메뉴 건너뛰기




Volumn 43, Issue 11, 2006, Pages 1846-1854

The usage of alternative splice sites in mus musculus synaptotagmin-like 2 gene is modulated by cyclosporin A and FK506 in T-lymphocytes

Author keywords

Gene transcription; Immunosuppressive agents; Messengers RNA; RNA Splicing; T Lymphocytes

Indexed keywords

CALCINEURIN; CYCLOSPORIN A; MESSENGER RNA; SYNAPTOTAGMIN; TSUKUBAENOLIDE;

EID: 33644942694     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2005.10.019     Document Type: Article
Times cited : (4)

References (48)
  • 1
    • 0027370186 scopus 로고
    • FKBP-rapamycin inhibits a cyclin-dependent kinase activity and a cyclin D1-Cdk association in early G1 of an osteosarcoma cell line
    • M.W. Albers, R.T. Williams, E.J. Brown, A. Tanaka, F.L. Hall, and S.L. Schreiber FKBP-rapamycin inhibits a cyclin-dependent kinase activity and a cyclin D1-Cdk association in early G1 of an osteosarcoma cell line J. Biol. Chem. 268 1993 22825 22829
    • (1993) J. Biol. Chem. , vol.268 , pp. 22825-22829
    • Albers, M.W.1    Williams, R.T.2    Brown, E.J.3    Tanaka, A.4    Hall, F.L.5    Schreiber, S.L.6
  • 2
    • 0036534129 scopus 로고    scopus 로고
    • Alternative splicing: Multiple control mechanisms and involvement in human disease
    • J.F. Caceres, and A.R. Kornblihtt Alternative splicing: multiple control mechanisms and involvement in human disease Trends Genet. 18 2002 186 193
    • (2002) Trends Genet. , vol.18 , pp. 186-193
    • Caceres, J.F.1    Kornblihtt, A.R.2
  • 3
    • 0036207384 scopus 로고    scopus 로고
    • Listening to silence and understanding nonsense: Exonic mutations that affect splicing
    • L. Cartegni, S.L. Chew, and A.R. Krainer Listening to silence and understanding nonsense: exonic mutations that affect splicing Nat. Rev. Genet. 3 2002 285 298
    • (2002) Nat. Rev. Genet. , vol.3 , pp. 285-298
    • Cartegni, L.1    Chew, S.L.2    Krainer, A.R.3
  • 4
    • 0347365798 scopus 로고    scopus 로고
    • Cyclosporin a induces proliferation in human gingival fibroblasts via induction of transforming growth factor-beta1
    • P. Cotrim, H. Martelli-Junior, E. Graner, J.J. Sauk, and R.D. Coletta Cyclosporin A induces proliferation in human gingival fibroblasts via induction of transforming growth factor-beta1 J. Periodontol. 74 2003 1625 1633
    • (2003) J. Periodontol. , vol.74 , pp. 1625-1633
    • Cotrim, P.1    Martelli-Junior, H.2    Graner, E.3    Sauk, J.J.4    Coletta, R.D.5
  • 5
    • 0033525748 scopus 로고    scopus 로고
    • 2+, calcineurin, and NF-AT
    • 2+, calcineurin, and NF-AT Cell 96 1999 611 614
    • (1999) Cell , vol.96 , pp. 611-614
    • Crabtree, G.R.1
  • 6
    • 0024833664 scopus 로고
    • Cyclosporin-A specifically inhibits function of nuclear proteins involved in T-cell activation
    • E.A. Emmel, C.L. Verweij, D.B. Durand, K.M. Higgins, E. Lacy, and G.R. Crabtree Cyclosporin-A specifically inhibits function of nuclear proteins involved in T-cell activation Science 246 1989 1617 1620
    • (1989) Science , vol.246 , pp. 1617-1620
