메뉴 건너뛰기




Volumn 76, Issue 3, 2006, Pages 230-236

Mutational and methylation analysis of the cyclin-dependent kinase 4 inhibitor (p16INK4A) gene in chronic lymphocytic leukemia

Author keywords

Chronic lymphocytic leukemia; Deletion; Methylation specific polymerase chain reaction; Mutation; p16 INK4A gene; Promoter methylation

Indexed keywords

PROTEIN P16INK4A; RESTRICTION ENDONUCLEASE;

EID: 33645057939     PISSN: 09024441     EISSN: 16000609     Source Type: Journal    
DOI: 10.1111/j.1600-0609.2005.00604.x     Document Type: Article
Times cited : (18)

References (44)
  • 1
    • 0033567907 scopus 로고    scopus 로고
    • Unmutated immunoglobulin VH genes are associated with a more aggressive form of chronic lymphocytic leukaemia
    • H amblin TJ D avis Z G ardiner A O scier DG S tevenson FK Unmutated immunoglobulin VH genes are associated with a more aggressive form of chronic lymphocytic leukaemia Blood 1999 94 1848 1854
    • (1999) Blood , vol.94 , pp. 1848-1854
    • Hamblin, T.J.1    Davis, Z.2    Gardiner, A.3    Oscier, D.G.4    Stevenson, F.K.5
  • 2
    • 0032980308 scopus 로고    scopus 로고
    • The prognostic significance of altered cyclin dependent kinase inhibitors in human cancer
    • T sihlias J K apusta L S lingerland J The prognostic significance of altered cyclin dependent kinase inhibitors in human cancer Ann Rev Med 1999 50 401 423
    • (1999) Ann Rev Med , vol.50 , pp. 401-423
    • Tsihlias, J.1    Kapusta, L.2    Slingerland, J.3
  • 4
    • 0028275733 scopus 로고
    • Deletions of the cyclin dependent kinase-4 inhibitor gene in multiple cancers
    • N obori T M iura K W u DJ L ois A T akabayashi K C arson DA Deletions of the cyclin dependent kinase-4 inhibitor gene in multiple cancers Nature 1994 368 753 756
    • (1994) Nature , vol.368 , pp. 753-756
    • Nobori, T.1    Miura, K.2    Wu, D.J.3    Lois, A.4    Takabayashi, K.5    Carson, D.A.6
  • 5
    • 0029134016 scopus 로고
    • Role of the cyclin-dependent kinase inhibitors in the development of cancer
    • H irama T K oeffler P Role of the cyclin-dependent kinase inhibitors in the development of cancer Blood 1995 86 841 854
    • (1995) Blood , vol.86 , pp. 841-854
    • Hirama, T.1    Koeffler, P.2
  • 7
    • 0028935143 scopus 로고
    • Detection of CDKN2 deletions in tumor cell lines and primary glioma by interphase fluorescence in situ hybridisation
    • D reyling MH B ohlander SK A deyanju MO O lopade OI Detection of CDKN2 deletions in tumor cell lines and primary glioma by interphase fluorescence in situ hybridisation Cancer Res 1995 55 984 988
    • (1995) Cancer Res , vol.55 , pp. 984-988
    • Dreyling, M.H.1    Bohlander, S.K.2    Adeyanju, M.O.3    Olopade, O.I.4
  • 10
    • 9444276546 scopus 로고    scopus 로고
    • Prevalence of germ-line mutations in p16, p19ARF, and CDK4 in familial melanoma: Analysis of a clinic-based population
    • F itz -G erald MG H arkin DP S ilva -A rrieta S et al. Prevalence of germ-line mutations in p16, p19ARF, and CDK4 in familial melanoma: analysis of a clinic-based population Proc Natl Acad Sci 1996 93 8541 8545
    • (1996) Proc Natl Acad Sci , vol.93 , pp. 8541-8545
    • Fitz-Gerald, M.G.1    Harkin, D.P.2    Silva-Arrieta, S.3
  • 11
    • 0031860559 scopus 로고    scopus 로고
    • Review of alterations of the cyclin-dependent kinase inhibitor INK4 family genes p15, p16, p18 and p19 in human leukaemia-lymphoma cells
    • D rexler HG Review of alterations of the cyclin-dependent kinase inhibitor INK4 family genes p15, p16, p18 and p19 in human leukaemia-lymphoma cells Leukemia 1998 12 845 859
