The impact of immunosuppressive drugs on the analysis of T-cell activation

Current Medicinal Chemistry

Volumn 7, Issue 7, 2000, Pages 673-692

  Rovira, Paula ^a   Mascarell, Laurent ^a   Truffa Bachi, Paolo ^a  

^a INSTITUT PASTEUR   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CALCINEURIN; CYCLOPHILIN; CYCLOSPORIN A; IMMUNOSUPPRESSIVE AGENT; LEFLUNOMIDE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; RAPAMYCIN; TACROLIMUS;

DEPHOSPHORYLATION; DRUG BINDING; DRUG EFFICACY; DRUG MECHANISM; DRUG TARGETING; ENZYME ACTIVITY; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; ORGAN TRANSPLANTATION; QUALITY OF LIFE; REVIEW; T LYMPHOCYTE ACTIVATION;

EID: 0034129915     PISSN: 09298673     EISSN: None     Source Type: Journal    
DOI: 10.2174/0929867003374778     Document Type: Review

References (137)

1. Borel, J F., Feurer, C., Gubler, H.U., Stahelin, H. Agents and Actions, 1976, 6, 468-475.
2. Borel, J.F., Feurer, C., Magnee, C., Stahelin, H. Immunol., 1977, 32, 1017-1025.
3. Thiel, G., Bock, A., Spondlin, M., Brunner, F.P., Mihatsch, M., Rufli, T., Landmann, J. Transplant. Proc., 1994, 26, 2493-2498.
4. Stiller, C.R. Transplant. Proc., 1996, 28, 2005-2012.
5. Kino, T., Hatanaka, H., Hashimoto. M., Nichiyama, M., Gott, T., Okuhara, M., Aoki, H., Imaka, H. J. Antibiot. (Tokyo), 1987, 60, 1249-1255.
6. Sawada, S., Suzuki G., Y., K. F., T. J. Immunol., 1987, 139:, 1797-1803.
7. Starzl, T., Fung, J., Venkataramman, R., Todo, S., Demetris, A., Jain, A. Lancet, 1989, ii, 1000-1004.
8. Thomson, A.W. Immunol. Today, 1990, 11, 35-36.
9. Martel, R.R., Klicius, J., Galet, S. Can. J. Physi. Pharm., 1977, 55, 48-51.
10. Brazelton, T.R., Morris, R.E. Curr. Opin. Immunol., 1996, 8, 710-720.
11. Borel, J.F., Baumann, G., Chapman, I, Donatsch, P., Fahr, A., Mueller, E.A., Vigouret, J.-M. Adv. Pharmacol., 1996, 35. 115-245.
12. Sigal, N.H., Dumont, F.J. Annu. Rev. Immunol., 1992, 10, 519-560.
13. Berridge, M.J., Irvine, R.F. Nature, 1984, 312, 315-321.
14. Nishizuka, Y. Science. 1984, 225, 1365-1370.
15. Ullman, K.S., Northrop, J.P., Verweij, C.L., Crabtree, G.R. Annu. Rev. Immunol., 1990, 8, 421-452.
16. Krönke, M., Leonard, W.J., Depper, J.M., Arya, S.K., Wong-Staal, F., Gallo, R.C., Waldmann, T.A., Greene, W.C. Proc. Natl. Acad. Sci. USA, 1984, 81, 5214-5218.
17. Williams, T.M., Eisenberg, L., Burlein, J.E., Norris, C.A., Pancer, S., Yao, D., Burger, S., Kamoun, M., Kant, J. J. Immunol., 1988, 141, 662-666.
18. Jain, J., Loh, C., Rao, A. Curr. Opin. Immunol., 1995, 7, 333-342.
19. Jain, J.N., McCaffrey, P.G., Miner, Z., Kerppola, T.K., Lambert, J.N., Verdine, G.L., Curran, T., Rao, A. Nature, 1993, 365, 352-355.
20. de Grazia, U., Felli, M.P., Vacca, A., Farina, A.R., Maroder, M., Cappabianca, L., Meco, D., Farina, M., Screpanti, I., Frati, L. J. Exp. Med., 1994, 180, 1485-1497.
