Core of the partner switching signalling mechanism is conserved in the obligate intracellular pathogen Chlamydia trachomatis

Molecular Microbiology

Volumn 59, Issue 2, 2006, Pages 623-636

  Hua, Lei ^a,c   Hefty, P Scott ^b   Lee, Young Jin ^a   Lee, Young Moo ^a   Stephens, Richard S ^b   Price, Chester W ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; ASPARTIC ACID; BACTERIAL PROTEIN; MUTANT PROTEIN; RSB1 PROTEIN; RSB2 PROTEIN; SERINE; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL MEMBRANE; BACTERIAL VIRULENCE; CHLAMYDIA TRACHOMATIS; CONTROLLED STUDY; GENE TARGETING; GENETIC CODE; GENOME; HYBRID; IMMUNE RESPONSE; NONHUMAN; PARALOGY; PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN INTERACTION; TANDEM MASS SPECTROMETRY; YEAST;

AMINO ACID SEQUENCE; BACTERIAL PROTEINS; BASE SEQUENCE; CARRIER PROTEINS; CHLAMYDIA TRACHOMATIS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DNA PRIMERS; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; PHOSPHORYLATION; SEQUENCE HOMOLOGY, AMINO ACID; SIGNAL TRANSDUCTION; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TRANSCRIPTION, GENETIC; TWO-HYBRID SYSTEM TECHNIQUES;

BACTERIA (MICROORGANISMS); CHLAMYDIA TRACHOMATIS;

EID: 33645062674     PISSN: 0950382X     EISSN: 13652958     Source Type: Journal    
DOI: 10.1111/j.1365-2958.2005.04962.x     Document Type: Article

References (69)