    • (1998) Leukemia , vol.12 , pp. 845-859
    • Drexler, H.G.1
  • 12
    • 0027938776 scopus 로고
    • Candidate tumor-suppressor genes MTS1 (p16INK4A) and MTS2 (p15INK4B) display frequent homozygous deletions in primary cells from T-but not from B-cell lineage acute lymphoblastic leukemias
    • H ebert J C ayuela JM B erkeley J S igaux F Candidate tumor-suppressor genes MTS1 (p16INK4A) and MTS2 (p15INK4B) display frequent homozygous deletions in primary cells from T-but not from B-cell lineage acute lymphoblastic leukemias Blood 1994 84 4038 4044
    • (1994) Blood , vol.84 , pp. 4038-4044
    • Hebert, J.1    Cayuela, J.M.2    Berkeley, J.3    Sigaux, F.4
  • 14
    • 0031035406 scopus 로고    scopus 로고
    • Frequent and selective methylation of p15 and deletion of both p15 and p16 in T-cell acute lymphoblastic leukemia
    • B atova A D icciani MB V u T Y u JC B ridgeman L Y u AL Frequent and selective methylation of p15 and deletion of both p15 and p16 in T-cell acute lymphoblastic leukemia Cancer Res 1997 57 832 836
    • (1997) Cancer Res , vol.57 , pp. 832-836
    • Batova, A.1    Dicciani, M.B.2    Vu, T.3    Yu, J.C.4    Bridgeman, L.5    Yu, A.L.6
  • 15
    • 0344717631 scopus 로고    scopus 로고
    • P16 gene alterations in mantle cell lymphoma
    • C ohen PL J ames CD K urtin PJ p16 gene alterations in mantle cell lymphoma Blood 1997 90 491a
    • (1997) Blood , vol.90
    • Cohen, P.L.1    James, C.D.2    Kurtin, P.J.3
  • 16
    • 0031025368 scopus 로고    scopus 로고
    • Distinct patterns of inactivation of p15INK4B and p16INK4A characterize major types of hematological malignancies
    • H erman JG C ivin CI I ssa JPJ C ollector MI S harkis SJ B aylin SB Distinct patterns of inactivation of p15INK4B and p16INK4A characterize major types of hematological malignancies Cancer Res 1997 57 837 841
    • (1997) Cancer Res , vol.57 , pp. 837-841
    • Herman, J.G.1    Civin, C.I.2    Issa, J.P.J.3    Collector, M.I.4    Sharkis, S.J.5    Baylin, S.B.6
  • 19
    • 0030726251 scopus 로고    scopus 로고
    • De novo methylation of tumor suppressor genes CDKN2A and CDKN2B is a rare finding in B-cell chronic lymphocytic leukemia
    • M artel V G uerci A H umbert JC G regoire MJ C hery M L ederlin P J onveaux P De novo methylation of tumor suppressor genes CDKN2A and CDKN2B is a rare finding in B-cell chronic lymphocytic leukemia Br J Hematol 1997 99 320 324
    • (1997) Br J Hematol , vol.99 , pp. 320-324
    • Martel, V.1    Guerci, A.2    Humbert, J.C.3    Gregoire, M.J.4    Chery, M.5    Lederlin, P.6    Jonveaux, P.7
  • 20
    • 0033199104 scopus 로고    scopus 로고
    • Frequent methylation silencing of p15 INK4a and p16 INK4b in B-cell and T-cell Lymphomas
    • B aur AS S haw BP B urri N D elacretaz F B osman FT C haubert P Frequent methylation silencing of p15 INK4a and p16 INK4b in B-cell and T-cell Lymphomas Blood 1999 94 1773 1781
    • (1999) Blood , vol.94 , pp. 1773-1781
    • Baur, A.S.1    Shaw, B.P.2    Burri, N.3    Delacretaz, F.4    Bosman, F.T.5    Chaubert, P.6
  • 24
    • 0024756969 scopus 로고
    • Rapid and sensitive detection of point mutation and polymorphisms using polymerase chain reaction
    • O rita M S uzuki Y S ekiya T H ayashi K Rapid and sensitive detection of point mutation and polymorphisms using polymerase chain reaction Genomics 1989 5 874 879
    • (1989) Genomics , vol.5 , pp. 874-879
    • Orita, M.1    Suzuki, Y.2    Sekiya, T.3    Hayashi, K.4
  • 27
    • 0026337295 scopus 로고
    • Tumor suppressor gene