21. Ullman, K.S., Northrop, J.P., Admon, A., Crabtree, G.R. Genes & Dev., 1993, 7, 188-196.
22. Crabtree, G.R., Clipstone, N.A. Annu. Rev. Biochem., 1994, 63, 1045-1083.
23. Fraser. J.D.I., B. A. Crabtree, G. R., Weiss, A. Science, 1991, 251, 313-316.
24. Manger, B., Hardy, K.J., Weiss, A., Stobo, J.D. J. Clin. Invest., 1986, 77, 1501-1506.
25. Metcalfe, S. Transplantation, 1984, 38, 161-164.
26. Handschumacher, R.E., Harding, M.W., Rice, J., Drugge, R.J., Speicher, D.W. Science, 1984, 226, 544-547.
27. Harding, M.W., Handschumacher, R.E., Speicher, D.W. J Biochem. Chem., 1986, 261, 8547-8555.
28. Haendler, B., Hofer-Warbinek, R., Hofer, E. EMBO J., 1987, 6, 947-950.
29. Galat, A. Eur. J. Biochem., 1993, 216, 689-707.
30. Fischer, G., Wittmann-Liebold, B., Lang, K., Kiefhaber. T., Schmid, F.X. Nature, 1989, 337, 476-478.
31. Takahashi. N., Hayano, T., Suzuki, M Nature, 1989, 337, 473-475.
32. Lang, K., Schmid, F.X., Fischer, G. Nature, 1987, 329, 268-270.
33. Sigal, N.H., Dumont, F., Durette, P., Siekierka, J.J., Peterson, L., Rich, D.H., Dunlap, B.E., Staruch, M.J., Melino, M.R., Koprak, S.L. J. Exp. Med., 1991, 173, 619-628.
34. Tocci, M.J., Matkovich, D.A., Collier. K., Kwok, P., Dumont, F., Lin, S., S., D., Siekierka, J.J., Chin, J., Hutchinson, N.I. J. Immunol., 1989, 143, 718-726.
35. Harding, M.W., Galat, A., Uehling, D.E., Schreiber, S.L. Nature, 1989, 341, 758-760.
36. Siekierka, J.J., Hung, S.H.Y., Poe, M., Shirley Lin, C., Sigal, N.H. Nature, 1989 341, 755-757.
37. Maki, N., Sekiguchi, F., Nishimaki, J., Miwa, K., Hayano, T., Takahashi, N., Suzuki, M. Proc. Natl. Acad. Sci. USA, 1990, 87, 5440-5443.
38. Standaert, R.F., Galat, A., Verdine, G.L., Schreiber, S.L. Nature, 1990, 346, 671-674.
39. Tropschug, M., Wachter, E., Mayer, S., Schönbrunner, E.R., Schmid, F.X. Nature, 1990, 346, 674-677.
40. Bierer, B.E., Mattila, P.S., Standaert, R.F., Herzenberg, L.A., Burakoff, S.J., Crabtree, G., Schreiber, S.L. Proc. Natl. Acad. Sci. USA, 1990. 87, 9231-9235.
41. Liu, J , Farmer, J.D., Lane, W.S., Friedman, J., Weissman, I., Schreiber, S.L. Cell, 1991, 66, 807-815.
42. Kincaid, R.L., Takayama, H., Billingsley, M.L., Sitkovsky, M.V. Nature, 1987, 300, 176-178.
43. Fruman, D.A., Klee, C.B., Bierer, B.E., Burakoff, S.J. Proc. Natl. Acad. Sci. USA, 1992, 89, 3686-3690.
44. Clipstone, N.A., Crabtree, G.R. Nature, 1992, 357, 695-697.
45. O'Keefe, S., Tamura, J., Kincaid, R., Tocci, M., EA, O.N. Nature, 1992, 357, 692-694.
46. Klee, C.B., Crouch, T.H., Krinks. M.H. Biochem., 1979, 18, 722-729.
47. Kincaid, R.L. J. All, Clin. Immunol., 1995, 96, 1170-1177
48. Hubbard, M.J., Klee, C.B. Biochem., 1989, 28, 1868-1874.
49. Clipstone, N.A., Crabtree, G.R. Immunosuppressive and Antiinflammatory Drugs, 1993, PP. 20-30.
50. Swanson, S.K.H., Born, T., Zydowsky, L D., Cho H.J . Chang. H.Y., Walsh, C.T., Rusnak. F. Proc. Natl. Acad. Sci. USA, 1992, 89, 3741-3745.
51. Schreiber, S.L., Crabtree, G.R. Immunol. Today, 1992, 13, 136-142.
52. Siebenlist, U., Durand, D.B., Bressler, P , Holbrook, N.J., Norris, C.A., Kamoun, M., Kant, J., Crabtree, G. Mol. Cell. Biol., 1986, 6, 3042-3049.
