N-acetyltransferase is not the rate-limiting enzyme of melatonin synthesis at night J Pineal Res 2005 39 91 96
44. Z heng W S chwarzer D L ebeau A et al. Cellular stability of serotonin N-acetyltransferase conferred by phosphonodifluoromethylene alanine (Pfa) substitution for Ser-205 J Biol Chem 2005 280 10462 10467
45. G anguly S W eller JL H o A et al. Melatonin synthesis: 14-3-3-dependent activation and inhibition of arylalkylamine N-acetyltransferase mediated by phosphoserine-205 Proc Natl Acad Sci USA 2005 102 1222 1227
46. N amboodiri MAA F avilla JT K lein DC Activation of pineal acetyl coenzyme A hydroxylase by disulphide peptides J Biol Chem 1982 257 1030 1032
47. P icinato MC H aber EP C ipolla -N eto J et al. Melatonin inhibits insulin secretion and decreases PKA levels without interfering with glucose metabolism in rat pancreatic islets J Pineal Res 2002 33 156 160
48. C utando A G omez -M oreno G V illalba J et al. Relationship between salivary melatonin levels and peridontal status in diabetic patients J Pineal Res 2003 35 239 244
49. T utuncu NB B atur MK Y ildirir A et al. Melatonin levels decrease in type 2 diabetic patients with cardiac autonomic neuropathy J Pineal Res 2005 39 43 49
50. P icinato MC H aber EP C arpinelli AR et al. Daily rhythm of glucose-induced insulin secretion by isolated islets from intact and pinealectomized rat J Pineal Res 2002 33 172 177
51. P eschke E P eschke D Evidence for a circadian rhythm of insulin release from perifused rat pancreatic islets Diabetologia 1998 41 1085 1092