    • W einberg RA Tumor suppressor gene Science 1991 254 1138 1146
    • (1991) Science , vol.254 , pp. 1138-1146
    • Weinberg, R.A.1
  • 29
    • 0021879645 scopus 로고
    • Hereditary cancer, oncogenes, and antioncogenes
    • K nudson JAG Hereditary cancer, oncogenes, and antioncogenes Cancer Res 1985 45 1437 1443
    • (1985) Cancer Res , vol.45 , pp. 1437-1443
    • Knudson, J.A.G.1
  • 30
    • 0035890321 scopus 로고    scopus 로고
    • Haplo-insufficiency? Let me count the ways
    • Q uon KC B erns A Haplo-insufficiency? Let me count the ways Genes Dev 2001 15 2915 2921
    • (2001) Genes Dev , vol.15 , pp. 2915-2921
    • Quon, K.C.1    Berns, A.2
  • 31
    • 0032511848 scopus 로고    scopus 로고
    • The murine gene p27Kip1 is haplo-insufficient for tumor-suppression
    • F ero ML R andel E G urley KE R oberts JM K emp CJ The murine gene p27Kip1 is haplo-insufficient for tumor-suppression Nature 1998 396 177 180
    • (1998) Nature , vol.396 , pp. 177-180
    • Fero, M.L.1    Randel, E.2    Gurley, K.E.3    Roberts, J.M.4    Kemp, C.J.5
  • 33
    • 0030687951 scopus 로고    scopus 로고
    • Deletions and rearrangements of cyclin-dependent kinase 4 inhibitor gene p16 are associated with poor prognosis in B cell non-Hodgkin's lymphomas
    • G arcia -S anz R G onzalez M V argas M C hillon MC B alanzategui A B arbon M F lores MT S an Miguel JF Deletions and rearrangements of cyclin-dependent kinase 4 inhibitor gene p16 are associated with poor prognosis in B cell non-Hodgkin's lymphomas Leukemia 1997 11 1915 1920
    • (1997) Leukemia , vol.11 , pp. 1915-1920
    • Garcia-Sanz, R.1    Gonzalez, M.2    Vargas, M.3    Chillon, M.C.4    Balanzategui, A.5    Barbon, M.6    Flores, M.T.7    San Miguel, J.F.8
  • 37
  • 38
    • 0034160333 scopus 로고    scopus 로고
    • Biology of chronic lymphocytic leukemia
    • C aligaris -C appio F Biology of chronic lymphocytic leukemia Rev Clin Exp Hematol 2000 4 5 21
    • (2000) Rev Clin Exp Hematol , vol.4 , pp. 5-21
    • Caligaris-Cappio, F.1
  • 39
    • 0345357773 scopus 로고    scopus 로고
    • Gene silencing in cancer in association with promoter hypermethylation
    • H erman JG B aylin SB Gene silencing in cancer in association with promoter hypermethylation N Engl J Med 2003 349 2042 2054
    • (2003) N Engl J Med , vol.349 , pp. 2042-2054
    • Herman, J.G.1    Baylin, S.B.2
  • 42
    • 0034654269 scopus 로고    scopus 로고
    • Aberrant p15 promoter methylation in adult and childhood acute leukemias of nearly all morphologic subtypes: Potential prognostic implications
    • W ong IH N g MH H uang DP L ee JC Aberrant p15 promoter methylation in adult and childhood acute leukemias of nearly all morphologic subtypes: potential prognostic implications Blood 2000 95 1942 1949
    • (2000) Blood , vol.95 , pp. 1942-1949
    • Wong, I.H.1    Ng, M.H.2    Huang, D.P.3    Lee, J.C.4
  • 44
    • 0037108309 scopus 로고    scopus 로고
    • Demethylation of a hypermethylated p15/INK4B gene in patients with myelodysplastic syndromes by 5-Aza-2′-deoxycytidine (decitabine) treatment
    • D askalakis M N guyen TT N guyen C G uldberg P K ohler G W ijermans P J ones PA L ubbert M Demethylation of a hypermethylated p15/INK4B gene in patients with myelodysplastic syndromes by 5-Aza-2′-deoxycytidine (decitabine) treatment Blood 2002 100 2957 2964
    • (2002) Blood , vol.100 , pp. 2957-2964
    • Daskalakis, M.1    Nguyen, T.T.2    Nguyen, C.3    Guldberg, P.4    Kohler, G.5    Wijermans, P.6    Jones, P.A.7    Lubbert, M.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.