53. Shaw, J.P., Utz, P.J., Durand, D.B., Toole, J.J., Emmel, E.A., Crabtree, G.R. Science, 1988, 247, 202-205.
54. Brabletz, T., Pietrowski, I., Serfling, E. Nucleic Acids Research, 1991, 19, 61-67.
55. Emmel, E.A., Verweij, C.L., Durand, D.B., Higgins, K.M., Lacy, E., Crabtree, G.R. Science, 1989, 246, 1617-1620.
56. Mattila, P.S., Ullman, K.S., Fiering, S., Emmel, E.A., McCutcheon, M., Crabtree, G.R., Herzenberg, L.A. EMBO J., 1990, 9, 4425-4433.
57. Flanagan, W.M., Corthésy, B., Bram, R.J., Crabtree, G. Nature, 1991, 352, 803-807.
58. Jain, J., Valge-Archer, V.E., Rao, A. J. Immunol., 1992, 148, 1240-1250.
59. Castigli, E., Chatila, T,A., Geha, R.S. J. Immunol., 1993, 150, 3284-3290.
60. McCaffrey, P.G., Luo, C., Kerppola, T.K., Jain, J., Badalian, T.M., Ho, A.M., Burgeon, E., Lane, W.S., Lambert, J.N., Curran, T. Science, 1993, 262, 750-754.
61. Northrop, J.P., Ullman, K.S., Crabtree, G.R. J. Biol. Chem., 1993, 268, 2917-2923.
62. McCaffrey, P.G., Perrino, B.A., Soderling, T.R., Rao, A. J. Biol. Chem., 1993, 268, 3747-3752.
63. Hoey, T., Sun, Y.L., Williamson, K., Xu, X. Immunity, 1995, 2, 461-472.
64. Masuda, E S., Naito, Y., Tokumitsu, H., Campbell, D., Saito, F., Hannum, C., Arai, K.I., Arai, N. Mol. Cell. Biol., 1995, 15, 2697-2706.
65. Northrop, J.P., Ho, S.N., Chen, L., Thomas, D.J., Timmerman, L.A., Nolan, G.P., Admon, A., Crabtree, G.R. Nature, 1994, 369, 497-502.
66. Rao, A., Luo, C., Hogan, P.G. Anna. Rev. Immunol, 1997, 15, 707-747.
67. Luo, C., Shaw, K T.Y., Raghavan, A., Aramburu, J., Garciacozar, F., Perrino, B A., Hogan, P.G., Rao, A. Proc. Natl. Acad. Sci. USA, 1996, 93, 8907-8912.
68. Tjian, R., Maniatis, T. Cell, 1994, 77, 5-8.
69. Kunkl, A., Klaus, G.G.B. J. Immunol., 1980, 125, 2526-2531.
70. Hess, A.D., Colombani, P.N. Ann. Inst. Pasteur/Immunol., 1987, 138, 161-167.
71. Bemer, V., Motta, I., Perret, R., Truffa-Bachi, P. Eur. J. Immunol., 1995, 25, 3394-3401.
72. Motta, I., Galelli, A., Colle, J., Truffa-Bachi, P. Transplant. Proc., 1991, 23, 2958-2959.
73. Motta, I., Colle, J.H., Shidani, B., Truffa-Bach, P. Eur. J. Immunol., 1991, 21, 551-557.
74. Pereira, G., Miller. J., Shevach, E. J. Immunol., 1990, 144, 2109-2116.
75. Shidani, B., Motta, I., Truffa-Bachi, P. Eur. J. Immunol., 1987, 17, 291-294.
76. Bemer, V., Truffa-Bachi, P. Eur. J. Immunol., 1996, 26, 1481-1488.
77. Jain, J., McCaffrey, P.G., Valge-Archer, V.E., Rao, A. Nature, 1992, 356, 801-804.
78. Jain, J., Valge-Archer, V.E., Sinskey, A.J., Rao, A. J. Exp. Med., 1992, 175, 853-862.
79. June, C.H., Ledbetter, J.A., Gillespie, M.M., Lindsten, T., Thompson, C.B. Mol. Cell. Biol., 1987, 7, 4472.
80. Bloemena, E., Van Oers, R.H.J., Weinreich, S., Stilma-Meinesz, A.P., Schellekens, P.T.A., Van Lier, R.A.W. Eur. J. Immunol., 1989, 19, 943-946.