1. Adler E. Donella-Deana A. Arigoni F. Pinna LA. Stragler P. 1997 Structural relationship between a bacterial developmental protein and eukaryotic PP2C protein phosphatases Mol Microbiol 23 57 62
2. B of Bacillus subtilis J Bacteriol 183 1329 1338
3. Alper S. Dufour A. Garsin DA. Duncan L. Losick R. 1996 Role of adenosine nucleotides in the regulation of a stress-response transcription factor in Bacillus subtilis J Mol Biol 260 165 177
4. Altschul SF. Madden TL. Schaffer AA. Zhang J. Zhang Z. Miller W. Lipman DJ. 1997 Gapped blast and psi - blast: a new generation of protein database search programs Nucleic Acids Res 25 3389 3402
5. Aravind L. Koonin EV. 2000 The STAS domain - a link between anion transporters and anti σ-factor antagonists Curr Biol 10 R53 R55
6. Aravind L. Ponting CP. 1999 The cytoplasmic helical linker domain of receptor histidine kinase and methyl-accepting proteins is common to many prokaryotic signaling proteins FEMS Microbiol Lett 176 111 116
7. F activity by distinct mechanisms Mol Microbiol 45 1527 1540
8. Belland RJ. Zhong G. Crane DD. Hogan D. Sturdevant D. Sharma J. et al. 2003 Genomic transcriptional profiling of the developmental cycle of Chlamydia trachomatis Proc Natl Acad Sci USA 100 8478 8483
9. B is regulated by a binding protein (RsbW) that blocks its association with core RNA polymerase Proc Natl Acad Sci USA 90 2330 2334
10. Claros MG. von Heijne G. 1994 TopPred II: an improved software for membrane protein structure predictions Comput Appl Biosci 10 685 686
11. Clifton DR. Fields KA. Grieshaber SS. Dooley CA. Fischer ER. Mead DJ. et al. 2004 A chlamydial type III translocated protein is tyrosine-phosphorylated at the site of entry and associated with recruitment of actin Proc Natl Acad Sci USA 101 10166 10171
12. Das AK. Helps NR. Cohen PT. Barford D. 1996 Crystal structure of the protein serine/threonine phosphatase 2C at 2.0 Å resolution EMBO J 15 6798 6809
13. Delumeau O. Dutta S. Brigulla M. Kuhnke G. Hardwick SW. Volker U. et al. 2004 Functional and structural characterization of RsbU, a stress signaling protein phosphatase 2C J Biol Chem 279 40927 40937
14. F of Bacillus subtilis Genes Dev 8 2653 2663
15. Douglas AL. Hatch TP. 2000 Expression of the transcripts of the sigma factors and putative sigma factor regulators of Chlamydia trachomatis L2 Gene 247 209 214
16. Dufour A. Haldenwang WG. 1994 Interactions between a Bacillus subtilis anti-σ factor (RsbW) and its antagonist (RsbV) J Bacteriol 176 1813 1820
17. F from Bacillus subtilis Proc Natl Acad Sci USA 90 2325 2329
18. Dutta R. Inouye M. 2000 GHKL, an emergent ATPase/kinase superfamily Trends Biochem Sci 25 24 28
19. Eng JK. McCormack AL. Yates JR., 3rd 1994 An approach to correlate tandem mass spectral data of peptides with amino acid sequences in a protein database J Am Soc Mass Spectom 5 976 989
20. Fields KA. Hackstadt T. 2002 The chlamydial inclusion: escape from the endocytic pathway Annu Rev Cell Dev Biol 18 221 245
21. Fields KA. Mead DJ. Dooley CA. Hackstadt T. 2003 Chlamydia trachomatis type III secretion: evidence for a functional apparatus during early-cycle development Mol Microbiol 48 671 683
22. Fields S. Song O. 1989 A novel genetic system to detect protein-protein interactions Nature 340 245 246
23. Gatlin CL. Kleemann GR. Hays LG. Link AJ. Yates JR., 3rd 1998 Protein identification at the low femtomole level from silver-stained gels using a new fritless electrospray interface for liquid chromatography-microspray and nanospray mass spectrometry Anal Biochem 263 93 101
24. Gruber TM. Gross CA. 2003 Multiple sigma subunits and the partitioning of bacterial transcription space Annu Rev Microbiol 57 441 466
25. Hilbert DW. Piggot PJ. 2004 Compartmentalization of gene expression during Bacillus subtilis spore formation Microbiol Mol Biol Rev 68 234 262
26. Ho SN. Hunt HD. Horton RM. Pullen JK. Pease LR. 1989 Site-directed mutagenesis by overlap extension using the polymerase chain reaction Gene 77 51 59
27. Jackson MD. Fjeld CC. Denu JM. 2003 Probing the function of conserved residues in the serine/threonine phosphatase PP2Cα Biochemistry 42 8513 8521
28. B in response to environmental stress J Bacteriol 178 3846 3853
29. Kang CM. Vijay K. Price CW. 1998 Serine kinase activity of a Bacillus subtilis switch protein is required to transduce environmental stress signals but not to activate its target PP2C phosphatase Mol Microbiol 30 189 196
30. Kim TJ. Gaidenko TA. Price CW. 2004 A multicomponent protein complex mediates environmental stress signaling in Bacillus subtilis J Mol Biol 341 135 150
31. 43 J Biol Chem 265 13206 13214
32. Koo IC. Stephens RS. 2003 A developmentally regulated two-component signal transduction system in Chlamydia J Biol Chem 278 17314 17319
33. Koonin EV. Avarind L. Galperin MY. 2000 A comparative-genomic view of the microbial stress response. In Bacterial Stress Responses Storz G. Hengge-Aronis R. (eds) Washington, DC American Society for Microbiology Press, pp. 417 444
34. Kozak NA. Mattoo S. Foreman-Wykert AK. Whitelegge JP. Miller JF. 2005 Interactions between partner switcher orthologs BtrW and BtrV regulate type III secretion in Bordetella J Bacteriol 187 5665 5676
35. B by an anti- and an anti-anti-sigma factor in Streptomyces coelicolor in response to osmotic stress J Bacteriol 186 8490 8498
