Probing the function of conserved residues in the serine/threonine phosphatase PP2Cα

Biochemistry

Volumn 42, Issue 28, 2003, Pages 8513-8521

  Jackson, Michael D ^a   Fjeld, Clark C ^a   Denu, John M ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CATALYSIS; CHEMICAL BONDS; ENZYMES; IONIZATION; IONS; PH EFFECTS; SUBSTRATES;

MUTANTS;

BIOCHEMISTRY;

CARBOXYLIC ACID DERIVATIVE; PHOSPHOPROTEIN PHOSPHATASE; PHOSPHOPROTEIN PHOSPHATASE 2CALPHA; PHOSPHOSERINE; PHOSPHOTHREONINE; PROTEIN SERINE THREONINE KINASE; SERINE THREONINE PHOSPHATASE; UNCLASSIFIED DRUG;

ARTICLE; BRONSTED ANALYSIS; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME ANALYSIS; ENZYME KINETICS; IONIZATION; POINT MUTATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTON TRANSPORT; SITE DIRECTED MUTAGENESIS; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; CONSERVED SEQUENCE; HUMANS; HYDROGEN-ION CONCENTRATION; KINETICS; LIGANDS; MUTAGENESIS, SITE-DIRECTED; PHOSPHOPROTEIN PHOSPHATASE; PROTEIN CONFORMATION; RECOMBINANT PROTEINS;

EID: 0037779029     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi034074+     Document Type: Article

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