81. Ward, S.G. Biochem. J., 1996, 318, 361-377,
82. Gunter, K.C., Irving, S.G., Zipfel, P.F., Siebenlist, U., Kelly, K. J. Immunol., 1989, 142, 3286-3291.
83. Mercep, M., Noguchi, P.D., Ashwell, J.D. J. Immunol., 1989, 142, 4085-4092.
84. Shi, Y., Sahai, B.M., Green, D.R. Nature, 1989, 339, 625-626.
85. Fruman, D.A., Mather, P.E., Burakoff, S.J., Bierer, B.E. Eur. J. Immunol., 1992, 22, 2513-2517.
86. Gao, E.K., Lo, D., Cheney, R., Kanagawa, O., Sprent, J. Nature, 1988, 336, 176-179.
87. Zacharchuk, C.M., Mercep, M., Chakraborti, P.K., Simons, S.S., Jr., Ashwell, J.D. J. Immunol., 1990, 145, 4037-4045.
88. Liu, Z.G., Smith, S.W., McLaughlin, K.A., Schwartz, L.M., Osbome, B.A. Nature, 1994, 367, 281-284.
89. Woronicz, J.D., Calnan, B., Ngo, V., Winoto, A. Nature, 1994, 367, 277-281.
90. Yazdanbakhsh, K., Choi, J.-W., Li, Y., Lau, L.F., Choi, Y. Proc. Natl. Acad. Sci. USA, 1995, 92, 437-441.
91. Woronicz, J.D., Lina, A., Calnan, B.J., Szychowski, S., Cheng, L., Winoto, A. Mol. Cell. Biol., 1995, 15, 6364-6376.
92. Abraham, R.T., Wiederrecht, G.J. Annu. Rev. Immunol., 1996, 14, 483-510.
93. Dumont, F.J., Su, Q.X. Life Sciences, 1996, 58, 373-395.
94. Dumont, F.J., Staruch, M.J., Koprak, S.L., Melino, M.R., Sigal, N.H. J. Immunol., 1990, 144, 251-258.
95. Bierer, B.E., Schreiber, S.L., Burakoff, S.J. Eur. J. Immunol., 1991, 21, 439-445.
96. Dumont, F.J., Melino, M.R., Staruch, M.J., Koprak, S.L., Fischer, P.A., Sigal, N.H. J. Immunol., 1990, 144, 1418-1424.
97. Bierer, B.E., Somers, P.K., Wandless, T.J., Burakoff, SJ., Schreiber, S.L. Science, 1990, 250, 556-559.
98. Chung, J., Kuo, C.J., Crabtree, G.R., Blenis, J. Cell, 1992, 69, 1227-1236.
99. Kuo, C.J., Chung, J., Fiorentino, D.F., Flanagan, W.M., Blenis, J., Crabtree, G.R. Nature, 1992, 358, 70-73.
100. Price, D.J., Grove, J.R., Calvo, V., Avruch, J., Bierer, B.E. Science, 1992, 257, 973-977.
101. Heitman, J., Koller, A., Kunz, J., Henriquez, R., Schmidt, A., Movva, N.R., Hall, M.N. Mol. Cell. Biol., 1993, 13, 5010-5019.
102. Lorenz, M.C., Heitman, J. J. Biol. Chem., 1995, 270, 27531-27537.
103. Keith, C.T., Schreiber, S.L. Science, 1995, 270, 50-51.
104. Brown, E.J., Albers, M.W., Shin, T.B., Ichikawa, K., Keith, C.T., Lane, W.S., Schreiber, S.L. Nature, 1994, 369, 756-758.
105. Chiu, M.I., Katz, H., Berlin, V. Proc. Natl. Acad. Sci. USA, 1994, 91, 12574-12578.
106. Sabatini, D.M., Erdjumentbromage. H., Lui, M., Tempst, P., Snyder, S. H. Cell, 1994, 78, 35-43.
107. Sabers, C.J., Martin, M.M., Brunn, G.J., Williams, J.M., Dumont, F.J., Wiederrecht, G., Abraham, R.T. J. 1995, Biol. Chem., 270, 815-822.
108. Morice, W.G., Brunn, G.J., Wiederrecht, G., Siekierka, J.J., Abraham, R.T. J. Biol. Chem., 1993, 268, 3734-3738.
109. Morice, W.G., Wiederrecht, G., Brunn, G.J., Siekierka, J.J., Abraham, R.T. J. Biol. Chem., 1993, 268, 22737-22745.
110. Nourse, J., Firpo, E., Flanagan, W.M., Coats, S., Polyak, K., Lee, M.H , Massague, J., Crabtree, G.R., Roberts, J.M. Nature, 1994, 372, 570-573.