36. T method Methods 25 402 408
37. Mamoun CB. Sullivan DJ. Banerjee R. Goldberg DE. 1998 Identification and characterization of an unusual double serine/threonine protein phosphatase 2C in the malaria parasite Plasmodium falciparum J Biol Chem 273 11241 11247
38. Marchler-Bauer A. Bryant SH. 2004 CD-Search: protein domain annotations on the fly Nucleic Acids Res 32 W327 W331
39. Mattoo S. Yuk MH. Huang LL. Miller JF. 2004 Regulation of type III secretion in Bordetella Mol Microbiol 52 1201 1214
40. Miller JH. 1972 Experiments in Molecular Genetics Cold Spring Harbor, NY Cold Spring Harbor Laboratory Press
41. F, the first compartment-specific transcription factor of B. subtilis, is regulated by an anti-σ factor that is also a protein kinase Cell 74 735 742
42. B of Bacillus subtilis and its regulatory proteins J Mol Microbiol Biotechnol 4 427 452
43. Moulder JW. 1991 Interaction of chlamydiae and host cells in vitro Microbiol Rev 55 143 190
44. F of Bacillus subtilis J Bacteriol 177 2912 2913
45. Nicholson TL. Olinger L. Chong K. Schoolnik G. Stephens RS. 2003 Global stage-specific gene regulation during the developmental cycle of Chlamydia trachomatis J Bacteriol 185 3179 3189
46. Peng J. Elias JE. Thoreen CC. Licklider LJ. Gygi SP. 2003 Evaluation of multidimensional chromatography coupled with tandem mass spectrometry (LC/LC-MS/MS) for large-scale protein analysis: the yeast proteome J Proteome Res 2 43 50
47. 70 proteins in T4-type phages and bacteria that are similar to AsiA, a transcription inhibitor and co-activator of bacteriophage T4 J Mol Biol 344 1183 1197
48. Price CW. 2002 General stress response. In Bacillus subtilis and Its Closest Relatives: From Genes to Cells Sonenshein AL. Hoch JA. Losick R. (eds) Washington, DC American Society for Microbiology Press, pp. 369 384
49. Pullen KE. Ng HL. Sung PY. Good MC. Smith SM. Alber T. 2004 An alternate conformation and a third metal in PstP/Ppp, the M. tuberculosis PP2C-family Ser/Thr protein phosphatase Structure (Camb) 12 1947 1954
50. Rau A. Wyllie S. Whittimore J. Raulston JE. 2005 Identification of Chlamydia trachomatis genomic sequences recognized by chlamydial divalent cation-dependent regulator A (DcrA) J Bacteriol 187 443 448
51. Rockey DD. Scidmore MA. Bannantine JP. Brown WJ. 2002 Proteins in the chlamydial inclusion membrane Microbes Infect 4 333 340
52. Salcedo SP. Holden DW. 2005 Bacterial interactions with the eukaryotic secretory pathway Curr Opin Microbiol 8 92 98
53. Sambrook J. Fritsch EF. Maniatis T. 1989 Molecular Cloning: A Laboratory Manual Cold Spring Harbor, NY Cold Spring Harbor Laboratory Press
54. Schaumburg CS. Tan M. 2003 Mutational analysis of the Chlamydia trachomatis dnaK promoter defines the optimal -35 promoter element Nucleic Acids Res 31 551 555
55. Schracter J. 1999 Infection and disease epidemiology. In Chlamydia: Intracellular Biology, Pathogenesis, and Immunity Stephens RS. (ed.). Washington, DC American Society for Microbiology, pp. 139 169
56. Schroeter R. Schlisio S. Lucet I. Yudkin M. Borriss R. 1999 The Bacillus subtilis regulator protein SpoIIE shares functional and structural similarities with eukaryotic protein phosphatases 2C FEMS Microbiol Lett 174 117 123
57. Shaw EI. Dooley CA. Fischer ER. Scidmore MA. Fields KA. Hackstadt T. 2000 Three temporal classes of gene expression during the Chlamydia trachomatis developmental cycle Mol Microbiol 37 913 925
58. 28 recognizes the fliC promoter of Escherichia coli and responds to heat shock in chlamydiae Microbiology 150 205 215
59. Stephens RS. Kalman S. Lammel C. Fan J. Marathe R. Aravind L. et al. 1998 Genome sequence of an obligate intracellular pathogen of humans: Chlamydia trachomatis Science 282 754 759
60. Subtil A. Delevoye C. Balana ME. Tastevin L. Perrinet S. Dautry-Varsat A. 2005 A directed screen for chlamydial proteins secreted by a type III mechanism identifies a translocated protein and numerous other new candidates Mol Microbiol 56 1636 1647
61. Thompson JD. Higgins DG. Gibson TJ. 1994 clustal w: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice Nucleic Acids Res 22 4673 4680
62. B transcription factor of Bacillus subtilis Mol Microbiol 35 180 188
63. B antagonist, RsbV, by stress- or starvation-induced phosphatase activities J Bacteriol 178 5456 5463
64. B regulators J Bacteriol 178 7020 7023
65. Wilson AC. Tan M. 2004 Stress response gene regulation in Chlamydia is dependent on HrcA-CIRCE interactions J Bacteriol 186 3384 3391
66. Yang X. Kang CM. Brody MS. Price CW. 1996 Opposing pairs of serine protein kinases and phosphatases transmit signals of environmental stress to activate a bacterial transcription factor Genes Dev 10 2265 2275
67. 28 RNA polymerase regulates hctB, a late developmental gene in Chlamydia Mol Microbiol 50 577 584
68. Yuk MH. Harvill ET. Cotter PA. Miller JF. 2000 Modulation of host immune responses, induction of apoptosis and inhibition of NF-κB activation by the Bordetella type III secretion system Mol Microbiol 35 991 1004
69. Zhong G. Fan P. Ji H. Dong F. Huang Y. 2001 Identification of a chlamydial protease-like activity factor responsible for the degradation of host transcription factors J Exp Med 193 935 942