Variability and failure of neurotransmission in the diaphragm of mdx mice

Neuromuscular Disorders

Volumn 16, Issue 3, 2006, Pages 168-177

  Personius, Kirkwood E ^a   Sawyer, Robert P ^a  

^a UNIVERSITY AT BUFFALO   (United States)

Author keywords

Dystrophin; mdx Mouse; Neuromuscular junction; Neurotransmission failure

Indexed keywords

CHOLINERGIC RECEPTOR;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIAPHRAGM; IMMUNOHISTOCHEMISTRY; MOUSE; MUSCLE CONTRACTILITY; MUSCLE CONTRACTION; MUSCLE EXCITATION; MUSCLE FATIGUE; MUSCLE FORCE; MUSCULAR DYSTROPHY; MYOPATHY; NERVE STIMULATION; NEUROTRANSMISSION; NONHUMAN; PHRENIC NERVE; PRIORITY JOURNAL;

ANIMALS; BUNGAROTOXINS; DIAPHRAGM; DOSE-RESPONSE RELATIONSHIP, RADIATION; ELECTRIC STIMULATION; IMMUNOHISTOCHEMISTRY; MICE; MICE, INBRED C57BL; MICE, INBRED MDX; MUSCLE CONTRACTION; PHRENIC NERVE; RECEPTORS, CHOLINERGIC; SYNAPTIC TRANSMISSION;

EID: 33644979210     PISSN: 09608966     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nmd.2006.01.002     Document Type: Article

References (36)