    • Emmel, E.A.1    Verweij, C.L.2    Durand, D.B.3    Higgins, K.M.4    Lacy, E.5    Crabtree, G.R.6
  • 7
    • 0028276439 scopus 로고
    • Immunophilins in protein folding and immunosuppression
    • D.A. Fruman, S.J. Burakoff, and B.E. Bierer Immunophilins in protein folding and immunosuppression FASEB J. 8 1994 391 400
    • (1994) FASEB J. , vol.8 , pp. 391-400
    • Fruman, D.A.1    Burakoff, S.J.2    Bierer, B.E.3
  • 8
    • 0026503434 scopus 로고
    • Calcineurin phosphatase activity in lymphocytes-T is inhibited by FK-506 and Cyclosporin-A
    • D.A. Fruman, C.B. Klee, B.E. Bierer, and S.J. Burakoff Calcineurin phosphatase activity in lymphocytes-T is inhibited by FK-506 and Cyclosporin-A Proc. Natl. Acad. Sci. U.S.A 89 1992 3686 3690
    • (1992) Proc. Natl. Acad. Sci. U.S.A , vol.89 , pp. 3686-3690
    • Fruman, D.A.1    Klee, C.B.2    Bierer, B.E.3    Burakoff, S.J.4
  • 9
    • 0029372979 scopus 로고
    • The superfamily of arginine/serine-rich splicing factors
    • X.D. Fu The superfamily of arginine/serine-rich splicing factors RNA 1 1995 663 680
    • (1995) RNA , vol.1 , pp. 663-680
    • Fu, X.D.1
  • 10
    • 0034805325 scopus 로고    scopus 로고
    • Synaptotagmin-like protein 1-3: A novel family of C-terminal-type tandem C2 proteins
    • M. Fukuda, and K. Mikoshiba Synaptotagmin-like protein 1-3: a novel family of C-terminal-type tandem C2 proteins Biochem. Biophys. Res. Commun. 281 2001 1226 1233
    • (2001) Biochem. Biophys. Res. Commun. , vol.281 , pp. 1226-1233
    • Fukuda, M.1    Mikoshiba, K.2
  • 11
    • 0034815867 scopus 로고    scopus 로고
    • Novel splicing isoforms of synaptotagmin-like proteins 2 and 3: Identification of the Slp homology domain
    • M. Fukuda, C. Saegusa, and Mikoshiba K Novel splicing isoforms of synaptotagmin-like proteins 2 and 3: identification of the Slp homology domain Biochem. Biophys. Res. Commun. 283 2001 513 519
    • (2001) Biochem. Biophys. Res. Commun. , vol.283 , pp. 513-519
    • Fukuda, M.1    Saegusa, C.2    Mikoshiba, K.3
  • 13
    • 0033835333 scopus 로고    scopus 로고
    • Sorting out the complexity of SR protein functions
    • B.R. Graveley Sorting out the complexity of SR protein functions RNA 6 2000 1197 1211
    • (2000) RNA , vol.6 , pp. 1197-1211
    • Graveley, B.R.1
  • 14
    • 0036470544 scopus 로고    scopus 로고
    • A cyclophilin functions in pre-mRNA splicing
    • D.S. Horowitz, E.J. Lee, S.A. Mabon, and T. Misteli A cyclophilin functions in pre-mRNA splicing EMBO J. 21 2002 470 480
    • (2002) EMBO J. , vol.21 , pp. 470-480
    • Horowitz, D.S.1    Lee, E.J.2    Mabon, S.A.3    Misteli, T.4
  • 15
    • 0026527505 scopus 로고
    • Rao A. Analysis of the AP-1 sites in the IL-2 promoter
    • J. Jain, and V.E. Valge-Archer Rao A. Analysis of the AP-1 sites in the IL-2 promoter J. Immunol. 148 1992 1240 1250
    • (1992) J. Immunol. , vol.148 , pp. 1240-1250
    • Jain, J.1    Valge-Archer, V.E.2
  • 16
    • 0042671357 scopus 로고    scopus 로고
    • Pre-mRNA splicing: Awash in a sea of proteins
