Adult dystrophic (mdx) endplates exhibit reduced quantal size and enhanced quantal variation

Pflugers Archiv European Journal of Physiology

Volumn 442, Issue 3, 2001, Pages 369-375

  Carlson, C George ^a   Roshek, Diana M ^a  

^a A T STILL UNIVERSITY   (United States)

Author keywords

Acetylcholine receptors; mdx Mouse; Miniature endplate potential; Muscular dystrophy; Neuromuscular junction; Quantal amplitude

Indexed keywords

CHOLINERGIC RECEPTOR;

ANIMAL TISSUE; ARTICLE; CONDUCTANCE; CONTROLLED STUDY; MINIATURE ENDPLATE POTENTIAL; MOUSE; MUSCULAR DYSTROPHY; NERVE ENDING; NEUROMUSCULAR SYNAPSE; NEUROTRANSMISSION; NONHUMAN; POSTSYNAPTIC POTENTIAL; PRIORITY JOURNAL;

AGE FACTORS; ANIMALS; DIAPHRAGM; MEMBRANE POTENTIALS; MICE; MICE, INBRED MDX; MOTOR ENDPLATE; MUSCLE FIBERS; MUSCULAR DYSTROPHY, ANIMAL; NEUROMUSCULAR JUNCTION; RECEPTORS, CHOLINERGIC;

EID: 0034956422     PISSN: 00316768     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004240100561     Document Type: Article

References (27)

1. Nitric oxide synthase complexed with dystrophin and absent from skeletal muscle sarcolemma in Duchenne muscular dystrophy
2. Early postnatal changes in presynaptic potassium sensitivity
3. Acetylcholine receptor and calcium leakage activity in nondystrophic and dystrophic myotubes (mdx)
4. The dystrophinopathies: An alternative to the structural hypothesis
5. Spontaneous changes in acetylcholine receptor and calcium leakage activity in cell-attached patches from cultured dystrophic myotubes
6. A baseline detection method for analyzing transient electrophysiological events
7. Single channel evidence for a cytoskeletal defect involving acetylcholine receptors and calcium influx in cultured dystrophic (mdx) myotubes
8. The effect of temperature on the amplitude distributions of miniature endplate potentials in the mouse diaphragm
9. Neuronal nitric oxide synthase and dystrophin-deficient muscular dystrophy
10. Quantal components of the endplate potential
11. Skeletal and cardiac myopathies in mice lacking utrophin and dystrophin: A model for Duchenne muscular dystrophy
12. Role for α-dystrobrevin in the pathogenesis of dystrophin-dependent muscular dystrophies
13. Sarcoglycans in muscular dystrophy
14. Topographic comparison of subneural apparatuses at neuromuscular junctions in normal and dystrophic (mdx) mice: A scanning electron microscope study
15. Dystrophin is required for organizing large acetylcholine receptor aggregates
16. Spontaneous release of transmitter substance in multiquantal units
17. A voltage-clamp study of the permeability change induced by quanta of transmitter at the mouse end-plate
18. Structure and function of the neuromuscular junction in young adult mdx mice
19. Changes in MEPP and EPP amplitude distributions in the mouse diaphragm during synapse formation and degeneration
20. Neuromuscular transmission in the mdx mouse
21. Dystrophin-associated proteins are greatly reduced in skeletal muscle from mdx mice
22. Differential membrane localization and intermolecular associations of α-dystrobrevin isoforms in skeletal muscle
23. Perturbation in dystrophin-associated glycoprotein complex in a boy with Becker muscular dystrophy
24. Skeletal muscle pathology in X chromosome-linked muscular dystrophy (mdx) mouse
25. The mutant mdx: Inherited myopathy in the mouse
26. Acetylcholine receptors in innervated muscles of dystrophic mdx mice degrade as after denervation