1. E. Bonilla, C.E. Samitt, and A.F. Miranda Duchenne muscular dystrophy: deficiency of dystrophin at the muscle cell surface Cell 54 1988 447 452
2. E.P. Hoffman, R.H. Brown Jr, and L.M. Kunkel Dystrophin: the protein product of the Duchenne muscular dystrophy locus Cell 51 1987 919 928
3. G.B. Banks, C. Fuhrer, M.E. Adams, and S.C. Froehner The postsynaptic submembrane machinery at the neuromuscular junction: requirement for rapsyn and the utrophin/dystrophin-associated complex J Neurocytol 32 2003 709 726
4. B.J. Petrof Molecular pathophysiology of myofiber injury in deficiencies of the dystrophin-glycoprotein complex Am J Phys Med Rehabil 81 2002 S162 S174
5. H.H. Stedman, H.L. Sweeney, and J.B. Shrager The mdx mouse diaphragm reproduces the degenerative changes of Duchenne muscular dystrophy Nature 352 1991 536 539
6. A. Nagel, F. Lehmann-Horn, and A.G. Engel Neuromuscular transmission in the mdx mouse Muscle Nerve 13 1990 742 749
7. R.M. Grady, H. Zhou, J.M. Cunningham, M.D. Henry, K.P. Campbell, and J.R. Sanes Maturation and maintenance of the neuromuscular synapse: genetic evidence for roles of the dystrophin-glycoprotein complex Neuron 25 2000 279 293
8. R.M. Grady, M. Akaaboune, A.L. Cohen, M.M. Maimone, J.W. Lichtman, and J.R. Sanes Tyrosine-phosphorylated and nonphosphorylated isoforms of alpha-dystrobrevin: roles in skeletal muscle and its neuromuscular and myotendinous junctions J Cell Biol 160 2003 741 752
9. A.E. Deconinck, A.C. Potter, and J.M. Tinsley Postsynaptic abnormalities at the neuromuscular junctions of utrophin-deficient mice J Cell Biol 136 1997 883 894
10. A.E. Deconinck, J.A. Rafael, and J.A. Skinner Utrophin-dystrophin- deficient mice as a model for Duchenne muscular dystrophy Cell 90 1997 717 727
11. R.M. Grady, H. Teng, M.C. Nichol, J.C. Cunningham, R.S. Wilkinson, and J.R. Sanes Skeletal and cardiac myopathies in mice lacking utrophin and dystrophin: a model for Duchenne muscular dystrophy Cell 90 1997 729 738
12. P.R. Lyons, and C.R. Slater Structure and function of the neuromuscular junction in young adult mdx mice J Neurocytol 20 1991 969 981
13. K. Personius, and R. Sawyer Terminal Schwann cell structure is altered in the diaphragm of mdx mice Muscle Nerve 32 2005 656 663
14. E.C. Pereira, H.S. Neto, and M.J. Marques Immunolocalisation of neuronal nitric oxide synthase at the neuromuscular junction of MDX mice: a confocal microscopy study J Anat 198 2001 663 671
15. F. Jerusalem, A.G. Engel, and M.R. Gomez Duchenne dystrophy. II. Morphometric study of motor end-plate fine structure Brain 97 1974 123 130
16. J. Kong, and J.E. Anderson Dystrophin is required for organizing large acetylcholine receptor aggregates Brain Res 839 1999 298 304
17. K. Kitaoka, Y. Matsuda, J. Desaki, S. Oki, Y. Nagano, and T. Shibata Topographic comparison of subneural apparatuses at neuromuscular junctions in normal and dystrophic (mdx) mice: a scanning electron microscope study J Electron Microsc Tokyo 46 1997 193 197
18. L.F. Torres, and L.W. Duchen The mutant mdx: inherited myopathy in the mouse. Morphological studies of nerves, muscles and end-plates Brain 110 Pt 2 1987 269 299
19. R. Xu, and M.M. Salpeter Acetylcholine receptors in innervated muscles of dystrophic mdx mice degrade as after denervation J Neurosci 17 1997 8194 8200
20. C.G. Carlson, and D.M. Roshek Adult dystrophic (mdx) endplates exhibit reduced quantal size and enhanced quantal variation Pflugers Arch 442 2001 369 375
21. J.H. Kuei, R. Shadmehr, and G.C. Sieck Relative contribution of neurotransmission failure to diaphragm fatigue J Appl Physiol 68 1990 174 180
22. K.E. Personius, J. Nautiyal, and S. Reddy Myotonia and muscle contractile properties in mice with SIX5 deficiency Muscle Nerve 31 2005 503 505
23. J.S. Clancy, H. Takeshima, S.L. Hamilton, and M.B. Reid Contractile function is unaltered in diaphragm from mice lacking calcium release channel isoform 3 Am J Physiol 277 1999 R1205 R1209
24. W.Z. Zhan, J.F. Watchko, Y.S. Prakash, and G.C. Sieck Isotonic contractile and fatigue properties of developing rat diaphragm muscle J Appl Physiol 84 1998 1260 1268
25. T.K. Aldrich, A. Shander, I. Chaudhry, and H. Nagashima Fatigue of isolated rat diaphragm: role of impaired neuromuscular transmission J Appl Physiol 61 1986 1077 1083
26. M.M. Lowery, N.S. Stoykov, and T.A. Kuiken Independence of myoelectric control signals examined using a surface EMG model IEEE Trans Biomed Eng 50 2003 789 793
27. K.E. Personius, and R.J. Balice-Gordon Loss of correlated motor neuron activity during synaptic competition at developing neuromuscular synapses Neuron 31 2001 395 408
28. E.E. Dupont-Versteegden, and R.J. McCarter Differential expression of muscular dystrophy in diaphragm versus hindlimb muscles of mdx mice Muscle Nerve 15 1992 1105 1110
29. B.J. Petrof, J.B. Shrager, H.H. Stedman, A.M. Kelly, and H.L. Sweeney Dystrophin protects the sarcolemma from stresses developed during muscle contraction Proc Natl Acad Sci USA 90 1993 3710 3714
30. C.G. Carlson The dystrophinopathies: an alternative to the structural hypothesis Neurobiol Dis 5 1998 3 15
31. B.J. Petrof, H.H. Stedman, J.B. Shrager, J. Eby, H.L. Sweeney, and A.M. Kelly Adaptations in myosin heavy chain expression and contractile function in dystrophic mouse diaphragm Am J Physiol 265 1993 C834 C841
32. S.S. Segal, J.A. Faulkner, and T.P. White Skeletal muscle fatigue in vitro is temperature dependent J Appl Physiol 61 1986 660 665
33. M.J. Titmus, and D.S. Faber Axotomy-induced alterations in the electrophysiological characteristics of neurons Prog Neurobiol 35 1990 1 51
34. C.G. Carlson Acetylcholine receptor and calcium leakage activity in nondystrophic and dystrophic myotubes (MDX) Muscle Nerve 19 1996 1258 1267
35. C.G. Carlson, and T. Officer Single channel evidence for a cytoskeletal defect involving acetylcholine receptors and calcium influx in cultured dystrophic (mdx) myotubes Muscle Nerve 19 1996 1116 1126
36. C.G. Carlson, A. Gueorguiev, D.M. Roshek, R. Ashmore, J.S. Chu, and J.E. Anderson Extrajunctional resting Ca2+ influx is not increased in a severely dystrophic expiratory muscle (triangularis sterni) of the mdx mouse Neurobiol Dis 14 2003 229 239