    • M.S. Jurica, and M.J. Moore Pre-mRNA splicing: awash in a sea of proteins Mol. Cell 12 2003 5 14
    • (2003) Mol. Cell , vol.12 , pp. 5-14
    • Jurica, M.S.1    Moore, M.J.2
  • 17
    • 0028207526 scopus 로고
    • Regulation of new DNA synthesis in mammalian cells by cyclosporine. Demonstration of a transforming growth factor beta-dependent mechanism of inhibition of cell growth
    • A. Khanna, B. Li, K.H. Stenzel, and M. Suthanthiran Regulation of new DNA synthesis in mammalian cells by cyclosporine. Demonstration of a transforming growth factor beta-dependent mechanism of inhibition of cell growth Transplantation 57 1994 577 582
    • (1994) Transplantation , vol.57 , pp. 577-582
    • Khanna, A.1    Li, B.2    Stenzel, K.H.3    Suthanthiran, M.4
  • 18
    • 0033698581 scopus 로고    scopus 로고
    • Manipulating immune responses with immunosuppressive agents that target NFAT
    • A. Kiani, A. Rao, and J. Aramburu Manipulating immune responses with immunosuppressive agents that target NFAT Immunity 12 2000 359 372
    • (2000) Immunity , vol.12 , pp. 359-372
    • Kiani, A.1    Rao, A.2    Aramburu, J.3
  • 20
    • 10344266449 scopus 로고    scopus 로고
    • Rab27A-binding protein Slp2-a is required for peripheral melanosome distribution and elongated cell shape in melanocytes
    • T.S. Kuroda, and M. Fukuda Rab27A-binding protein Slp2-a is required for peripheral melanosome distribution and elongated cell shape in melanocytes Nat. Cell Biol. 6 2004 1195 1203
    • (2004) Nat. Cell Biol. , vol.6 , pp. 1195-1203
    • Kuroda, T.S.1    Fukuda, M.2
  • 21
    • 0035158730 scopus 로고    scopus 로고
    • A mechanism for exon skipping caused by nonsense or missense mutations in BRCA1 and other genes
    • H.X. Liu, L. Cartegni, M.Q. Zhang, and A.R. Krainer A mechanism for exon skipping caused by nonsense or missense mutations in BRCA1 and other genes Nat. Genet. 27 2001 55 58
    • (2001) Nat. Genet. , vol.27 , pp. 55-58
    • Liu, H.X.1    Cartegni, L.2    Zhang, M.Q.3    Krainer, A.R.4
  • 22
    • 0025893168 scopus 로고
    • Calcineurin is a common target of cyclophilin-cyclosporin-A and FKBP-FK506 complexes
    • J. Liu, J.D. Farmer, W.S. Lane, J. Friedman, I. Weissman, and S.L. Schreiber Calcineurin is a common target of cyclophilin-cyclosporin-A and FKBP-FK506 complexes Cell 66 1991 807 815
    • (1991) Cell , vol.66 , pp. 807-815
    • Liu, J.1    Farmer, J.D.2    Lane, W.S.3    Friedman, J.4    Weissman, I.5    Schreiber, S.L.6
  • 23
    • 1642293891 scopus 로고    scopus 로고
    • Characterization of a gene encoding two isoforms of a mitochondrial protein up-regulated by cyclosporin a in activated T cells
    • L. Mascarell, R. Auger, A. Alcover, D.M. Ojcius, T. Jungas, and V. Cadet-Daniel Characterization of a gene encoding two isoforms of a mitochondrial protein up-regulated by cyclosporin a in activated T cells J. Biol. Chem. 279 2004 10556 10563
    • (2004) J. Biol. Chem. , vol.279 , pp. 10556-10563
    • Mascarell, L.1    Auger, R.2    Alcover, A.3    Ojcius, D.M.4    Jungas, T.5    Cadet-Daniel, V.6