111. Sherr, C.J., Roberts, J.M. Genes & Dev., 1995, 9, 1149-1163.
112. Thomson, A.W., Starzl, T.E. Immunol. Rev., 1993, 136, 71-98.
113. Braun, W., Kallen, J., Mikol, V., Walkinshaw, M.D., Wuthrich, K. FASEB J., 1995, 9, 63-72.
114. Stoddard, B.L., Flick, K.E. Curr. Opin. Struct. Biol., 1996, 6, 770-775.
115. Ke, H.M., Zhao, Y.D., Luo, F., Weissman, I., Friedman, J. Proc. Natl, Acad, Sci. USA, 1993, 90, 11850-11854.
116. Mikol, V., Kallen, J., Pflugl, G., Walkinshaw, M.D. J. Mol. Biol, 1993, 234, 1119-1130.
117. Theriault, Y , Logan. T.M., Meadows, R., Yu, L.P., Olejniczak, E.T., Holzman, T.F., Simmer, R.L., Fesik, S.W. Nature, 1993, 367, 88-91.
118. Pflugl, G., Kallen, J., Schirmer, T., Jansonius, J.N., Zurini, M G.M., Walkinshaw, M.D. Nature, 1993, 361, 91-94.
119. Van Duyne, G.D., Standaert, R.F., Schreiber, S.L, Clardy, J. J. Am. Chem. Soc., 1991, 113, 7433-7434.
120. Griffith, J.P., Kim, J.L., Kirn, E.E., Sintchak, M.D., Thomson, J.A., Fitzgibbon, M.J., Fleming, M.A., Caron, P.R., Hsiao, K., Navia, M.A. Cell, 1995, 82, 507-522.
121. Kissinger, C.R., Parge, H.E., Knighton, D.R., Lewis, C.T., Pelletier, L.A., Tempczyk, A., Kalish, V.J., Tucker, K.D., Showalter, R.E., Moomaw, E.W. Nature, 1995, 378, 641-644.
122. Choi, J W., Chen, J., Schreiber, S.L, Clardy, J. Science, 1996, 273, 239-242.
123. Hao, L., Calcinaro, F., Gill, R.G., Eugui, E.M., Allison, A.C., Lafferty, K.J. Transplantation, 1992, 53, 590-595.
124. Lang, R., Wagner, H., Heeg, K. Transplantation, 1995, 59, 382-389.
125. Silva Jr. H.T., Morris, R.E. Am. J. Med. Sci., 1997, 313, 289-301.
126. Dittmann, J., Wenger, R., Kleinkauf. H., Lawen, A. J Biochem. Chem., 1994, 269, 2841-2846.
127. Hilbrands, L.B., Hoitsma, A.J., Koene, R.A. Transplant. 1995, 59, 1263-1270.
128. Stewart, T., Tsai, S.C., Grayson, H., Henderson, R., Opelz, G. Lancet 1995, 346, 796-798.
129. Tanner, J.E., Alfieri, C. Leukemia & Lymphoma 1996, 21, 379-390.
130. Beatty, P.R., Krams, S.M., Esquivel, C.O., Martinez, O.M. Transplant. 1998, 65, 1248-1255.
131. Letterio, J.J., Roberts, A.B. Annu. Rev. Immunol. 1998, 16, 137-161.
132. Li, B., Sehajpal, P.K., Khanna, A., Vlassara, H., Cerami, A., Stenzel, K.H., Suthanthiran, M. J. Exp. Med. 1991, 174, 1259-1262.
133. Prashar, Y., Khanna, A., Sehajpal, P., Sharma, V.K., Suthanthiran, M. FEBS Lett. 1995, 358, 109-112.
134. Khanna, A., Li, B., Stenzel, K.H., Suthanthiran, M. Transplant. 1994, 57, 577-582.
135. Shin, G.T., Khanna, A., Ding, R., Sharma, V.K., Lagman, M., Li, B., Suthanthiran, M. Transplant. 1998, 65, 313-318.
136. Hojo, M., Morimoto, T., Maluccio, M., Asano, T., Morimoto, K., Lagman, M., Shimbo, T., Suthanthiran, M. Nature 1999, 397, 530-534.
137. Kahan, B.D. Transplant. Proc. 1998, 30, 2493-2496.