Dystrophin is required for organizing large acetylcholine receptor aggregates

Brain Research

Volumn 839, Issue 2, 1999, Pages 298-304

  Kong, Jiming ^a   Anderson, Judy E ^a  

^a UNIVERSITY OF MANITOBA   (Canada)

Author keywords

Acetylcholine receptor; Agrin; Dystrophin; Muscle regeneration; Neuromuscular junction; Satellite cell

Indexed keywords

AGRIN; CHOLINERGIC RECEPTOR; DYSTROPHIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CAPPING PHENOMENON; CONTROLLED STUDY; DUCHENNE MUSCULAR DYSTROPHY; MOUSE; MUSCLE REGENERATION; MYOTUBE; NERVE ENDING; NEUROMUSCULAR SYNAPSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; SATELLITE CELL;

AGE FACTORS; AGRIN; ANIMALS; ANTIBODIES, MONOCLONAL; CHO CELLS; CRICETINAE; DYSTROPHIN; GENE EXPRESSION; MICE; MICE, INBRED C57BL; MICE, INBRED MDX; MUSCLE FIBERS; MUSCLE, SKELETAL; MUSCULAR DYSTROPHY, ANIMAL; NEUROMUSCULAR JUNCTION; RECEPTORS, CHOLINERGIC; REGENERATION; TRANSFECTION;

EID: 0033612935     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(99)01737-0     Document Type: Article

References (28)

1. Allen R.E., Temm-Grove C.J., Sheehan S.M., Rice G. Skeletal muscle satellite cell cultures. Methods Cell Biol. 52:1998;155-176.
2. Anderson J.E., Ovalle W.K., Bressler B.H. Electron microscopic and autoradiographic characterization of hindlimb muscle regeneration in the mdx mouse. Anat. Rec. 219:1987;249-257.
3. S.C. Brown, J.A. Lucy, Dystrophin: Gene, Protein and Cell Biology. Cambridge Univ. Press, Cambridge, 1997.
4. Bezakova G., Bloch R.J. The zinc finger domain of the 43-kDa receptor-associated protein, rapsyn: role in acetylcholine receptor clustering. Mol. Cell. Neurosci. 11:1998;274-288.
5. Blake D.J., Tinsley J.M., Davies K.E. Utrophin: a structural and functional comparison to dystrophin. Brain Pathol. 6:1996;37-47.
6. Carlson C.G. Acetylcholine receptor and calcium leakage activity in nondystrophic and dystrophic myotubes (mdx). Muscle Nerve. 19:1996;1258-1267.
7. Carlson C.G. The dystrophinopathies: An alternative to the structural hypothesis. Neurobiol. Dis. 5:1998;3-15.
8. Deconinck A.E., Potter A.C., Tinsley J.M., Wood S.J., Vater R., Young C., Metzinger L., Vincent A., Slater C.R., Davies K.E. Postsynaptic abnormalities at the neuromuscular junctions of utrophin-deficient mice. J. Cell Biol. 136:1997;883-894.
9. Deconinck A.E., Rafael J.A., Skinner J.A., Brown S.C., Potter A.C., Metzinger L., Watt D.J., Dickson J.G., Tinsley J.M., Davies K.E. Utrophin-dystrophin-deficient mice as a model for Duchenne muscular dystrophy. Cell. 90:1997;717-727.
10. Desaki J., Uehara Y. Formation and maturation of subneural apparatuses at neuromuscular junctions in postnatal rats: a scanning and transmission electron microscopical study. Dev. Biol. 119:1987;390-401.
11. Dmytrenko G.M., Pumplin D.W., Bloch R.J. Dystrophin in a membrane skeletal network: localization and comparison to other proteins. J. Neurosci. 13:1993;547-558.
12. Grady R.M., Merlie J.P., Sanes J.R. Subtle neuromuscular defects in utrophin-deficient mice. J. Cell Biol. 136:1997;871-882.
13. Grady R.M., Teng H., Nichol M.C., Cunningham J.C., Wilkinson R.S., Sanes J.R. Skeletal and cardiac myopathies in mice lacking utrophin and dystrophin: a model for Duchenne muscular dystrophy. Cell. 90:1997;729-738.
14. Huard J., Fortier L.P., Dansereau G., Labrecque C., Tremblay J.P. A light and electron microscopic study of dystrophin localization at the mouse neuromuscular junction. Synapse. 10:1992;83-93.
15. Kitaoka K., Matsuda Y., Desaki J., Oki S., Nagano Y., Shibata T. Topographic comparison of subneural apparatuses at neuromuscular junctions in normal and dystrophic (mdx) mice: a scanning electron microscope study. J. Electron Microsc. (Tokyo). 46:1997;193-197.
16. Koenig M., Monaco A.P., Kunkel L.M. The complete sequence of dystrophin predicts a rod-shaped cytoskeletal protein. Cell. 53:1988;219-228.
17. Lyons P.R., Slater C.R. Structure and function of the neuromuscular junction in young adult mdx mice. J. Neurocytol. 20:1991;969-981.
18. Ramarao M.K., Cohen J.B. Mechanism of nicotinic acetylcholine receptor cluster formation by rapsyn. Proc. Natl. Acad. Sci. U.S.A. 95:1998;4007-4012.
19. McIntosh L.M., Garrett K.L., Megeney L., Rudnicki M.A., Anderson J.E. Regeneration and myogenic cell proliferation correlate with taurine levels in dystrophin- and MyoD-deficient muscles. Anat. Rec. 252:1998;311-324.
20. Ohlendieck K., Campbell K.P. Dystrophin-associated proteins are greatly reduced in skeletal muscle from mdx mice. J. Cell Biol. 115:1991;1685-1694.
21. Pons F., Robert A., Marini J.F., Léger J.J. Does utrophin expression in muscles of mdx mice during postnatal development functionally compensate for dystrophin deficiency? J. Neurol. Sci. 122:1994;162-170.
22. Porter G.A., Dmytrenko G.M., Winkelmann J.C., Bloch R.J. Dystrophin colocalizes with beta-spectrin in distinct subsarcolemmal domains in mammalian skeletal muscle. J. Cell Biol. 117:1992;997-1005.
23. Salpeter M.M., Marchaterre M., Harris R. Distribution of extrajunctional acetylcholine receptors on a vertebrate muscle: evaluated by using scanning microscope autoradiographic procedure. J. Cell Biol. 106:1988;2087-2093.
24. Sandrock A.W. Jr., Dryer S.E., Rosen K.M., Gozani S.N., Kramer R., Theill L.E., Fischbach G.D. Maintenance of acetylcholine receptor number by neuregulins at the neuromuscular junction in vivo. Science. 276:1997;599-603.
25. Sanes J.R., Lichtman J.W. Development of the vertebrate neuromuscular junction. Annu. Rev. Neurosci. 22:1999;389-442.
26. Sealock R., Butler M.H., Kramarcy N.R., Gao K.X., Murnane A.A., Douville K., Froehner S.C. Localization of dystrophin relative to acetylcholine receptor domains in electric tissue and adult and cultured skeletal muscle. J. Cell Biol. 113:1991;1133-1144.
27. Torres L.F., Duchen L.W. The mutant mdx: inherited myopathy in the mouse Morphological studies of nerves muscles and end-plates. Brain. 110:1987;269-299.
28. Xu R., Salpeter M.M. Acetylcholine receptors in innervated muscles of dystrophic mdx mice degrade as after denervation. J. Neurosci. 17:1997;8194-8200.