  • 24
    • 0034721074 scopus 로고    scopus 로고
    • Increased protein synthesis after T cell activation in presence of cyclosporin a
    • L. Mascarell, H. Frey, F. Michel, I. Lefkovits, and P. Truffa-Bachi Increased protein synthesis after T cell activation in presence of cyclosporin A Transplantation 70 2000 340 348
    • (2000) Transplantation , vol.70 , pp. 340-348
    • Mascarell, L.1    Frey, H.2    Michel, F.3    Lefkovits, I.4    Truffa-Bachi, P.5
  • 25
    • 0036829076 scopus 로고    scopus 로고
    • Cyclosporin a therapy differently affects immunological-relevant gene expression following immunization
    • L. Mascarell, and P. Truffa-Bachi Cyclosporin A therapy differently affects immunological-relevant gene expression following immunization Immunol. Lett. 14 2002 137 143
    • (2002) Immunol. Lett. , vol.14 , pp. 137-143
    • Mascarell, L.1    Truffa-Bachi, P.2
  • 26
    • 0038362300 scopus 로고    scopus 로고
    • New aspects of cyclosporin a mode of action: From gene silencing to gene up-regulation
    • L. Mascarell, and P. Truffa-Bachi New aspects of cyclosporin A mode of action: from gene silencing to gene up-regulation Mini Rev. Med. Chem. 3 2003 207 216
    • (2003) Mini Rev. Med. Chem. , vol.3 , pp. 207-216
    • Mascarell, L.1    Truffa-Bachi, P.2
  • 27
    • 0028264022 scopus 로고
    • X-ray structure of a cyclophilin B cyclosporin complex: Comparison with cyclophilin a and delineation of its calcineurin-binding domain
    • V. Mikol, J. Kallen, and M.D. Walkinshaw X-ray structure of a cyclophilin B cyclosporin complex: comparison with cyclophilin A and delineation of its calcineurin-binding domain Proc. Natl. Acad. Sci. U.S.A. 91 1994 5183 5186
    • (1994) Proc. Natl. Acad. Sci. U.S.A. , vol.91 , pp. 5183-5186
    • Mikol, V.1    Kallen, J.2    Walkinshaw, M.D.3
  • 28
    • 0036337915 scopus 로고    scopus 로고
    • A genomic view of alternative splicing
    • B. Modrek, and C. Lee A genomic view of alternative splicing Nat. Genet. 30 2002 13 19
    • (2002) Nat. Genet. , vol.30 , pp. 13-19
    • Modrek, B.1    Lee, C.2
  • 29
    • 0035393343 scopus 로고    scopus 로고
    • Genome-wide detection of alternative splicing in expressed sequences of human genes
    • B. Modrek, A. Resch, C. Grasso, and C. Lee Genome-wide detection of alternative splicing in expressed sequences of human genes Nucleic Acids Res. 29 2001 2850 2859
    • (2001) Nucleic Acids Res. , vol.29 , pp. 2850-2859
    • Modrek, B.1    Resch, A.2    Grasso, C.3    Lee, C.4
  • 30
    • 0033427727 scopus 로고    scopus 로고
    • Regulation of gingival fibroblast interleukin-6 secretion by cyclosporine a
    • R.S. Morton, and A.I. Dongari-Bagtzoglou Regulation of gingival fibroblast interleukin-6 secretion by cyclosporine A J. Periodontol. 70 1999 1464 1471
    • (1999) J. Periodontol. , vol.70 , pp. 1464-1471
    • Morton, R.S.1    Dongari-Bagtzoglou, A.I.2
  • 31
    • 0344198459 scopus 로고    scopus 로고
    • The spliceosome: The most complex macromolecular machine in the cell?
    • T.W. Nilsen The spliceosome: the most complex macromolecular machine in the cell? Bioessays 25 2003 1147 1149
    • (2003) Bioessays , vol.25 , pp. 1147-1149
    • Nilsen, T.W.1
  • 32
    • 0034194042 scopus 로고    scopus 로고
    • Potentiation of CD3-induced expression of the linker for activation of T cells (LAT) by the calcineurin inhibitors cyclosporin a and FK506
    • D. Peters, M. Tsuchida, E.R. Manthei, T. Alam, C.S. Cho, and S.J. Knechtle Potentiation of CD3-induced expression of the linker for activation of T cells (LAT) by the calcineurin inhibitors cyclosporin A and FK506 Blood 95 2000 2733 2741
    • (2000) Blood , vol.95 , pp. 2733-2741
    • Peters, D.1    Tsuchida, M.2    Manthei, E.R.3    Alam, T.4    Cho, C.S.5    Knechtle, S.J.6
  • 33
    • 0028817544 scopus 로고
    • Stimulation of transforming growth factor-beta(1) transcription by cyclosporine
    • Y. Prashar, A. Khanna, P. Sehajpal, V.K. Sharma, and M. Suthanthiran Stimulation of transforming growth factor-beta(1) transcription by cyclosporine FEBS Lett. 358 1995 109 112
    • (1995) FEBS Lett. , vol.358 , pp. 109-112
    • Prashar, Y.1    Khanna, A.2    Sehajpal, P.3    Sharma, V.K.4    Suthanthiran, M.5
  • 34
    • 0030973579 scopus 로고    scopus 로고
    • Transcription factors of the NFAT family - Regulation and function
    • A. Rao, C. Luo, and P.G. Hogan Transcription factors of the NFAT family - regulation and function Annu. Rev. Immun. 15 1997 707 747
    • (1997) Annu. Rev. Immun. , vol.15 , pp. 707-747
    • Rao, A.1    Luo, C.2    Hogan, P.G.3
  • 35
    • 0344011094 scopus 로고    scopus 로고
    • Intrinsic differences between authentic and cryptic 5′ splice sites
    • X. Roca, R. Sachidanandam, and A.R. Krainer Intrinsic differences between authentic and cryptic 5′ splice sites Nucleic Acids Res. 31 2003 6321 6333
    • (2003) Nucleic Acids Res. , vol.31 , pp. 6321-6333
    • Roca, X.1    Sachidanandam, R.2    Krainer, A.R.3
  • 36
    • 0037197864 scopus 로고    scopus 로고
    • Gene expression: The close coupling of transcription and splicing
    • E. Rosonina, and B.J. Blencowe Gene expression: the close coupling of transcription and splicing Curr. Biol. 12 2002 R319 R321
    • (2002) Curr. Biol. , vol.12
    • Rosonina, E.1    Blencowe, B.J.2
  • 37
    • 0034129915 scopus 로고    scopus 로고
    • The impact of immunosuppressive drugs on the analysis of T-cell activation
    • P. Rovira, L. Mascarell, and P. Truffa-Bachi The impact of immunosuppressive drugs on the analysis of T-cell activation Curr. Med. Chem. 7 2000 1 20
    • (2000) Curr. Med. Chem. , vol.7 , pp. 1-20
    • Rovira, P.1    Mascarell, L.2    Truffa-Bachi, P.3
  • 38
    • 0032852479 scopus 로고    scopus 로고
    • CREB: A stimulus-induced transcription factor activated by a diverse array of extracellular signals
    • A.J. Shaywitz, and M.E. Greenberg CREB: a stimulus-induced transcription factor activated by a diverse array of extracellular signals Annu. Rev. Biochem. 68 1999 821 861
    • (1999) Annu. Rev. Biochem. , vol.68 , pp. 821-861
    • Shaywitz, A.J.1    Greenberg, M.E.2
  • 39
    • 0024331682 scopus 로고
    • Identification of multiple cis-elements and trans-acting factors involved in the induced expression of human IL-2 gene
    • H. Shibuya, and T. Taniguchi Identification of multiple cis-elements and trans-acting factors involved in the induced expression of human IL-2 gene Nucleic Acids Res. 17 1989 9173 9184
    • (1989) Nucleic Acids Res. , vol.17 , pp. 9173-9184
    • Shibuya, H.1    Taniguchi, T.2
  • 41
    • 0029134905 scopus 로고
    • Incidence of de-novo breast cancer in women chronically immunosuppressed after organ transplantation
    • T. Stewart, S.C. Tsai, H. Grayson, R. Henderson, and G. Opelz Incidence of de-novo breast cancer in women chronically immunosuppressed after organ transplantation Lancet 346 1995 796 798
    • (1995) Lancet , vol.346 , pp. 796-798
    • Stewart, T.1    Tsai, S.C.2    Grayson, H.3    Henderson, R.4    Opelz, G.5
  • 42
    • 0030682419 scopus 로고    scopus 로고
    • The calcium/calmodulin-dependent protein phosphatase calcineurin is the major Elk-1 phosphatase
    • T. Sugimoto, S. Stewart, and K.L. Guan The calcium/calmodulin-dependent protein phosphatase calcineurin is the major Elk-1 phosphatase J. Biol. Chem. 272 1997 29415 29418
    • (1997) J. Biol. Chem. , vol.272 , pp. 29415-29418
    • Sugimoto, T.1    Stewart, S.2    Guan, K.L.3
  • 44
    • 0028153044 scopus 로고
    • Long-term benefits and risks of cyclosporin a (Sandimmun) - An analysis at 10 years
    • G. Thiel, A. Bock, M. Spondlin, F.P. Brunner, M. Mihatsch, and T. Rufli Long-term benefits and risks of cyclosporin A (Sandimmun) - an analysis at 10 years Transplant. Proc. 26 1994 2493 2498
    • (1994) Transplant. Proc. , vol.26 , pp. 2493-2498
    • Thiel, G.1    Bock, A.2    Spondlin, M.3    Brunner, F.P.4    Mihatsch, M.5    Rufli, T.6
  • 45
    • 0033551804 scopus 로고    scopus 로고
    • Protein kinase C and calcineurin synergize to activate IkappaB kinase and NF-kappaB in T lymphocytes
    • S.A. Trushin, K.N. Pennington, A. Algeciras-Schimnich, and C.V. Paya Protein kinase C and calcineurin synergize to activate IkappaB kinase and NF-kappaB in T lymphocytes J. Biol Chem. 274 1999 22923 22931
    • (1999) J. Biol Chem. , vol.274 , pp. 22923-22931
    • Trushin, S.A.1    Pennington, K.N.2    Algeciras-Schimnich, A.3    Paya, C.V.4
  • 46
    • 0028116286 scopus 로고
    • Cyclosporine a upregulates interleukin-6 gene expression in human gingiva: Possible mechanism for gingival overgrowth
    • M.S. Williamson, E.K. Miller, J. Plemons, T. Rees, and A.M. Iacopino Cyclosporine a upregulates interleukin-6 gene expression in human gingiva: possible mechanism for gingival overgrowth J. Periodontol. 65 1994 895 903
    • (1994) J. Periodontol. , vol.65 , pp. 895-903
    • Williamson, M.S.1    Miller, E.K.2    Plemons, J.3    Rees, T.4    Iacopino, A.M.5
  • 47
    • 0027198248 scopus 로고
    • Exon switching and activation of stromal and embryonic fibroblast growth factor (FGF)-FGF receptor genes in prostate epithelial cells accompany stromal independence and malignancy
    • G. Yan, Y. Fukabori, G. McBride, S. Nikolaropolous, and W.L. McKeehan Exon switching and activation of stromal and embryonic fibroblast growth factor (FGF)-FGF receptor genes in prostate epithelial cells accompany stromal independence and malignancy Mol. Cell. Biol. 13 1993 4513 4522
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 4513-4522
    • Yan, G.1    Fukabori, Y.2    McBride, G.3    Nikolaropolous, S.4    McKeehan, W.L.5
  • 48
    • 0027160003 scopus 로고
    • Distinct functions of SR proteins in alternative pre-mRNA splicing
    • A.M. Zahler, K.M. Neugebauer, W.S. Lane, and M.B. Roth Distinct functions of SR proteins in alternative pre-mRNA splicing Science 260 1993 219 222
    • (1993) Science , vol.260 , pp. 219-222
    • Zahler, A.M.1    Neugebauer, K.M.2    Lane, W.S.3    Roth, M.B.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.